-
1
-
-
0033677809
-
C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease
-
A. Abraha, N. Ghoshal, T.C. Gamblin, V. Cryns, R.W. Berry, J. Kuret and L.I. Binder, C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease, J Cell Sci 113(Pt 21) (2000), 3737-3745.
-
(2000)
J Cell Sci
, vol.113
, Issue.PART 21
, pp. 3737-3745
-
-
Abraha, A.1
Ghoshal, N.2
Gamblin, T.C.3
Cryns, V.4
Berry, R.W.5
Kuret, J.6
Binder, L.I.7
-
2
-
-
0036850725
-
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein
-
B. Allen, E. Ingram, M. Takao, M.J. Smith, R. Jakes, K. Virdee, H. Yoshida, M. Holzer, M. Craxton, P.C. Emson, C. Atzori, A. Migheli, R.A. Crowther, B. Ghetti, M.G. Spillantini and M. Goedert, Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein, J Neurosci 22 (2002), 9340-9351.
-
(2002)
J Neurosci
, vol.22
, pp. 9340-9351
-
-
Allen, B.1
Ingram, E.2
Takao, M.3
Smith, M.J.4
Jakes, R.5
Virdee, K.6
Yoshida, H.7
Holzer, M.8
Craxton, M.9
Emson, P.C.10
Atzori, C.11
Migheli, A.12
Crowther, R.A.13
Ghetti, B.14
Spillantini, M.G.15
Goedert, M.16
-
3
-
-
33745024475
-
Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity
-
C. Alonso Adel, B. Li, I. Grundke-Iqbal and K. Iqbal, Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity, Proc Natl Acad Sci USA 103 (2006), 8864-8869.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 8864-8869
-
-
Alonso Adel, C.1
Li, B.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
4
-
-
0028856460
-
An English translation of Alzheimer's 1907 paper, "Uber eine eigenartige Erkankung der Hirnrinde
-
A. Alzheimer, R.A. Stelzmann, H.N. Schnitzlein and F.R. Murtagh, An English translation of Alzheimer's 1907 paper, "Uber eine eigenartige Erkankung der Hirnrinde", Clin Anat 8 (1995), 429-431.
-
(1995)
Clin Anat
, vol.8
, pp. 429-431
-
-
Alzheimer, A.1
Stelzmann, R.A.2
Schnitzlein, H.N.3
Murtagh, F.R.4
-
5
-
-
0026743110
-
Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease
-
P.V. Arriagada, K. Marzloff and B.T. Hyman, Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease, Neurology 42 (1992), 1681-1688.
-
(1992)
Neurology
, vol.42
, pp. 1681-1688
-
-
Arriagada, P.V.1
Marzloff, K.2
Hyman, B.T.3
-
6
-
-
22144484862
-
Assembly in vitro of tau protein and its implications in Alzheimer's disease
-
J. Avila, M. Perez, J.J. Lucas, A. Gomez-Ramos, I. Santa Maria, F. Moreno, M. Smith, G. Perry and F. Hernandez, Assembly in vitro of tau protein and its implications in Alzheimer's disease, Curr Alzheimer Res 1 (2004), 97-101.
-
(2004)
Curr Alzheimer Res
, vol.1
, pp. 97-101
-
-
Avila, J.1
Perez, M.2
Lucas, J.J.3
Gomez-Ramos, A.4
Santa Maria, I.5
Moreno, F.6
Smith, M.7
Perry, G.8
Hernandez, F.9
-
7
-
-
33745140951
-
Tau phosphorylation and aggregation in Alzheimer's disease pathology
-
J. Avila, Tau phosphorylation and aggregation in Alzheimer's disease pathology, FEBS Lett 580 (2006), 2922-2927.
-
(2006)
FEBS Lett
, vol.580
, pp. 2922-2927
-
-
Avila, J.1
-
8
-
-
0024587074
-
Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease
-
C. Bancher, C. Brunner, H. Lassmann, H. Budka, K. Jellinger, G. Wiche, F. Seitelberger, I. Grundke-Iqbal, K. Iqbal and H.M. Wisniewski, Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease, Brain Res 477 (1989), 90-99.
-
(1989)
Brain Res
, vol.477
, pp. 90-99
-
-
Bancher, C.1
Brunner, C.2
Lassmann, H.3
Budka, H.4
Jellinger, K.5
Wiche, G.6
Seitelberger, F.7
Grundke-Iqbal, I.8
Iqbal, K.9
Wisniewski, H.M.10
-
9
-
-
34447498400
-
Tau aggregation and toxicity in a cell culture model of tauopathy
-
B. Bandyopadhyay, G. Li, H. Yin and J. Kuret, Tau aggregation and toxicity in a cell culture model of tauopathy, J Biol Chem 282 (2007), 16454-16464.
-
(2007)
J Biol Chem
, vol.282
, pp. 16454-16464
-
-
Bandyopadhyay, B.1
Li, G.2
Yin, H.3
Kuret, J.4
-
10
-
-
43249129441
-
Accumulation of aspartic acid421- and glutamic acid391-cleaved tau in neurofibrillary tangles correlates with progression in Alzheimer disease
-
G. Basurto-Islas, J. Luna-Muñoz, A.L. Guillozet-Bongaarts, L.I. Binder, R. Mena and F. García-Sierra, Accumulation of aspartic acid421- and glutamic acid391-cleaved tau in neurofibrillary tangles correlates with progression in Alzheimer disease, J Neuropathol Exp Neurol 67 (2008), 470-483.
-
(2008)
J Neuropathol Exp Neurol
, vol.67
, pp. 470-483
-
-
Basurto-Islas, G.1
Luna-Muñoz, J.2
Guillozet-Bongaarts, A.L.3
Binder, L.I.4
Mena, R.5
García-Sierra, F.6
-
11
-
-
0037826853
-
Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment
-
R.W. Berry, A. Abraha, S. Lagalwar, N. LaPointe, T.C. Gamblin, V.L. Cryns and L.I. Binder, Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment, Biochemistry 42 (2003), 8325-8331.
-
(2003)
Biochemistry
, vol.42
, pp. 8325-8331
-
-
Berry, R.W.1
Abraha, A.2
Lagalwar, S.3
LaPointe, N.4
Gamblin, T.C.5
Cryns, V.L.6
Binder, L.I.7
-
12
-
-
0028861585
-
Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease
-
L.M. Bierer, P.R. Hof, D.P. Purohit, L. Carlin, J. Schmeidler, K.L. Davis and D.P. Perl, Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease, Arch Neurol 52 (1995), 81-88.
-
(1995)
Arch Neurol
, vol.52
, pp. 81-88
-
-
Bierer, L.M.1
Hof, P.R.2
Purohit, D.P.3
Carlin, L.4
Schmeidler, J.5
Davis, K.L.6
Perl, D.P.7
-
13
-
-
0026551711
-
The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region
-
J. Biernat, E.M. Mandelkow, C. Schroter, B. Lichtenberg-Kraag, B. Steiner, B. Berling, H. Meyer, M. Mercken, A. Vandermeeren, M. Goedert et al., The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region, Embo J 11 (1992), 1593-1597.
-
(1992)
Embo J
, vol.11
, pp. 1593-1597
-
-
Biernat, J.1
Mandelkow, E.M.2
Schroter, C.3
Lichtenberg-Kraag, B.4
Steiner, B.5
Berling, B.6
Meyer, H.7
Mercken, M.8
Vandermeeren, A.9
Goedert, M.10
-
14
-
-
10944248857
-
Tau, tangles, and Alzheimer's disease
-
L.I. Binder, A.L. Guillozet-Bongaarts, F. Garcia-Sierra and R.W. Berry, Tau, tangles, and Alzheimer's disease, Biochim Biophys Acta 1739 (2005), 216-223.
-
(2005)
Biochim Biophys Acta
, vol.1739
, pp. 216-223
-
-
Binder, L.I.1
Guillozet-Bongaarts, A.L.2
Garcia-Sierra, F.3
Berry, R.W.4
-
15
-
-
42449091462
-
Small heat shock proteins Hsp27 or alphaB-crystallin and the protein components of neurofibrillary tangles: Tau and neurofilaments
-
C. Bjorkdahl, M.J. Sjogren, X. Zhou, H. Concha, J. Avila, B. Winblad and J.J. Pei, Small heat shock proteins Hsp27 or alphaB-crystallin and the protein components of neurofibrillary tangles: Tau and neurofilaments, J Neurosci Res 86 (2007), 1343-1352.
-
(2007)
J Neurosci Res
, vol.86
, pp. 1343-1352
-
-
Bjorkdahl, C.1
Sjogren, M.J.2
Zhou, X.3
Concha, H.4
Avila, J.5
Winblad, B.6
Pei, J.J.7
-
16
-
-
0028345718
-
Immunohistochemical staging of neurofibrillary degeneration in Alzheimer's disease
-
W. Bondareff, C. Harrington, C.M. Wischik, D.L. Hauser and M. Roth, Immunohistochemical staging of neurofibrillary degeneration in Alzheimer's disease, J Neuropathol Exp Neurol 53 (1994), 158-164.
-
(1994)
J Neuropathol Exp Neurol
, vol.53
, pp. 158-164
-
-
Bondareff, W.1
Harrington, C.2
Wischik, C.M.3
Hauser, D.L.4
Roth, M.5
-
17
-
-
0022595501
-
Occurrence of neuropil threads in the senile human brain and in Alzheimer's disease: A third location of paired helical filaments outside of neurofibrillary tangles and neuritic plaques
-
H. Braak, E. Braak, I. Grundke-Iqbal and K. Iqbal, Occurrence of neuropil threads in the senile human brain and in Alzheimer's disease: a third location of paired helical filaments outside of neurofibrillary tangles and neuritic plaques, Neurosci Lett 65 (1986), 351-355.
-
(1986)
Neurosci Lett
, vol.65
, pp. 351-355
-
-
Braak, H.1
Braak, E.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
18
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
H. Braak and E. Braak, Neuropathological stageing of Alzheimer-related changes, Acta Neuropathol (Berl) 82 (1991), 239-259.
-
(1991)
Acta Neuropathol (Berl)
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
19
-
-
17344365975
-
Tau cleavage and dephosphorylation in cerebellar granule neurons undergoing apoptosis
-
N. Canu, L. Dus, C. Barbato, M.T. Ciotti, C. Brancolini, A.M. Rinaldi, M. Novak, A. Cattaneo, A. Bradbury and P. Calissano, Tau cleavage and dephosphorylation in cerebellar granule neurons undergoing apoptosis, J Neurosci 18 (1998), 7061-7074.
-
(1998)
J Neurosci
, vol.18
, pp. 7061-7074
-
-
Canu, N.1
Dus, L.2
Barbato, C.3
Ciotti, M.T.4
Brancolini, C.5
Rinaldi, A.M.6
Novak, M.7
Cattaneo, A.8
Bradbury, A.9
Calissano, P.10
-
20
-
-
12644260802
-
The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology
-
G. Carmel, E.M. Mager, L.I. Binder and J. Kuret, The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology, J Biol Chem 271 (1996), 32789-32795.
-
(1996)
J Biol Chem
, vol.271
, pp. 32789-32795
-
-
Carmel, G.1
Mager, E.M.2
Binder, L.I.3
Kuret, J.4
-
21
-
-
39149131025
-
Platelet as a physiological model to investigate apoptotic mechanisms in Alzheimer beta-amyloid peptide production
-
T. Casoli, G. Di Stefano, B. Giorgetti, M. Balietti, R. Recchioni, F. Moroni, F. Marcheselli, G. Bernardini, P. Fattoretti and C. Bertoni-Freddari, Platelet as a physiological model to investigate apoptotic mechanisms in Alzheimer beta-amyloid peptide production, Mech Ageing Dev 129 (2008), 154-162.
-
(2008)
Mech Ageing Dev
, vol.129
, pp. 154-162
-
-
Casoli, T.1
Di Stefano, G.2
Giorgetti, B.3
Balietti, M.4
Recchioni, R.5
Moroni, F.6
Marcheselli, F.7
Bernardini, G.8
Fattoretti, P.9
Bertoni-Freddari, C.10
-
22
-
-
34548162377
-
Activation of glycogen synthase kinase 3beta promotes the intermolecular association of tau. The use of fluorescence resonance energy transfer microscopy
-
W. Chun and G.V. Johnson, Activation of glycogen synthase kinase 3beta promotes the intermolecular association of tau. The use of fluorescence resonance energy transfer microscopy, J Biol Chem 282 (2007), 23410-23417.
-
(2007)
J Biol Chem
, vol.282
, pp. 23410-23417
-
-
Chun, W.1
Johnson, G.V.2
-
23
-
-
0035116325
-
Proapoptotic effects of tau cleavage product generated by caspase-3
-
C.W. Chung, Y.H. Song, I.K. Kim, W.J. Yoon, B.R. Ryu, D.G. Jo, H.N. Woo, Y.K. Kwon, H.H. Kim, B.J. Gwag, I.H. Mook-Jung and Y.K. Jung, Proapoptotic effects of tau cleavage product generated by caspase-3, Neurobiol Dis 8 (2001), 162-172.
-
(2001)
Neurobiol Dis
, vol.8
, pp. 162-172
-
-
Chung, C.W.1
Song, Y.H.2
Kim, I.K.3
Yoon, W.J.4
Ryu, B.R.5
Jo, D.G.6
Woo, H.N.7
Kwon, Y.K.8
Kim, H.H.9
Gwag, B.J.10
Mook-Jung, I.H.11
Jung, Y.K.12
-
24
-
-
14844328111
-
The role of caspase cleavage of tau in Alzheimer disease neuropathology
-
C.W. Cotman, W.W. Poon, R.A. Rissman and M. Blurton-Jones, The role of caspase cleavage of tau in Alzheimer disease neuropathology, J Neuropathol Exp Neurol 64 (2005), 104-112.
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, pp. 104-112
-
-
Cotman, C.W.1
Poon, W.W.2
Rissman, R.A.3
Blurton-Jones, M.4
-
25
-
-
38749144389
-
Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy
-
P. Delobel, I. Lavenir, G. Fraser, E. Ingram, M. Holzer, B. Ghetti, M.G. Spillantini, R.A. Crowther and M. Goedert, Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy, Am J Pathol 172 (2008), 123-131.
-
(2008)
Am J Pathol
, vol.172
, pp. 123-131
-
-
Delobel, P.1
Lavenir, I.2
Fraser, G.3
Ingram, E.4
Holzer, M.5
Ghetti, B.6
Spillantini, M.G.7
Crowther, R.A.8
Goedert, M.9
-
26
-
-
0029078972
-
Correlations of synaptic and pathological markers with cognition of the elderly
-
discussion 298-304
-
D.W. Dickson, H.A. Crystal, C. Bevona, W. Honer, I. Vincent and P. Davies, Correlations of synaptic and pathological markers with cognition of the elderly, Neurobiol Aging 16 (1995), 285-298; discussion 298-304.
-
(1995)
Neurobiol Aging
, vol.16
, pp. 285-298
-
-
Dickson, D.W.1
Crystal, H.A.2
Bevona, C.3
Honer, W.4
Vincent, I.5
Davies, P.6
-
27
-
-
85047693458
-
Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: Cause or effect?
-
D.W. Dickson, Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: cause or effect? J Clin Invest 114 (2004), 23-27.
-
(2004)
J Clin Invest
, vol.114
, pp. 23-27
-
-
Dickson, D.W.1
-
28
-
-
0032476645
-
Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: Implications for Alzheimer's disease
-
A. Ebneth, R. Godemann, K. Stamer, S. Illenberger, B. Trinczek and E. Mandelkow, Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease, J Cell Biol 143 (1998), 777-794.
-
(1998)
J Cell Biol
, vol.143
, pp. 777-794
-
-
Ebneth, A.1
Godemann, R.2
Stamer, K.3
Illenberger, S.4
Trinczek, B.5
Mandelkow, E.6
-
29
-
-
33646922314
-
Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3
-
T. Engel, F. Hernandez, J. Avila and J.J. Lucas, Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3, J Neurosci 26 (2006), 5083-5090.
-
(2006)
J Neurosci
, vol.26
, pp. 5083-5090
-
-
Engel, T.1
Hernandez, F.2
Avila, J.3
Lucas, J.J.4
-
30
-
-
33746210131
-
Cooexpression of FTDP-17 tau and GSK-3beta in transgenic mice induce tau polymerization and neurodegeneration
-
T. Engel, J.J. Lucas, P. Gomez-Ramos, M.A. Moran, J. Avila and F. Hernandez, Cooexpression of FTDP-17 tau and GSK-3beta in transgenic mice induce tau polymerization and neurodegeneration, Neurobiol Aging 27 (2006), 1258-1268.
-
(2006)
Neurobiol Aging
, vol.27
, pp. 1258-1268
-
-
Engel, T.1
Lucas, J.J.2
Gomez-Ramos, P.3
Moran, M.A.4
Avila, J.5
Hernandez, F.6
-
31
-
-
0141648356
-
Subicular dendritic arborization in Alzheimer's disease correlates with neurofibrillary tangle density
-
E. Falke, J. Nissanov, T.W. Mitchell, D.A. Bennett, J.Q. Trojanowski and S.E. Arnold, Subicular dendritic arborization in Alzheimer's disease correlates with neurofibrillary tangle density, Am J Pathol 163 (2003), 1615-1621.
-
(2003)
Am J Pathol
, vol.163
, pp. 1615-1621
-
-
Falke, E.1
Nissanov, J.2
Mitchell, T.W.3
Bennett, D.A.4
Trojanowski, J.Q.5
Arnold, S.E.6
-
32
-
-
0030463704
-
implications for the tau truncation hypothesis
-
Overexpression of Alzheimer's PHF core tau fragments
-
L. Fasulo, M. Ovecka, J. Kabat, A. Bradbury, M. Novak and A. Cattaneo, Overexpression of Alzheimer's PHF core tau fragments : implications for the tau truncation hypothesis., Alzheimers Res. 2 (1996), 195-200.
-
(1996)
Alzheimers Res
, vol.2
, pp. 195-200
-
-
Fasulo, L.1
Ovecka, M.2
Kabat, J.3
Bradbury, A.4
Novak, M.5
Cattaneo, A.6
-
33
-
-
22044447582
-
Tau truncation in Alzheimer's disease : Expression of a fragment encompassing PHF core tau induces apoptosis in COS cells
-
L. Fasulo, M. Visintin, M. Novak and A. Cattaneo, Tau truncation in Alzheimer's disease : expression of a fragment encompassing PHF core tau induces apoptosis in COS cells, Alzheimer's Rep. 1 (1998), 25-32.
-
(1998)
Alzheimer's Rep
, vol.1
, pp. 25-32
-
-
Fasulo, L.1
Visintin, M.2
Novak, M.3
Cattaneo, A.4
-
34
-
-
0033928035
-
The neuronal microtubule-associated protein tau is a substrate for caspase-3 and an effector of apoptosis
-
L. Fasulo, G. Ugolini, M. Visintin, A. Bradbury, C. Brancolini, V. Verzillo, M. Novak and A. Cattaneo, The neuronal microtubule-associated protein tau is a substrate for caspase-3 and an effector of apoptosis, J Neurochem 75 (2000), 624-633.
-
(2000)
J Neurochem
, vol.75
, pp. 624-633
-
-
Fasulo, L.1
Ugolini, G.2
Visintin, M.3
Bradbury, A.4
Brancolini, C.5
Verzillo, V.6
Novak, M.7
Cattaneo, A.8
-
35
-
-
0141960033
-
beta-Amyloid induces paired helical filament-like tau filaments in tissue culture
-
A. Ferrari, F. Hoerndli, T. Baechi, R.M. Nitsch and J. Gotz, beta-Amyloid induces paired helical filament-like tau filaments in tissue culture, J Biol Chem 278 (2003), 40162-40168.
-
(2003)
J Biol Chem
, vol.278
, pp. 40162-40168
-
-
Ferrari, A.1
Hoerndli, F.2
Baechi, T.3
Nitsch, R.M.4
Gotz, J.5
-
36
-
-
0026284086
-
Alzheimer dementia. A clinical long-term study with quantitative neuropathology]
-
P. Fischer, H. Lassmann, K. Jellinger, M. Simanyi, C. Bancher, A. Travniczek-Marterer, G. Gatterer and W. Danielczyk, [Alzheimer dementia. A clinical long-term study with quantitative neuropathology], Wien Med Wochenschr 141 (1991), 455-462.
-
(1991)
Wien Med Wochenschr
, vol.141
, pp. 455-462
-
-
Fischer, P.1
Lassmann, H.2
Jellinger, K.3
Simanyi, M.4
Bancher, C.5
Travniczek-Marterer, A.6
Gatterer, G.7
Danielczyk, W.8
-
37
-
-
14844311246
-
Tau phosphorylation increases in symptomatic mice overexpressing A30P alphasynuclein
-
M. Frasier, M. Walzer, L. McCarthy, D. Magnuson, J.M. Lee, C. Haas, P. Kahle and B. Wolozin, Tau phosphorylation increases in symptomatic mice overexpressing A30P alphasynuclein, Exp Neurol 192 (2005), 274-287.
-
(2005)
Exp Neurol
, vol.192
, pp. 274-287
-
-
Frasier, M.1
Walzer, M.2
McCarthy, L.3
Magnuson, D.4
Lee, J.M.5
Haas, C.6
Kahle, P.7
Wolozin, B.8
-
38
-
-
33947286683
-
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo
-
T.A. Fulga, I. Elson-Schwab, V. Khurana, M.L. Steinhilb, T.L. Spires, B.T. Hyman and M.B. Feany, Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo, Nat Cell Biol 9 (2007), 139-148.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 139-148
-
-
Fulga, T.A.1
Elson-Schwab, I.2
Khurana, V.3
Steinhilb, M.L.4
Spires, T.L.5
Hyman, B.T.6
Feany, M.B.7
-
39
-
-
0037465354
-
Tau polymerization: Role of the amino terminus
-
T.C. Gamblin, R.W. Berry and L.I. Binder, Tau polymerization: role of the amino terminus, Biochemistry 42 (2003), 2252-2257.
-
(2003)
Biochemistry
, vol.42
, pp. 2252-2257
-
-
Gamblin, T.C.1
Berry, R.W.2
Binder, L.I.3
-
40
-
-
0041689948
-
Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease
-
T.C. Gamblin, F. Chen, A. Zambrano, A. Abraha, S. Lagalwar, A.L. Guillozet, M. Lu, Y. Fu, F. Garcia-Sierra, N. La-Pointe, R. Miller, R.W. Berry, L.I. Binder and V.L. Cryns, Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease, Proc Natl Acad Sci U S A 100 (2003), 10032-10037.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 10032-10037
-
-
Gamblin, T.C.1
Chen, F.2
Zambrano, A.3
Abraha, A.4
Lagalwar, S.5
Guillozet, A.L.6
Lu, M.7
Fu, Y.8
Garcia-Sierra, F.9
La-Pointe, N.10
Miller, R.11
Berry, R.W.12
Binder, L.I.13
Cryns, V.L.14
-
41
-
-
0342368728
-
The extent of neurofibrillary pathology in perforant pathway neurons is the key determinant of dementia in the very old
-
F. Garcia-Sierra, J.J. Hauw, C. Duyckaerts, C.M. Wischik, J. Luna-Munoz and R. Mena, The extent of neurofibrillary pathology in perforant pathway neurons is the key determinant of dementia in the very old, Acta Neuropathol (Berl) 100 (2000), 29-35.
-
(2000)
Acta Neuropathol (Berl)
, vol.100
, pp. 29-35
-
-
Garcia-Sierra, F.1
Hauw, J.J.2
Duyckaerts, C.3
Wischik, C.M.4
Luna-Munoz, J.5
Mena, R.6
-
42
-
-
0034929144
-
Accumulation of C-terminally truncated tau protein associated with vulnerability of the perforant pathway in early stages of neurofibrillary pathology in Alzheimer's disease
-
F. Garcia-Sierra, C.M. Wischik, C.R. Harrington, J. Luna-Munoz and R. Mena, Accumulation of C-terminally truncated tau protein associated with vulnerability of the perforant pathway in early stages of neurofibrillary pathology in Alzheimer's disease, J Chem Neuroanat 22 (2001), 65-77.
-
(2001)
J Chem Neuroanat
, vol.22
, pp. 65-77
-
-
Garcia-Sierra, F.1
Wischik, C.M.2
Harrington, C.R.3
Luna-Munoz, J.4
Mena, R.5
-
43
-
-
0038291981
-
Conformational changes and truncation of tau protein during tangle evolution in Alzheimer's disease
-
F. Garcia-Sierra, N. Ghoshal, B. Quinn, R.W. Berry and L.I. Binder, Conformational changes and truncation of tau protein during tangle evolution in Alzheimer's disease, J. Alzheimers Dis. 5 (2003), 65-77.
-
(2003)
J. Alzheimers Dis
, vol.5
, pp. 65-77
-
-
Garcia-Sierra, F.1
Ghoshal, N.2
Quinn, B.3
Berry, R.W.4
Binder, L.I.5
-
44
-
-
49149124365
-
Tau protein expressed in COS-7 cells displays similar phosphorylation and conformational changes as it occurs in Alzheimer's disease brains
-
F. Garcia-Sierra, G. Basurto-Islas, I. Santa-Maria, R. Mena, J. Luna-Muñoz and L.I. Binder, Tau protein expressed in COS-7 cells displays similar phosphorylation and conformational changes as it occurs in Alzheimer's disease brains, FENS Forum (2008).
-
(2008)
FENS Forum
-
-
Garcia-Sierra, F.1
Basurto-Islas, G.2
Santa-Maria, I.3
Mena, R.4
Luna-Muñoz, J.5
Binder, L.I.6
-
45
-
-
0042837889
-
Caspase activation in the limbic cortex of subjects with early Alzheimer's disease
-
M.C. Gastard, J.C. Troncoso and V.E. Koliatsos, Caspase activation in the limbic cortex of subjects with early Alzheimer's disease, Ann Neurol 54 (2003), 393-398.
-
(2003)
Ann Neurol
, vol.54
, pp. 393-398
-
-
Gastard, M.C.1
Troncoso, J.C.2
Koliatsos, V.E.3
-
46
-
-
0033617402
-
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation
-
F.G. Gervais, D. Xu, G.S. Robertson, J.P. Vaillancourt, Y. Zhu, J. Huang, A. LeBlanc, D. Smith, M. Rigby, M.S. Shearman, E.E. Clarke, H. Zheng, L.H. Van Der Ploeg, S.C. Ruffolo, N.A. Thornberry, S. Xanthoudakis, R.J. Zamboni, S. Roy and D.W. Nicholson, Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation, Cell 97 (1999), 395-406.
-
(1999)
Cell
, vol.97
, pp. 395-406
-
-
Gervais, F.G.1
Xu, D.2
Robertson, G.S.3
Vaillancourt, J.P.4
Zhu, Y.5
Huang, J.6
LeBlanc, A.7
Smith, D.8
Rigby, M.9
Shearman, M.S.10
Clarke, E.E.11
Zheng, H.12
Van Der Ploeg, L.H.13
Ruffolo, S.C.14
Thornberry, N.A.15
Xanthoudakis, S.16
Zamboni, R.J.17
Roy, S.18
Nicholson, D.W.19
-
47
-
-
0035011587
-
Tau-66: Evidence for a novel tau conformation in Alzheimer's disease
-
N. Ghoshal, F. Garcia-Sierra, Y. Fu, L.A. Beckett, E.J. Mufson, J. Kuret, R.W. Berry and L.I. Binder, Tau-66: evidence for a novel tau conformation in Alzheimer's disease, J Neurochem 77 (2001), 1372-1385.
-
(2001)
J Neurochem
, vol.77
, pp. 1372-1385
-
-
Ghoshal, N.1
Garcia-Sierra, F.2
Fu, Y.3
Beckett, L.A.4
Mufson, E.J.5
Kuret, J.6
Berry, R.W.7
Binder, L.I.8
-
48
-
-
33344463679
-
Common mechanisms of amyloid oligomer pathogenesis in degenerative disease
-
C.G. Glabe, Common mechanisms of amyloid oligomer pathogenesis in degenerative disease, Neurobiol Aging 27 (2006), 570-575.
-
(2006)
Neurobiol Aging
, vol.27
, pp. 570-575
-
-
Glabe, C.G.1
-
49
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
-
I. Grundke-Iqbal, K. Iqbal, Y.C. Tung, M. Quinlan, H.M. Wisniewski and L.I. Binder, Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology, Proc Natl Acad Sci U S A 83 (1986), 4913-4917.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.C.3
Quinlan, M.4
Wisniewski, H.M.5
Binder, L.I.6
-
50
-
-
20044381844
-
Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease
-
A.L. Guillozet-Bongaarts, F. Garcia-Sierra, M.R. Reynolds, P.M. Horowitz, Y. Fu, T. Wang, M.E. Cahill, E.H. Bigio, R.W. Berry and L.I. Binder, Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease, Neurobiol Aging 26 (2005), 1015-1022.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 1015-1022
-
-
Guillozet-Bongaarts, A.L.1
Garcia-Sierra, F.2
Reynolds, M.R.3
Horowitz, P.M.4
Fu, Y.5
Wang, T.6
Cahill, M.E.7
Bigio, E.H.8
Berry, R.W.9
Binder, L.I.10
-
51
-
-
3242811902
-
Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease
-
H. Guo, S. Albrecht, M. Bourdeau, T. Petzke, C. Bergeron and A.C. LeBlanc, Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease, Am J Pathol 165 (2004), 523-531.
-
(2004)
Am J Pathol
, vol.165
, pp. 523-531
-
-
Guo, H.1
Albrecht, S.2
Bourdeau, M.3
Petzke, T.4
Bergeron, C.5
LeBlanc, A.C.6
-
52
-
-
0026053023
-
Measurement of distinct immunochemical presentations of tau protein in Alzheimer disease
-
C.R. Harrington, E.B. Mukaetova-Ladinska, R. Hills, P.C. Edwards, E. Montejo de Garcini, M. Novak and C.M. Wischik, Measurement of distinct immunochemical presentations of tau protein in Alzheimer disease, Proc Natl Acad Sci U S A 88 (1991), 5842-5846.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 5842-5846
-
-
Harrington, C.R.1
Mukaetova-Ladinska, E.B.2
Hills, R.3
Edwards, P.C.4
Montejo de Garcini, E.5
Novak, M.6
Wischik, C.M.7
-
53
-
-
33845974450
-
Removal of pattern-breaking sequences in microtubule binding repeats produces instantaneous tau aggregation and toxicity
-
A.I. Iliev, S. Ganesan, G. Bunt and F.S. Wouters, Removal of pattern-breaking sequences in microtubule binding repeats produces instantaneous tau aggregation and toxicity, J Biol Chem 281 (2006), 37195-37204.
-
(2006)
J Biol Chem
, vol.281
, pp. 37195-37204
-
-
Iliev, A.I.1
Ganesan, S.2
Bunt, G.3
Wouters, F.S.4
-
54
-
-
0032951956
-
Hierarchical phosphorylation of recombinant tau by the paired-helical filament-associated protein kinase is dependent on cyclic AMP-dependent protein kinase
-
G.A. Jicha, A. O'Donnell, C. Weaver, R. Angeletti and P. Davies, Hierarchical phosphorylation of recombinant tau by the paired-helical filament-associated protein kinase is dependent on cyclic AMP-dependent protein kinase, J Neurochem 72 (1999), 214-224.
-
(1999)
J Neurochem
, vol.72
, pp. 214-224
-
-
Jicha, G.A.1
O'Donnell, A.2
Weaver, C.3
Angeletti, R.4
Davies, P.5
-
55
-
-
0023905906
-
Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques
-
R. Katzman, R. Terry, R. DeTeresa, T. Brown, P. Davies, P. Fuld, X. Renbing and A. Peck, Clinical, pathological, and neurochemical changes in dementia: a subgroup with preserved mental status and numerous neocortical plaques, Ann Neurol 23 (1988), 138-144.
-
(1988)
Ann Neurol
, vol.23
, pp. 138-144
-
-
Katzman, R.1
Terry, R.2
DeTeresa, R.3
Brown, T.4
Davies, P.5
Fuld, P.6
Renbing, X.7
Peck, A.8
-
56
-
-
0037381710
-
Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease
-
S. Keck, R. Nitsch, T. Grune and O. Ullrich, Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease, J Neurochem 85 (2003), 115-122.
-
(2003)
J Neurochem
, vol.85
, pp. 115-122
-
-
Keck, S.1
Nitsch, R.2
Grune, T.3
Ullrich, O.4
-
57
-
-
33644851265
-
Inducible expression of Tau repeat domain in cell models of tauopathy: Aggregation is toxic to cells but can be reversed by inhibitor drugs
-
I. Khlistunova, J. Biernat, Y. Wang, M. Pickhardt, M. von Bergen, Z. Gazova, E. Mandelkow and E.M. Mandelkow, Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs, J Biol Chem 281 (2006), 1205-1214.
-
(2006)
J Biol Chem
, vol.281
, pp. 1205-1214
-
-
Khlistunova, I.1
Biernat, J.2
Wang, Y.3
Pickhardt, M.4
von Bergen, M.5
Gazova, Z.6
Mandelkow, E.7
Mandelkow, E.M.8
-
58
-
-
0022557177
-
Age-related modifications of MAP-2
-
K.S. Kosik, S. Bakalis, L. Galibert, D.J. Selkoe and L.K. Duffy, Age-related modifications of MAP-2, Ann N Y Acad Sci 466 (1986), 420-422.
-
(1986)
Ann N Y Acad Sci
, vol.466
, pp. 420-422
-
-
Kosik, K.S.1
Bakalis, S.2
Galibert, L.3
Selkoe, D.J.4
Duffy, L.K.5
-
59
-
-
10944273984
-
Pathways of tau fibrillization
-
J. Kuret, C.N. Chirita, E.E. Congdon, T. Kannanayakal, G. Li, M. Necula, H. Yin and Q. Zhong, Pathways of tau fibrillization, Biochim Biophys Acta 1739 (2005), 167-178.
-
(2005)
Biochim Biophys Acta
, vol.1739
, pp. 167-178
-
-
Kuret, J.1
Chirita, C.N.2
Congdon, E.E.3
Kannanayakal, T.4
Li, G.5
Necula, M.6
Yin, H.7
Zhong, Q.8
-
60
-
-
24144459823
-
Evaluating triggers and enhancers of tau fibrillization
-
J. Kuret, E.E. Congdon, G. Li, H. Yin, X. Yu and Q. Zhong, Evaluating triggers and enhancers of tau fibrillization, Microsc Res Tech 67 (2005), 141-155.
-
(2005)
Microsc Res Tech
, vol.67
, pp. 141-155
-
-
Kuret, J.1
Congdon, E.E.2
Li, G.3
Yin, H.4
Yu, X.5
Zhong, Q.6
-
61
-
-
33745449875
-
An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice
-
S. Le Corre, H.W. Klafki, N. Plesnila, G. Hubinger, A. Obermeier, H. Sahagun, B. Monse, P. Seneci, J. Lewis, J. Eriksen, C. Zehr, M. Yue, E. McGowan, D.W. Dickson, M. Hutton and H.M. Roder, An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice, Proc Natl Acad Sci U S A 103 (2006), 9673-9678.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 9673-9678
-
-
Le Corre, S.1
Klafki, H.W.2
Plesnila, N.3
Hubinger, G.4
Obermeier, A.5
Sahagun, H.6
Monse, B.7
Seneci, P.8
Lewis, J.9
Eriksen, J.10
Zehr, C.11
Yue, M.12
McGowan, E.13
Dickson, D.W.14
Hutton, M.15
Roder, H.M.16
-
62
-
-
0025904444
-
A68: A major subunit of paired helical filaments and derivatized forms of normal Tau
-
V.M. Lee, B.J. Balin, L. Otvos, Jr. and J.Q. Trojanowski, A68: a major subunit of paired helical filaments and derivatized forms of normal Tau, Science 251 (1991), 675-678.
-
(1991)
Science
, vol.251
, pp. 675-678
-
-
Lee, V.M.1
Balin, B.J.2
Otvos Jr., L.3
Trojanowski, J.Q.4
-
64
-
-
33847674888
-
Phosphorylation of tau antagonizes apoptosis by stabilizing beta-catenin, a mechanism involved in Alzheimer's neurodegeneration
-
H.L. Li, H.H. Wang, S.J. Liu, Y.Q. Deng, Y.J. Zhang, Q. Tian, X.C. Wang, X.Q. Chen, Y. Yang, J.Y. Zhang, Q. Wang, H. Xu, F.F. Liao and J.Z. Wang, Phosphorylation of tau antagonizes apoptosis by stabilizing beta-catenin, a mechanism involved in Alzheimer's neurodegeneration, Proc Natl Acad Sci U S A 104 (2007), 3591-3596.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3591-3596
-
-
Li, H.L.1
Wang, H.H.2
Liu, S.J.3
Deng, Y.Q.4
Zhang, Y.J.5
Tian, Q.6
Wang, X.C.7
Chen, X.Q.8
Yang, Y.9
Zhang, J.Y.10
Wang, Q.11
Xu, H.12
Liao, F.F.13
Wang, J.Z.14
-
65
-
-
24644433910
-
Regional conformational change involving phosphorylation of tau protein at the Thr231, precedes the structural change detected by Alz-50 antibody in Alzheimer's disease
-
J. Luna-Munoz, F. Garcia-Sierra, V. Falcon, I. Menendez, L. Chavez-Macias and R. Mena, Regional conformational change involving phosphorylation of tau protein at the Thr231, precedes the structural change detected by Alz-50 antibody in Alzheimer's disease, J Alzheimers Dis 8 (2005), 29-41.
-
(2005)
J Alzheimers Dis
, vol.8
, pp. 29-41
-
-
Luna-Munoz, J.1
Garcia-Sierra, F.2
Falcon, V.3
Menendez, I.4
Chavez-Macias, L.5
Mena, R.6
-
66
-
-
38049030324
-
Earliest stages of tau conformational changes are related to the appearance of a sequence of specific phospho-dependent tau epitopes in Alzheimer's disease
-
J. Luna-Munoz, L. Chavez-Macias, F. Garcia-Sierra and R. Mena, Earliest stages of tau conformational changes are related to the appearance of a sequence of specific phospho-dependent tau epitopes in Alzheimer's disease, J Alzheimers Dis 12 (2007), 365-375.
-
(2007)
J Alzheimers Dis
, vol.12
, pp. 365-375
-
-
Luna-Munoz, J.1
Chavez-Macias, L.2
Garcia-Sierra, F.3
Mena, R.4
-
67
-
-
0029018840
-
The role of tau phosphorylation in transfected COS-1 cells
-
M. Medina, E. Montejo de Garcini and J. Avila, The role of tau phosphorylation in transfected COS-1 cells, Mol Cell Biochem 148 (1995), 79-88.
-
(1995)
Mol Cell Biochem
, vol.148
, pp. 79-88
-
-
Medina, M.1
Montejo de Garcini, E.2
Avila, J.3
-
68
-
-
0029997922
-
Staging the pathological assembly of truncated tau protein into paired helical filaments in Alzheimer's disease
-
R. Mena, P.C. Edwards, C.R. Harrington, E.B. Mukaetova-Ladinska and C.M. Wischik, Staging the pathological assembly of truncated tau protein into paired helical filaments in Alzheimer's disease, Acta Neuropathol (Berl) 91 (1996), 633-641.
-
(1996)
Acta Neuropathol (Berl)
, vol.91
, pp. 633-641
-
-
Mena, R.1
Edwards, P.C.2
Harrington, C.R.3
Mukaetova-Ladinska, E.B.4
Wischik, C.M.5
-
69
-
-
0036889671
-
Membrane destabilization induced by beta-amyloid peptide 29-42: Importance of the amino-terminus
-
M.P. Mingeot-Leclercq, L. Lins, M. Bensliman, F. Van Bambeke, P. Van Der Smissen, J. Peuvot, A. Schanck and R. Brasseur, Membrane destabilization induced by beta-amyloid peptide 29-42: importance of the amino-terminus, Chem Phys Lipids 120 (2002), 57-74.
-
(2002)
Chem Phys Lipids
, vol.120
, pp. 57-74
-
-
Mingeot-Leclercq, M.P.1
Lins, L.2
Bensliman, M.3
Van Bambeke, F.4
Van Der Smissen, P.5
Peuvot, J.6
Schanck, A.7
Brasseur, R.8
-
70
-
-
23844459221
-
Visualization of newly deposited tau in neurofibrillary tangles and neuropil threads
-
T. Miyasaka, A. Watanabe, Y. Saito, S. Murayama, D.M. Mann, M. Yamazaki, R. Ravid, M. Morishima-Kawashima, K. Nagashima and Y. Ihara, Visualization of newly deposited tau in neurofibrillary tangles and neuropil threads, J Neuropathol Exp Neurol 64 (2005), 665-674.
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, pp. 665-674
-
-
Miyasaka, T.1
Watanabe, A.2
Saito, Y.3
Murayama, S.4
Mann, D.M.5
Yamazaki, M.6
Ravid, R.7
Morishima-Kawashima, M.8
Nagashima, K.9
Ihara, Y.10
-
71
-
-
38549129613
-
The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy
-
M.M. Mocanu, A. Nissen, K. Eckermann, I. Khlistunova, J. Biernat, D. Drexler, O. Petrova, K. Schonig, H. Bujard, E. Mandelkow, L. Zhou, G. Rune and E.M. Mandelkow, The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy, J Neurosci 28 (2008), 737-748.
-
(2008)
J Neurosci
, vol.28
, pp. 737-748
-
-
Mocanu, M.M.1
Nissen, A.2
Eckermann, K.3
Khlistunova, I.4
Biernat, J.5
Drexler, D.6
Petrova, O.7
Schonig, K.8
Bujard, H.9
Mandelkow, E.10
Zhou, L.11
Rune, G.12
Mandelkow, E.M.13
-
72
-
-
40549124991
-
Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease
-
in press
-
S. Mondragon-Rodriguez, G. Basurto-Islas, I. Santa-Maria, R. Mena, L.I. Binder, J. Avila, M.A. Smith, G. Perry and F. Garcia-Sierra, Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease, Int J Exp Path (2008), in press.
-
(2008)
Int J Exp Path
-
-
Mondragon-Rodriguez, S.1
Basurto-Islas, G.2
Santa-Maria, I.3
Mena, R.4
Binder, L.I.5
Avila, J.6
Smith, M.A.7
Perry, G.8
Garcia-Sierra, F.9
-
73
-
-
38149085203
-
-
S. Mondragon-Rodriguez, R. Mena, L.I. Binder, M.A. Smith, G. Perry and F. Garcia-Sierra, Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology, Neuropathol Appl Neurobiol 34 (2008), 62-75.
-
S. Mondragon-Rodriguez, R. Mena, L.I. Binder, M.A. Smith, G. Perry and F. Garcia-Sierra, Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology, Neuropathol Appl Neurobiol 34 (2008), 62-75.
-
-
-
-
74
-
-
0028267537
-
Overexpression of tau protein in COS-1 cells results in the stabilization of centrosome-independent microtubules and extension of cytoplasmic processes
-
E. Montejo de Garcini, S. de la Luna, J.E. Dominguez and J. Avila, Overexpression of tau protein in COS-1 cells results in the stabilization of centrosome-independent microtubules and extension of cytoplasmic processes, Mol Cell Biochem 130 (1994), 187-196.
-
(1994)
Mol Cell Biochem
, vol.130
, pp. 187-196
-
-
Montejo de Garcini, E.1
de la Luna, S.2
Dominguez, J.E.3
Avila, J.4
-
75
-
-
0029687051
-
Classification of dementia and Alzheimer's disease
-
J.C. Morris, Classification of dementia and Alzheimer's disease, Acta Neurol Scand Suppl 165 (1996), 41-50.
-
(1996)
Acta Neurol Scand Suppl
, vol.165
, pp. 41-50
-
-
Morris, J.C.1
-
76
-
-
0027731224
-
Biochemical and anatomical redistribution of tau protein in Alzheimer's disease
-
E.B. Mukaetova-Ladinska, C.R. Harrington, M. Roth and C.M. Wischik, Biochemical and anatomical redistribution of tau protein in Alzheimer's disease, Am J Pathol 143 (1993), 565-578.
-
(1993)
Am J Pathol
, vol.143
, pp. 565-578
-
-
Mukaetova-Ladinska, E.B.1
Harrington, C.R.2
Roth, M.3
Wischik, C.M.4
-
77
-
-
0033899864
-
Staging of cytoskeletal and beta-amyloid changes in human isocortex reveals biphasic synaptic protein response during progression of Alzheimer's disease
-
E.B. Mukaetova-Ladinska, F. Garcia-Siera, J. Hurt, H.J. Gertz, J.H. Xuereb, R. Hills, C. Brayne, F.A. Huppert, E.S. Paykel, M. McGee, R. Jakes, W.G. Honer, C.R. Harrington and C.M. Wischik, Staging of cytoskeletal and beta-amyloid changes in human isocortex reveals biphasic synaptic protein response during progression of Alzheimer's disease, Am J Pathol 157 (2000), 623-636.
-
(2000)
Am J Pathol
, vol.157
, pp. 623-636
-
-
Mukaetova-Ladinska, E.B.1
Garcia-Siera, F.2
Hurt, J.3
Gertz, H.J.4
Xuereb, J.H.5
Hills, R.6
Brayne, C.7
Huppert, F.A.8
Paykel, E.S.9
McGee, M.10
Jakes, R.11
Honer, W.G.12
Harrington, C.R.13
Wischik, C.M.14
-
78
-
-
35748974225
-
Protection against beta-amyloid-induced apoptosis by peptides interacting with beta-amyloid
-
T.J. Nelson and D.L. Alkon, Protection against beta-amyloid-induced apoptosis by peptides interacting with beta-amyloid, J Biol Chem 282 (2007), 31238-31249.
-
(2007)
J Biol Chem
, vol.282
, pp. 31238-31249
-
-
Nelson, T.J.1
Alkon, D.L.2
-
79
-
-
24344508845
-
Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology
-
J. Newman, R.A. Rissman, F. Sarsoza, R.C. Kim, M. Dick, D.A. Bennett, C.W. Cotman, T.T. Rohn and E. Head, Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology, Acta Neuropathol 110 (2005), 135-144.
-
(2005)
Acta Neuropathol
, vol.110
, pp. 135-144
-
-
Newman, J.1
Rissman, R.A.2
Sarsoza, F.3
Kim, R.C.4
Dick, M.5
Bennett, D.A.6
Cotman, C.W.7
Rohn, T.T.8
Head, E.9
-
80
-
-
0142156075
-
Age-dependent changes in axonal transport and cellular distribution of Tau 1 in the rat basal forebrain neurons
-
G. Niewiadomska and M. Baksalerska-Pazera, Age-dependent changes in axonal transport and cellular distribution of Tau 1 in the rat basal forebrain neurons, Neuroreport 14 (2003), 1701-1706.
-
(2003)
Neuroreport
, vol.14
, pp. 1701-1706
-
-
Niewiadomska, G.1
Baksalerska-Pazera, M.2
-
81
-
-
25144517127
-
Altered cellular distribution of phospho-tau proteins coincides with impaired retrograde axonal transport in neurons of aged rats
-
G. Niewiadomska, M. Baksalerska-Pazera and G. Riedel, Altered cellular distribution of phospho-tau proteins coincides with impaired retrograde axonal transport in neurons of aged rats, Ann N Y Acad Sci 1048 (2005), 287-295.
-
(2005)
Ann N Y Acad Sci
, vol.1048
, pp. 287-295
-
-
Niewiadomska, G.1
Baksalerska-Pazera, M.2
Riedel, G.3
-
82
-
-
0026053022
-
Difference between the tau protein of Alzheimer paired helical filament core and normal tau revealed by epitope analysis of monoclonal antibodies 423 and 7.51
-
M. Novak, R. Jakes, P.C. Edwards, C. Milstein and C.M. Wischik, Difference between the tau protein of Alzheimer paired helical filament core and normal tau revealed by epitope analysis of monoclonal antibodies 423 and 7.51, Proc Natl Acad Sci U S A 88 (1991), 5837-5841.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 5837-5841
-
-
Novak, M.1
Jakes, R.2
Edwards, P.C.3
Milstein, C.4
Wischik, C.M.5
-
83
-
-
0027398169
-
Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filament
-
M. Novak, J. Kabat and C.M. Wischik, Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filament, Embo J 12 (1993), 365-370.
-
(1993)
Embo J
, vol.12
, pp. 365-370
-
-
Novak, M.1
Kabat, J.2
Wischik, C.M.3
-
84
-
-
33751557958
-
Caspase-3- and calpain-mediated tau cleavage are differentially prevented by estrogen and testosterone in beta-amyloid-treated hippocampal neurons
-
S.Y. Park, C. Tournell, R.C. Sinjoanu and A. Ferreira, Caspase-3- and calpain-mediated tau cleavage are differentially prevented by estrogen and testosterone in beta-amyloid-treated hippocampal neurons, Neuroscience 144 (2007), 119-127.
-
(2007)
Neuroscience
, vol.144
, pp. 119-127
-
-
Park, S.Y.1
Tournell, C.2
Sinjoanu, R.C.3
Ferreira, A.4
-
85
-
-
0035027964
-
Abortive apoptosis in Alzheimer's disease
-
A.K. Raina, A. Hochman, X. Zhu, C.A. Rottkamp, A. Nunomura, S.L. Siedlak, H. Boux, R.J. Castellani, G. Perry and M.A. Smith, Abortive apoptosis in Alzheimer's disease, Acta Neuropathol (Berl) 101 (2001), 305-310.
-
(2001)
Acta Neuropathol (Berl)
, vol.101
, pp. 305-310
-
-
Raina, A.K.1
Hochman, A.2
Zhu, X.3
Rottkamp, C.A.4
Nunomura, A.5
Siedlak, S.L.6
Boux, H.7
Castellani, R.J.8
Perry, G.9
Smith, M.A.10
-
86
-
-
27744435409
-
Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice
-
E.M. Ribe, M. Perez, B. Puig, I. Gich, F. Lim, M. Cuadrado, T. Sesma, S. Catena, B. Sanchez, M. Nieto, P. Gomez-Ramos, M.A. Moran, F. Cabodevilla, L. Samaranch, L. Ortiz, A. Perez, I. Ferrer, J. Avila and T. Gomez-Isla, Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice, Neurobiol Dis 20 (2005), 814-822.
-
(2005)
Neurobiol Dis
, vol.20
, pp. 814-822
-
-
Ribe, E.M.1
Perez, M.2
Puig, B.3
Gich, I.4
Lim, F.5
Cuadrado, M.6
Sesma, T.7
Catena, S.8
Sanchez, B.9
Nieto, M.10
Gomez-Ramos, P.11
Moran, M.A.12
Cabodevilla, F.13
Samaranch, L.14
Ortiz, L.15
Perez, A.16
Ferrer, I.17
Avila, J.18
Gomez-Isla, T.19
-
87
-
-
3242749074
-
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology
-
R.A. Rissman, W.W. Poon, M. Blurton-Jones, S. Oddo, R. Torp, M.P. Vitek, F.M. LaFerla, T.T. Rohn and C.W. Cotman, Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology, J Clin Invest 114 (2004), 121-130.
-
(2004)
J Clin Invest
, vol.114
, pp. 121-130
-
-
Rissman, R.A.1
Poon, W.W.2
Blurton-Jones, M.3
Oddo, S.4
Torp, R.5
Vitek, M.P.6
LaFerla, F.M.7
Rohn, T.T.8
Cotman, C.W.9
-
88
-
-
0035664134
-
Activation of caspase-8 in the Alzheimer's disease brain
-
T.T. Rohn, E. Head, W.H. Nesse, C.W. Cotman and D.H. Cribbs, Activation of caspase-8 in the Alzheimer's disease brain, Neurobiol Dis 8 (2001), 1006-1016.
-
(2001)
Neurobiol Dis
, vol.8
, pp. 1006-1016
-
-
Rohn, T.T.1
Head, E.2
Nesse, W.H.3
Cotman, C.W.4
Cribbs, D.H.5
-
89
-
-
0035141757
-
Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease
-
T.T. Rohn, E. Head, J.H. Su, A.J. Anderson, B.A. Bahr, C.W. Cotman and D.H. Cribbs, Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease, Am J Pathol 158 (2001), 189-198.
-
(2001)
Am J Pathol
, vol.158
, pp. 189-198
-
-
Rohn, T.T.1
Head, E.2
Su, J.H.3
Anderson, A.J.4
Bahr, B.A.5
Cotman, C.W.6
Cribbs, D.H.7
-
90
-
-
33750363298
-
The roles of intracellular protein-degradation pathways in neurodegeneration
-
D.C. Rubinsztein, The roles of intracellular protein-degradation pathways in neurodegeneration, Nature 443 (2006), 780-786.
-
(2006)
Nature
, vol.443
, pp. 780-786
-
-
Rubinsztein, D.C.1
-
91
-
-
0025973319
-
Severity of dementia in Alzheimer disease and neurofibrillary tangles in multiple brain regions
-
W.A. Samuel, V.W. Henderson and C.A. Miller, Severity of dementia in Alzheimer disease and neurofibrillary tangles in multiple brain regions, Alzheimer Dis Assoc Disord 5 (1991), 1-11.
-
(1991)
Alzheimer Dis Assoc Disord
, vol.5
, pp. 1-11
-
-
Samuel, W.A.1
Henderson, V.W.2
Miller, C.A.3
-
92
-
-
33746797661
-
In vitro tau fibrillization: Mapping protein regions
-
I. Santa-Maria, M. Perez, F. Hernandez, V. Munoz, F.J. Moreno and J. Avila, In vitro tau fibrillization: mapping protein regions, Biochim Biophys Acta 1762 (2006), 683-692.
-
(2006)
Biochim Biophys Acta
, vol.1762
, pp. 683-692
-
-
Santa-Maria, I.1
Perez, M.2
Hernandez, F.3
Munoz, V.4
Moreno, F.J.5
Avila, J.6
-
93
-
-
35748977086
-
Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau
-
I. Santa-Maria, F. Hernandez, J. Del Rio, F.J. Moreno and J. Avila, Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau, Mol Neurodegener 2 (2007), 17.
-
(2007)
Mol Neurodegener
, vol.2
, pp. 17
-
-
Santa-Maria, I.1
Hernandez, F.2
Del Rio, J.3
Moreno, F.J.4
Avila, J.5
-
94
-
-
13644249113
-
Chronological primacy of oxidative stress in Alzheimer disease
-
M.A. Smith, A. Nunomura, H.G. Lee, X. Zhu, P.I. Moreira, J. Avila and G. Perry, Chronological primacy of oxidative stress in Alzheimer disease, Neurobiol Aging 26 (2005), 579-580.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 579-580
-
-
Smith, M.A.1
Nunomura, A.2
Lee, H.G.3
Zhu, X.4
Moreira, P.I.5
Avila, J.6
Perry, G.7
-
95
-
-
0344944630
-
Protein aggregation and aggregate toxicity: New insights into protein folding, misfolding diseases and biological evolution
-
M. Stefani and C.M. Dobson, Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution, J Mol Med 81 (2003), 678-699.
-
(2003)
J Mol Med
, vol.81
, pp. 678-699
-
-
Stefani, M.1
Dobson, C.M.2
-
96
-
-
33746355958
-
Axonal transport and Alzheimer's disease
-
G.B. Stokin and L.S. Goldstein, Axonal transport and Alzheimer's disease, Annu Rev Biochem 75 (2006), 607-627.
-
(2006)
Annu Rev Biochem
, vol.75
, pp. 607-627
-
-
Stokin, G.B.1
Goldstein, L.S.2
-
97
-
-
0036934466
-
Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain
-
J.H. Su, J.P. Kesslak, E. Head and C.W. Cotman, Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain, Acta Neuropathol 104 (2002), 1-6.
-
(2002)
Acta Neuropathol
, vol.104
, pp. 1-6
-
-
Su, J.H.1
Kesslak, J.P.2
Head, E.3
Cotman, C.W.4
-
98
-
-
1542357632
-
Amyloid beta peptide-induced cerebral neuronal loss is mediated by caspase-3 in vivo
-
H. Takuma, T. Tomiyama, K. Kuida and H. Mori, Amyloid beta peptide-induced cerebral neuronal loss is mediated by caspase-3 in vivo, J Neuropathol Exp Neurol 63 (2004), 255-261.
-
(2004)
J Neuropathol Exp Neurol
, vol.63
, pp. 255-261
-
-
Takuma, H.1
Tomiyama, T.2
Kuida, K.3
Mori, H.4
-
99
-
-
34248190279
-
A beta oligomers - a decade of discovery
-
D.M. Walsh and D.J. Selkoe, A beta oligomers - a decade of discovery, J Neurochem 101 (2007), 1172-1184.
-
(2007)
J Neurochem
, vol.101
, pp. 1172-1184
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
100
-
-
18144406844
-
Proteomic analysis of neurofibrillary tangles in Alzheimer disease identifies GAPDH as a detergent-insoluble paired helical filament tau binding protein
-
Q. Wang, R.L. Woltjer, P.J. Cimino, C. Pan, K.S. Montine, J. Zhang and T.J. Montine, Proteomic analysis of neurofibrillary tangles in Alzheimer disease identifies GAPDH as a detergent-insoluble paired helical filament tau binding protein, Faseb J 19 (2005), 869-871.
-
(2005)
Faseb J
, vol.19
, pp. 869-871
-
-
Wang, Q.1
Woltjer, R.L.2
Cimino, P.J.3
Pan, C.4
Montine, K.S.5
Zhang, J.6
Montine, T.J.7
-
101
-
-
34547203592
-
Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model
-
Y.P. Wang, J. Biernat, M. Pickhardt, E. Mandelkow and E.M. Mandelkow, Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model, Proc Natl Acad Sci U S A 104 (2007), 10252-10257.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 10252-10257
-
-
Wang, Y.P.1
Biernat, J.2
Pickhardt, M.3
Mandelkow, E.4
Mandelkow, E.M.5
-
102
-
-
33751034682
-
Aggregate-prone proteins are cleared from the cytosol by autophagy: Therapeutic implications
-
A. Williams, L. Jahreiss, S. Sarkar, S. Saiki, F.M. Menzies, B. Ravikumar and D.C. Rubinsztein, Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications, Curr Top Dev Biol 76 (2006), 89-101.
-
(2006)
Curr Top Dev Biol
, vol.76
, pp. 89-101
-
-
Williams, A.1
Jahreiss, L.2
Sarkar, S.3
Saiki, S.4
Menzies, F.M.5
Ravikumar, B.6
Rubinsztein, D.C.7
-
103
-
-
0024044195
-
Structural characterization of the core of the paired helical filament of Alzheimer disease
-
C.M. Wischik, M. Novak, P.C. Edwards, A. Klug, W. Tichelaar and R.A. Crowther, Structural characterization of the core of the paired helical filament of Alzheimer disease, Proc Natl Acad Sci U S A 85 (1988), 4884-4888.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 4884-4888
-
-
Wischik, C.M.1
Novak, M.2
Edwards, P.C.3
Klug, A.4
Tichelaar, W.5
Crowther, R.A.6
-
104
-
-
0003986552
-
Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease
-
C.M. Wischik, M. Novak, H.C. Thogersen, P.C. Edwards, M.J. Runswick, R. Jakes, J.E. Walker, C. Milstein, M. Roth and A. Klug, Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease, Proc Natl Acad Sci U S A 85 (1988), 4506-4510.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 4506-4510
-
-
Wischik, C.M.1
Novak, M.2
Thogersen, H.C.3
Edwards, P.C.4
Runswick, M.J.5
Jakes, R.6
Walker, J.E.7
Milstein, C.8
Roth, M.9
Klug, A.10
-
105
-
-
0028998417
-
Quantitative analysis of tau protein in paired helical filament preparations: Implications for the role of tau protein phosphorylation in PHF assembly in Alzheimer's disease
-
discussion 418-431
-
C.M. Wischik, P.C. Edwards, R.Y. Lai, H.N. Gertz, J.H. Xuereb, E.S. Paykel, C. Brayne, F.A. Huppert, E.B. Mukaetova-Ladinska, R. Mena and et al., Quantitative analysis of tau protein in paired helical filament preparations: implications for the role of tau protein phosphorylation in PHF assembly in Alzheimer's disease, Neurobiol Aging 16 (1995), 409-417; discussion 418-431.
-
(1995)
Neurobiol Aging
, vol.16
, pp. 409-417
-
-
Wischik, C.M.1
Edwards, P.C.2
Lai, R.Y.3
Gertz, H.N.4
Xuereb, J.H.5
Paykel, E.S.6
Brayne, C.7
Huppert, F.A.8
Mukaetova-Ladinska, E.B.9
Mena, R.10
and et, al.11
-
106
-
-
0035958642
-
Tauopathy in Drosophila: Neurodegeneration without neurofibrillary tangles
-
C.W. Wittmann, M.F. Wszolek, J.M. Shulman, P.M. Salvaterra, J. Lewis, M. Hutton and M.B. Feany, Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles, Science 293 (2001), 711-714.
-
(2001)
Science
, vol.293
, pp. 711-714
-
-
Wittmann, C.W.1
Wszolek, M.F.2
Shulman, J.M.3
Salvaterra, P.M.4
Lewis, J.5
Hutton, M.6
Feany, M.B.7
-
107
-
-
24644511602
-
Oxidative imbalance in Alzheimer's disease
-
X. Zhu, H.G. Lee, G. Casadesus, J. Avila, K. Drew, G. Perry and M.A. Smith, Oxidative imbalance in Alzheimer's disease, Mol Neurobiol 31 (2005), 205-217.
-
(2005)
Mol Neurobiol
, vol.31
, pp. 205-217
-
-
Zhu, X.1
Lee, H.G.2
Casadesus, G.3
Avila, J.4
Drew, K.5
Perry, G.6
Smith, M.A.7
|