Cooexpression of FTDP-17 tau and GSK-3β in transgenic mice induce tau polymerization and neurodegeneration

Neurobiology of Aging

Volumn 27, Issue 9, 2006, Pages 1258-1268

  Engel, Tobias ^a   Lucas, José J ^a   Gómez Ramos, Pilar ^a   Moran, María A ^a   Ávila, Jesús ^a   Hernández, Félix ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Alzheimer's disease; FTDP 17; GSK 3; Paired helical filaments; Tau; Transgenic mice

Indexed keywords

DIRECT YELLOW 7; GLYCOGEN SYNTHASE KINASE 3BETA; TAU PROTEIN; THIOFLAVINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BRAIN ATROPHY; BRAIN NERVE CELL; CHEMICAL ANALYSIS; CONTROLLED STUDY; DENTATE GYRUS; FRONTOTEMPORAL DEMENTIA WITH PARKINSONISM ASSOCIATED TO CHROMOSOME 17; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MORPHOLOGY; MOUSE; NERVE DEGENERATION; NEUROCHEMISTRY; NEUROPATHOLOGY; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN POLYMERIZATION; TAUOPATHY; TRANSGENIC MOUSE;

ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; DENTATE GYRUS; GLYCOGEN SYNTHASE KINASE 3; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; NERVE DEGENERATION; NEUROFILAMENT PROTEINS; PHOSPHORYLATION; TAU PROTEINS; THIAZOLES;

EID: 33746210131     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2005.06.010     Document Type: Article

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