Genetic approach for insulin-dependent diabetes mellitus in clinical practice;LA GENETIQUE DU DIABETE INSULINODEPENDANT. INTERET DANS LA PRATIQUE BIOLOGIQUE

Annales de Biologie Clinique

Volumn 55, Issue 6, 1997, Pages 537-544

  Danze, P M ^a   Penet, S ^b   Fajardy, I ^a  

^a LILLE UNIVERSITY HOSPITAL   (France)

^b NONE

Author keywords

Genetic markers; HLA locus; Insulin gene; Insulin dependent diabetes mellitus

Indexed keywords

GENETIC LINKAGE; GENETIC MARKER; HEREDITY; HISTOCOMPATIBILITY GENE; HLA SYSTEM; INSULIN DEPENDENT DIABETES MELLITUS; PATHOPHYSIOLOGY; PREDICTION; REVIEW; AUTOIMMUNITY; CHROMOSOME MAP; GENETICS; HUMAN; IMMUNOLOGY; MAJOR HISTOCOMPATIBILITY COMPLEX;

INSULIN;

AUTOIMMUNITY; CHROMOSOME MAPPING; DIABETES MELLITUS, TYPE 1; GENETIC MARKERS; HUMANS; INSULIN; MAJOR HISTOCOMPATIBILITY COMPLEX;

EID: 0030786072     PISSN: 00033898     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (41)

1. Deschamps, et al. Rôle des facteurs génétiques et immunologiques dans l'étiologie du DID. Schweiz Med Wschr 1990 ; 120 : 46-53.
2. Thorsby E, Ronningen K. Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to type 1 (insulin-dependent) diabetes mellitus. Diabetologia 1993 ; 36 : 371-7.
3. Degos L. Le système HLA. médecine/sciences 1989 ; 11 (suppl. 1) : 20-4.
4. Hors J. HLA et maladies. In : Dausset J, Pla M, eds. HLA complexe majeur d'histocompatibilité. Paris : Flammarion, 1991 : 298-316.
5. Svejgaard AP, Platz P, Ryder LP. HLA and disease : a survey. Immunol Rev 1982 ; 70 : 193-218.
6. Khalil I, Deschamps I, Lepage V, Aladaccak R, Degos L, Hors J. Dose effect of cis and trans encoded HLA-DQαβ heterodimers in IDDM susceptibility. Diabetes 1992 ; 41 : 378-84.
7. Todd JA, Bell JI, McDevitt HO. HLA-DQβ contributes to susceptibility and to resistance to insulin-dependent diabetes mellitus. Nature 1987 ; 329 : 599-604.
8. Like AA, Guberski DL, Butler L. Influence of environmental viral agents on frequency and tempo of diabetes mellitus in BB/Wor rats. Diabetes 1991 ; 40 : 259-62.
9. Erlich HA, Zeidler A, Chang J, et al. HLA class II alleles and susceptibility and resistance to insulin dependent diabetes mellitus in Mexican-American families. Nature Genet 1993 ; 3 : 358-64.
10. Chicz RM, Lane WS, Robinson RA, Trucco M, Strominger JL, Gorga JC. Self peptides bound to the type 1 diabetes associated class II MHC molecules HLA-DQ1 and HLA-DQ8. Int J Immunol 1994 ; 11 : 1639-49.
11. Tait BD, Drummond BP, Varney MD, Harrison LC. HLA-DRB1*0401 is associated with susceptibility to insulin-dependent diabetes mellitus independently of the DQB1 locus. Eur J Immunogenet 1995 ; 22 : 289-97.
12. Noble JA, Valdes AM, Cook M, Klitz W, Thomson G, Erlich HA. The role of HLA class II genes in IDDM : molecular analysis of 180 caucasian multiplex families. Am J Hum Genet 1996 ; 59 : 1134-48.
13. Briggs D, Stephens C, Vaughan R, Welsh K, Black C. A molecular and serologic analysis of the major histocompatibility complex and complement component C4 in systemic sclerosis. Arthritis-Rheum 1993 ; 36 : 943-54.
14. Ilonen J, Merivuori H, Reijonen H, et al. Tumour necrosis factor-beta gene RFLP alleles in finnish IDDM haplotypes. The Childhood Diabetes in Finland (DiMe) Study Group. Scand J Immunol 1992 ; 36 : 779-83.
15. Jasinski M, Wieckiewicz J, Ruggiero I, Pituch-Noworolska A, Zembala M. Isotype specific regulation of MHC class II gene expression in human monocytes by exogenous and endogenous tumor necrosis factor. J Clin Immunol 1995 ; 15 : 185-93.
16. Cascino I, Sorrentino R, Tosi R. Strong genetic association between HLA-DR3 and a polymorphic variation in the regulatory region of the HSP70-1 gene. Immunogenetics 1993 ; 37 : 177-82.
17. Mignot E, Kimura A, Abbal M, et al. DQCAR microsatellite polymorphisms in three selected HLA class II-associated diseases. Tissue-Antigens 1995 ; 46 : 299-304.
18. Caillat-Zucman S, Bertin E, Timsit J, Boitard C, Assan E, Bach JF. TAP1 and TAP2 transporter genes and predisposition to IDDM. Acad Sci Paris 1992 ; t. 315 série III : 535-9.
19. Ploski R, Undlien DE, Vinje O, Forre O, Thorsby E, Ronningen KS. Polymorphism of human major histocompatibility complex-encoded transporter associated with antigen processing (TAP) genes and susceptibility to juvenile rheumatoid arthritis. Hum Immunol 1994 ; 39 : 54-60.
20. Ronningen KS, Undlien DE, Ploski R, et al. Linkage disequilibrium between TAP2 variants and HLA class II alleles ; no primary association between TAP2 variants and insulin-dependent diabetes mellitus. Eur J Immunol 1993 ; 23 : 1050-6.
21. Shield JP, Wadsworth EJ, Baum JD. The genetic contribution to disease pathogenesis in childhood diabetes is greatest in the very young. Diabet Med 1995 ; 12 : 377-9.
22. Honeyman MC, Harrison LC, Drummond B, Colman PG, Tait BD. Analysis of families at risk for insulin-dependent diabetes mellitus reveals that HLA antigens influence progression to clinical disease. Mol Med 1995 ; 1 : 576-82.
23. Demaine AG, Hibbert ML, Mangles D, Millward BA. A new marker in the HLA class I region is associated with the age of onset of IDDM. Diabetologia 1995 ; 38 : 623-8.
24. Kobayashi T, Tamemoto K, Nakanishi K, et al. Immunogenetic and clinical characterization of slowly progressive IDDM. Diabetes Care 1993 ; 16 : 780-8.
25. Agardh D, Gaur LK, Agardh E, Landin-Olsson M, Agardh CD, Lernmark A. HLA-DQB1*0201/*0302 is associated with severe retinopathy in patients with IDDM. Diahetologia 1996 ; 39 : 1313-7.
26. Deschamps I, Hors J, Clerget-Darpoux F, et al. Excess of Maternal HLADR3 antigens in HLA DR3,4 positive type 1 diabetic patients. Diabetologia 1990 ; 33 : 425-30.
27. Clerget-Darpoux F, Babron MC, Daschamps I, Hors J. Complementation and maternal effect in IDDM. Am J Hum Genet 1991 ; 49 : 42-8.
28. Field LL. Non-HLA region genes in insulin dependent diabetes mellitus. Baillieres's Clin Endocrinol Metab 1991 ; 5 : 413-36.
29. Faas S, Trucco M. The genes influencing the susceptibility to IDDM in humans. J Endocrinol Invest 1994 ; 17 : 477-95.
30. Garchon HJ, Bach JF. The contribution of non-MHC genes to susceptibility to autoimmune diseases. Hum Immunol 1991 ; 32 : 1-30.
31. Lucassen AM, Julier C, Beressi JP, Froguel P, Lathrop M, Bell JI. Susceptibility to insulin-dependent diabetes mellitus maps to 4.1 kb segment of DNA spanning the insulin gene and associated VNTR. Nature Genet 1993 ; 4 : 305-10.
32. Julier C, Hyer RN, Davies J, et al. Insulin-IGF2 region on 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility. Nature 1991 ; 354 : 155-9.
33. Aitman TJ, Todd JA. Molecular genetics of diabetes. Baillieres's Clin Endocrinol Metab 1995 ; 9 : 631-56.
34. Owerbach D, Gabbay KH. Localization of a diabetes type 1 susceptibilty locus to the variable tandem repeat region flanking the insulin gene. Diabetes 1993 ; 42 : 1708-14.
35. Bennet ST, Lucassen AM, Gough SCL, et al. Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus. Nature Genet 1995 ; 9 : 284-92.
36. Todd JA, Aitman TJ, Cornall RJ, et al. Genetic analysis of autoimmun type 1 diabetes mellitus in mice. Nature 1991 ; 351 : 542-7.
37. Davies JL, Kawaguchi Y, Bennett ST, et al. A genome-wide search for human type 1 diabetes susceptibility genes. Nature 1994 ; 371 : 130-6.
38. Todd JA. Genetic analysis of type 1 diabetes using whole genome approaches. Proc Natl Acad Sci USA 1995 ; 95 : 8560-5.
39. Cordell HJ, Todd JA. Multifactorial inheritance in type 1 diabetes. Trends in Genet 1995 ; 11 : 499-504.
40. Bougneres P, Caillat-Zucman S. Gènes de susceptibilité au diabète de type 1. Médecine Thérapeutique 1995 ; 1 : 143-52.
41. Doria A, Lee J, Krolewski AS. Diabetes susceptibility at IDDM2 cannot be positively mapped to the VNTR locus of the insulin gene. Diabetalogia 1996 ; 39 : 594-9.