Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease

Neuroscience

Volumn 97, Issue 2, 2000, Pages 207-210

  Buttini, M ^a,b   Akeefe, H ^a   Lin, C ^a   Mahley, R W ^a,b,c   Pitas, R E ^a,b   Wyss Coray, T ^a,b   Mucke, L ^a,b  

^a GLADSTONE INSTITUTES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; Apolipoprotein E; Dominant negative; Excitotoxicity; Neurodegeneration; Transgenic mice

Indexed keywords

APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; MICROTUBULE ASSOCIATED PROTEIN 2; SYNAPTOPHYSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; HETEROZYGOSITY; HOMOZYGOSITY; KNOCKOUT MOUSE; MOUSE; NERVE DEGENERATION; NEUROFILAMENT; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; ANIMALS; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; AXONS; BRAIN; DENDRITES; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; NEURODEGENERATIVE DISEASES; NEUROPROTECTIVE AGENTS; PRESYNAPTIC TERMINALS; SYNAPTOPHYSIN;

EID: 0034055035     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00069-5     Document Type: Article

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