메뉴 건너뛰기




Volumn 4, Issue 2, 2008, Pages 110-121

Candidate genes implicated in type 1 diabetes suceptibility

Author keywords

Candidate genes; Identification strategies; Type 1 diabetes susceptibility

Indexed keywords

AUTOANTIBODY; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; GLUTAMATE DECARBOXYLASE 65 ANTIBODY; GLUTAMATE DECARBOXYLASE ANTIBODY; HEAT SHOCK PROTEIN; HLA A ANTIGEN; HLA ANTIGEN; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; HLA DR ANTIGEN; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INSULIN ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; LYMPHOTOXIN; MACROPHAGE MIGRATION INHIBITION FACTOR; PANCREAS ISLET CELL ANTIBODY; SUMO 4 PROTEIN; SUMO PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 48749132434     PISSN: 15733998     EISSN: None     Source Type: Journal    
DOI: 10.2174/157339908784220723     Document Type: Review
Times cited : (18)

References (151)
  • 1
    • 1842334456 scopus 로고    scopus 로고
    • Report ofthe expert committee on the diagnosis and classification of diabetes mellitus
    • American Diabetes Association
    • American Diabetes Association. Report ofthe expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 1997; 20: 1183-97.
    • (1997) Diabetes Care , vol.20 , pp. 1183-1197
  • 2
    • 0030783140 scopus 로고    scopus 로고
    • Diabète insulino-dépendaht: Etiologie, physiopathologie, diagnostic, complications, pronostic, traitement
    • Bourcigaux N, Charbonnel B. Diabète insulino-dépendaht: Etiologie, physiopathologie, diagnostic, complications, pronostic, traitement. Rev Prat. 1997; 47: 1583-92.
    • (1997) Rev Prat , vol.47 , pp. 1583-1592
    • Bourcigaux, N.1    Charbonnel, B.2
  • 4
    • 0033429304 scopus 로고    scopus 로고
    • Worldwide increase in incidence of type I diabetes: The analysis of the data on published incidence trends
    • Onkamo P, Väänänen S, Karvonen M, Tuomilehto J. Worldwide increase in incidence of type I diabetes: the analysis of the data on published incidence trends. Diabetologia 1999; 42: 1395-403.
    • (1999) Diabetologia , vol.42 , pp. 1395-1403
    • Onkamo, P.1    Väänänen, S.2    Karvonen, M.3    Tuomilehto, J.4
  • 5
    • 0027990934 scopus 로고
    • Incidence of insulin-dependent diabetes mellitus in age groups over 30 years in Denmark
    • Molbak AG, Christau B, Mamer B, Borch-Johnsen K, Nerup J. Incidence of insulin-dependent diabetes mellitus in age groups over 30 years in Denmark. Diabet Med 1994; 11: 650-5.
    • (1994) Diabet Med , vol.11 , pp. 650-655
    • Molbak, A.G.1    Christau, B.2    Mamer, B.3    Borch-Johnsen, K.4    Nerup, J.5
  • 6
    • 0033178614 scopus 로고    scopus 로고
    • IL-18 inhibits diabetes development in non-obese diabetic mice by counterregulation of Th1-dependent destructive insulitis
    • Rothe H, Haussmmann A, Casteels K, el al. IL-18 inhibits diabetes development in non-obese diabetic mice by counterregulation of Th1-dependent destructive insulitis. J immunol 1999; 163: 1230-6.
    • (1999) J immunol , vol.163 , pp. 1230-1236
    • Rothe, H.1    Haussmmann, A.2    Casteels, K.3    el al4
  • 7
    • 0141995527 scopus 로고    scopus 로고
    • Serum IL-1, IL-2, TNF-α and IFN-γ levels of patients with type 1 diabetes mellitus and their siblings
    • Özer G, Teker Z, Cetiner S, et al. Serum IL-1, IL-2, TNF-α and IFN-γ levels of patients with type 1 diabetes mellitus and their siblings. J Pediatr Fndocrinol Metab 2003; 16: 203-10.
    • (2003) J Pediatr Fndocrinol Metab , vol.16 , pp. 203-210
    • Özer, G.1    Teker, Z.2    Cetiner, S.3
  • 8
    • 0035714595 scopus 로고    scopus 로고
    • Mediators of inflammation in children with type 1 diabetes mellitus: Cytokines in type 1 diabetic children
    • Erbaǧci AB, Tarakcioglu M, Coskun Y, Sivasli E, Sibel Namiduru E. Mediators of inflammation in children with type 1 diabetes mellitus: cytokines in type 1 diabetic children. Clin Biochem 2001: 34: 645-50.
    • (2001) Clin Biochem , vol.34 , pp. 645-650
    • Erbaǧci, A.B.1    Tarakcioglu, M.2    Coskun, Y.3    Sivasli, E.4    Sibel Namiduru, E.5
  • 9
    • 0032518421 scopus 로고    scopus 로고
    • Prediction of insulin-dependent diabetes mellitus in siblings of children with diabetes. A population-based study. The Childhood Diabetes in Finland Study Group
    • Kulmala P, Savola K, Petersen JS, et al. Prediction of insulin-dependent diabetes mellitus in siblings of children with diabetes. A population-based study. The Childhood Diabetes in Finland Study Group. J Clin Invest 1998; 101: 327-36.
    • (1998) J Clin Invest , vol.101 , pp. 327-336
    • Kulmala, P.1    Savola, K.2    Petersen, J.S.3
  • 10
    • 0031962147 scopus 로고    scopus 로고
    • Increased prevalence of abnormal immunoglobulin M, G, and A concentrations at clinical onset of insulin-dependent diabetes mellitus: A registry-based study. The Belgian Diabetes Registry
    • Gorus FK, Vandewalle CL, Winnock F, et al. Increased prevalence of abnormal immunoglobulin M, G, and A concentrations at clinical onset of insulin-dependent diabetes mellitus: a registry-based study. The Belgian Diabetes Registry. Pancreas 1998; 16: 50-9.
    • (1998) Pancreas , vol.16 , pp. 50-59
    • Gorus, F.K.1    Vandewalle, C.L.2    Winnock, F.3
  • 12
    • 0024155365 scopus 로고
    • HLA disease associations: Models for insulin dependent diabetes mellitus and the study of complex human genetic disorders
    • Thomson G. HLA disease associations: models for insulin dependent diabetes mellitus and the study of complex human genetic disorders. Annu Rev Genet 1988; 22: 31-50.
    • (1988) Annu Rev Genet , vol.22 , pp. 31-50
    • Thomson, G.1
  • 13
    • 0026077831 scopus 로고
    • Genetic analysis of a complex, multifactorial disease, autoimmune type 1 (insulin-dependent) diabetes
    • Todd JA, Aitman TJ, Comall RJ, et al. Genetic analysis of a complex, multifactorial disease, autoimmune type 1 (insulin-dependent) diabetes. Res Immunol 1991; 142: 483.
    • (1991) Res Immunol , vol.142 , pp. 483
    • Todd, J.A.1    Aitman, T.J.2    Comall, R.J.3
  • 14
    • 0026794517 scopus 로고
    • A practical approach to identification of susceptibility genes for IDDM
    • Todd JA, Bain SC. A practical approach to identification of susceptibility genes for IDDM. Diabetes 1992; 41: 1029-34.
    • (1992) Diabetes , vol.41 , pp. 1029-1034
    • Todd, J.A.1    Bain, S.C.2
  • 15
    • 0026697932 scopus 로고
    • Life table analysis of the risk of type 1 (insulin-dependent) diabetes mellitus in siblings according to islet cell antibodies and HLA markers: An 8-year prospective study
    • Deschamps I, Boitard C, Hors J, et al. Life table analysis of the risk of type 1 (insulin-dependent) diabetes mellitus in siblings according to islet cell antibodies and HLA markers: an 8-year prospective study. Diabetologia 1992; 35: 951-7.
    • (1992) Diabetologia , vol.35 , pp. 951-957
    • Deschamps, I.1    Boitard, C.2    Hors, J.3
  • 16
    • 1642443489 scopus 로고    scopus 로고
    • Type 1 diabetes: Recent developments
    • Devendra D, Liu E, Eisenbarth GS. Type 1 diabetes: recent developments. BMJ 2004; 328: 750-4.
    • (2004) BMJ , vol.328 , pp. 750-754
    • Devendra, D.1    Liu, E.2    Eisenbarth, G.S.3
  • 17
    • 9644280863 scopus 로고    scopus 로고
    • Age-Dependent Influences on the Origins of Autoimmune Diabetes. Evidence and Implications
    • Leslie RDG, Delli Castelli M. Age-Dependent Influences on the Origins of Autoimmune Diabetes. Evidence and Implications. Diabetes 2004; 53: 3033-40.
    • (2004) Diabetes , vol.53 , pp. 3033-3040
    • Leslie, R.D.G.1    Delli Castelli, M.2
  • 18
    • 0345505676 scopus 로고    scopus 로고
    • Genetic liability of type 1 diabetes and the onset aee amona 22,650 young finnish twin pairs: A nationwide follow-up study
    • Hyttinen V, Kaprio J, Kinnonen L, Koskenvuo M, Tuomilehto J. Genetic liability of type 1 diabetes and the onset aee amona 22,650 young finnish twin pairs: a nationwide follow-up study. Diabetes 2003; 52: 1052-5.
    • (2003) Diabetes , vol.52 , pp. 1052-1055
    • Hyttinen, V.1    Kaprio, J.2    Kinnonen, L.3    Koskenvuo, M.4    Tuomilehto, J.5
  • 19
    • 0035076548 scopus 로고    scopus 로고
    • Heterogeneity of type I diabetes: Analysis of monozygotic twins in Great Britain and the United States
    • Redondo MJ, Yu L, Hawa M, et al. Heterogeneity of type I diabetes: analysis of monozygotic twins in Great Britain and the United States. Diabetologia 2001; 44: 354-62.
    • (2001) Diabetologia , vol.44 , pp. 354-362
    • Redondo, M.J.1    Yu, L.2    Hawa, M.3
  • 20
    • 0027169651 scopus 로고
    • North-American twins with IDDM: Genetic, etiological, and clinical significance of disease concordance according to age, zygosity, and the interval after diagnosis in first twin
    • Kumar D, Gemayel NS, Deapen D, et al. North-American twins with IDDM: genetic, etiological, and clinical significance of disease concordance according to age, zygosity, and the interval after diagnosis in first twin. Diabetes 1993; 42: 1351-63.
    • (1993) Diabetes , vol.42 , pp. 1351-1363
    • Kumar, D.1    Gemayel, N.S.2    Deapen, D.3
  • 22
    • 34347255769 scopus 로고    scopus 로고
    • Writing Group for the SEARCH for Diabetes in Youth Study Group, Dabelea D, Bell RA, et al. Incidence of diabetes in youth in the United States. JAMA 2007; 297: 2716-24. [published erratum appears In JAMA 2007; 298: 627].
    • Writing Group for the SEARCH for Diabetes in Youth Study Group, Dabelea D, Bell RA, et al. Incidence of diabetes in youth in the United States. JAMA 2007; 297: 2716-24. [published erratum appears In JAMA 2007; 298: 627].
  • 23
    • 33750107067 scopus 로고    scopus 로고
    • The burden of diabetes mellitus among US youth: Prevalence estimates from the SEARCH for Diabetes in Youth Study
    • SEARCH for Diabetes in Youth Study Group
    • SEARCH for Diabetes in Youth Study Group, Liese AD, D'Agostino RB Jr, et al. The burden of diabetes mellitus among US youth: prevalence estimates from the SEARCH for Diabetes in Youth Study. Pediatrics 2006; 118: 1510-8.
    • (2006) Pediatrics , vol.118 , pp. 1510-1518
    • Liese, A.D.1    D'Agostino Jr, R.B.2
  • 24
    • 0141615867 scopus 로고    scopus 로고
    • Three-year prevalence and incidence of diabetes among American Indian youth in Montana and Wyoming, 1999 to 2001
    • Moore KR, Harwell TS, McDowall JM, Helgerson SD, Gohdes D. Three-year prevalence and incidence of diabetes among American Indian youth in Montana and Wyoming, 1999 to 2001. J Pediatr 2003; 143: 368-71.
    • (2003) J Pediatr , vol.143 , pp. 368-371
    • Moore, K.R.1    Harwell, T.S.2    McDowall, J.M.3    Helgerson, S.D.4    Gohdes, D.5
  • 25
    • 0022825032 scopus 로고
    • Blood and urinary glucose for optimal control of diabetes in children
    • Robert JJ, Darmaun D, Reach G, Lestradet H. Blood and urinary glucose for optimal control of diabetes in children. Ann Pediatr (Paris) 1986; 33: 904-6.
    • (1986) Ann Pediatr (Paris) , vol.33 , pp. 904-906
    • Robert, J.J.1    Darmaun, D.2    Reach, G.3    Lestradet, H.4
  • 26
    • 0343292719 scopus 로고    scopus 로고
    • Diagnostic des diabètes de l'enfant.
    • Tubiana RN. Diagnostic des diabètes de l'enfant. Rev Prat 1996; 46: 552-5.
    • (1996) Rev Prat , vol.46 , pp. 552-555
    • Tubiana, R.N.1
  • 29
    • 0036164731 scopus 로고    scopus 로고
    • Genetic linkage and association studies of type 1 diabetes: Challenges and rewards
    • Field LL. Genetic linkage and association studies of type 1 diabetes: challenges and rewards. Diabetologia 2002; 45: 21-35.
    • (2002) Diabetologia , vol.45 , pp. 21-35
    • Field, L.L.1
  • 30
    • 0030444451 scopus 로고    scopus 로고
    • Human type 1A diabetes and the insulin gene: Principles of mapping polygenes
    • Bennett ST, Todd JA. Human type 1A diabetes and the insulin gene: principles of mapping polygenes. Annu Rev Genet 1996; 30; 343-70.
    • (1996) Annu Rev Genet , vol.30 , pp. 343-370
    • Bennett, S.T.1    Todd, J.A.2
  • 31
    • 0025995836 scopus 로고
    • Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility
    • Juliet C, Hyer RN, Davies J, et al. Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility. Nature 1991; 354: 155-9.
    • (1991) Nature , vol.354 , pp. 155-159
    • Juliet, C.1    Hyer, R.N.2    Davies, J.3
  • 32
    • 7444253875 scopus 로고    scopus 로고
    • IDDM1 and multiple family history of type 1 diabetes combine to identify neonates at high risk for type 1 diabetes
    • Bonifacio E, Hummel M, Walter M, Schmid S, Ziegler AG. IDDM1 and multiple family history of type 1 diabetes combine to identify neonates at high risk for type 1 diabetes. Diabetes Care 2004; 27: 2695-700.
    • (2004) Diabetes Care , vol.27 , pp. 2695-2700
    • Bonifacio, E.1    Hummel, M.2    Walter, M.3    Schmid, S.4    Ziegler, A.G.5
  • 33
    • 48749114859 scopus 로고    scopus 로고
    • Bach JF. L'origine immunitaire du diabète. Recherche 1989; 214: 1206-15.
    • Bach JF. L'origine immunitaire du diabète. Recherche 1989; 214: 1206-15.
  • 34
    • 34249702823 scopus 로고    scopus 로고
    • The clinical and immumogenetic characteristics of adult-onset type 1 diabetes mellitus in Korea
    • Kim CS, Song MK, Park JS, et al. The clinical and immumogenetic characteristics of adult-onset type 1 diabetes mellitus in Korea. Acta Diabetol 2007; 44: 45-54.
    • (2007) Acta Diabetol , vol.44 , pp. 45-54
    • Kim, C.S.1    Song, M.K.2    Park, J.S.3
  • 35
    • 0032967848 scopus 로고    scopus 로고
    • Horton V, Stratton I, Bottazzo GF, et al. Genetic heterogencity of autoimmune diabetes: age at presentation in adults is influenced by HLA DRB1 and DQB1 genotypes (UKPDS 43). Diabetologia 1999; 42: 608-16.
    • Horton V, Stratton I, Bottazzo GF, et al. Genetic heterogencity of autoimmune diabetes: age at presentation in adults is influenced by HLA DRB1 and DQB1 genotypes (UKPDS 43). Diabetologia 1999; 42: 608-16.
  • 36
    • 0035430208 scopus 로고    scopus 로고
    • Autoimmune diabetes not requiring insulin at diagnosis (latent autoimmune diabetes of the adult): Definition, characterization, and potential prevention
    • Pozzilli P, Di Mario U. Autoimmune diabetes not requiring insulin at diagnosis (latent autoimmune diabetes of the adult): definition, characterization, and potential prevention. Diabetes Care 2001; 24: 1460-7.
    • (2001) Diabetes Care , vol.24 , pp. 1460-1467
    • Pozzilli, P.1    Di Mario, U.2
  • 37
    • 0031560175 scopus 로고    scopus 로고
    • UKPDS 25: Autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes: UK Prospective Diabetes Study Group
    • Turner R, Stratton I, Horton V, et al. UKPDS 25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes: UK Prospective Diabetes Study Group. Lancet 1997; 350: 1288-93.
    • (1997) Lancet , vol.350 , pp. 1288-1293
    • Turner, R.1    Stratton, I.2    Horton, V.3
  • 38
    • 27644546712 scopus 로고    scopus 로고
    • Population structure, differential bias and genomic control in a large-scale, case-control association study
    • Clayton DG, Walker NM, Smyth DJ, et al. Population structure, differential bias and genomic control in a large-scale, case-control association study. Nat Genet 2005; 37: 1243-6.
    • (2005) Nat Genet , vol.37 , pp. 1243-1246
    • Clayton, D.G.1    Walker, N.M.2    Smyth, D.J.3
  • 39
    • 12244297072 scopus 로고    scopus 로고
    • Recombination botspots rather than population history dominate linkage disequilibrium in the MHC class II region
    • Kauppi L, Sajantila A, Jeffreys AJ. Recombination botspots rather than population history dominate linkage disequilibrium in the MHC class II region. Hum Mol Genet 2003; 12: 33-40.
    • (2003) Hum Mol Genet , vol.12 , pp. 33-40
    • Kauppi, L.1    Sajantila, A.2    Jeffreys, A.J.3
  • 40
    • 48749089321 scopus 로고
    • Cavalli-Sforzi LL, Menozzi P, Piazza A Ed, Princeton, Princeton University Press
    • France. In: Cavalli-Sforzi LL, Menozzi P, Piazza A Ed, The history and geography of human genes. Princeton, Princeton University Press. 1993; 280-5.
    • (1993) The history and geography of human genes , pp. 280-285
    • France1
  • 41
    • 48749114348 scopus 로고    scopus 로고
    • Anne Cambon Thomsen, editor. 440. De la génétique des populations à la génétique épidémiologique et à la santé publique. Génétique, Populations et Maladies; 2002 July 19; Université de tous les savoirs, France.
    • Anne Cambon Thomsen, editor. 440. De la génétique des populations à la génétique épidémiologique et à la santé publique. Génétique, Populations et Maladies; 2002 July 19; Université de tous les savoirs, France.
  • 42
    • 0036314246 scopus 로고    scopus 로고
    • A genomewide search for linkage-disequilibrium with type 1 diabetes in a recent genetically isolated population from the Netherlands
    • Vaessen N, Heutink P, Houwing-Duistermaat JJ, et al. A genomewide search for linkage-disequilibrium with type 1 diabetes in a recent genetically isolated population from the Netherlands. Diabetes 2002; 51: 856-9.
    • (2002) Diabetes , vol.51 , pp. 856-859
    • Vaessen, N.1    Heutink, P.2    Houwing-Duistermaat, J.J.3
  • 43
    • 0029128706 scopus 로고
    • Concordance rates of insulin dependent diabetes mellitus: A population based study of young Danish twins
    • Kyvik KO, Green A, Beck-Nielsen H. Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twins. BMJ 1995; 311: 913-7.
    • (1995) BMJ , vol.311 , pp. 913-917
    • Kyvik, K.O.1    Green, A.2    Beck-Nielsen, H.3
  • 44
    • 0026641354 scopus 로고
    • Concordance for type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland
    • Kaprio J, Tuomilehto J, Koskenvuo M, et al. Concordance for type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland. Diabetologia 1992; 35: 1060-7.
    • (1992) Diabetologia , vol.35 , pp. 1060-1067
    • Kaprio, J.1    Tuomilehto, J.2    Koskenvuo, M.3
  • 45
    • 0036097477 scopus 로고    scopus 로고
    • High Familial Risk and Genetic Susceptibility in Early Onset Childhood Diabetes
    • Gillespie KM, Gale EAM, Bingley PJ. High Familial Risk and Genetic Susceptibility in Early Onset Childhood Diabetes. Diabetes 2002; 51: 21-4.
    • (2002) Diabetes , vol.51 , pp. 21-24
    • Gillespie, K.M.1    Gale, E.A.M.2    Bingley, P.J.3
  • 46
    • 0037386030 scopus 로고    scopus 로고
    • Clinical, autoimmune, and HLA characteristics of children diagnosed with type 1 diabetes before 5 years of age
    • Hathout EH, Hartwick N, Fagoaga OR, et al. Clinical, autoimmune, and HLA characteristics of children diagnosed with type 1 diabetes before 5 years of age. Pediatrics 2003; 111: 860-3.
    • (2003) Pediatrics , vol.111 , pp. 860-863
    • Hathout, E.H.1    Hartwick, N.2    Fagoaga, O.R.3
  • 47
    • 0033550904 scopus 로고    scopus 로고
    • Genetic determination of islet cell autoimmunity, in monozygotic twin, dizygotic twin, and non-twin siblings of patients with type 1 diabetes: Prospective twin study
    • Redondo MJ, Rewers M, Yu L, et al. Genetic determination of islet cell autoimmunity, in monozygotic twin, dizygotic twin, and non-twin siblings of patients with type 1 diabetes: prospective twin study. BMJ 1999; 318: 698-702.
    • (1999) BMJ , vol.318 , pp. 698-702
    • Redondo, M.J.1    Rewers, M.2    Yu, L.3
  • 48
    • 0036894289 scopus 로고    scopus 로고
    • Challenges and strategies for investigating the genetic complexity of common human diseases
    • Rich SS, Concannon P. Challenges and strategies for investigating the genetic complexity of common human diseases. Diabetes 2002; 51 (Suppl 3): S288-94.
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 3
    • Rich, S.S.1    Concannon, P.2
  • 49
    • 0033657587 scopus 로고    scopus 로고
    • Caillat-Zucman S. Prix Apollinaire Bouchardat 2000. Approche immunogénétique du diabète de type 1 chez l'homme. J Annu Diabetol Hotel Dieu 2000; 39-51.
    • Caillat-Zucman S. Prix Apollinaire Bouchardat 2000. Approche immunogénétique du diabète de type 1 chez l'homme. J Annu Diabetol Hotel Dieu 2000; 39-51.
  • 50
    • 0043048571 scopus 로고
    • Sequential tests for the detection of linkage
    • Morton NE. Sequential tests for the detection of linkage. Am J Hum Genet 1955; 7: 277-318.
    • (1955) Am J Hum Genet , vol.7 , pp. 277-318
    • Morton, N.E.1
  • 52
    • 0020662969 scopus 로고
    • HLA-DR typing in identical twins with insulin-dependent diabetes: Difference between concordant and discordant pairs
    • Johnston C, Pyke DA, Cudworth AG, Wolf E. HLA-DR typing in identical twins with insulin-dependent diabetes: difference between concordant and discordant pairs. Br Med J 1983; 286: 253-5.
    • (1983) Br Med J , vol.286 , pp. 253-255
    • Johnston, C.1    Pyke, D.A.2    Cudworth, A.G.3    Wolf, E.4
  • 53
    • 4344710134 scopus 로고    scopus 로고
    • Statistics review 11: Assessing risk
    • Viv Bewick, Liz Cheek, Jonathan Ball. Statistics review 11: Assessing risk. Crit Care 2004; 8: 287-91.
    • (2004) Crit Care , vol.8 , pp. 287-291
    • Bewick, V.1    Cheek, L.2    Ball, J.3
  • 54
    • 48749119420 scopus 로고    scopus 로고
    • Vance Berger W, Jialu Zhang. Case-Control Studies. Encyclopedia of Statistics in Behavioral Science. Article Online Posting Date: October 15, 2005. DOI: 10.1002/0470013192,bsa073.
    • Vance Berger W, Jialu Zhang. Case-Control Studies. Encyclopedia of Statistics in Behavioral Science. Article Online Posting Date: October 15, 2005. DOI: 10.1002/0470013192,bsa073.
  • 55
    • 85007758494 scopus 로고    scopus 로고
    • When can odds ratios mislead? Odds ratios should be used only in case-control studies and logistic regression analyses
    • Deeks J. When can odds ratios mislead? Odds ratios should be used only in case-control studies and logistic regression analyses. Br Med J 1998 317: 1155-6.
    • (1998) Br Med J , vol.317 , pp. 1155-1156
    • Deeks, J.1
  • 56
    • 48749125543 scopus 로고    scopus 로고
    • A crash course in stats
    • 4
    • Sue Kirkman M. A crash course in stats. DOC News 2007; 4: 2.
    • (2007) DOC News , pp. 2
    • Sue Kirkman, M.1
  • 57
    • 85007745189 scopus 로고    scopus 로고
    • Statistics notes. The odds ratio
    • Bland JM, Altman DG. Statistics notes. The odds ratio. BMJ 2000; 320: 1468.
    • (2000) BMJ , vol.320 , pp. 1468
    • Bland, J.M.1    Altman, D.G.2
  • 58
    • 0032979261 scopus 로고    scopus 로고
    • Statistical inference by confidence intervals: Issues of interpretation and utilization
    • Sim J, Reid N. Statistical inference by confidence intervals: issues of interpretation and utilization, Phys Ther 1999; 79: 186-95.
    • (1999) Phys Ther , vol.79 , pp. 186-195
    • Sim, J.1    Reid, N.2
  • 59
    • 0030786072 scopus 로고    scopus 로고
    • La génétique du diabète insulinodépendant. Intérêt dans la pratique biologique.
    • Danze PM, Penet S, Fajardy I. La génétique du diabète insulinodépendant. Intérêt dans la pratique biologique. Ann Biol 1997; 55: 537-44.
    • (1997) Ann Biol , vol.55 , pp. 537-544
    • Danze, P.M.1    Penet, S.2    Fajardy, I.3
  • 60
    • 0028674109 scopus 로고
    • The genes influencing the susceptibility to IDDM in humans
    • Faas S, Trucco M. The genes influencing the susceptibility to IDDM in humans. J Endocrinol Invest 1994; 17: 477-95.
    • (1994) J Endocrinol Invest , vol.17 , pp. 477-495
    • Faas, S.1    Trucco, M.2
  • 61
    • 0025949228 scopus 로고
    • The contribution of non-MIIC genes to susceptibility to autoimmune diseases
    • Garchon HJ, Bach JF. The contribution of non-MIIC genes to susceptibility to autoimmune diseases. Hum Immunol 1991; 32: 1-30.
    • (1991) Hum Immunol , vol.32 , pp. 1-30
    • Garchon, H.J.1    Bach, J.F.2
  • 62
    • 0242524453 scopus 로고    scopus 로고
    • The inherited basis of diabetes mellitus: Implications for the genetic analysis of complex traits
    • Florez JC, Hirschhorn J, Altshuler D. The inherited basis of diabetes mellitus: implications for the genetic analysis of complex traits. Annu Rev Genomics Hum Genet 2003; 4: 257-91.
    • (2003) Annu Rev Genomics Hum Genet , vol.4 , pp. 257-291
    • Florez, J.C.1    Hirschhorn, J.2    Altshuler, D.3
  • 63
    • 0034744361 scopus 로고    scopus 로고
    • How selection shapes variation of the human major histocompatibility complex: A review
    • Meyer D, Thomson G. How selection shapes variation of the human major histocompatibility complex: a review. Ann Intern Med 2001; 65: 1-26.
    • (2001) Ann Intern Med , vol.65 , pp. 1-26
    • Meyer, D.1    Thomson, G.2
  • 64
    • 0030726549 scopus 로고    scopus 로고
    • From pathomecanisms to prediction, prevention and improved care of insulin-dependent diabetes mellitus in children
    • Akerblom HK, Knip M, Simell O. From pathomecanisms to prediction, prevention and improved care of insulin-dependent diabetes mellitus in children. Ann Med 1997; 29: 383-5.
    • (1997) Ann Med , vol.29 , pp. 383-385
    • Akerblom, H.K.1    Knip, M.2    Simell, O.3
  • 66
    • 0035928391 scopus 로고    scopus 로고
    • Type 1A diabetes: New perspectives on disease pathogenesis and treatment
    • Atkinson MA, Eisenbarth GS. Type 1A diabetes: new perspectives on disease pathogenesis and treatment. Lancet 2001; 358: 221-9.
    • (2001) Lancet , vol.358 , pp. 221-229
    • Atkinson, M.A.1    Eisenbarth, G.S.2
  • 67
    • 0036709940 scopus 로고    scopus 로고
    • Current knowledge of Japanese type 1 diabetic syndrome
    • Abiru N, Kawasaki E, Eguch K. Current knowledge of Japanese type 1 diabetic syndrome. Diabetes Metab Res Rev 2002; 18: 357-66.
    • (2002) Diabetes Metab Res Rev , vol.18 , pp. 357-366
    • Abiru, N.1    Kawasaki, E.2    Eguch, K.3
  • 68
    • 0028009661 scopus 로고
    • Lawrence Lecture; The emperor's new genes: 1993 RD Lawrence lecture
    • Todd JA. Lawrence Lecture; The emperor's new genes: 1993 RD Lawrence lecture. Diabet Med 1994: 11: 6-16.
    • (1994) Diabet Med , vol.11 , pp. 6-16
    • Todd, J.A.1
  • 69
    • 0027238178 scopus 로고
    • Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to type 1 (insulin-dependent) diabetes mellitus
    • Thorsby E, Ronningen K. Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to type 1 (insulin-dependent) diabetes mellitus. Diabetologia 1993; 36: 371-7.
    • (1993) Diabetologia , vol.36 , pp. 371-377
    • Thorsby, E.1    Ronningen, K.2
  • 70
    • 0023135007 scopus 로고
    • Assessing the role of HLA-linked and unlinked determinants of disease
    • Risch N. Assessing the role of HLA-linked and unlinked determinants of disease. Am J Hum Genet 1987; 40: 1-14.
    • (1987) Am J Hum Genet , vol.40 , pp. 1-14
    • Risch, N.1
  • 71
    • 0021709495 scopus 로고
    • Measuring the genetic contribution of a single locus to a multilocus disease
    • Rotter J, Landaw E. Measuring the genetic contribution of a single locus to a multilocus disease. Clin Genet 1984; 26: 529-42.
    • (1984) Clin Genet , vol.26 , pp. 529-542
    • Rotter, J.1    Landaw, E.2
  • 72
    • 25444462961 scopus 로고    scopus 로고
    • Association of HLA-class II alleles and susceptibility to type 1 diabetes in southern Iranian patients
    • Amirzargar A, Mostafavi H, Farjadian SH, Ghaderi A. Association of HLA-class II alleles and susceptibility to type 1 diabetes in southern Iranian patients. Int J Med Sci 2000; 25: 109-13.
    • (2000) Int J Med Sci , vol.25 , pp. 109-113
    • Amirzargar, A.1    Mostafavi, H.2    Farjadian, S.H.3    Ghaderi, A.4
  • 73
    • 0033984784 scopus 로고    scopus 로고
    • Sanjeevi CB. HLA-DQ6-mediated protection in IDDM. Hum Immunol 2000; 61: 148-53.
    • Sanjeevi CB. HLA-DQ6-mediated protection in IDDM. Hum Immunol 2000; 61: 148-53.
  • 74
    • 0033358374 scopus 로고    scopus 로고
    • The predisposition to type I diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene
    • Lie BA, Todd JA, Pociot F, et al. The predisposition to type I diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene. Am J Hum Genet 1999; 64: 793-800.
    • (1999) Am J Hum Genet , vol.64 , pp. 793-800
    • Lie, B.A.1    Todd, J.A.2    Pociot, F.3
  • 75
    • 0030701914 scopus 로고    scopus 로고
    • The effect of HLA-B allele on the IDDM risk defined by DRB1*04 subtypes and DQB1*0302
    • Nejentsev S, Reijonen H, Adojaan B, et al. The effect of HLA-B allele on the IDDM risk defined by DRB1*04 subtypes and DQB1*0302, Diabetes 1997; 46: 1888-92.
    • (1997) Diabetes , vol.46 , pp. 1888-1892
    • Nejentsev, S.1    Reijonen, H.2    Adojaan, B.3
  • 76
    • 0030635589 scopus 로고    scopus 로고
    • Diabetes in the 1990s-an overview
    • Jan-Mar, 2-8
    • Jiwa F. Diabetes in the 1990s-an overview. Statistical Bulletin 1997, Jan-Mar, 2-8.
    • (1997) Statistical Bulletin
    • Jiwa, F.1
  • 77
    • 0028882717 scopus 로고
    • Population analysis of protection by HLA-DR and DQ genes from insulin-dependent diabetes mellitus in Swedish children with insulin-dependent diabetes and controls
    • Kockum I, Sarjeevi CB, Eastman S, Landin-Olsson M, Dahlquist G, Lemmark A. Population analysis of protection by HLA-DR and DQ genes from insulin-dependent diabetes mellitus in Swedish children with insulin-dependent diabetes and controls. Eur J Immunogenet 1995; 22: 443-65.
    • (1995) Eur J Immunogenet , vol.22 , pp. 443-465
    • Kockum, I.1    Sarjeevi, C.B.2    Eastman, S.3    Landin-Olsson, M.4    Dahlquist, G.5    Lemmark, A.6
  • 78
    • 25444521313 scopus 로고    scopus 로고
    • Aribi M, Moulessehoul S, Benabadji AB, Kendoucitani M. HLA DR phenotypic frequencies and genetic risk or Type I diabetes in west region ofAlgeria, Tlemcen. BMC Genet 2004; 5: 24.
    • Aribi M, Moulessehoul S, Benabadji AB, Kendoucitani M. HLA DR phenotypic frequencies and genetic risk or Type I diabetes in west region ofAlgeria, Tlemcen. BMC Genet 2004; 5: 24.
  • 79
    • 0026615158 scopus 로고
    • The HLA-DRBI*0405 haplotype is most strongly associated with IDDM in Algerians
    • Djoulah S, Khalil I, Beressi JP, et al. The HLA-DRBI*0405 haplotype is most strongly associated with IDDM in Algerians. Eur J Immunogenet 1992; 19: 381-9.
    • (1992) Eur J Immunogenet , vol.19 , pp. 381-389
    • Djoulah, S.1    Khalil, I.2    Beressi, J.P.3
  • 80
    • 16244420705 scopus 로고    scopus 로고
    • Hypothesis for the pathogenesis of type IA diabetes
    • Jasinski JM, Eisenbarth GS. Hypothesis for the pathogenesis of type IA diabetes. Drugs Today (Barc) 2005; 41: 141-9.
    • (2005) Drugs Today (Barc) , vol.41 , pp. 141-149
    • Jasinski, J.M.1    Eisenbarth, G.S.2
  • 81
    • 0024421277 scopus 로고
    • Immunological disorders of type I diabetes mellitus
    • Ziegler M, Ziegler B. Immunological disorders of type I diabetes mellitus. Exp Clin Endocrmol 1989; 94: 97-114.
    • (1989) Exp Clin Endocrmol , vol.94 , pp. 97-114
    • Ziegler, M.1    Ziegler, B.2
  • 83
    • 0033028541 scopus 로고    scopus 로고
    • MHC class II-dependent activation of CD4+ T cell hybridomas by human mast cells through superantigen presentation
    • Poncet P, Arock M, David B. MHC class II-dependent activation of CD4+ T cell hybridomas by human mast cells through superantigen presentation. J Leukoc Biol 1999; 66: 105-12.
    • (1999) J Leukoc Biol , vol.66 , pp. 105-112
    • Poncet, P.1    Arock, M.2    David, B.3
  • 84
    • 0027374971 scopus 로고
    • Antigen-dependent stimulation by bone marrow-derived mast cells of MHC class II-restricted T cell hybridoma
    • Frandji P, Oskeritzian C, Cacaraci F, et al. Antigen-dependent stimulation by bone marrow-derived mast cells of MHC class II-restricted T cell hybridoma. J Immunol 1993; 151: 6318-28.
    • (1993) J Immunol , vol.151 , pp. 6318-6328
    • Frandji, P.1    Oskeritzian, C.2    Cacaraci, F.3
  • 85
    • 0028239150 scopus 로고
    • Two subsets of HLA-DQ-A1 alleles mark phenotypic variation in levels of insulin autoantibodies in first degree relatives at risk for insulin-dependent mellitus
    • Pugliese A, Bugawan T, Moromisato R, et al. Two subsets of HLA-DQ-A1 alleles mark phenotypic variation in levels of insulin autoantibodies in first degree relatives at risk for insulin-dependent mellitus. J Clin Invest 1994; 93: 2447-52.
    • (1994) J Clin Invest , vol.93 , pp. 2447-2452
    • Pugliese, A.1    Bugawan, T.2    Moromisato, R.3
  • 86
    • 0028907414 scopus 로고
    • A new marker in the HLA class I region is associated with the age at onset of IDDM
    • Demaine AG, Hibberd ML, Mangles D, Millward BA. A new marker in the HLA class I region is associated with the age at onset of IDDM. Diabetologia 1995; 38: 623-8.
    • (1995) Diabetologia , vol.38 , pp. 623-628
    • Demaine, A.G.1    Hibberd, M.L.2    Mangles, D.3    Millward, B.A.4
  • 87
    • 3643085912 scopus 로고    scopus 로고
    • Etiopathogénie du diabèe de type I.
    • Timist J. Etiopathogénie du diabèe de type I. Rev Prat 1996; 46: 560-4.
    • (1996) Rev Prat , vol.46 , pp. 560-564
    • Timist, J.1
  • 89
    • 0026547758 scopus 로고
    • Dose effect.of cis and trans encoded HLA-DQalphabeta heterodimers in IDDM susceptibility
    • Khalil I, Deschamps I, Lepage V, Aladaccak R, Degos L, Hors J. Dose effect.of cis and trans encoded HLA-DQalphabeta heterodimers in IDDM susceptibility. Diabetes 1992; 41: 378-84.
    • (1992) Diabetes , vol.41 , pp. 378-384
    • Khalil, I.1    Deschamps, I.2    Lepage, V.3    Aladaccak, R.4    Degos, L.5    Hors, J.6
  • 90
    • 0026035145 scopus 로고
    • Le dégéquilibre de liaison.
    • Feingold J. Le dégéquilibre de liaison. Med Sci (Paris) 1991; 7: 161-8.
    • (1991) Med Sci (Paris) , vol.7 , pp. 161-168
    • Feingold, J.1
  • 92
    • 27644566135 scopus 로고    scopus 로고
    • Glutamic acid decarboxylase autoantibody prevalence and association with HLA genotype in patients with younger-onset type 1 diabetes and proliferative diabetic retinopathy
    • Mimura T, Funatsu H, Uchigata Y, et al. Glutamic acid decarboxylase autoantibody prevalence and association with HLA genotype in patients with younger-onset type 1 diabetes and proliferative diabetic retinopathy. Ophthalmology 2005; 112: 1904-9.
    • (2005) Ophthalmology , vol.112 , pp. 1904-1909
    • Mimura, T.1    Funatsu, H.2    Uchigata, Y.3
  • 93
    • 0038281106 scopus 로고    scopus 로고
    • Relationship between human leukocyte antigen status and proliferative diabetic retinopathy in patients with younger-onset type 1 diabetes mellitus
    • Mimura T, Funatsu H, Uchigata YK, et al. Relationship between human leukocyte antigen status and proliferative diabetic retinopathy in patients with younger-onset type 1 diabetes mellitus. Am J Ophthalmol 2003; 135: 844-8.
    • (2003) Am J Ophthalmol , vol.135 , pp. 844-848
    • Mimura, T.1    Funatsu, H.2    Uchigata, Y.K.3
  • 94
    • 0028990939 scopus 로고
    • HLA-DRB1 *0401 is associated with susceptibility to insulin-dependent diabetes mellitus independently of the DQB1 locus
    • Tait BD, Drummond BP, Varney MD, Harrison LC. HLA-DRB1 *0401 is associated with susceptibility to insulin-dependent diabetes mellitus independently of the DQB1 locus. Eur J Immunogenet 1995; 22: 289-97.
    • (1995) Eur J Immunogenet , vol.22 , pp. 289-297
    • Tait, B.D.1    Drummond, B.P.2    Varney, M.D.3    Harrison, L.C.4
  • 95
    • 0031308972 scopus 로고    scopus 로고
    • the WHO DiaMon Molecular Epidemiologie Sub-Project Group. Molecular Epidemiology of Insulin-dependent Diabetes Mellitus: WHO Diamon Project
    • Dorman J, the WHO DiaMon Molecular Epidemiologie Sub-Project Group. Molecular Epidemiology of Insulin-dependent Diabetes Mellitus: WHO Diamon Project. Gac Med Mex 1997; 133 (Suppl 1): 151-4.
    • (1997) Gac Med Mex , vol.133 , Issue.SUPPL. 1 , pp. 151-154
    • Dorman, J.1
  • 97
    • 0024295286 scopus 로고
    • HLA antigens and insulin-dependent diabetes
    • Todd JA, Bell JI, McDevitt HO. HLA antigens and insulin-dependent diabetes. Nature 1988; 333: 710.
    • (1988) Nature , vol.333 , pp. 710
    • Todd, J.A.1    Bell, J.I.2    McDevitt, H.O.3
  • 98
    • 0025326199 scopus 로고
    • A combination of HLA-DQ beta Asp57-negative and HLA DQalpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus
    • Kalil I, d'Auriol L, Gobet M, et al. A combination of HLA-DQ beta Asp57-negative and HLA DQalpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus. J Clin Invest 1990; 85: 1315-9.
    • (1990) J Clin Invest , vol.85 , pp. 1315-1319
    • Kalil, I.1    d'Auriol, L.2    Gobet, M.3
  • 99
    • 0033014666 scopus 로고    scopus 로고
    • Nakamura Knimunogenetics of insulin-dependent diabetes mellitus
    • Kla KKino Y, Ito T, Hirai H, Nakamura Knimunogenetics of insulin-dependent diabetes mellitus. Acta Paediatr 1999; Suppl 427: 3-7.
    • (1999) Acta Paediatr , Issue.SUPPL. 427 , pp. 3-7
    • Kla KKino, Y.1    Ito, T.2    Hirai, H.3
  • 100
    • 0027933734 scopus 로고
    • A genome-wide search for human type I diabetes susceptibility genes
    • Davies JL, Kwaguchi Y, Bennett ST, et al. A genome-wide search for human type I diabetes susceptibility genes. Nature 1994; 371: 130-6.
    • (1994) Nature , vol.371 , pp. 130-136
    • Davies, J.L.1    Kwaguchi, Y.2    Bennett, S.T.3
  • 101
    • 33644693805 scopus 로고    scopus 로고
    • Genetic heterogeneity in association of the SUM04 M55 Variant with susceptibility to type 1 diabetes
    • Noso S, Ikegami H, Fujisawa T, et al. Genetic heterogeneity in association of the SUM04 M55 Variant with susceptibility to type 1 diabetes. Diabetes 2005; 54: 3582-6.
    • (2005) Diabetes , vol.54 , pp. 3582-3586
    • Noso, S.1    Ikegami, H.2    Fujisawa, T.3
  • 102
    • 18444366769 scopus 로고    scopus 로고
    • Functional variants in SUMO4, TAB2, and NFkappaB and the risk of type I diabetes
    • Ksoy R, Concannon P. Functional variants in SUMO4, TAB2, and NFkappaB and the risk of type I diabetes. Genes Immun 2005, 6: 231-5.
    • (2005) Genes Immun , vol.6 , pp. 231-235
    • Ksoy, R.1    Concannon, P.2
  • 103
    • 3042644131 scopus 로고    scopus 로고
    • A M55 polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus
    • Bohren M, Nadkarni VSong JH, Gabbay K, Owerbach D. A M55 polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus. J Biol Chem 2004; 279: 27233-8.
    • (2004) J Biol Chem , vol.279 , pp. 27233-27238
    • Bohren, M.1    Nadkarni VSong, J.H.2    Gabbay, K.3    Owerbach, D.4
  • 104
    • 3543046736 scopus 로고    scopus 로고
    • Guo D, Li M, Kang Y, et al. Functional variant of SUMO4, a new I kappa B alpha modifici, is associated with type I diabetes. Nat Genet 2004; 36: 837-41. published erratum appears In Nat Genet 2004; 36: 1024].
    • Guo D, Li M, Kang Y, et al. Functional variant of SUMO4, a new I kappa B alpha modifici, is associated with type I diabetes. Nat Genet 2004; 36: 837-41. published erratum appears In Nat Genet 2004; 36: 1024].
  • 105
    • 0036297540 scopus 로고    scopus 로고
    • Burkart VHeat shock protein 60 elicits abnormal response in macrophages of diabetes-prone non-obese diabetic mice
    • Adler T, Akiyama H, Herder C, Klb H, Burkart VHeat shock protein 60 elicits abnormal response in macrophages of diabetes-prone non-obese diabetic mice. Biochem Biophys Res Common 2002; 294: 592-6.
    • (2002) Biochem Biophys Res Common , vol.294 , pp. 592-596
    • Adler, T.1    Akiyama, H.2    Herder, C.3    Klb, H.4
  • 106
    • 0036498093 scopus 로고    scopus 로고
    • Antibodies against different epitopes of heat-shock protein 60 in children with type I diabetes mellitus
    • Horvath L, Cervenak L, Oroszlan M, et al. Antibodies against different epitopes of heat-shock protein 60 in children with type I diabetes mellitus. Immunol Lett 2002; 80: 155-62.
    • (2002) Immunol Lett , vol.80 , pp. 155-162
    • Horvath, L.1    Cervenak, L.2    Oroszlan, M.3
  • 107
    • 0030004757 scopus 로고    scopus 로고
    • NOD Mouse diabetes: The ubiq uitous mouse hsp60 is a beta-cell target antigen of autoimmune T cells
    • Birk OS, Elias D, Weiss AS, et al. NOD Mouse diabetes: the ubiq uitous mouse hsp60 is a beta-cell target antigen of autoimmune T cells. J Autoimmun 1996; 9: 159-66.
    • (1996) J Autoimmun , vol.9 , pp. 159-166
    • Birk, O.S.1    Elias, D.2    Weiss, A.S.3
  • 108
    • 0027479118 scopus 로고
    • Sequence homologies between hsp60 and autoantigens
    • Jones DB, Coulson AF, Duff GW. Sequence homologies between hsp60 and autoantigens. Immunol Today 1993; 14: 115-8.
    • (1993) Immunol Today , vol.14 , pp. 115-118
    • Jones, D.B.1    Coulson, A.F.2    Duff, G.W.3
  • 111
    • 3242758107 scopus 로고    scopus 로고
    • Molecular basis of predisposition to develop type 1 diabetes mellitus in North Indians
    • Rani R, Sood A, Goswami R. Molecular basis of predisposition to develop type 1 diabetes mellitus in North Indians. Tissue Antigens 2004; 64: 145-55.
    • (2004) Tissue Antigens , vol.64 , pp. 145-155
    • Rani, R.1    Sood, A.2    Goswami, R.3
  • 112
    • 27944457740 scopus 로고    scopus 로고
    • Strong association of insulin gene INS-MTR polymorphisms with type I diabetes in the Romanian population, Rom
    • Guja C, Guja L, Nutland S, Rance H, Todd JA, Ionescu-Tirgoviste C. Strong association of insulin gene INS-MTR polymorphisms with type I diabetes in the Romanian population, Rom J Interm Med 2004; 42: 313-23.
    • (2004) J Interm Med , vol.42 , pp. 313-323
    • Guja, C.1    Guja, L.2    Nutland, S.3    Rance, H.4    Todd, J.A.5    Ionescu-Tirgoviste, C.6
  • 113
    • 0030770285 scopus 로고    scopus 로고
    • Associations of GAD-65 and IA-2-autoantibodies with genetic risk markers in new-onset IDDM patients and their siblings
    • Vandewalle CL, Falorni A, Lernmark Å et al. Associations of GAD-65 and IA-2-autoantibodies with genetic risk markers in new-onset IDDM patients and their siblings. Diabetes Care 1997; 10: 1547-52.
    • (1997) Diabetes Care , vol.10 , pp. 1547-1552
    • Vandewalle, C.L.1    Falorni, A.2    Lernmark, A.3
  • 114
  • 115
    • 0032744971 scopus 로고    scopus 로고
    • Associations of IGF2 Apal RFLP and INS MTR class I allele size with obesity
    • ODell SD, Bujac SR, Miller GJ, Day IN. Associations of IGF2 Apal RFLP and INS MTR class I allele size with obesity. Eur. J Hum Genet 1999; 7: 821-7.
    • (1999) Eur. J Hum Genet , vol.7 , pp. 821-827
    • ODell, S.D.1    Bujac, S.R.2    Miller, G.J.3    Day, I.N.4
  • 116
    • 10744222979 scopus 로고    scopus 로고
    • IDDM2insulin MTR modifies risk conferred by IDDMIHLA for development of Type I diabetes and associated autoimmunity
    • Walter M, Albert E, Conrad M, et al. IDDM2insulin MTR modifies risk conferred by IDDMIHLA for development of Type I diabetes and associated autoimmunity. Diabetologia 2003; 46: 712-20.
    • (2003) Diabetologia , vol.46 , pp. 712-720
    • Walter, M.1    Albert, E.2    Conrad, M.3
  • 117
    • 0035217582 scopus 로고    scopus 로고
    • Ibanez. L, Ong KPotau N, Marcos MVde Zgher F, Dunger D. Insulin gene variable number of tandem repeat genotype and the low birth weight, precocious pubarche, and hyperinsulinism seqence. J Clin Endocrinol Metab 2001; 86: 5788-93.
    • Ibanez. L, Ong KPotau N, Marcos MVde Zgher F, Dunger D. Insulin gene variable number of tandem repeat genotype and the low birth weight, precocious pubarche, and hyperinsulinism seqence. J Clin Endocrinol Metab 2001; 86: 5788-93.
  • 118
    • 0031018819 scopus 로고    scopus 로고
    • Insulin expression in human thymus is modulated by INS MTR alleles at the IDDM2 locus
    • Miadis P, Bennett ST, Todd JA, et al. Insulin expression in human thymus is modulated by INS MTR alleles at the IDDM2 locus. Nat genet 1997; 15: 289-92.
    • (1997) Nat genet , vol.15 , pp. 289-292
    • Miadis, P.1    Bennett, S.T.2    Todd, J.A.3
  • 119
    • 0034891347 scopus 로고    scopus 로고
    • Class III alleles of the variable number of tandem repeat insulin polymorphism associated with silencing of thymic insulin predispose to type I diabetes
    • Miadis P, Ounissi-Benkalha H, Palumbo M, et al. Class III alleles of the variable number of tandem repeat insulin polymorphism associated with silencing of thymic insulin predispose to type I diabetes. J Clin Endocrinol Metab 2001; 86: 3705-10.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3705-3710
    • Miadis, P.1    Ounissi-Benkalha, H.2    Palumbo, M.3
  • 120
    • 1842533557 scopus 로고    scopus 로고
    • Haplotypic analyses of the IGF2-INS-TH gene cluster in relation to cardiovascular risk traits
    • Rodriguez S, Gaunt TR, ODell SD, et al. Haplotypic analyses of the IGF2-INS-TH gene cluster in relation to cardiovascular risk traits. Hum Mol Genet 2004; 13: 715-25.
    • (2004) Hum Mol Genet , vol.13 , pp. 715-725
    • Rodriguez, S.1    Gaunt, T.R.2    ODell, S.D.3
  • 121
    • 0035345428 scopus 로고    scopus 로고
    • Concordance for type 1 diabetes in identical twins is affected by insulin genotype
    • Metcalfe K, Hitman GA, Rowe RE, et al. Concordance for type 1 diabetes in identical twins is affected by insulin genotype. Diabetes Care 2001; 838-42.
    • (2001) Diabetes Care , pp. 838-842
    • Metcalfe, K.1    Hitman, G.A.2    Rowe, R.E.3
  • 122
    • 0032545452 scopus 로고    scopus 로고
    • Molecular basis of T cell inactivation by CTLA-4
    • Lee M, Chuang E, Griffin M, et al. Molecular basis of T cell inactivation by CTLA-4. Science 1998; 282: 2263-6.
    • (1998) Science , vol.282 , pp. 2263-2266
    • Lee, M.1    Chuang, E.2    Griffin, M.3
  • 123
    • 33646052603 scopus 로고    scopus 로고
    • Clinical review: Type 1 diabetes-associated autoimmunity: natural history, genetic associations, and screening
    • Barker JM. Clinical review: Type 1 diabetes-associated autoimmunity: natural history, genetic associations, and screening. J Clin Endocrinol Metab 2006; 91: 1210-7.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1210-1217
    • Barker, J.M.1
  • 124
    • 20044386299 scopus 로고    scopus 로고
    • Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties
    • Larsen CP, Pearson TC, Adams AB, et al. Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties. Am J Transplant 2005; 5: 443-53.
    • (2005) Am J Transplant , vol.5 , pp. 443-453
    • Larsen, C.P.1    Pearson, T.C.2    Adams, A.B.3
  • 125
    • 0037330704 scopus 로고    scopus 로고
    • CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties
    • Vsu C, Wang A, Gorla SR, Kithamana S, Prabhakar BS, Holterman MJ. CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties. Int Immunol 2003; 15: 167-75.
    • (2003) Int Immunol , vol.15 , pp. 167-175
    • Vsu, C.1    Wang, A.2    Gorla, S.R.3    Kithamana, S.4    Prabhakar, B.S.5    Holterman, M.J.6
  • 126
    • 2942738825 scopus 로고    scopus 로고
    • The emerging role of the CTLA-4 gene in autoimmune endocrinopathies
    • Mdya B, Pearce S. The emerging role of the CTLA-4 gene in autoimmune endocrinopathies. Eur J Endocrinol 2004; 150: 619-26.
    • (2004) Eur J Endocrinol , vol.150 , pp. 619-626
    • Mdya, B.1    Pearce, S.2
  • 128
    • 27844447147 scopus 로고    scopus 로고
    • Immunogenetics of type 1 diabetes
    • Kn MS, Polychronakos C. Immunogenetics of type 1 diabetes. Horm Res 2005; 64: 180-8.
    • (2005) Horm Res , vol.64 , pp. 180-188
    • Kn, M.S.1    Polychronakos, C.2
  • 129
    • 23644443079 scopus 로고    scopus 로고
    • Association of non-HLA genes with type 1 diabetes autoimmunity
    • Steck AK Bugawan TL, Mdes AM, et al. Association of non-HLA genes with type 1 diabetes autoimmunity. Diabetes 2005; 54: 2482-6.
    • (2005) Diabetes , vol.54 , pp. 2482-2486
    • Steck, A.K.1    Bugawan, T.L.2    Mdes, A.M.3
  • 130
    • 21244490890 scopus 로고    scopus 로고
    • CTLA-4 gene polymorphisms and susceptibility to type 1 diabetes mellitus: A HuGE Review and meta-analysis
    • Kvvoura FK Ioannidis JP. CTLA-4 gene polymorphisms and susceptibility to type 1 diabetes mellitus: a HuGE Review and meta-analysis. Am J Epidemiol 2005; 162: 3-16.
    • (2005) Am J Epidemiol , vol.162 , pp. 3-16
    • Kvvoura, F.K.1    Ioannidis, J.P.2
  • 131
    • 18044397323 scopus 로고    scopus 로고
    • CTLA-4 49 AG polymorphism is associated with predisposition to type 1 diabetes in Iranians
    • Mojtahedi ZOmrani GR, Doroudchi M, Ghaderi A. CTLA-4 49 AG polymorphism is associated with predisposition to type 1 diabetes in Iranians. Diabetes Res Clin Pract 2005; 68: 111-6.
    • (2005) Diabetes Res Clin Pract , vol.68 , pp. 111-116
    • Mojtahedi ZOmrani, G.R.1    Doroudchi, M.2    Ghaderi, A.3
  • 132
    • 4444354041 scopus 로고    scopus 로고
    • Evidence for CTLA4 as a susceptibility gene for systemic lupus erythematosus
    • Barreto M, Santos E, Ferreira R, et al. Evidence for CTLA4 as a susceptibility gene for systemic lupus erythematosus. Eur J Hum Genet 2004; 12: 620-6.
    • (2004) Eur J Hum Genet , vol.12 , pp. 620-626
    • Barreto, M.1    Santos, E.2    Ferreira, R.3
  • 133
    • 10344228267 scopus 로고    scopus 로고
    • CTLA-4 (CD 152) gene polymorphism at position 49 in exon 1 in Graves' disease in a Polish population of the Lower Silesian region
    • Frydecka I, Daroszewski J, Suwalska K et al. CTLA-4 (CD 152) gene polymorphism at position 49 in exon 1 in Graves' disease in a Polish population of the Lower Silesian region. Arch Immunol Titer Exp (Warsz) 2004; 52: 369-74.
    • (2004) Arch Immunol Titer Exp (Warsz) , vol.52 , pp. 369-374
    • Frydecka, I.1    Daroszewski, J.2    Suwalska, K.3
  • 134
    • 18044390659 scopus 로고    scopus 로고
    • Immunogenetics of Hashimotos thyroiditis
    • Chistiakov DA. Immunogenetics of Hashimotos thyroiditis. J Autoimmune Dis 2004; 2: 1.
    • (2004) J Autoimmune Dis , vol.2 , pp. 1
    • Chistiakov, D.A.1
  • 135
    • 0042353836 scopus 로고    scopus 로고
    • CTLA-4 and its role in autoimmune thyroid disease
    • Chistiakov DA, Turakulov RI. CTLA-4 and its role in autoimmune thyroid disease. J Mol Endocrinol 2003; 31: 21-36.
    • (2003) J Mol Endocrinol , vol.31 , pp. 21-36
    • Chistiakov, D.A.1    Turakulov, R.I.2
  • 136
    • 0034139830 scopus 로고    scopus 로고
    • CTLA-4 in autoimmune diseases-a general susceptibility gene to autoimmunity?
    • Kstiansen OP, Larsen M, Pociot F. CTLA-4 in autoimmune diseases-a general susceptibility gene to autoimmunity? Genes Immun 2000; 1: 170-84.
    • (2000) Genes Immun , vol.1 , pp. 170-184
    • Kstiansen, O.P.1    Larsen, M.2    Pociot, F.3
  • 137
    • 1242292946 scopus 로고    scopus 로고
    • Mechanisms of genetic susceptibility to type 1 diabetes: Beyond HLA
    • Anjos S, Polychronakos C. Mechanisms of genetic susceptibility to type 1 diabetes: beyond HLA. Mol Genet Metab 2004; 81: 187-95.
    • (2004) Mol Genet Metab , vol.81 , pp. 187-195
    • Anjos, S.1    Polychronakos, C.2
  • 138
    • 18744400860 scopus 로고    scopus 로고
    • Chistiakov DA, Savostanov KNosikov. VCTLA4 gene polymorphisms are associated with, and linked to, insulin-dependent diabetes mellitus in a Russian population. BMC Genet 2001; 2: 6.
    • Chistiakov DA, Savostanov KNosikov. VCTLA4 gene polymorphisms are associated with, and linked to, insulin-dependent diabetes mellitus in a Russian population. BMC Genet 2001; 2: 6.
  • 139
    • 28444435565 scopus 로고    scopus 로고
    • Lack of correlation between the levels of soluble cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and the CT-60 genotypes
    • Purohit S, Podolsky R, Collins C, et al. Lack of correlation between the levels of soluble cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and the CT-60 genotypes. J Autoimmune Dis 2005; 2: 28.
    • (2005) J Autoimmune Dis , vol.2 , pp. 28
    • Purohit, S.1    Podolsky, R.2    Collins, C.3
  • 140
    • 0037648405 scopus 로고    scopus 로고
    • Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
    • Ueda H, Howson JM, Esposito L, et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 2003; 423: 506-11.
    • (2003) Nature , vol.423 , pp. 506-511
    • Ueda, H.1    Howson, J.M.2    Esposito, L.3
  • 141
    • 0032728162 scopus 로고    scopus 로고
    • A soluble form of CTLA-4 generated by alternative splicing is expressed by non-stimulated human T cells
    • Magistrelli G, Jcannin P, Herbault N, et al. A soluble form of CTLA-4 generated by alternative splicing is expressed by non-stimulated human T cells. Eur J Immunol 1999; 29: 3596-602.
    • (1999) Eur J Immunol , vol.29 , pp. 3596-3602
    • Magistrelli, G.1    Jcannin, P.2    Herbault, N.3
  • 142
    • 0142259734 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor: A regulator of innate immunity
    • Calandra T, Roger T. Macrophage migration inhibitory factor: a regulator of innate immunity. Nat Rev Immunol 2003; 3: 791-800.
    • (2003) Nat Rev Immunol , vol.3 , pp. 791-800
    • Calandra, T.1    Roger, T.2
  • 143
    • 0034922171 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor and innate immune responses to bacterial infections
    • Froidevaux C, Roger T, Martin C, Glauser MP, Calandra T. Macrophage migration inhibitory factor and innate immune responses to bacterial infections. Crit Care Med 2001; 29 (Suppl 1): S13-5.
    • (2001) Crit Care Med , vol.29 , Issue.SUPPL. 1
    • Froidevaux, C.1    Roger, T.2    Martin, C.3    Glauser, M.P.4    Calandra, T.5
  • 144
    • 12344309160 scopus 로고    scopus 로고
    • Role of macrophage migration inhibitory factor (MIF) in the skin
    • Shimizu T. Role of macrophage migration inhibitory factor (MIF) in the skin. J Dermatol Sci 2005; 37: 65-73.
    • (2005) J Dermatol Sci , vol.37 , pp. 65-73
    • Shimizu, T.1
  • 145
    • 1842791473 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor is induced by thrombin and factor Xa in endothelial cells
    • Shimizu T, Nishihira J, Watanabe H, et al. Macrophage migration inhibitory factor is induced by thrombin and factor Xa in endothelial cells. J Biol Chem 2004; 279: 13729-37.
    • (2004) J Biol Chem , vol.279 , pp. 13729-13737
    • Shimizu, T.1    Nishihira, J.2    Watanabe, H.3
  • 146
    • 0141446025 scopus 로고    scopus 로고
    • The A 16-residue peptide fragment of macrophage migration inhibitory factor, MIF-(50-65), exhibits redox activity and has MIF-like biological functions
    • Nguyen MT, Beck J, Lue H, et al. The A 16-residue peptide fragment of macrophage migration inhibitory factor, MIF-(50-65), exhibits redox activity and has MIF-like biological functions. J Biol Chem 2003; 278: 33654-71.
    • (2003) J Biol Chem , vol.278 , pp. 33654-33671
    • Nguyen, M.T.1    Beck, J.2    Lue, H.3
  • 147
    • 0036281129 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor activates antigen-presenting dendritic cells and induces inflammatory cytokines in ulcerative colitis
    • Murakami H, Akbar SM, Matsui H, Horiike N, Onji M. Macrophage migration inhibitory factor activates antigen-presenting dendritic cells and induces inflammatory cytokines in ulcerative colitis. Clin Exp Immunol 2002; 128: 504-10.
    • (2002) Clin Exp Immunol , vol.128 , pp. 504-510
    • Murakami, H.1    Akbar, S.M.2    Matsui, H.3    Horiike, N.4    Onji, M.5
  • 148
    • 0041731896 scopus 로고    scopus 로고
    • Molecular interaction and enzymatic activity of macrophage migration inhibitory factor with immunorelevant peptides
    • Potolicchio I, Santambrogio L, Strominger JL. Molecular interaction and enzymatic activity of macrophage migration inhibitory factor with immunorelevant peptides. J Biol Chem 2003; 278: 30889-95.
    • (2003) J Biol Chem , vol.278 , pp. 30889-30895
    • Potolicchio, I.1    Santambrogio, L.2    Strominger, J.L.3
  • 150
    • 48749124762 scopus 로고    scopus 로고
    • MEDI 581. MIF knockout mice are resistant to the development of type 1 diabetes
    • Al-Abed Y, Cvetkovic I, Miljkovic D, Metz C, Nicoletti F, Stosic-Grujicic S, editors, March 13-17; San Diego, CA, USA
    • Al-Abed Y, Cvetkovic I, Miljkovic D, Metz C, Nicoletti F, Stosic-Grujicic S, editors. MEDI 581. MIF knockout mice are resistant to the development of type 1 diabetes. 229th American Chemical Society National Meeting & Exposition; 2005 March 13-17; San Diego, CA, USA.
    • (2005) 229th American Chemical Society National Meeting & Exposition
  • 151
    • 22144450700 scopus 로고    scopus 로고
    • Critical role of macrophage migration inhibitory factor activity in experimental autoimmune diabetes
    • Cvetkovic I, Al-Abed Y, Miljkovic D, et al. Critical role of macrophage migration inhibitory factor activity in experimental autoimmune diabetes. Endocrinology 2005; 146: 2942-51.
    • (2005) Endocrinology , vol.146 , pp. 2942-2951
    • Cvetkovic, I.1    Al-Abed, Y.2    Miljkovic, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.