-
2
-
-
37049048544
-
Paired helical filaments in electron microscopy of Alzheimer's disease
-
Kidd M. Paired helical filaments in electron microscopy of Alzheimer's disease. Nature 197 (1963) 192-193
-
(1963)
Nature
, vol.197
, pp. 192-193
-
-
Kidd, M.1
-
3
-
-
0023009658
-
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments
-
Grundke-Iqbal I., Iqbal K., Quinlan M., Tung Y.C., Zaidi M.S., and Wisniewski H.M. Microtubule-associated protein tau. A component of Alzheimer paired helical filaments. J. Biol. Chem. 261 (1986) 6084-6089
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 6084-6089
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Quinlan, M.3
Tung, Y.C.4
Zaidi, M.S.5
Wisniewski, H.M.6
-
5
-
-
1842685948
-
Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau)
-
Wood J.G., Mirra S.S., Pollock N.J., and Binder L.I. Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau). Proc. Natl. Acad. Sci. U. S. A. 83 (1986) 4040-4043
-
(1986)
Proc. Natl. Acad. Sci. U. S. A.
, vol.83
, pp. 4040-4043
-
-
Wood, J.G.1
Mirra, S.S.2
Pollock, N.J.3
Binder, L.I.4
-
6
-
-
0009364134
-
Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease
-
Kosik K.S., Joachim C.L., and Selkoe D.J. Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease. Proc. Natl. Acad. Sci. U. S. A. 83 (1986) 4044-4048
-
(1986)
Proc. Natl. Acad. Sci. U. S. A.
, vol.83
, pp. 4044-4048
-
-
Kosik, K.S.1
Joachim, C.L.2
Selkoe, D.J.3
-
7
-
-
0022724941
-
Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease
-
Ihara Y., Nukina N., Miura R., and Ogawara M. Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease. J. Biochem. (Tokyo) 99 (1986) 1807-1810
-
(1986)
J. Biochem. (Tokyo)
, vol.99
, pp. 1807-1810
-
-
Ihara, Y.1
Nukina, N.2
Miura, R.3
Ogawara, M.4
-
8
-
-
0024044195
-
Structural characterization of the core of the paired helical filament of Alzheimer disease
-
Wischik C.M., Novak M., Edwards P.C., Klug A., Tichelaar W., and Crowther R.A. Structural characterization of the core of the paired helical filament of Alzheimer disease. Proc. Natl. Acad. Sci. U. S. A. 85 (1988) 4884-4888
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 4884-4888
-
-
Wischik, C.M.1
Novak, M.2
Edwards, P.C.3
Klug, A.4
Tichelaar, W.5
Crowther, R.A.6
-
9
-
-
0002792366
-
Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau
-
Goedert M., Wischik C.M., Crowther R.A., Walker J.E., and Klug A. Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau. Proc. Natl. Acad. Sci. U. S. A. 85 (1988) 4051-4055
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 4051-4055
-
-
Goedert, M.1
Wischik, C.M.2
Crowther, R.A.3
Walker, J.E.4
Klug, A.5
-
10
-
-
0022917474
-
Self assembly of microtubule associated protein tau into filaments resembling those found in Alzheimer disease
-
Montejo de Garcini E., Serrano L., and Avila J. Self assembly of microtubule associated protein tau into filaments resembling those found in Alzheimer disease. Biochem. Biophys. Res. Commun. 141 (1986) 790-796
-
(1986)
Biochem. Biophys. Res. Commun.
, vol.141
, pp. 790-796
-
-
Montejo de Garcini, E.1
Serrano, L.2
Avila, J.3
-
12
-
-
0025904444
-
A68: a major subunit of paired helical filaments and derivatized forms of normal Tau
-
Lee V.M., Balin B.J., Otvos Jr. L., and Trojanowski J.Q. A68: a major subunit of paired helical filaments and derivatized forms of normal Tau. Science 251 (1991) 675-678
-
(1991)
Science
, vol.251
, pp. 675-678
-
-
Lee, V.M.1
Balin, B.J.2
Otvos Jr., L.3
Trojanowski, J.Q.4
-
13
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
-
Grundke-Iqbal I., Iqbal K., Tung Y.C., Quinlan M., Wisniewski H.M., and Binder L.I. Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc. Natl. Acad. Sci. U. S. A. 83 (1986) 4913-4917
-
(1986)
Proc. Natl. Acad. Sci. U. S. A.
, vol.83
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.C.3
Quinlan, M.4
Wisniewski, H.M.5
Binder, L.I.6
-
14
-
-
0033850407
-
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders
-
Buee L., Bussiere T., Buee-Scherrer V., Delacourte A., and Hof P.R. Tau protein isoforms, phosphorylation and role in neurodegenerative disorders. Brain Res. Brain Res. Rev. 33 (2000) 95-130
-
(2000)
Brain Res. Brain Res. Rev.
, vol.33
, pp. 95-130
-
-
Buee, L.1
Bussiere, T.2
Buee-Scherrer, V.3
Delacourte, A.4
Hof, P.R.5
-
16
-
-
9044229145
-
On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants
-
Lomakin A., Chung D.S., Benedek G.B., Kirschner D.A., and Teplow D.B. On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 1125-1129
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 1125-1129
-
-
Lomakin, A.1
Chung, D.S.2
Benedek, G.B.3
Kirschner, D.A.4
Teplow, D.B.5
-
17
-
-
0026799198
-
The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease
-
Crowther R.A., Olesen O.F., Jakes R., and Goedert M. The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease. FEBS Lett. 309 (1992) 199-202
-
(1992)
FEBS Lett.
, vol.309
, pp. 199-202
-
-
Crowther, R.A.1
Olesen, O.F.2
Jakes, R.3
Goedert, M.4
-
18
-
-
0035811050
-
Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments
-
Alonso A., Zaidi T., Novak M., Grundke-Iqbal I., and Iqbal K. Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 6923-6928
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 6923-6928
-
-
Alonso, A.1
Zaidi, T.2
Novak, M.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
19
-
-
0028065142
-
Analysis of microtubule-associated protein tau glycation in paired helical filaments
-
Ledesma M.D., Bonay P., Colaço C., and Avila J. Analysis of microtubule-associated protein tau glycation in paired helical filaments. J. Biol. Chem. 269 (1994) 21614-21619
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 21614-21619
-
-
Ledesma, M.D.1
Bonay, P.2
Colaço, C.3
Avila, J.4
-
20
-
-
0028023944
-
Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress
-
Yan S.D., Chen X., Schmidt A.M., Brett J., Godman G., Zou Y.S., Scott C.W., Caputo C., Frappier T., Smith M.A., et al. Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 7787-7791
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 7787-7791
-
-
Yan, S.D.1
Chen, X.2
Schmidt, A.M.3
Brett, J.4
Godman, G.5
Zou, Y.S.6
Scott, C.W.7
Caputo, C.8
Frappier, T.9
Smith, M.A.10
-
21
-
-
0033548661
-
Deamidation and isoaspartate formation in smeared tau in paired helical filaments. Unusual properties of the microtubule-binding domain of tau
-
Watanabe A., Takio K., and Ihara Y. Deamidation and isoaspartate formation in smeared tau in paired helical filaments. Unusual properties of the microtubule-binding domain of tau. J. Biol. Chem. 274 (1999) 7368-7378
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7368-7378
-
-
Watanabe, A.1
Takio, K.2
Ihara, Y.3
-
22
-
-
0027398169
-
Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filament
-
Novak M., Kabat J., and Wischik C.M. Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filament. EMBO J. 12 (1993) 365-370
-
(1993)
EMBO J.
, vol.12
, pp. 365-370
-
-
Novak, M.1
Kabat, J.2
Wischik, C.M.3
-
23
-
-
0029907548
-
Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans
-
Goedert M., Jakes R., Spillantini M.G., Hasegawa M., Smith M.J., and Crowther R.A. Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Nature 383 (1996) 550-553
-
(1996)
Nature
, vol.383
, pp. 550-553
-
-
Goedert, M.1
Jakes, R.2
Spillantini, M.G.3
Hasegawa, M.4
Smith, M.J.5
Crowther, R.A.6
-
24
-
-
0029796168
-
Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction
-
Perez M., Valpuesta J.M., Medina M., Montejo de Garcini E., and Avila J. Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction. J. Neurochem. 67 (1996) 1183-1190
-
(1996)
J. Neurochem.
, vol.67
, pp. 1183-1190
-
-
Perez, M.1
Valpuesta, J.M.2
Medina, M.3
Montejo de Garcini, E.4
Avila, J.5
-
25
-
-
0030590911
-
RNA stimulates aggregation of microtubule-associated protein tau into Alzheimer-like paired helical filaments
-
Kampers T., Friedhoff P., Biernat J., Mandelkow E.M., and Mandelkow E. RNA stimulates aggregation of microtubule-associated protein tau into Alzheimer-like paired helical filaments. FEBS Lett. 399 (1996) 344-349
-
(1996)
FEBS Lett.
, vol.399
, pp. 344-349
-
-
Kampers, T.1
Friedhoff, P.2
Biernat, J.3
Mandelkow, E.M.4
Mandelkow, E.5
-
26
-
-
0030923223
-
Free fatty acids stimulate the polymerization of tau and amyloid beta peptides. In vitro evidence for a common effector of pathogenesis in Alzheimer's disease
-
Wilson D.M., and Binder L.I. Free fatty acids stimulate the polymerization of tau and amyloid beta peptides. In vitro evidence for a common effector of pathogenesis in Alzheimer's disease. Am. J. Pathol. 150 (1997) 2181-2195
-
(1997)
Am. J. Pathol.
, vol.150
, pp. 2181-2195
-
-
Wilson, D.M.1
Binder, L.I.2
-
27
-
-
0034700253
-
Oxidative regulation of fatty acid-induced tau polymerization
-
Gamblin T.C., King M.E., Kuret J., Berry R.W., and Binder L.I. Oxidative regulation of fatty acid-induced tau polymerization. Biochemistry 39 (2000) 14203-14210
-
(2000)
Biochemistry
, vol.39
, pp. 14203-14210
-
-
Gamblin, T.C.1
King, M.E.2
Kuret, J.3
Berry, R.W.4
Binder, L.I.5
-
28
-
-
0034672554
-
Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4-hydroxy-2-nonenal
-
Perez M., Cuadros R., Smith M.A., Perry G., and Avila J. Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4-hydroxy-2-nonenal. FEBS Lett. 486 (2000) 270-274
-
(2000)
FEBS Lett.
, vol.486
, pp. 270-274
-
-
Perez, M.1
Cuadros, R.2
Smith, M.A.3
Perry, G.4
Avila, J.5
-
29
-
-
12144289142
-
Quinones facilitate the self-assembly of the phosphorylated tubulin binding region of tau into fibrillar polymers
-
Santa-Maria I., Hernandez F., Martin C.P., Avila J., and Moreno F.J. Quinones facilitate the self-assembly of the phosphorylated tubulin binding region of tau into fibrillar polymers. Biochemistry 43 (2004) 2888-2897
-
(2004)
Biochemistry
, vol.43
, pp. 2888-2897
-
-
Santa-Maria, I.1
Hernandez, F.2
Martin, C.P.3
Avila, J.4
Moreno, F.J.5
-
30
-
-
1642289188
-
Role of tau protein in both physiological and pathological conditions
-
Avila J., Lucas J.J., Perez M., and Hernandez F. Role of tau protein in both physiological and pathological conditions. Physiol. Rev. 84 (2004) 361-384
-
(2004)
Physiol. Rev.
, vol.84
, pp. 361-384
-
-
Avila, J.1
Lucas, J.J.2
Perez, M.3
Hernandez, F.4
-
31
-
-
0024745894
-
Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease
-
Goedert M., Spillantini M.G., Jakes R., Rutherford D., and Crowther R.A. Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 3 (1989) 519-526
-
(1989)
Neuron
, vol.3
, pp. 519-526
-
-
Goedert, M.1
Spillantini, M.G.2
Jakes, R.3
Rutherford, D.4
Crowther, R.A.5
-
32
-
-
0024498630
-
Structure of the bovine tau gene: alternatively spliced transcripts generate a protein family
-
Himmler A. Structure of the bovine tau gene: alternatively spliced transcripts generate a protein family. Mol. Cell. Biol. 9 (1989) 1389-1396
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 1389-1396
-
-
Himmler, A.1
-
33
-
-
0003986552
-
Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease
-
Wischik C.M., Novak M., Thogersen H.C., Edwards P.C., Runswick M.J., Jakes R., Walker J.E., Milstein C., Roth M., and Klug A. Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease. Proc. Natl. Acad. Sci. U. S. A. 85 (1988) 4506-4510
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 4506-4510
-
-
Wischik, C.M.1
Novak, M.2
Thogersen, H.C.3
Edwards, P.C.4
Runswick, M.J.5
Jakes, R.6
Walker, J.E.7
Milstein, C.8
Roth, M.9
Klug, A.10
-
34
-
-
0023905288
-
The primary structure and heterogeneity of tau protein from mouse brain
-
Lee G., Cowan N., and Kirschner M. The primary structure and heterogeneity of tau protein from mouse brain. Science 239 (1988) 285-288
-
(1988)
Science
, vol.239
, pp. 285-288
-
-
Lee, G.1
Cowan, N.2
Kirschner, M.3
-
35
-
-
0026595846
-
Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms
-
Goedert M., Spillantini M.G., Cairns N.J., and Crowther R.A. Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms. Neuron 8 (1992) 159-168
-
(1992)
Neuron
, vol.8
, pp. 159-168
-
-
Goedert, M.1
Spillantini, M.G.2
Cairns, N.J.3
Crowther, R.A.4
-
36
-
-
0343831898
-
In vitro assembly of tau protein: mapping the regions involved in filament formation
-
Perez M., Arrasate M., Montejo De Garcini E., Munoz V., and Avila J. In vitro assembly of tau protein: mapping the regions involved in filament formation. Biochemistry 40 (2001) 5983-5991
-
(2001)
Biochemistry
, vol.40
, pp. 5983-5991
-
-
Perez, M.1
Arrasate, M.2
Montejo De Garcini, E.3
Munoz, V.4
Avila, J.5
-
37
-
-
0028121105
-
Assembly of Alzheimer-like filaments from full-length tau protein
-
Crowther R.A., Olesen O.F., Smith M.J., Jakes R., and Goedert M. Assembly of Alzheimer-like filaments from full-length tau protein. FEBS Lett. 337 (1994) 135-138
-
(1994)
FEBS Lett.
, vol.337
, pp. 135-138
-
-
Crowther, R.A.1
Olesen, O.F.2
Smith, M.J.3
Jakes, R.4
Goedert, M.5
-
38
-
-
0031561732
-
The zeta isozyme of protein kinase C binds to tubulin through the pseudosubstrate domain
-
Garcia-Rocha M., Avila J., and Lozano J. The zeta isozyme of protein kinase C binds to tubulin through the pseudosubstrate domain. Exp. Cell Res. 230 (1997) 1-8
-
(1997)
Exp. Cell Res.
, vol.230
, pp. 1-8
-
-
Garcia-Rocha, M.1
Avila, J.2
Lozano, J.3
-
39
-
-
85012367300
-
Influence of the centrosome on the structure of nucleated microtubules
-
Evans L., Mitchison T., and Kirschner M. Influence of the centrosome on the structure of nucleated microtubules. J. Cell Biol. 100 (1985) 1185-1191
-
(1985)
J. Cell Biol.
, vol.100
, pp. 1185-1191
-
-
Evans, L.1
Mitchison, T.2
Kirschner, M.3
-
40
-
-
33746781174
-
Characteristics of the binding of thioflavin S to tau paired helical filaments
-
Santa-Maria I., Perez M., Hernandez F., Avila J., and Moreno F.J. Characteristics of the binding of thioflavin S to tau paired helical filaments. J. Alzheimer's Dis. 9 (2006) 1-7
-
(2006)
J. Alzheimer's Dis.
, vol.9
, pp. 1-7
-
-
Santa-Maria, I.1
Perez, M.2
Hernandez, F.3
Avila, J.4
Moreno, F.J.5
-
41
-
-
0026755755
-
Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro
-
Wille H., Drewes G., Biernat J., Mandelkow E.M., and Mandelkow E. Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro. J. Cell Biol. 118 (1992) 573-584
-
(1992)
J. Cell Biol.
, vol.118
, pp. 573-584
-
-
Wille, H.1
Drewes, G.2
Biernat, J.3
Mandelkow, E.M.4
Mandelkow, E.5
-
42
-
-
0345561533
-
Polymerization of tau peptides into fibrillar structures. The effect of FTDP-17 mutations
-
Arrasate M., Perez M., Armas-Portela R., and Avila J. Polymerization of tau peptides into fibrillar structures. The effect of FTDP-17 mutations. FEBS Lett. 446 (1999) 199-202
-
(1999)
FEBS Lett.
, vol.446
, pp. 199-202
-
-
Arrasate, M.1
Perez, M.2
Armas-Portela, R.3
Avila, J.4
-
44
-
-
0034625060
-
Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure
-
von Bergen M., Friedhoff P., Biernat J., Heberle J., Mandelkow E.M., and Mandelkow E. Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 5129-5134
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 5129-5134
-
-
von Bergen, M.1
Friedhoff, P.2
Biernat, J.3
Heberle, J.4
Mandelkow, E.M.5
Mandelkow, E.6
-
45
-
-
20444403757
-
Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases
-
Pawar A.P., Dubay K.F., Zurdo J., Chiti F., Vendruscolo M., and Dobson C.M. Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases. J. Mol. Biol. 350 (2005) 379-392
-
(2005)
J. Mol. Biol.
, vol.350
, pp. 379-392
-
-
Pawar, A.P.1
Dubay, K.F.2
Zurdo, J.3
Chiti, F.4
Vendruscolo, M.5
Dobson, C.M.6
-
46
-
-
3042602456
-
The formation of straight and twisted filaments from short tau peptides
-
Goux W.J., Kopplin L., Nguyen A.D., Leak K., Rutkofsky M., Shanmuganandam V.D., Sharma D., Inouye H., and Kirschner D.A. The formation of straight and twisted filaments from short tau peptides. J. Biol. Chem. 279 (2004) 26868-26875
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26868-26875
-
-
Goux, W.J.1
Kopplin, L.2
Nguyen, A.D.3
Leak, K.4
Rutkofsky, M.5
Shanmuganandam, V.D.6
Sharma, D.7
Inouye, H.8
Kirschner, D.A.9
-
47
-
-
0347594304
-
Modeling tau polymerization in vitro: a review and synthesis
-
Gamblin T.C., Berry R.W., and Binder L.I. Modeling tau polymerization in vitro: a review and synthesis. Biochemistry 42 (2003) 15009-15017
-
(2003)
Biochemistry
, vol.42
, pp. 15009-15017
-
-
Gamblin, T.C.1
Berry, R.W.2
Binder, L.I.3
|