-
1
-
-
0029021387
-
Late progression to diabetes and evidence for chronic Beta-Cell autoimmunity in identical twins of patients with type 1 diabetes
-
Verge CF, Gianani R, Yu L et al. Late progression to diabetes and evidence for chronic beta-cell autoimmunity in identical twins of patients with type 1 diabetes. Diabetes 1995; 44: 1176-1179.
-
(1995)
Diabetes
, vol.44
, pp. 1176-1179
-
-
Verge, C.F.1
Gianani, R.2
Yu, L.3
-
3
-
-
0242524453
-
The inherited basis of diabetes mellitus Implications for the genetic analysis of complex traits
-
Florez JC, Hirschhorn J, Altshuler D. The inherited basis of diabetes mellitus: implications for the genetic analysis of complex traits. Annu Rev Genomics Hum Genet 2003; 4: 257-291.
-
(2003)
Annu Rev. Genomics. Hum. Genet.
, vol.4
, pp. 257-291
-
-
Florez, J.C.1
Hirschhorn, J.2
Altshuler, D.3
-
4
-
-
0016177620
-
HL-A antigens and diabetes mellitus
-
Nerup J, Platz P, Andersen OO et al. HL-A antigens and diabetes mellitus. Lancet 1974; 2: 864-866.
-
(1974)
Lancet
, vol.2
, pp. 864-866
-
-
Nerup, J.1
Platz, P.2
Andersen, O.O.3
-
5
-
-
0021343570
-
A polymorphic locus near the human insulin gene is associated with Insulin-Dependent diabetes mellitus
-
Bell GI, Horita S, Karam JH. A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus. Diabetes 1984; 33: 176-183.
-
(1984)
Diabetes
, vol.33
, pp. 176-183
-
-
Bell, G.I.1
Horita, S.2
Karam, J.H.3
-
6
-
-
0037648405
-
Association of the T-Cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
Ueda H, Howson JM, Esposito L et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 2003; 423: 506-511.
-
(2003)
Nature
, vol.423
, pp. 506-511
-
-
Ueda, H.1
Howson, J.M.2
Esposito, L.3
-
7
-
-
12144291502
-
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
-
Bottini N, Musumeci L, Alonso A et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 2004; 36: 337-338.
-
(2004)
Nat. Genet.
, vol.36
, pp. 337-338
-
-
Bottini, N.1
Musumeci, L.2
Alonso, A.3
-
8
-
-
8944259914
-
The CTLA-4 gene region of chromosome 2q33 is linked to and associated with type 1 diabetes
-
Nistico L, Buzzetti R, Pritchard LE et al. The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Hum Mol Genet 1996; 5: 1075-1080.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1075-1080
-
-
Nistico, L.1
Buzzetti, R.2
Pritchard, L.E.3
-
9
-
-
0033820560
-
NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans
-
Hill NJ, Lyons PA, Armitage N, Todd JA, Wicker LS, Peterson LB. NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans. Diabetes 2000; 49: 1744-1747.
-
(2000)
Diabetes
, vol.49
, pp. 1744-1747
-
-
Hill, N.J.1
Lyons, P.A.2
Armitage, N.3
Todd, J.A.4
Wicker, L.S.5
Peterson, L.B.6
-
11
-
-
0027933734
-
A Genome-Wide search for human type 1 diabetes susceptibility genes
-
Davies JL, Kawaguchi Y, Bennett ST et al. A genome-wide search for human type 1 diabetes susceptibility genes. Nature 1994; 371: 130-136.
-
(1994)
Nature
, vol.371
, pp. 130-136
-
-
Davies, J.L.1
Kawaguchi, Y.2
Bennett, S.T.3
-
12
-
-
17144452354
-
A search for type 1 diabetes susceptibility genes in families from the United Kingdom
-
Mein CA, Esposito L, Dunn MG et al. A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nat Genet 1998; 19: 297-300.
-
(1998)
Nat. Genet.
, vol.19
, pp. 297-300
-
-
Mein, C.A.1
Esposito, L.2
Dunn, M.G.3
-
13
-
-
17344372511
-
A Second-Generation screen of the human genome for susceptibility to Insulin-Dependent diabetes mellitus IDDM
-
Concannon P, Gogolin-Ewens KJ, Hinds D et al. A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus (IDDM). Nat Genet 1998; 19: 292-296.
-
(1998)
Nat. Genet.
, vol.19
, pp. 292-296
-
-
Concannon, P.1
Gogolin-Ewens, K.J.2
Hinds, D.3
-
14
-
-
0034821661
-
Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families
-
Cox NJ, Wapelhorst B, Morrison VA et al. Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families. Am J Hum Genet 2001; 69: 820-830.
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 820-830
-
-
Cox, N.J.1
Wapelhorst, B.2
Morrison, V.A.3
-
15
-
-
0028070552
-
Genetic mapping of a susceptibility locus for Insulin-Dependent diabetes mellitus on chromosome 11q
-
Hashimoto L, Habita C, Beressi JP et al. Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome 11q. Nature 1994; 371: 161-164.
-
(1994)
Nature
, vol.371
, pp. 161-164
-
-
Hashimoto, L.1
Habita, C.2
Beressi, J.P.3
-
16
-
-
0035212224
-
A genomewide scan for type 1-Diabetes susceptibility in Scandinavian families Identification of new loci with evidence of interactions
-
Nerup J, Pociot F. A genomewide scan for type 1-diabetes susceptibility in Scandinavian families: identification of new loci with evidence of interactions. Am J Hum Genet 2001; 69: 1301-1313.
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 1301-1313
-
-
Nerup, J.1
Pociot, F.2
-
17
-
-
0028871202
-
Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus
-
Bennett ST, Lucassen AM, Gough SC et al. Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus. Nat Genet 1995; 9: 284-292.
-
(1995)
Nat. Genet.
, vol.9
, pp. 284-292
-
-
Bennett, S.T.1
Lucassen, A.M.2
Gough, S.C.3
-
18
-
-
3543046736
-
A functional variant of SUMO4 a new I kappa B alpha modifier is associated with type 1 diabetes
-
Guo D, Li M, Zhang Y et al. A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes. Nat Genet 2004; 36: 837-841.
-
(2004)
Nat. Genet.
, vol.36
, pp. 837-841
-
-
Guo, D.1
Li, M.2
Zhang, Y.3
-
19
-
-
0033634977
-
TAB2 a novel adaptor protein mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
-
Takaesu G, Kishida S, Hiyama A et al. TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. Mol Cell 2000; 5: 649-658.
-
(2000)
Mol. Cell
, vol.5
, pp. 649-658
-
-
Takaesu, G.1
Kishida, S.2
Hiyama, A.3
-
20
-
-
4344712350
-
TAB2 and TAB3 activate the NF-KappaB pathway through binding to polyubiquitin chains
-
Kanayama A, Seth RB, Sun L et al. TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains. Mol Cell 2004; 15: 535-548.
-
(2004)
Mol. Cell
, vol.15
, pp. 535-548
-
-
Kanayama, A.1
Seth, R.B.2
Sun, L.3
-
21
-
-
0033499621
-
NOD mice are defective in proteasome production and activation of NF-KappaB
-
Hayashi T, Faustman D. NOD mice are defective in proteasome production and activation of NF-kappaB. Mol Cell Biol 1999; 19: 8646-8659.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 8646-8659
-
-
Hayashi, T.1
Faustman, D.2
-
22
-
-
0036006693
-
Elevated NF-KappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function
-
Poligone B, Weaver Jr DJ, Sen P, Baldwin Jr AS, Tisch R. Elevated NF-kappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function. J Immunol 2002; 168: 188-196.
-
(2002)
J. Immunol.
, vol.168
, pp. 188-196
-
-
Poligone, B.1
Weaver Jr., D.J.2
Sen, P.3
Baldwin Jr., A.S.4
Tisch, R.5
-
23
-
-
0035424898
-
Dendritic cells from nonobese diabetic mice exhibit a defect in NF-Kappa B regulation due to a hyperactive I kappa B kinase
-
Weaver Jr DJ, Poligone B, Bui T, Abdel-Motal UM, Baldwin Jr AS, Tisch R. Dendritic cells from nonobese diabetic mice exhibit a defect in NF-kappa B regulation due to a hyperactive I kappa B kinase. J Immunol 2001; 167: 1461-1468.
-
(2001)
J. Immunol.
, vol.167
, pp. 1461-1468
-
-
Weaver Jr., D.J.1
Poligone, B.2
Bui, T.3
Abdel-Motal, U.M.4
Baldwin Jr., A.S.5
Tisch, R.6
-
24
-
-
3042740794
-
A 212-kb region on chromosome 6q25 containing the TAB2 gene is associated with susceptibility to type 1 diabetes
-
Owerbach D, Pina L, Gabbay KH. A 212-kb region on chromosome 6q25 containing the TAB2 gene is associated with susceptibility to type 1 diabetes. Diabetes 2004; 53: 1890-1893.
-
(2004)
Diabetes
, vol.53
, pp. 1890-1893
-
-
Owerbach, D.1
Pina, L.2
Gabbay, K.H.3
-
25
-
-
3042644131
-
A M55V polymorphism in a novel SUMO gene SUMO-4 differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus
-
Bohren KM, Nadkarni V, Song JH, Gabbay KH, Owerbach D. A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus. J Biol Chem 2004; 279: 27233-27238.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27233-27238
-
-
Bohren, K.M.1
Nadkarni, V.2
Song, J.H.3
Gabbay, K.H.4
Owerbach, D.5
-
26
-
-
0347917295
-
Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis
-
Karban AS, Okazaki T, Panhuysen CI et al. Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis. Hum Mol Genet 2004; 13: 35-45.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 35-45
-
-
Karban, A.S.1
Okazaki, T.2
Panhuysen, C.I.3
-
27
-
-
0346154591
-
Characterization of a Nuclear-Factor-Kappa B NFkappaB genetic marker in type 1 diabetes T1DM families
-
Gylvin T, Bergholdt R, Nerup J, Pociot F. Characterization of a nuclear-factor-kappa B (NFkappaB) genetic marker in type 1 diabetes (T1DM) families. Genes Immun 2002; 3: 430-432.
-
(2002)
Genes Immun.
, vol.3
, pp. 430-432
-
-
Gylvin, T.1
Bergholdt, R.2
Nerup, J.3
Pociot, F.4
-
28
-
-
0035487255
-
NFkappaB polymorphisms and susceptibility to type 1 diabetes
-
Hegazy DM, O'Reilly DA, Yang BM, Hodgkinson AD, Millward BA, Demaine AG. NFkappaB polymorphisms and susceptibility to type 1 diabetes. Genes Immun 2001; 2: 304-308.
-
(2001)
Genes Immun.
, vol.2
, pp. 304-308
-
-
Hegazy, D.M.1
O'Reilly, D.A.2
Yang, B.M.3
Hodgkinson, A.D.4
Millward, B.A.5
Demaine, A.G.6
-
30
-
-
0025075899
-
The British Diabetic Association - Warren repository
-
Bain SC, Todd JA, Barnett AH. The British Diabetic Association - Warren repository. Autoimmunity 1990; 7: 83-85.
-
(1990)
Autoimmunity
, vol.7
, pp. 83-85
-
-
Bain, S.C.1
Todd, J.A.2
Barnett, A.H.3
-
31
-
-
11044226181
-
A functional polymorphism 1858C/T in the PTPN22 gene is linked and associated with type I diabetes in multiplex families
-
Onengut-Gumuscu S, Ewens KG, Spielman RS, Concannon P. A functional polymorphism (1858C/T) in the PTPN22 gene is linked and associated with type I diabetes in multiplex families. Genes Immun 2004; 5: 678-680.
-
(2004)
Genes Immun.
, vol.5
, pp. 678-680
-
-
Onengut-Gumuscu, S.1
Ewens, K.G.2
Spielman, R.S.3
Concannon, P.4
-
32
-
-
0032231941
-
PedCheck A program for identification of genotype incompatibilities in linkage analysis
-
O'Connell JR, Weeks DE. PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 1998; 63: 259-266.
-
(1998)
Am. J. Hum. Genet.
, vol.63
, pp. 259-266
-
-
O'Connell, J.R.1
Weeks, D.E.2
-
33
-
-
0033910787
-
A test for linkage and association in general pedigrees The pedigree disequilibrium test
-
Martin ER, Monks SA, Warren LL, Kaplan NL. A test for linkage and association in general pedigrees: the pedigree disequilibrium test. Am J Hum Genet 2000; 67: 146-154.
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 146-154
-
-
Martin, E.R.1
Monks, S.A.2
Warren, L.L.3
Kaplan, N.L.4
-
34
-
-
0033927575
-
Removing the sampling restrictions from Family-Based tests of association for a Quantitative-Trait locus
-
Monks SA, Kaplan NL. Removing the sampling restrictions from family-based tests of association for a quantitative-trait locus. Am J Hum Genet 2000; 66: 576-592.
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 576-592
-
-
Monks, S.A.1
Kaplan, N.L.2
-
35
-
-
0041857847
-
Pedigree disequilibrium tests for multilocus haplotypes
-
Dudbridge F. Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol 2003; 25: 115-121.
-
(2003)
Genet. Epidemiol.
, vol.25
, pp. 115-121
-
-
Dudbridge, F.1
-
36
-
-
0036955762
-
Mapping genes for autoimmunity in humans Type 1 diabetes as a model
-
Onengut-Gumuscu S, Concannon P. Mapping genes for autoimmunity in humans: type 1 diabetes as a model. Immunol Rev 2002; 190: 182-194.
-
(2002)
Immunol. Rev.
, vol.190
, pp. 182-194
-
-
Onengut-Gumuscu, S.1
Concannon, P.2
|