-
1
-
-
0026740795
-
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
-
Arriagada PV, Growdon JH, Hedley-Whyte ET, Hyman BT (1992) Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 42: 631-639
-
(1992)
Neurology
, vol.42
, pp. 631-639
-
-
Arriagada, P.V.1
Growdon, J.H.2
Hedley-Whyte, E.T.3
Hyman, B.T.4
-
2
-
-
0024587074
-
Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease
-
Bancher C, Brunner C, Lassmann H, Budka H, Jellinger K, Wiche G, Seitelberger F, Grundke-Iqbal Y, Iqbal K, Wisniewski HM (1988) Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease. Brain Res 477:90-99
-
(1988)
Brain Res
, vol.477
, pp. 90-99
-
-
Bancher, C.1
Brunner, C.2
Lassmann, H.3
Budka, H.4
Jellinger, K.5
Wiche, G.6
Seitelberger, F.7
Grundke-Iqbal, Y.8
Iqbal, K.9
Wisniewski, H.M.10
-
3
-
-
0028861585
-
Neocortical neurofibrillary tangles correlate with dementia severity in Alzeimer's disease
-
Bierer LM, Hof PR, Purohit DP, Carlin L, Schmeidler J, Davies KL, Perl DP (1995) Neocortical neurofibrillary tangles correlate with dementia severity in Alzeimer's disease. Arch Neurol 52:81-88
-
(1995)
Arch Neurol
, vol.52
, pp. 81-88
-
-
Bierer, L.M.1
Hof, P.R.2
Purohit, D.P.3
Carlin, L.4
Schmeidler, J.5
Davies, K.L.6
Perl, D.P.7
-
4
-
-
0026551711
-
The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region
-
Biernat JM, Mandelkow EM, Schröter C, Lichtenberg-Kraag B, Steiner B, Berling B, Meyer H, Mercken M, Vandermeeren A, Goedert M, Mandelkow E (1992) The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region. EMBO J 11:1593-1597
-
(1992)
EMBO J
, vol.11
, pp. 1593-1597
-
-
Biernat, J.M.1
Mandelkow, E.M.2
Schröter, C.3
Lichtenberg-Kraag, B.4
Steiner, B.5
Berling, B.6
Meyer, H.7
Mercken, M.8
Vandermeeren, A.9
Goedert, M.10
Mandelkow, E.11
-
5
-
-
0027316077
-
Neurofibrillary tangle densities in the hippocampal formation in a non-demented population define subgroups of patients with differential early pathologic changes
-
Bouras C, Hof PR, Morrison HJ (1993) Neurofibrillary tangle densities in the hippocampal formation in a non-demented population define subgroups of patients with differential early pathologic changes. Neurosci Lett 153:131-135
-
(1993)
Neurosci Lett
, vol.153
, pp. 131-135
-
-
Bouras, C.1
Hof, P.R.2
Morrison, H.J.3
-
6
-
-
0028213511
-
Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of elderly patients: A quantitative evaluation of one-year autopsy population from a geriatric hospital
-
Bouras C, Hof PR, Giannakopoulos P, Michel JP, Morrison JH (1994) Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of elderly patients: A quantitative evaluation of one-year autopsy population from a geriatric hospital. Cereb Cortex 4:138-150
-
(1994)
Cereb Cortex
, vol.4
, pp. 138-150
-
-
Bouras, C.1
Hof, P.R.2
Giannakopoulos, P.3
Michel, J.P.4
Morrison, J.H.5
-
7
-
-
0028362458
-
A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads
-
Braak E, Braak H, Mandelkow EM (1994) A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads. Acta Neuropathol 87:554-567
-
(1994)
Acta Neuropathol
, vol.87
, pp. 554-567
-
-
Braak, E.1
Braak, H.2
Mandelkow, E.M.3
-
8
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82:239-259
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
10
-
-
0028918383
-
Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer's disease
-
Cras P, Smith MA, Richey PL, Siedlak SL, Mulvihill P, Perry G (1995) Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer's disease. Acta Neuropathol 89:291-295
-
(1995)
Acta Neuropathol
, vol.89
, pp. 291-295
-
-
Cras, P.1
Smith, M.A.2
Richey, P.L.3
Siedlak, S.L.4
Mulvihill, P.5
Perry, G.6
-
11
-
-
0027432101
-
Pathological markers associated with normal aging and dementia in the elderly
-
Crystal HA, Dickson DW, Sliwinksi MJ, Lipton RB, Grober E, Marks-Nelson H, Antis P (1993) Pathological markers associated with normal aging and dementia in the elderly. Ann Neurol 34:566-573
-
(1993)
Ann Neurol
, vol.34
, pp. 566-573
-
-
Crystal, H.A.1
Dickson, D.W.2
Sliwinksi, M.J.3
Lipton, R.B.4
Grober, E.5
Marks-Nelson, H.6
Antis, P.7
-
12
-
-
0025284610
-
Pathological proteins Tau 64 and 69 are specifically expressed in the somatodendritic domain of the degenerating cortical neurons during Alzheimer's disease
-
Delacourte A, Flament S, Dibe EM, Hublau P, Sablonniere B, Hemon B, Scherrer V, DeFossez A (1990) Pathological proteins Tau 64 and 69 are specifically expressed in the somatodendritic domain of the degenerating cortical neurons during Alzheimer's disease. Acta Neuropathol 80:111-117
-
(1990)
Acta Neuropathol
, vol.80
, pp. 111-117
-
-
Delacourte, A.1
Flament, S.2
Dibe, E.M.3
Hublau, P.4
Sablonniere, B.5
Hemon, B.6
Scherrer, V.7
DeFossez, A.8
-
13
-
-
0027410176
-
βA4 deposits are constant in the brain of the oldest old: An immunocytochemical study of 20 French centenarians
-
Delaère P, He Y, Fayet G, Duyckaerts C, Hauw JJ ( 1993) βA4 deposits are constant in the brain of the oldest old: an immunocytochemical study of 20 French centenarians. Neurobiol Aging 14:191-194
-
(1993)
Neurobiol Aging
, vol.14
, pp. 191-194
-
-
Delaère, P.1
He, Y.2
Fayet, G.3
Duyckaerts, C.4
Hauw, J.J.5
-
14
-
-
0028344126
-
Neuropathology of 20 centenarians. I. Clinical data
-
Paris
-
Fayet G, Hauw JJ, Delaère P, He Y, Duyckaerts C, Beck H, Forette F, Gallinari C, Laurent M, Moulias R, Piette F, Sachet A (1994) Neuropathology of 20 centenarians. I. Clinical data. Rev Neurol (Paris) 150: 16-21
-
(1994)
Rev Neurol
, vol.150
, pp. 16-21
-
-
Fayet, G.1
Hauw, J.J.2
Delaère, P.3
He, Y.4
Duyckaerts, C.5
Beck, H.6
Forette, F.7
Gallinari, C.8
Laurent, M.9
Moulias, R.10
Piette, F.11
Sachet, A.12
-
15
-
-
0024468551
-
Characterization of two pathological tau protein variants in Alzheimer brain cortices
-
Flament S, DeLacourte A, Hemon B, DeFossez A (1989) Characterization of two pathological tau protein variants in Alzheimer brain cortices. J Neurol Sci 92:133-141
-
(1989)
J Neurol Sci
, vol.92
, pp. 133-141
-
-
Flament, S.1
DeLacourte, A.2
Hemon, B.3
DeFossez, A.4
-
16
-
-
0001152077
-
Braak stages III-IV of Alzheimer-related neuropathology are associated with mild memory loss, stages V-VI are associated with dementia: Findings from the Nun Study
-
Geddes JW, Snowdon DA, Soultanian NS, Tekirian KP, Riley JW, Davis DG, Markesbery WR (1996) Braak stages III-IV of Alzheimer-related neuropathology are associated with mild memory loss, stages V-VI are associated with dementia: findings from the Nun Study. J Neuropathol Exp Neurol 55:617
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, pp. 617
-
-
Geddes, J.W.1
Snowdon, D.A.2
Soultanian, N.S.3
Tekirian, K.P.4
Riley, J.W.5
Davis, D.G.6
Markesbery, W.R.7
-
17
-
-
0028286971
-
Neuropathological changes in the cerebral cortex of 1258 cases from a geriatric hospital: Retrospective clinico-pathological evaluation of a 10-year autopsy population
-
Giannakopoulos P, Hof PR, Mottier S, Michel JP, Bouras C (1994) Neuropathological changes in the cerebral cortex of 1258 cases from a geriatric hospital: retrospective clinico-pathological evaluation of a 10-year autopsy population. Acta Neuropathol 87:456-468
-
(1994)
Acta Neuropathol
, vol.87
, pp. 456-468
-
-
Giannakopoulos, P.1
Hof, P.R.2
Mottier, S.3
Michel, J.P.4
Bouras, C.5
-
18
-
-
0029094405
-
Quantitative analysis of neuropathologic changes in the cerebral cortex of centenarians
-
Giannakopoulos P, Hof PR, Vallet PG, Giannakopoulos AS, Charnay Y, Bouras C (1995) Quantitative analysis of neuropathologic changes in the cerebral cortex of centenarians. Prog Neuropsychopharmacol Biol Psychiatry 19:577-592
-
(1995)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.19
, pp. 577-592
-
-
Giannakopoulos, P.1
Hof, P.R.2
Vallet, P.G.3
Giannakopoulos, A.S.4
Charnay, Y.5
Bouras, C.6
-
19
-
-
0028884524
-
Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of very old patients
-
Giannakopoulos P, Hof PR, Giannakopoulos AS, Herrmann FR, Michel JP, Bouras C (1995) Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of very old patients. Arch Neurol 52:1150-1159
-
(1995)
Arch Neurol
, vol.52
, pp. 1150-1159
-
-
Giannakopoulos, P.1
Hof, P.R.2
Giannakopoulos, A.S.3
Herrmann, F.R.4
Michel, J.P.5
Bouras, C.6
-
20
-
-
0027217679
-
The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer's disease recapitulates phosphorylation during development
-
Goedert M, Jakes R, Crowther RA, Six J, Lübke U, Vandermeeren M, Cras P, Trojanowski JQ, Lee VM-Y (1993) The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer's disease recapitulates phosphorylation during development. Proc Natl Acad Sci USA 90:5066-5070
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 5066-5070
-
-
Goedert, M.1
Jakes, R.2
Crowther, R.A.3
Six, J.4
Lübke, U.5
Vandermeeren, M.6
Cras, P.7
Trojanowski, J.Q.8
Lee, V.M.-Y.9
-
21
-
-
0028946744
-
Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205
-
Goedert M, Jakes R, Vanmechelen E (1995) Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205. Neurosci Lett 189: 167-169
-
(1995)
Neurosci Lett
, vol.189
, pp. 167-169
-
-
Goedert, M.1
Jakes, R.2
Vanmechelen, E.3
-
22
-
-
0029979798
-
Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease
-
Gómez-Isla T, Price JL, McKeel DW, Morris JC, Growdon JH, Hyman BT (1996) Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease. J Neurosci 16: 4491-4500
-
(1996)
J Neurosci
, vol.16
, pp. 4491-4500
-
-
Gómez-Isla, T.1
Price, J.L.2
McKeel, D.W.3
Morris, J.C.4
Growdon, J.H.5
Hyman, B.T.6
-
23
-
-
0344653664
-
Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease
-
Gómez-Isla T, Hollister R, West H, Mui S, Growdon JH, Petersen RC, Parisi JE, Hyman BT (1997) Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease. Ann Neurol 41:17-24
-
(1997)
Ann Neurol
, vol.41
, pp. 17-24
-
-
Gómez-Isla, T.1
Hollister, R.2
West, H.3
Mui, S.4
Growdon, J.H.5
Petersen, R.C.6
Parisi, J.E.7
Hyman, B.T.8
-
24
-
-
0022522889
-
Neuropathological study of 12 centenarians: The incidence of Alzheimer type senile dementia is not particularly increased in this group of very old patients
-
Paris
-
Hauw JJ, Vignolo P, Duyckaerts C, Beck H, Forette F, Henry JF, Laurent M, Piette F, Sachet A, Berthaux P (1986) Neuropathological study of 12 centenarians: the incidence of Alzheimer type senile dementia is not particularly increased in this group of very old patients. Rev Neurol (Paris) 142: 107-115
-
(1986)
Rev Neurol
, vol.142
, pp. 107-115
-
-
Hauw, J.J.1
Vignolo, P.2
Duyckaerts, C.3
Beck, H.4
Forette, F.5
Henry, J.F.6
Laurent, M.7
Piette, F.8
Sachet, A.9
Berthaux, P.10
-
25
-
-
0032522508
-
An immunohistochemical study of centenarian brains: A comparison
-
Itoh Y, Yamada M, Suematsu N, Matsushita M, Otomo E (1998) An immunohistochemical study of centenarian brains: a comparison. J Neurol Sci 157:73-81
-
(1998)
J Neurol Sci
, vol.157
, pp. 73-81
-
-
Itoh, Y.1
Yamada, M.2
Suematsu, N.3
Matsushita, M.4
Otomo, E.5
-
26
-
-
0023905906
-
Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques
-
Katzman R, Terry R, DeTeresa R, Brown T, Davies P, Fuld P, Renbing X, Peck A (1988) Clinical, pathological, and neurochemical changes in dementia: a subgroup with preserved mental status and numerous neocortical plaques. Ann Neurol 23: 138-144
-
(1988)
Ann Neurol
, vol.23
, pp. 138-144
-
-
Katzman, R.1
Terry, R.2
Deteresa, R.3
Brown, T.4
Davies, P.5
Fuld, P.6
Renbing, X.7
Peck, A.8
-
27
-
-
0027244630
-
Clinicopathologic correlates in Alzheimer's disease: Assessment of clinical and pathologic diagnostic criteria
-
Kazze AM, Eskin TA, Lapham LW, Gabriel KR, McDaniel KD, Hamill RW (1993) Clinicopathologic correlates in Alzheimer's disease: assessment of clinical and pathologic diagnostic criteria. Alzheimer Dis Assoc Disord 7: 152-164
-
(1993)
Alzheimer Dis Assoc Disord
, vol.7
, pp. 152-164
-
-
Kazze, A.M.1
Eskin, T.A.2
Lapham, L.W.3
Gabriel, K.R.4
McDaniel, K.D.5
Hamill, R.W.6
-
28
-
-
0025904444
-
A68: A major subunit of paired helical filaments and derivatized forms of normal tau
-
Lee VMY, Balin BJ, Otvos L, Trojanowski JQ (1991) A68: a major subunit of paired helical filaments and derivatized forms of normal tau. Science 251:675-678
-
(1991)
Science
, vol.251
, pp. 675-678
-
-
Lee, V.M.Y.1
Balin, B.J.2
Otvos, L.3
Trojanowski, J.Q.4
-
29
-
-
0023225114
-
The topographic distribution of senile plaques and neurofibrillary tangles in the brains of non-demented persons of different ages
-
Mann DMA, Tucker CM, Yates PO (1987) The topographic distribution of senile plaques and neurofibrillary tangles in the brains of non-demented persons of different ages. Neuropathol Appl Neurobiol 13:123-139
-
(1987)
Neuropathol Appl Neurobiol
, vol.13
, pp. 123-139
-
-
Mann, D.M.A.1
Tucker, C.M.2
Yates, P.O.3
-
30
-
-
0028798197
-
Monitoring pathological assembly of tau and β-amyloid proteins in Alzheimer's disease
-
Mena R, Edwards P, Pérez-Olvera O, Wischik CM (1995) Monitoring pathological assembly of tau and β-amyloid proteins in Alzheimer's disease. Acta Neuropathol 89:50-56
-
(1995)
Acta Neuropathol
, vol.89
, pp. 50-56
-
-
Mena, R.1
Edwards, P.2
Pérez-Olvera, O.3
Wischik, C.M.4
-
31
-
-
0029997922
-
Staging the pathological assembly of tau protein into paired helical filaments in Alzheimer's disease
-
Mena R, Edwards P, Harrington CR, Mukaetova-Ladinska EB, Wischik CM (1996) Staging the pathological assembly of tau protein into paired helical filaments in Alzheimer's disease. Acta Neuropathol 91:633-641
-
(1996)
Acta Neuropathol
, vol.91
, pp. 633-641
-
-
Mena, R.1
Edwards, P.2
Harrington, C.R.3
Mukaetova-Ladinska, E.B.4
Wischik, C.M.5
-
32
-
-
0029892175
-
Cerebral amyloid deposition and diffuse plaques in "normal" aging: Evidence for presymptomatic and very mild Alzheimer's disease
-
Morris JC, Storandt M, McKeel DW, Rubin EH, Price JL, Grant EA, Berg L (1996) Cerebral amyloid deposition and diffuse plaques in "normal" aging: evidence for presymptomatic and very mild Alzheimer's disease. Neurology 46:707-719
-
(1996)
Neurology
, vol.46
, pp. 707-719
-
-
Morris, J.C.1
Storandt, M.2
McKeel, D.W.3
Rubin, E.H.4
Price, J.L.5
Grant, E.A.6
Berg, L.7
-
34
-
-
0028831582
-
Relative roles of plaques and tangles in the dementia of Alzheimer's disease: Correlations using three sets of neuropathological criteria
-
Nagy ZS, Esiri MM, Jobst KA, Morris JH, King EMF, McDonald B, Litchfield S, Smith A, Barnetson L, Smith AD (1995) Relative roles of plaques and tangles in the dementia of Alzheimer's disease: correlations using three sets of neuropathological criteria. Dementia 6:21-31
-
(1995)
Dementia
, vol.6
, pp. 21-31
-
-
Nagy, Z.S.1
Esiri, M.M.2
Jobst, K.A.3
Morris, J.H.4
King, E.M.F.5
McDonald, B.6
Litchfield, S.7
Smith, A.8
Barnetson, L.9
Smith, A.D.10
-
35
-
-
0027398169
-
Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filaments
-
Novak M, Kabat J, Wischik CM (1993) Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filaments. EMBO J 12:365-370
-
(1993)
EMBO J
, vol.12
, pp. 365-370
-
-
Novak, M.1
Kabat, J.2
Wischik, C.M.3
-
36
-
-
0345512210
-
Anatomical correlates of the distribution of the pathological changes in the neocortex in AD
-
Pearson RCA, Esiri MM, Hiorns RW, Wilcock GK, Powell TPS (1985) Anatomical correlates of the distribution of the pathological changes in the neocortex in AD. Proc Natl Acad Sci USA 82:4531-4534
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 4531-4534
-
-
Pearson, R.C.A.1
Esiri, M.M.2
Hiorns, R.W.3
Wilcock, G.K.4
Powell, T.P.S.5
-
37
-
-
0343355707
-
Neuropathological findings in cognitively normal older adults
-
Schmitt FA, Wekstein DR, Davies D, Beuscher A, Markesbery WR (1994) Neuropathological findings in cognitively normal older adults. Neurobiol Aging 15: S 109-S 110
-
(1994)
Neurobiol Aging
, vol.15
-
-
Schmitt, F.A.1
Wekstein, D.R.2
Davies, D.3
Beuscher, A.4
Markesbery, W.R.5
-
38
-
-
0014326852
-
Observations on the brains of non-demented old people
-
Tomilson BE, Blessed G, Roth M (1968) Observations on the brains of non-demented old people. J Neurol Sci 7:331-356
-
(1968)
J Neurol Sci
, vol.7
, pp. 331-356
-
-
Tomilson, B.E.1
Blessed, G.2
Roth, M.3
-
39
-
-
0028828408
-
Cortical mapping of Alzheimer pathology in brains of aged non-demented subjects
-
Vermersch P, David JP, Frigard B, Fallet-Bianco C, Wattez A, Petit H, Delacourte A (1995 b) Cortical mapping of Alzheimer pathology in brains of aged non-demented subjects. Prog Neuropsychopharmacol Biol Psychiatry 19:1035-1047
-
(1995)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.19
, pp. 1035-1047
-
-
Vermersch, P.1
David, J.P.2
Frigard, B.3
Fallet-Bianco, C.4
Wattez, A.5
Petit, H.6
Delacourte, A.7
|