메뉴 건너뛰기




Volumn 1, Issue 7, 2003, Pages 1663-1670

Diverse role of LDL receptor-related protein in the clearance of proteases and in signaling

Author keywords

LRP; PDGF; Proteases; Serpin

Indexed keywords

LIGAND; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; PROTEINASE; SERINE PROTEINASE INHIBITOR; TYROSINE;

EID: 0141832797     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1046/j.1538-7836.2003.00330.x     Document Type: Review
Times cited : (106)

References (94)
  • 1
    • 0001665337 scopus 로고
    • Surface location and high affinity for calcium of a 500kDa liver membrane protein closely related to the LDL-receptor suggest a physiolocical role as lipoprotein receptor
    • Herz J, Hamann U, Rogne S, Myklebost O, Gausepohl H, Stanley KK. Surface location and high affinity for calcium of a 500kDa liver membrane protein closely related to the LDL-receptor suggest a physiolocical role as lipoprotein receptor. EMBO J 1988; 7: 4119-27.
    • (1988) EMBO J , vol.7 , pp. 4119-4127
    • Herz, J.1    Hamann, U.2    Rogne, S.3    Myklebost, O.4    Gausepohl, H.5    Stanley, K.K.6
  • 2
    • 0025369190 scopus 로고
    • Proteolytic processing of the 600 kD low density liprotein receptor related protein LRP occurs in a trans-Golgi compartment
    • Herz J, Kowal RC, Goldstein JL, Brown MS. Proteolytic processing of the 600 kD low density liprotein receptor related protein LRP occurs in a trans-Golgi compartment. EMBO J 1990; 9: 1769-76.
    • (1990) EMBO J , vol.9 , pp. 1769-1776
    • Herz, J.1    Kowal, R.C.2    Goldstein, J.L.3    Brown, M.S.4
  • 3
    • 0024449363 scopus 로고
    • The LDL-receptor related protein, LRP, is an apolipoprotein E binding protein
    • Beisiegel U, WeberW, Ihrke G, Herz J, Stanley KK. The LDL-receptor related protein, LRP, is an apolipoprotein E binding protein. Nature 1989; 341: 162-4.
    • (1989) Nature , vol.341 , pp. 162-164
    • Beisiegel, U.1    Weber, W.2    Ihrke, G.3    Herz, J.4    Stanley, K.K.5
  • 4
    • 0040177065 scopus 로고
    • Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins
    • Kowal RC, Herz J, Goldstein JL, Esser V, Brown MS. Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins. Proc Natl Acad Sci USA 1989; 86: 5810-4.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5810-5814
    • Kowal, R.C.1    Herz, J.2    Goldstein, J.L.3    Esser, V.4    Brown, M.S.5
  • 5
    • 0032004972 scopus 로고    scopus 로고
    • Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants
    • Rohlmann A,Gotthardt M, Hammer RE, Herz J. Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants. J Clin Invest 1998; 101: 689-95.
    • (1998) J Clin Invest , vol.101 , pp. 689-695
    • Rohlmann, A.1    Gotthardt, M.2    Hammer, R.E.3    Herz, J.4
  • 6
    • 0025231645 scopus 로고
    • The human α2-macroglobulin receptor: identification of a 420-kD cell surface glycoprotein specific for the activated conformation of α2-macroglobulin
    • Ashcom JD, Tiller SE, Dickerson K, Cravens JL, Argraves WS, Strickland DK. The human α2-macroglobulin receptor: identification of a 420-kD cell surface glycoprotein specific for the activated conformation of α2-macroglobulin. J Cell Biol 1990; 110: 1041-8.
    • (1990) J Cell Biol , vol.110 , pp. 1041-1048
    • Ashcom, J.D.1    Tiller, S.E.2    Dickerson, K.3    Cravens, J.L.4    Argraves, W.S.5    Strickland, D.K.6
  • 7
    • 0024971241 scopus 로고
    • Purification of the rat hepatic α2-macroglobulin receptor as an approximately 440 kda single chain polypeptide
    • Moestrup SK, Gliemann J. Purification of the rat hepatic α2-macroglobulin receptor as an approximately 440 kda single chain polypeptide. J Biol Chem 1989; 264: 15574-7.
    • (1989) J Biol Chem , vol.264 , pp. 15574-15577
    • Moestrup, S.K.1    Gliemann, J.2
  • 8
    • 0025080835 scopus 로고
    • Sequence identity between the α2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor
    • Strickland DK, Ashcom JD, Williams S, Burgess WH, Migliorini M, Argraves WS. Sequence identity between the α2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor. J Biol Chem 1990; 265: 17401-4.
    • (1990) J Biol Chem , vol.265 , pp. 17401-17404
    • Strickland, D.K.1    Ashcom, J.D.2    Williams, S.3    Burgess, W.H.4    Migliorini, M.5    Argraves, W.S.6
  • 11
    • 0024407459 scopus 로고
    • Purification of the human placental α2-macroglobulin receptor
    • Jensen PH, Moestrup SK, Gliemann J. Purification of the human placental α2-macroglobulin receptor. FEBS Lett 1989; 255: 275-80.
    • (1989) FEBS Lett , vol.255 , pp. 275-280
    • Jensen, P.H.1    Moestrup, S.K.2    Gliemann, J.3
  • 12
    • 0028933638 scopus 로고
    • Sites within the 39-kDa protein important for regulating ligand bindng to the low density lipoprotein receptor-related protein
    • Warshawsky I, Bu G, Schwartz AL. Sites within the 39-kDa protein important for regulating ligand bindng to the low density lipoprotein receptor-related protein. Biochemistry 1995; 34: 3404-15.
    • (1995) Biochemistry , vol.34 , pp. 3404-3415
    • Warshawsky, I.1    Bu, G.2    Schwartz, A.L.3
  • 15
    • 0030739440 scopus 로고    scopus 로고
    • The solution structure of the N-terminal domain of alpha2-macroglobulin receptor-associated protein
    • Nielsen PR, Ellgaard L, Etzerodt M, Thogersen HC, Poulsen FM. The solution structure of the N-terminal domain of alpha2-macroglobulin receptor-associated protein. Proc Natl Acad Sci USA 1997; 94: 7521-5.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 7521-7525
    • Nielsen, P.R.1    Ellgaard, L.2    Etzerodt, M.3    Thogersen, H.C.4    Poulsen, F.M.5
  • 16
    • 0027269902 scopus 로고
    • Biosynthesis of the gp330/44-kDa Heymann nephritis antigenic complex: assembly takes place in the ER
    • Biemesderfer D, Dekan G, Aronson PS, Farquhar MG. Biosynthesis of the gp330/44-kDa Heymann nephritis antigenic complex: assembly takes place in the ER. Am J Physiol 1993; 264: F1011-F1020.
    • (1993) Am J Physiol , vol.264
    • Biemesderfer, D.1    Dekan, G.2    Aronson, P.S.3    Farquhar, M.G.4
  • 17
    • 0028988551 scopus 로고
    • 39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein
    • Bu G, Geuze HJ, Strous GJ, Schwartz AL. 39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein. EMBO J 1995; 14: 2269-80.
    • (1995) EMBO J , vol.14 , pp. 2269-2280
    • Bu, G.1    Geuze, H.J.2    Strous, G.J.3    Schwartz, A.L.4
  • 18
    • 0029887302 scopus 로고    scopus 로고
    • RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors
    • Willnow TE, Rohlmann A, Horton J, Otani H, Braun JR, Hammer RE, Herz J. RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors. EMBO J 1996; 15: 2632-9.
    • (1996) EMBO J , vol.15 , pp. 2632-2639
    • Willnow, T.E.1    Rohlmann, A.2    Horton, J.3    Otani, H.4    Braun, J.R.5    Hammer, R.E.6    Herz, J.7
  • 20
    • 0026793036 scopus 로고
    • A novel mechanism for controlling the activity of α2-macroglobulin receptor/ low density lipoprotein receptor-related protein Multiple regulatory sites for 39-kDa receptor-associated protein
    • Williams SE, Ashcom JD, Argraves WS, Strickland DK. A novel mechanism for controlling the activity of α2-macroglobulin receptor/ low density lipoprotein receptor-related protein. Multiple regulatory sites for 39-kDa receptor-associated protein. J Biol Chem 1992; 267: 9035-40.
    • (1992) J Biol Chem , vol.267 , pp. 9035-9040
    • Williams, S.E.1    Ashcom, J.D.2    Argraves, W.S.3    Strickland, D.K.4
  • 21
    • 0035914457 scopus 로고    scopus 로고
    • Recognition of alpha 2-macroglobulin by the low density lipoprotein receptor-related protein requires the cooperation of two ligand binding cluster regions
    • Mikhailenko I, Battey FD, Migliorini M, Ruiz JF, Argraves K, Moayeri M, Strickland DK. Recognition of alpha 2-macroglobulin by the low density lipoprotein receptor-related protein requires the cooperation of two ligand binding cluster regions. J Biol Chem 2001; 276: 39484-91.
    • (2001) J Biol Chem , vol.276 , pp. 39484-39491
    • Mikhailenko, I.1    Battey, F.D.2    Migliorini, M.3    Ruiz, J.F.4    Argraves, K.5    Moayeri, M.6    Strickland, D.K.7
  • 22
    • 0030945761 scopus 로고    scopus 로고
    • Molecular analysis of ligand binding to the second cluster of complement-type repeats fothe low density lipoprotein receptor-related protein: Evidence for an allosteric component in receptor-associated protein mediated inhibition of ligand binding
    • Horn IR, van den Berg BMM, van der Meijden PZ, Pannekoek H, van Zonneveld A-J. Molecular analysis of ligand binding to the second cluster of complement-type repeats fothe low density lipoprotein receptor-related protein: Evidence for an allosteric component in receptor-associated protein mediated inhibition of ligand binding. J Biol Chem 1997; 272: 13608-13.
    • (1997) J Biol Chem , vol.272 , pp. 13608-13613
    • Horn, I.R.1    van den Berg, B.M.M.2    van der Meijden, P.Z.3    Pannekoek, H.4    van Zonneveld, A.-J.5
  • 23
    • 0036271051 scopus 로고    scopus 로고
    • Orchestration of coagulation protease signaling by tissue factor
    • Riewald M, Ruf W. Orchestration of coagulation protease signaling by tissue factor. Trends Cardiovasc Med 2002; 12: 149-54.
    • (2002) Trends Cardiovasc Med , vol.12 , pp. 149-154
    • Riewald, M.1    Ruf, W.2
  • 25
    • 0030020590 scopus 로고    scopus 로고
    • In situ detection of tissue factor in vascular endothelial cells: correlation with the malignant phenotype of human breast disease
    • Contrino J, Hair G, Kreutzer DL, Rickles FR. In situ detection of tissue factor in vascular endothelial cells: correlation with the malignant phenotype of human breast disease. Nat Med 1996; 2: 209-15.
    • (1996) Nat Med , vol.2 , pp. 209-215
    • Contrino, J.1    Hair, G.2    Kreutzer, D.L.3    Rickles, F.R.4
  • 26
    • 0000348593 scopus 로고    scopus 로고
    • Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis
    • Mueller BM, Ruf W. Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis. J Clin Invest 1998; 101: 1372-8.
    • (1998) J Clin Invest , vol.101 , pp. 1372-1378
    • Mueller, B.M.1    Ruf, W.2
  • 27
    • 0024543984 scopus 로고
    • Functional significance of the Kunitz-type inhibitory domains of lipoprotein-associated coagulation inhibitor
    • Girard TJ,Warren LA, NovotnyWF, Likert KM, Brown SG, Miletich JP, Broze GJ Jr. Functional significance of the Kunitz-type inhibitory domains of lipoprotein-associated coagulation inhibitor. Nature 1989; 338 (6215): 518-20.
    • (1989) Nature , vol.338 , Issue.6215 , pp. 518-520
    • Girard, T.J.1    Warren, L.A.2    Novotny, W.F.3    Likert, K.M.4    Brown, S.G.5    Miletich, J.P.6    Broze Jr., G.J.7
  • 28
    • 0026668480 scopus 로고
    • Tissue factor pathway inhibitor: the carboxy-terminus is required for optimal inhibition of factor Xa
    • Wesselschmidt R, Likert K, Girard T, Wun TC, Broze GJ Jr. Tissue factor pathway inhibitor: the carboxy-terminus is required for optimal inhibition of factor Xa. Blood 1992; 79: 2004-10.
    • (1992) Blood , vol.79 , pp. 2004-2010
    • Wesselschmidt, R.1    Likert, K.2    Girard, T.3    Wun, T.C.4    Broze Jr., G.J.5
  • 29
    • 0028355715 scopus 로고
    • The low density lipoprotein receptor-related protein mediates the cellular degradation of tissue factor pathway inhibitor
    • Warshawsky I, Broze GJ Jr, Schwartz AL. The low density lipoprotein receptor-related protein mediates the cellular degradation of tissue factor pathway inhibitor. Proc Natl Acad Sci USA 1994; 91: 6664-8.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6664-6668
    • Warshawsky, I.1    Broze Jr., G.J.2    Schwartz, A.L.3
  • 30
    • 0029860084 scopus 로고    scopus 로고
    • The low density lipoprotein receptor-related protein can function independently from heparan sulfate proteoglycans in tissue factor pathway inhibitor endocytosis
    • Warshawsky I, Herz J, Broze GJ Jr, Schwartz AL. The low density lipoprotein receptor-related protein can function independently from heparan sulfate proteoglycans in tissue factor pathway inhibitor endocytosis. J Biol Chem 1996; 271: 25873-9.
    • (1996) J Biol Chem , vol.271 , pp. 25873-25879
    • Warshawsky, I.1    Herz, J.2    Broze Jr., G.J.3    Schwartz, A.L.4
  • 31
    • 0033582516 scopus 로고    scopus 로고
    • Down-regulation of monocyte tissue factor mediated by tissue factor pathway inhibitor and the low density lipoprotein receptor-related protein
    • Hamik A, Setiadi H, Bu G, McEver RP, Morrissey JH. Down-regulation of monocyte tissue factor mediated by tissue factor pathway inhibitor and the low density lipoprotein receptor-related protein. J Biol Chem 1999; 274: 4962-9.
    • (1999) J Biol Chem , vol.274 , pp. 4962-4969
    • Hamik, A.1    Setiadi, H.2    Bu, G.3    McEver, R.P.4    Morrissey, J.H.5
  • 32
    • 0032696798 scopus 로고    scopus 로고
    • Regulation of factor VIII expression and activity by von Willebrand factor
    • Kaufman RJ, Pipe SW. Regulation of factor VIII expression and activity by von Willebrand factor. Thromb Haemost 1999; 82: 201-8.
    • (1999) Thromb Haemost , vol.82 , pp. 201-208
    • Kaufman, R.J.1    Pipe, S.W.2
  • 33
    • 0030800963 scopus 로고    scopus 로고
    • The acidic region of the factor VIII light chain and the C2 domain together form the high affinity binding site for von willebrand factor
    • Saenko EL, Scandella D. The acidic region of the factor VIII light chain and the C2 domain together form the high affinity binding site for von willebrand factor. J Biol Chem 1997; 272: 18007-14.
    • (1997) J Biol Chem , vol.272 , pp. 18007-18014
    • Saenko, E.L.1    Scandella, D.2
  • 35
    • 0033621486 scopus 로고    scopus 로고
    • Role of the low density lipoprotein-related protein receptor in mediation of factor VIII catabolism
    • Saenko EL, Yakhyaev AV, Mikhailenko I, Strickland DK, Sarafanov AG. Role of the low density lipoprotein-related protein receptor in mediation of factor VIII catabolism. J Biol Chem 1999; 274: 37685-92.
    • (1999) J Biol Chem , vol.274 , pp. 37685-37692
    • Saenko, E.L.1    Yakhyaev, A.V.2    Mikhailenko, I.3    Strickland, D.K.4    Sarafanov, A.G.5
  • 37
    • 0034670013 scopus 로고    scopus 로고
    • Activation of factor IX zymogen results in exposure of a binding site for low-density lipoprotein receptor-related protein
    • Neels JG, van Den Berg BM, Mertens K, ter Maat H, Pannekoek H, Van Zonneveld AJ, Lenting PJ. Activation of factor IX zymogen results in exposure of a binding site for low-density lipoprotein receptor-related protein. Blood 2000; 96: 3459-65.
    • (2000) Blood , vol.96 , pp. 3459-3465
    • Neels, J.G.1    van Den Berg, B.M.2    Mertens, K.3    ter Maat, H.4    Pannekoek, H.5    Van Zonneveld, A.J.6    Lenting, P.J.7
  • 39
    • 0015167817 scopus 로고
    • In vivo interaction beween trypsin and some plasma proteins in relation to tolerance to intravenous infusion of trypsin in dog
    • Ohlsson K, Ganrot PO, Laurell CB. In vivo interaction beween trypsin and some plasma proteins in relation to tolerance to intravenous infusion of trypsin in dog. Acta Chir Scand 1971; 137: 113-21.
    • (1971) Acta Chir Scand , vol.137 , pp. 113-121
    • Ohlsson, K.1    Ganrot, P.O.2    Laurell, C.B.3
  • 42
    • 0025822649 scopus 로고
    • The SEC receptor recognizes a pentapeptide neodomain of alpha 1-antitrypsinprotease complexes
    • Joslin G, Fallon RJ, Bullock J, Adams SP, Perlmutter DH. The SEC receptor recognizes a pentapeptide neodomain of alpha 1-antitrypsinprotease complexes. J Biol Chem 1991; 266: 11282-8.
    • (1991) J Biol Chem , vol.266 , pp. 11282-11288
    • Joslin, G.1    Fallon, R.J.2    Bullock, J.3    Adams, S.P.4    Perlmutter, D.H.5
  • 44
    • 0029868041 scopus 로고    scopus 로고
    • 1-antitrypsin-trypsin complexes is mediated by the low density lipoprotein receptor-related protein
    • 1-antitrypsin-trypsin complexes is mediated by the low density lipoprotein receptor-related protein. J Biol Chem 1996; 271: 6523-9.
    • (1996) J Biol Chem , vol.271 , pp. 6523-6529
    • Kounnas, M.Z.1    Church, F.C.2    Argraves, W.S.3    Strickland, D.K.4
  • 45
    • 0028998813 scopus 로고
    • Gp330 on type II pneumocytes mediates endocytosis leading to degradation of pro-urokinase, plasminogen activator inhibitor-1 and urokinase-plasminogen activator inhibitor-1 complex
    • Stefansson S, Kounnas MZ, Henkin J, Mallampalli RK, Chappell DA, Strickland DK, Strickland DK, Argraves WS. Gp330 on type II pneumocytes mediates endocytosis leading to degradation of pro-urokinase, plasminogen activator inhibitor-1 and urokinase-plasminogen activator inhibitor-1 complex. J Cell Sci 1995; 108: 2361-8.
    • (1995) J Cell Sci , vol.108 , pp. 2361-2368
    • Stefansson, S.1    Kounnas, M.Z.2    Henkin, J.3    Mallampalli, R.K.4    Chappell, D.A.5    Strickland, D.K.6    Strickland, D.K.7    Argraves, W.S.8
  • 46
    • 0029113646 scopus 로고
    • Very low density lipoprotein receptor binds and mediates endocytosis of urokinase-type plasminogen activator-type-1 plasminogen activator inhibitor complex
    • Heegaard CW, Simonsen ACW, Oka K, Kjoller L, Christensen A, Madsen B, Ellgaard L, Chan L, Andreasen PA. Very low density lipoprotein receptor binds and mediates endocytosis of urokinase-type plasminogen activator-type-1 plasminogen activator inhibitor complex. J Biol Chem 1995; 270: 20855-61.
    • (1995) J Biol Chem , vol.270 , pp. 20855-20861
    • Heegaard, C.W.1    Simonsen, A.C.W.2    Oka, K.3    Kjoller, L.4    Christensen, A.5    Madsen, B.6    Ellgaard, L.7    Chan, L.8    Andreasen, P.A.9
  • 47
    • 0030886795 scopus 로고    scopus 로고
    • Specificity of serine proteinase/serpin complex binding to very-low-density lipoprotein receptor and alpha2-macroglobulin receptor/low-density-lipoprotein-receptor-related protein
    • Kasza A, Petersen HH, Heegaard CW, Oka K, Christensen A, Dubin A, Chan L, Andreasen PA. Specificity of serine proteinase/serpin complex binding to very-low-density lipoprotein receptor and alpha2-macroglobulin receptor/low-density-lipoprotein-receptor-related protein. Eur J Biochem 1997; 248: 270-81.
    • (1997) Eur J Biochem , vol.248 , pp. 270-281
    • Kasza, A.1    Petersen, H.H.2    Heegaard, C.W.3    Oka, K.4    Christensen, A.5    Dubin, A.6    Chan, L.7    Andreasen, P.A.8
  • 49
    • 0035395799 scopus 로고    scopus 로고
    • Analysis of a two-domain binding site for the urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex in low-density-lipoprotein-receptor-related protein
    • Andersen OM, Petersen HH, Jacobsen C, Moestrup SK, Etzerodt M, Andreasen PA, Thogersen HC. Analysis of a two-domain binding site for the urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex in low-density-lipoprotein-receptor-related protein. Biochem J 2001; 357: 289-96.
    • (2001) Biochem J , vol.357 , pp. 289-296
    • Andersen, O.M.1    Petersen, H.H.2    Jacobsen, C.3    Moestrup, S.K.4    Etzerodt, M.5    Andreasen, P.A.6    Thogersen, H.C.7
  • 50
    • 0029873479 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 and vitronectin promote the cellular clearance of thrombin by low density lipoprotein receptor-related proteins 1 and 2
    • Stefansson S, Lawrence DA, Argraves WS. Plasminogen activator inhibitor-1 and vitronectin promote the cellular clearance of thrombin by low density lipoprotein receptor-related proteins 1 and 2. J Biol Chem 1996; 271: 8215-20.
    • (1996) J Biol Chem , vol.271 , pp. 8215-8220
    • Stefansson, S.1    Lawrence, D.A.2    Argraves, W.S.3
  • 51
    • 0032513248 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 contains a cryptic high affinity binding site for the low density lipoprotein receptor-related protein
    • Stefansson S, Muhammad S, Cheng XF, Battey FD, Strickland DK, Lawrence DA. Plasminogen activator inhibitor-1 contains a cryptic high affinity binding site for the low density lipoprotein receptor-related protein. J Biol Chem 1998; 273: 6358-66.
    • (1998) J Biol Chem , vol.273 , pp. 6358-6366
    • Stefansson, S.1    Muhammad, S.2    Cheng, X.F.3    Battey, F.D.4    Strickland, D.K.5    Lawrence, D.A.6
  • 52
    • 0030716260 scopus 로고    scopus 로고
    • The efficient catabolism of thrombin-protease nexin 1 complexes is a synergistic mechanism that requires both the LDL receptor-related protein and cell surface heparins
    • Knauer MF, Kridel SJ, Hawley SB, Knauer DJ. The efficient catabolism of thrombin-protease nexin 1 complexes is a synergistic mechanism that requires both the LDL receptor-related protein and cell surface heparins. J Biol Chem 1997; 272: 29039-45.
    • (1997) J Biol Chem , vol.272 , pp. 29039-29045
    • Knauer, M.F.1    Kridel, S.J.2    Hawley, S.B.3    Knauer, D.J.4
  • 53
    • 0022393939 scopus 로고
    • Association of thrombin-antithrombin III complex with vitronectin in serum
    • Ill CR, Ruoslahti E. Association of thrombin-antithrombin III complex with vitronectin in serum. J Biol Chem 1985; 260: 15610-5.
    • (1985) J Biol Chem , vol.260 , pp. 15610-15615
    • Ill, C.R.1    Ruoslahti, E.2
  • 54
    • 0027475888 scopus 로고
    • Ternary vitronectin-thrombin-antithrombin III complexes in human plasma Detection and mode of association
    • De Boer HC, De Groot PG, Bouma BN, Preissner KT. Ternary vitronectin-thrombin-antithrombin III complexes in human plasma. Detection and mode of association. J Biol Chem 1993; 268: 1279-83.
    • (1993) J Biol Chem , vol.268 , pp. 1279-1283
    • De Boer, H.C.1    De Groot, P.G.2    Bouma, B.N.3    Preissner, K.T.4
  • 55
    • 0028944244 scopus 로고
    • The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae
    • Stahl A, Mueller BM. The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae. J Cell Biol 1995; 129: 335-44.
    • (1995) J Cell Biol , vol.129 , pp. 335-344
    • Stahl, A.1    Mueller, B.M.2
  • 56
    • 0029294650 scopus 로고
    • The structure and function of the urokinase receptor, a membrane protein governing plasminogen activation on the cell surface
    • Behrendt N, Ronne E, Dano K. The structure and function of the urokinase receptor, a membrane protein governing plasminogen activation on the cell surface. Biol Chem Hoppe Seyler 1995; 376: 269-79.
    • (1995) Biol Chem Hoppe Seyler , vol.376 , pp. 269-279
    • Behrendt, N.1    Ronne, E.2    Dano, K.3
  • 58
    • 0033824172 scopus 로고    scopus 로고
    • Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth
    • Ossowski L, Aguirre-Ghiso JA. Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth. Curr Opin Cell Biol 2000; 12: 613-20.
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 613-620
    • Ossowski, L.1    Aguirre-Ghiso, J.A.2
  • 60
    • 0030990831 scopus 로고    scopus 로고
    • Embryonic fibroblasts that are genetically deficient in low density lipoprotein receptor-related protein demonstrate increased activity of the urokinase receptor system and accelerated migration on vitronectin
    • Weaver AM, Hussaini IM, Mazar A, Henkin J, Gonias SL. Embryonic fibroblasts that are genetically deficient in low density lipoprotein receptor-related protein demonstrate increased activity of the urokinase receptor system and accelerated migration on vitronectin. J Biol Chem 1997; 272: 14372-9.
    • (1997) J Biol Chem , vol.272 , pp. 14372-14379
    • Weaver, A.M.1    Hussaini, I.M.2    Mazar, A.3    Henkin, J.4    Gonias, S.L.5
  • 61
    • 0034705424 scopus 로고    scopus 로고
    • Urokinase-type plasminogen activator stimulates the Ras/Extracellular signal-regulated kinase (ERK) signaling pathway and MCF-7 cell migration by a mechanism that requires focal adhesion kinase Src, and Shc Rapid dissociation of GRB2/Sps-Shc complex is associated with the transient phosphorylation of ERK in urokinase-treated cells
    • Nguyen DH, Webb DJ, Catling AD, Song Q, Dhakephalkar A, Weber MJ, Ravichandran KS, Gonias SL. Urokinase-type plasminogen activator stimulates the Ras/Extracellular signal-regulated kinase (ERK) signaling pathway and MCF-7 cell migration by a mechanism that requires focal adhesion kinase Src, and Shc. Rapid dissociation of GRB2/Sps-Shc complex is associated with the transient phosphorylation of ERK in urokinase-treated cells. J Biol Chem 2000; 275: 19382-8.
    • (2000) J Biol Chem , vol.275 , pp. 19382-19388
    • Nguyen, D.H.1    Webb, D.J.2    Catling, A.D.3    Song, Q.4    Dhakephalkar, A.5    Weber, M.J.6    Ravichandran, K.S.7    Gonias, S.L.8
  • 62
    • 0035911155 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor 1 functions as a urokinase response modifier at the level of cell signaling and thereby promotesMCF-7 cell growth
    • Webb DJ, Thomas KS, Gonias SL. Plasminogen activator inhibitor 1 functions as a urokinase response modifier at the level of cell signaling and thereby promotesMCF-7 cell growth.J CellBiol 2001; 152: 741-52.
    • (2001) J CellBiol , vol.152 , pp. 741-752
    • Webb, D.J.1    Thomas, K.S.2    Gonias, S.L.3
  • 63
    • 0034682827 scopus 로고    scopus 로고
    • Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction
    • Gotthardt M, Trommsdorff M, Nevitt MF, Shelton J, Richardson JA, Stockinger W, Nimpf J, Herz J. Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction. J Biol Chem 2000; 275: 25616-24.
    • (2000) J Biol Chem , vol.275 , pp. 25616-25624
    • Gotthardt, M.1    Trommsdorff, M.2    Nevitt, M.F.3    Shelton, J.4    Richardson, J.A.5    Stockinger, W.6    Nimpf, J.7    Herz, J.8
  • 64
    • 0032509346 scopus 로고    scopus 로고
    • Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein
    • Trommsdorff M, Borg JP, Margolis B, Herz J. Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein. J Biol Chem 1998; 273: 33556-60.
    • (1998) J Biol Chem , vol.273 , pp. 33556-33560
    • Trommsdorff, M.1    Borg, J.P.2    Margolis, B.3    Herz, J.4
  • 65
    • 0037138381 scopus 로고    scopus 로고
    • PTB or not PTB - that is the question
    • Yan KS, Kuti M, Zhou MM. PTB or not PTB - that is the question. FEBS Lett 2002; 513: 67-70.
    • (2002) FEBS Lett , vol.513 , pp. 67-70
    • Yan, K.S.1    Kuti, M.2    Zhou, M.M.3
  • 66
    • 0032776320 scopus 로고    scopus 로고
    • Diversity in protein recognition by PTB domains
    • Forman-Kay JD, Pawson T. Diversity in protein recognition by PTB domains. Curr Opin Struct Biol 1999; 9: 690-5.
    • (1999) Curr Opin Struct Biol , vol.9 , pp. 690-695
    • Forman-Kay, J.D.1    Pawson, T.2
  • 67
    • 0032557542 scopus 로고    scopus 로고
    • Nerve growth factor induces rapid increases in functional cell surface low density lipoprotein receptor-related protein
    • Bu G, Sun Y, Schwartz AL, Holtzman DM. Nerve growth factor induces rapid increases in functional cell surface low density lipoprotein receptor-related protein. J Biol Chem 1998; 273: 13359-65.
    • (1998) J Biol Chem , vol.273 , pp. 13359-13365
    • Bu, G.1    Sun, Y.2    Schwartz, A.L.3    Holtzman, D.M.4
  • 68
    • 0035144390 scopus 로고    scopus 로고
    • Identification of a major cyclic AMP-dependent protein kinase A phosphorylation site within the cytoplasmic tail of the low-density lipoprotein receptorrelated protein: implication for receptor-mediated endocytosis
    • Li Y, van Kerkhof P, Marzolo MP, Strous GJ, Bu G. Identification of a major cyclic AMP-dependent protein kinase A phosphorylation site within the cytoplasmic tail of the low-density lipoprotein receptorrelated protein: implication for receptor-mediated endocytosis. Mol Cell Biol 2001; 21: 1185-95.
    • (2001) Mol Cell Biol , vol.21 , pp. 1185-1195
    • Li, Y.1    van Kerkhof, P.2    Marzolo, M.P.3    Strous, G.J.4    Bu, G.5
  • 69
    • 0035374620 scopus 로고    scopus 로고
    • Tyrosine phosphorylated LDL receptor-related protein 1 (LRP1) associates with the adaptor protein Shc in Src-transformed cells
    • Barnes H, Larsen B, Tyers M, van Der GP. Tyrosine phosphorylated LDL receptor-related protein 1 (LRP1) associates with the adaptor protein Shc in Src-transformed cells. J Biol Chem 2001; 22: 19119-25.
    • (2001) J Biol Chem , vol.22 , pp. 19119-19125
    • Barnes, H.1    Larsen, B.2    Tyers, M.3    van Der, G.P.4
  • 71
    • 18544378303 scopus 로고    scopus 로고
    • Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP) Evidence for integrated co-receptor function between LRP and the PDGF
    • Loukinova E, Ranganathan S, Kuznetsov S, Gorlatova N, Migliorini MM, Loukinov D, Ulery PG, Mikhailenko I, Lawrence DA, Strickland DK. Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP). Evidence for integrated co-receptor function between LRP and the PDGF. J Biol Chem 2002; 277: 15499-506.
    • (2002) J Biol Chem , vol.277 , pp. 15499-15506
    • Loukinova, E.1    Ranganathan, S.2    Kuznetsov, S.3    Gorlatova, N.4    Migliorini, M.M.5    Loukinov, D.6    Ulery, P.G.7    Mikhailenko, I.8    Lawrence, D.A.9    Strickland, D.K.10
  • 73
    • 0026678172 scopus 로고
    • Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases
    • Rozakis-Adcock M, McGlade J, Mbamalu G, Pelicci G, Daly R, Li W, Batzer A, Thomas S, Brugge J, Pelicci PG et al. Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. Nature 1992; 360 (6405): 689-92.
    • (1992) Nature , vol.360 , Issue.6405 , pp. 689-692
    • Rozakis-Adcock, M.1    McGlade, J.2    Mbamalu, G.3    Pelicci, G.4    Daly, R.5    Li, W.6    Batzer, A.7    Thomas, S.8    Brugge, J.9    Pelicci, P.G.10
  • 74
    • 0030899807 scopus 로고    scopus 로고
    • Tyrosine phosphorylation sites at amino acids 239 and 240 of Shc are involved in epidermal growth factorinduced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activation
    • Gotoh N, Toyoda M, Shibuya M. Tyrosine phosphorylation sites at amino acids 239 and 240 of Shc are involved in epidermal growth factorinduced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activation. Mol Cell Biol 1997; 17: 1824-31.
    • (1997) Mol Cell Biol , vol.17 , pp. 1824-1831
    • Gotoh, N.1    Toyoda, M.2    Shibuya, M.3
  • 75
    • 0037013188 scopus 로고    scopus 로고
    • Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low density lipoprotein receptor-related protein in caveolae
    • Boucher P, Liu P, Gotthardt M, Hiesberger T, Anderson RG, Herz J. Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low density lipoprotein receptor-related protein in caveolae. J Biol Chem 2002; 277: 15507-13.
    • (2002) J Biol Chem , vol.277 , pp. 15507-15513
    • Boucher, P.1    Liu, P.2    Gotthardt, M.3    Hiesberger, T.4    Anderson, R.G.5    Herz, J.6
  • 76
    • 0029879507 scopus 로고    scopus 로고
    • Localization of platelet-derived growth factor-stimulated phosphorylation cascade to caveolae
    • Liu P, Ying Y, Ko YG, Anderson RG. Localization of platelet-derived growth factor-stimulated phosphorylation cascade to caveolae. J Biol Chem 1996; 271: 10299-303.
    • (1996) J Biol Chem , vol.271 , pp. 10299-10303
    • Liu, P.1    Ying, Y.2    Ko, Y.G.3    Anderson, R.G.4
  • 77
    • 0037036135 scopus 로고    scopus 로고
    • A role for lipid shells in targeting proteins to caveolae, rafts,andother lipiddomains
    • Anderson RG, Jacobson K. A role for lipid shells in targeting proteins to caveolae, rafts,andother lipiddomains.Science2002;296(5574):1821-5.
    • (2002) Science , vol.296 , Issue.5574 , pp. 1821-1825
    • Anderson, R.G.1    Jacobson, K.2
  • 78
    • 0032875460 scopus 로고    scopus 로고
    • Mechanism of action and in vivo role of platelet-derived growth factor
    • Heldin CH, Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 1999; 79: 1283-316.
    • (1999) Physiol Rev , vol.79 , pp. 1283-1316
    • Heldin, C.H.1    Westermark, B.2
  • 79
    • 0029799088 scopus 로고    scopus 로고
    • Contrasting effects of plasminogen activators, urokinase receptor, and LDL receptor-related protein on smooth muscle cell migration and invasion
    • Okada SS, Grobmyer SR, Barnathan ES. Contrasting effects of plasminogen activators, urokinase receptor, and LDL receptor-related protein on smooth muscle cell migration and invasion. Arterioscler Thromb Vasc Biol 1996; 16: 1269-76.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1269-1276
    • Okada, S.S.1    Grobmyer, S.R.2    Barnathan, E.S.3
  • 80
    • 0032493648 scopus 로고    scopus 로고
    • Apolipoprotein E inhibits platelet-derived growth factor-induced vascular smooth muscle cell migration and proliferation by suppressing signal transduction and preventing cell entry to G1 phase
    • Ishigami M, Swertfeger DK, Granholm NA, Hui DY, Apolipoprotein E inhibits platelet-derived growth factor-induced vascular smooth muscle cell migration and proliferation by suppressing signal transduction and preventing cell entry to G1 phase. J Biol Chem 1998; 273: 20156-61.
    • (1998) J Biol Chem , vol.273 , pp. 20156-20161
    • Ishigami, M.1    Swertfeger, D.K.2    Granholm, N.A.3    Hui, D.Y.4
  • 81
    • 0037040224 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-related protein mediates apolipoprotein E inhibition of smooth muscle cell migration
    • Swertfeger DK, Bu G, Hui DY. Low density lipoprotein receptor-related protein mediates apolipoprotein E inhibition of smooth muscle cell migration. J Biol Chem 2002; 277: 4141-6.
    • (2002) J Biol Chem , vol.277 , pp. 4141-4146
    • Swertfeger, D.K.1    Bu, G.2    Hui, D.Y.3
  • 82
  • 83
    • 0033568616 scopus 로고    scopus 로고
    • Characterization of the soluble form of the low density lipoprotein receptorrelated protein (LRP)
    • Quinn KA, Pye VJ, Dai YP, Chesterman CN, Owensby DA. Characterization of the soluble form of the low density lipoprotein receptorrelated protein (LRP). Exp Cell Res 1999; 251: 433-41.
    • (1999) Exp Cell Res , vol.251 , pp. 433-441
    • Quinn, K.A.1    Pye, V.J.2    Dai, Y.P.3    Chesterman, C.N.4    Owensby, D.A.5
  • 84
    • 0037166319 scopus 로고    scopus 로고
    • Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain
    • May P, Reddy YK, Herz J. Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain. J Biol Chem 2002; 277: 18736-43.
    • (2002) J Biol Chem , vol.277 , pp. 18736-18743
    • May, P.1    Reddy, Y.K.2    Herz, J.3
  • 89
    • 0034681260 scopus 로고    scopus 로고
    • Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans
    • Brown MS, Ye J, Rawson RB, Goldstein JL. Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell 2000; 100: 391-8.
    • (2000) Cell , vol.100 , pp. 391-398
    • Brown, M.S.1    Ye, J.2    Rawson, R.B.3    Goldstein, J.L.4
  • 90
    • 0035824391 scopus 로고    scopus 로고
    • Carpenter G. gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase
    • Ni CY, Murphy MP, Golde TE, Carpenter G. gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase. Science 2001; 294 (5549): 2179-81.
    • (2001) Science , vol.294 , Issue.5549 , pp. 2179-2181
    • Ni, C.Y.1    Murphy, M.P.2    Golde, T.E.3
  • 94
    • 0035912890 scopus 로고    scopus 로고
    • Functional blockade of plateletderived growth factor receptor-beta but not of receptor-alpha prevents vascular smooth muscle cell accumulation in fibrous cap lesions in apolipoprotein E-deficient mice
    • Sano H, Sudo T, Yokode M, Murayama T, Kataoka H, Takakura N, Nishikawa S, Nishikawa SI, Kita T. Functional blockade of plateletderived growth factor receptor-beta but not of receptor-alpha prevents vascular smooth muscle cell accumulation in fibrous cap lesions in apolipoprotein E-deficient mice. Circulation 2001; 103: 2955-60.
    • (2001) Circulation , vol.103 , pp. 2955-2960
    • Sano, H.1    Sudo, T.2    Yokode, M.3    Murayama, T.4    Kataoka, H.5    Takakura, N.6    Nishikawa, S.7    Nishikawa, S.I.8    Kita, T.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.