Genetic determination of islet cell autoimmunity in monozygotic twin, dizygotic twin, and non-twin siblings of patients with type 1 diabetes: Prospective twin study

British Medical Journal

Volumn 318, Issue 7185, 1999, Pages 698-702

  Redonclo, Maria J ^a   Rewers, Marian ^a   Yu, Liping ^a   Garg, Satish ^a,b   Pilcher, Colleen C ^a   Elliott, Robert B ^b   Eisenbarth, George S ^a,b  

^a UNIVERSITY OF COLORADO DENVER   (United States)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; HLA DQ ANTIGEN;

ADOLESCENT; ADULT; ARTICLE; AUTOIMMUNITY; CHILD; CONTROLLED STUDY; DIZYGOTIC TWINS; FEMALE; GENOTYPE; HEREDITY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; MONOZYGOTIC TWINS; PANCREAS ISLET CELL; PRIORITY JOURNAL; RISK; SIBLING;

ADOLESCENT; ADULT; AGED; ANTIBODY SPECIFICITY; AUTOANTIBODIES; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; DISEASE PROGRESSION; FEMALE; HISTOCOMPATIBILITY TESTING; HUMANS; INFANT; ISLETS OF LANGERHANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 0033550904     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Verge CF. Gianani R, Vu L, Piciropaolo M, Smith T,Jackson RA, et al. Latc progression to diabetes and evidence for chronic β cell autoimmunity in identical twins of patients with type I diabetes. Diabetes 1993; 11: 1176-9.
2. Dib S, Vardi P ConncllyJ, Eiscnbarih GS, SocldnerJS. Immune changes associated with insulin dependent diabetes may remit without causing the disease: a study in identical twins, BMJ 19SG; 292: 1670.
3. Srtkanta S, Ganda OP, Eiseiihartli GS, Soeldncr JS. hlct cell antilxxlies and β cell function in monozygouc triplets and twins initially discordant for type I diabetes mcllitus. N Awg Med 1983: 308: 322-5.
4. Srikanta S, Ganda OP.Jackson RA, Glcason RE, Kaldany A, Gorovoy MR, ct al. Type I diabetes mellitus in monozygouc twins: chronic progressive beta cell dysfunctkm. Ann Intern Med 1983; 99: 320-6.
5. Kumar D, Gcmaycl NS, Dcapcn D, Kapadia D, Vamashita PH, Lee M, et al. North-American twins with IDDM: genetic, etiological, and clinical significance of disease concordance according to age, zygosity, and die interval after diagnosis in first twin. Diabetes 1993; 42: 1351-63
6. Kyvik KO, Green A, Beck-Niclsen -H. Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twins. BMJ 1995; 311: 913-7.
7. Petcrsen JS, Kj-vik KO, Bingley PJ, Gale RAM, Green A, Drybcrg T, et al. Population based study of prevalence of Met cell autoantibodies in monozygotic and dizygotic Danish twin pairs with insulin dependent diabetes mellitus. BMJ 1997; 314: 1375-9.
8. Hawkcs CH. Twin studies in diabetes mellitus. Diabet Med 1997; 17: 317-52.
9. Rowe RE, Leslie RDG. Twin studies in insulin-dependent diabetes and other autoimmune diseases. Diabetes Metab Rtv 1993; ! 1: 121 -36.
10. Atkinson MA, Maclai en NK. Islet cell auloantigcns in insulin dependent diabetcsj Clin Imnl 1993; 92: 1G03-16.
11. Verge CF, Stetiger D, Bonifacio E, Colman I'G, Pilchcr C, Binglcy PJ, et al. Combined use of autoanlibodics (IA-2ab, Gadab, IAA, ICA' in type 1 diabetes: combinatorial islet autoantiboxly workshojx Diabetes 1998; 47: 1857-66.
12. Hawa M, Rowc R, I .an MS, Notlins AU Pozzilli P, Christie MR, et al. Value of amilxxlies to islet protein tyrosine phosphata.se-like molecule in predicting type 1 diabetes. Diabè tes 1997; 16: 1270-5.
13. Rovers M, Bugawan Tl, Non is JM, Blair A, Bcaty B, Hoffman M, cl al. Newborn screening for HI markers associated with IDDM: diabetes autoimmunity study in the young (DAISY. Diabetotagia 1996; 39: S07-12.
14. Zicglcr AC, Ziegler R, ardi P,Jackson RA, Soeldncr JS, F.iscnbarth GS. Life table analysis of progression to diabetes of anti-insulin autoantilxKlypositivc relatives of indiuduals with type I diabetes. Diabetes 1989: 38: 1320-5.
15. Falorni A, ortqvist E, Pcrsson B, Lcrnmaik l'_ Radioimmunoassas for glutaiiiic acid decailjox lä se (CAD65 and CAD65 autoantibodies using 3lS or 3H recoinbinant human ligands.y Itrutiuiinl Mftfintls 199j; 18G: S999.
16. Verge CV, Gianani R, Kawasaki E, Yu I., Pictropaolo M,Jackson RA, et al. Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc LA-2 autoantibodies. Diabetes 199(5; 15: 926-33.
17. Gianani R, Rabin DU, Verge CF, Yu I, Babu S, Pictropaolo M, et al. 1CA512 autoantibody radioassay. Diabetes 1995; 11: 13 10-1.
18. Kawasaki E, Yu I, Gianani R, ierge CF, Babu S, Bonifacio E, et al. Ei^ Iuation of islet cell antigen (ICA 512 IA-2 autoantibody radioassays using osetlapping. ICA512 IA-2 constructs. J Clin Kndorrinol Metab 1997; 82: 375-80.
19. Pucher CC, Elliott RB. A sensitive and reproducible method for the assay of human islet cell antibodics.y Immunot Methods 1990; 12'J: 111-7.
20. Bugawan TI, Etlicli HA. Rapid tping of HLA-DQB1 DNA polymorphism using nonradioactivc oligonucleotidc prolcs and ' amplified DNA. mmunngrtirtia 1991; 33: 163-70.
21. Lorenzcn T, Poeiot F, Hougaard P, NcrupJ. Long-term risk oflDDM in . first-degree relatives of patients with IDDM. Diabelolngia 1991: 37: 321-7.
22. Kyvik KO, Green A, Beck-Niclscn H. Tile most recent part of the Danish twin registry. Establishment and analysis of zygote specific twinning rates. Vgt& rLciega 1996; 158: 3156-60.
23. SvcndsenAJ, KrcutzfeldJC, Lund F.B, K-vik KO, Green A. Incidence of juvenile-onset diabetes in Denmark. A prospective registration in the counties of F; n, Kibe, Sonderjylland and Vijlcl. L'gnkr Larger 1997; 159: 1257-60.
24. Johnston C, Pyke DA Cudwortli AG, Wolf F. HLA-DR tping in identical twins with insulin-dependent diabetes: difference between concordant and discordant pairs. BMJ 1983: 286: 253-5.