메뉴 건너뛰기




Volumn 41, Issue 2, 2005, Pages 141-149

Hypothesis for the pathogenesis of type 1A diabetes

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; GLUTAMATE DECARBOXYLASE 65; HLA ANTIGEN; HLA DQ ANTIGEN; HLA DR ANTIGEN; INSULIN; INTERLEUKIN 13; PANCREAS ISLET CELL ANTIBODY; POLYCYTIDYLIC ACID; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; VITAMIN D RECEPTOR;

EID: 16244420705     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: 10.1358/dot.2005.41.2.882664     Document Type: Review
Times cited : (4)

References (58)
  • 2
    • 0022617990 scopus 로고
    • Type-1 diabetes-mellitus - A chronic autoimmune-disease
    • Eisenbarth, G. Type-1 diabetes-mellitus - A chronic autoimmune-disease. New Engl J Med 1986, 314: 1360-8.
    • (1986) New Engl J Med , vol.314 , pp. 1360-1368
    • Eisenbarth, G.1
  • 3
    • 0041519032 scopus 로고    scopus 로고
    • Genetics of type 1A (immune mediated) diabetes
    • Melanitou, E., Fain, P., Eisenbarth, G.S. Genetics of type 1A (immune mediated) diabetes. J Autoimm 2003, 21: 93-8.
    • (2003) J Autoimm , vol.21 , pp. 93-98
    • Melanitou, E.1    Fain, P.2    Eisenbarth, G.S.3
  • 4
    • 0029995958 scopus 로고    scopus 로고
    • Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2autoantibodies
    • Verge, C.F., Gianani, R., Kawasaki, E. et al. Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2autoantibodies. Diab 1996, 45: 926-33.
    • (1996) Diab , vol.45 , pp. 926-933
    • Verge, C.F.1    Gianani, R.2    Kawasaki, E.3
  • 5
    • 0031738116 scopus 로고    scopus 로고
    • Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial islet autoantibody workshop
    • Verge, C.F., Stenger, D., Bonifacio, E. et al. Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial islet autoantibody workshop. Diab 1998, 47: 1857-66.
    • (1998) Diab , vol.47 , pp. 1857-1866
    • Verge, C.F.1    Stenger, D.2    Bonifacio, E.3
  • 6
    • 1842334456 scopus 로고    scopus 로고
    • Report of the expert committee on the diagnosis and classification of diabetes mellitus
    • American Diabetes Association. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diab Care 1997, 20: 1183-97.
    • (1997) Diab Care , vol.20 , pp. 1183-1197
  • 8
    • 0038303191 scopus 로고    scopus 로고
    • The role of T-cells in the pathogenesis of Type 1 diabetes: From cause to cure
    • Roep, B.O. The role of T-cells in the pathogenesis of Type 1 diabetes: From cause to cure. Diab 2003, 46: 305-21.
    • (2003) Diab , vol.46 , pp. 305-321
    • Roep, B.O.1
  • 9
    • 0036104602 scopus 로고    scopus 로고
    • Juvenile autoimmune diabetes: A pathogenic role for maternal antibodies?
    • von Herrath, M., Bach, J.F. Juvenile autoimmune diabetes: A pathogenic role for maternal antibodies? Nat Med 2002, 8: 331-3.
    • (2002) Nat Med , vol.8 , pp. 331-333
    • Von Herrath, M.1    Bach, J.F.2
  • 10
    • 0036116272 scopus 로고    scopus 로고
    • Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice
    • Greeley, S.A., Katsumata, M., Yu, L. et al. Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice. Nat Med 2002, 8: 399-402.
    • (2002) Nat Med , vol.8 , pp. 399-402
    • Greeley, S.A.1    Katsumata, M.2    Yu, L.3
  • 11
    • 8544271680 scopus 로고    scopus 로고
    • Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice
    • Akashi, T., Nagafuchi, S., Anzai, K. et al. Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice, Int Immunol 1997, 9: 1159-64.
    • (1997) Int Immunol , vol.9 , pp. 1159-1164
    • Akashi, T.1    Nagafuchi, S.2    Anzai, K.3
  • 12
    • 0027420431 scopus 로고
    • HLA-DQ primarily confers protection and HLA-DR susceptibility in type I (insulin-dependent) diabetes studied in population-based affected families and controls
    • Kockum, I., Wassmuth, R., Holmberg, E., Michelsen, B., Lernmark, A. HLA-DQ primarily confers protection and HLA-DR susceptibility in type I (insulin-dependent) diabetes studied in population-based affected families and controls. Am J Hum Genet 1993, 53: 150-67.
    • (1993) Am J Hum Genet , vol.53 , pp. 150-167
    • Kockum, I.1    Wassmuth, R.2    Holmberg, E.3    Michelsen, B.4    Lernmark, A.5
  • 13
    • 0029021387 scopus 로고
    • Late progression to diabetes and evidence for chronic b-cell autoimmunity in identical twins of patients with type I diabetes
    • Verge, C.F., Gianani, R., Yu, L. et al. Late progression to diabetes and evidence for chronic b-cell autoimmunity in identical twins of patients with type I diabetes. Diab 1995, 44: 1176-9.
    • (1995) Diab , vol.44 , pp. 1176-1179
    • Verge, C.F.1    Gianani, R.2    Yu, L.3
  • 14
    • 0030175880 scopus 로고    scopus 로고
    • Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specificities determines risk of type I diabetes
    • Verge, C.F., Gianani, R., Kawasaki, E. et al. Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specificities determines risk of type I diabetes. J Autoimmun 1996, 9: 379-83.
    • (1996) J Autoimmun , vol.9 , pp. 379-383
    • Verge, C.F.1    Gianani, R.2    Kawasaki, E.3
  • 15
    • 0031805432 scopus 로고    scopus 로고
    • Ketoacidosis occurring in newly diagnosed and established diabetic children
    • Smith, C.P., Firth, D., Bennett, S., Howard, C., Chisholm, P. Ketoacidosis occurring in newly diagnosed and established diabetic children. Act Paediatr 1998, 87: 537-41.
    • (1998) Act Paediatr , vol.87 , pp. 537-541
    • Smith, C.P.1    Firth, D.2    Bennett, S.3    Howard, C.4    Chisholm, P.5
  • 16
    • 0036263450 scopus 로고    scopus 로고
    • The diabetes-prone BB rat carries a frameshift mutation in Ian4, a positional candidate of Iddm1
    • Hornum, L., Romer, J., Markholst, H. The diabetes-prone BB rat carries a frameshift mutation in Ian4, a positional candidate of Iddm1. Diab 2002, 51: 1972-9.
    • (2002) Diab , vol.51 , pp. 1972-1979
    • Hornum, L.1    Romer, J.2    Markholst, H.3
  • 17
    • 0036699521 scopus 로고    scopus 로고
    • Cblb is a major susceptibility gene for rat type 1 diabetes mellitus
    • Yokoi, N., Komeda, K., Wang, H.Y. et al. Cblb is a major susceptibility gene for rat type 1 diabetes mellitus. Nat Genet 2002, 31: 391-4.
    • (2002) Nat Genet , vol.31 , pp. 391-394
    • Yokoi, N.1    Komeda, K.2    Wang, H.Y.3
  • 18
    • 0036081840 scopus 로고    scopus 로고
    • APS-I/APECED: The clinical disease and therapy
    • Eisenbarth, G.S. (Ed.). W.B. Saunders Company, Philadelphia
    • Perheentupa, J. APS-I/APECED: The clinical disease and therapy. In: Eisenbarth, G.S. (Ed.). Autoimmune polyendocrine syndromes. W.B. Saunders Company, Philadelphia 2002; 295-320.
    • (2002) Autoimmune Polyendocrine Syndromes , pp. 295-320
    • Perheentupa, J.1
  • 19
    • 0035163909 scopus 로고    scopus 로고
    • X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
    • Wildin, R.S., Ramsdell, F., Peake, J. et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet 2001, 27: 18-20.
    • (2001) Nat Genet , vol.27 , pp. 18-20
    • Wildin, R.S.1    Ramsdell, F.2    Peake, J.3
  • 20
    • 0037112047 scopus 로고    scopus 로고
    • Projection of an immunological self-shadow within the thymus by the aire protein
    • Anderson, M.S., Venanzi, E.S., Klein, L. et al. Projection of an immunological self-shadow within the thymus by the aire protein. Science 2002, 298: 1395-1401.
    • (2002) Science , vol.298 , pp. 1395-1401
    • Anderson, M.S.1    Venanzi, E.S.2    Klein, L.3
  • 21
    • 0038434099 scopus 로고    scopus 로고
    • Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis
    • Gambineri, E., Torgerson, T.R., Ochs, H.D. Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis. Curr Opin Rheumatol 2003, 15: 430-5.
    • (2003) Curr Opin Rheumatol , vol.15 , pp. 430-435
    • Gambineri, E.1    Torgerson, T.R.2    Ochs, H.D.3
  • 22
    • 0029953008 scopus 로고    scopus 로고
    • The role of HLA class II genes in insulin-dependent diabetes mellitus: Molecular analysis of 180 Caucasian, multiplex families
    • Noble, J.A., Valdes, A.M., Cook, M., Klitz, W., Thomson, G., Erlich, H.A. The role of HLA class II genes in insulin-dependent diabetes mellitus: Molecular analysis of 180 Caucasian, multiplex families. Am J Hum Genet 1996, 59: 1134-48.
    • (1996) Am J Hum Genet , vol.59 , pp. 1134-1148
    • Noble, J.A.1    Valdes, A.M.2    Cook, M.3    Klitz, W.4    Thomson, G.5    Erlich, H.A.6
  • 23
    • 0036197220 scopus 로고    scopus 로고
    • Millennium award recipient contribution. Identification of children with early onset and high incidence of anti-islet autoantibodies
    • Robles, D.T., Eisenbarth, G.S., Wang, T. et al. Millennium award recipient contribution. Identification of children with early onset and high incidence of anti-islet autoantibodies. Clin Immunol 2002, 102: 217-24.
    • (2002) Clin Immunol , vol.102 , pp. 217-224
    • Robles, D.T.1    Eisenbarth, G.S.2    Wang, T.3
  • 24
    • 0032030625 scopus 로고    scopus 로고
    • A peptide binding motif for HLA-DQA1*0102/DQB1*0602, the class II MHC molecule associated with dominant protection in insulin-dependent diabetes mellitus
    • Ettinger, R.A., Kwok, W.W. A peptide binding motif for HLA-DQA1*0102/DQB1*0602, the class II MHC molecule associated with dominant protection in insulin-dependent diabetes mellitus. J Immunol 1998, 160: 2365-73.
    • (1998) J Immunol , vol.160 , pp. 2365-2373
    • Ettinger, R.A.1    Kwok, W.W.2
  • 25
    • 0026641354 scopus 로고
    • Concordance for type 1 (Insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland
    • Kaprio, J., Tuomilehto, J., Koskenvuo, M. et al. Concordance for type 1 (Insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland. Diabetologia 1992, 35: 1060-7.
    • (1992) Diabetologia , vol.35 , pp. 1060-1067
    • Kaprio, J.1    Tuomilehto, J.2    Koskenvuo, M.3
  • 26
    • 0028075495 scopus 로고
    • Non-genetic risk determinants of type 1 diabetes
    • Dahlquist, G. Non-genetic risk determinants of type 1 diabetes. Diab Metab 1994, 20: 251-7.
    • (1994) Diab Metab , vol.20 , pp. 251-257
    • Dahlquist, G.1
  • 27
    • 0031944926 scopus 로고    scopus 로고
    • A functional analysis of the role of IGF2 in IDDM2-encoded susceptibility to type 1 diabetes
    • Vafiadis, P., Grabs, R., Goodyer, C.G., Colle, E., Polychronakos, C. A functional analysis of the role of IGF2 in IDDM2-encoded susceptibility to type 1 diabetes. Diab 1998, 47: 831-6.
    • (1998) Diab , vol.47 , pp. 831-836
    • Vafiadis, P.1    Grabs, R.2    Goodyer, C.G.3    Colle, E.4    Polychronakos, C.5
  • 28
    • 0035345428 scopus 로고    scopus 로고
    • Concordance for type 1 diabetes in identical twins is affected by insulin genotype
    • Metcalfe, K.A., Hitman, G.A., Rowe, R.E. et al. Concordance for type 1 diabetes in identical twins is affected by insulin genotype. Diab Care 2001, 24: 838-42.
    • (2001) Diab Care , vol.24 , pp. 838-842
    • Metcalfe, K.A.1    Hitman, G.A.2    Rowe, R.E.3
  • 31
    • 0042839568 scopus 로고    scopus 로고
    • Hole of cytokines in the pathogenesis of autoimmune diabetes mellitus
    • Rabinovitch, A., Suárez-Pinzon, W.L. Hole of cytokines in the pathogenesis of autoimmune diabetes mellitus. Rev Endocr Metabol Dis 2003, 4:291-9.
    • (2003) Rev Endocr Metabol Dis , vol.4 , pp. 291-299
    • Rabinovitch, A.1    Suárez-Pinzon, W.L.2
  • 33
    • 0034569180 scopus 로고    scopus 로고
    • Increased prevalence of autoimmune thyroid disease in patients with type 1 diabetes
    • Park, Y.S., Kim, T.W., Kim, W.B., Cho, B.Y. Increased prevalence of autoimmune thyroid disease in patients with type 1 diabetes. Korean J Intern Med 2000, 15: 202-10.
    • (2000) Korean J Intern Med , vol.15 , pp. 202-210
    • Park, Y.S.1    Kim, T.W.2    Kim, W.B.3    Cho, B.Y.4
  • 34
    • 0242383232 scopus 로고    scopus 로고
    • Autoimmune thyroid dysfunction in children with type 1 diabetes mellitus: Screening guidelines based on a retrospective analysis
    • Bilimoria, K.Y., Pescovitz, O.H., DiMeglio, L.A. Autoimmune thyroid dysfunction in children with type 1 diabetes mellitus: Screening guidelines based on a retrospective analysis. J Pediatr Endocrinol Metab 2003, 16: 1111-7.
    • (2003) J Pediatr Endocrinol Metab , vol.16 , pp. 1111-1117
    • Bilimoria, K.Y.1    Pescovitz, O.H.2    DiMeglio, L.A.3
  • 36
    • 0018829015 scopus 로고
    • Adrenal autoantibodies and Addison disease in insulin-dependent diabetes mellitus
    • Riley, W.J., Maclaren, N.K., Neufeld, M. Adrenal autoantibodies and Addison disease in insulin-dependent diabetes mellitus. J Pediatr 1980, 97: 191-5.
    • (1980) J Pediatr , vol.97 , pp. 191-195
    • Riley, W.J.1    Maclaren, N.K.2    Neufeld, M.3
  • 38
    • 0036148871 scopus 로고    scopus 로고
    • Insulin specific tolerance in diabetes
    • Gottlieb, P.A., Eisenbarth, G.S. Insulin specific tolerance in diabetes. Clin Immunol 2002, 102: 2-11.
    • (2002) Clin Immunol , vol.102 , pp. 2-11
    • Gottlieb, P.A.1    Eisenbarth, G.S.2
  • 39
    • 4243595317 scopus 로고    scopus 로고
    • Induction of autoantibodies to native insulin in normal and NOD derived mice following immunization with the immunodominant self-B-chain insulin peptide B:9-23
    • Abiru, N., Yu, L., Wegmann, D., Eisenbarth, G.S. Induction of autoantibodies to native insulin in normal and NOD derived mice following immunization with the immunodominant self-B-chain insulin peptide B:9-23. Diabetes 2000; 49 (Suppl. 1): A232.
    • (2000) Diabetes , vol.49 , Issue.SUPPL. 1
    • Abiru, N.1    Yu, L.2    Wegmann, D.3    Eisenbarth, G.S.4
  • 40
    • 0033856357 scopus 로고    scopus 로고
    • Dual overlapping peptides recognized by insulin peptide B:9-23 reactive T cell receptor AV13S3 T cell clones of the NOD mouse
    • Abiru, N., Wegmann, D., Kawasaki, E., Gottlieb, P., Simone, E., Eisenbarth, G.S. Dual overlapping peptides recognized by insulin peptide B:9-23 reactive T cell receptor AV13S3 T cell clones of the NOD mouse. J Autoimmun 2000, 14:231-7.
    • (2000) J Autoimmun , vol.14 , pp. 231-237
    • Abiru, N.1    Wegmann, D.2    Kawasaki, E.3    Gottlieb, P.4    Simone, E.5    Eisenbarth, G.S.6
  • 41
    • 0030962478 scopus 로고    scopus 로고
    • T cell receptor restriction of diabetogenic autoimmune NOD T cells
    • Simone, E., Daniel, D., Schloot, N. et al. T cell receptor restriction of diabetogenic autoimmune NOD T cells. Proc Natl Acad Sci USA 1997, 94: 2518-21.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2518-2521
    • Simone, E.1    Daniel, D.2    Schloot, N.3
  • 42
    • 0037117454 scopus 로고    scopus 로고
    • Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidylic acid) and an insulin self-peptide
    • Moriyama, H., Wen, L., Abiru, N. et al. Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidylic acid) and an insulin self-peptide. Proc Natl Acad Sci USA 2002, 99: 5539-44.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 5539-5544
    • Moriyama, H.1    Wen, L.2    Abiru, N.3
  • 43
    • 0042638687 scopus 로고    scopus 로고
    • Testing the hypothesis that the insulin 1 gene is essential for diabetogenesis and knockout of insulin 2 gene accelerates diabetes in NOD mice
    • Moriyama, H., Paronen, J., Liu, E. et al. Testing the hypothesis that the insulin 1 gene is essential for diabetogenesis and knockout of insulin 2 gene accelerates diabetes in NOD mice. Diabetes Metabol Res Rev 2002,18 (Suppl. 4): S26.
    • (2002) Diabetes Metabol Res Rev , vol.18 , Issue.SUPPL. 4
    • Moriyama, H.1    Paronen, J.2    Liu, E.3
  • 44
    • 0038345163 scopus 로고    scopus 로고
    • A functional polymorphism in the promoter/enhancer region of the FOXP3/Scurfin gene associated with type 1 diabetes
    • Bassuny, W.M., Ihara, K., Sasaki, Y. et al. A functional polymorphism in the promoter/enhancer region of the FOXP3/Scurfin gene associated with type 1 diabetes, Immunogenetics 2003, 55: 149-56.
    • (2003) Immunogenetics , vol.55 , pp. 149-156
    • Bassuny, W.M.1    Ihara, K.2    Sasaki, Y.3
  • 45
    • 0030707588 scopus 로고    scopus 로고
    • Cytokine- and costimulation-mediated therapy of IDDM
    • Cameron, M.J., Arreaza, G.A., Delovitch, T.L. Cytokine- and costimulation-mediated therapy of IDDM. Grit Rev Immunol 1997, 17: 537-44.
    • (1997) Grit Rev Immunol , vol.17 , pp. 537-544
    • Cameron, M.J.1    Arreaza, G.A.2    Delovitch, T.L.3
  • 46
    • 0141816761 scopus 로고    scopus 로고
    • Timing of initial cereal exposure in infancy and risk of islet autoimmunity
    • Norris, J.M., Barriga, K., Klingensmith, G. et al. Timing of initial cereal exposure in infancy and risk of islet autoimmunity. JAMA 2003, 290: 1713-20.
    • (2003) JAMA , vol.290 , pp. 1713-1720
    • Norris, J.M.1    Barriga, K.2    Klingensmith, G.3
  • 47
    • 0017817291 scopus 로고
    • Rubella infection and diabetes mellitus
    • Menser, M.A., Forrest, J.M., Bransby, R.D. Rubella infection and diabetes mellitus. Lancet 1978, 1:57-60.
    • (1978) Lancet , vol.1 , pp. 57-60
    • Menser, M.A.1    Forrest, J.M.2    Bransby, R.D.3
  • 48
    • 0034982992 scopus 로고    scopus 로고
    • Type 1A diabetes induced by infection and immunization
    • Rubles, D.T., Eisenbarth, G.S. Type 1A diabetes induced by infection and immunization. J Autoimmun 2001, 16: 355-62.
    • (2001) J Autoimmun , vol.16 , pp. 355-362
    • Rubles, D.T.1    Eisenbarth, G.S.2
  • 49
    • 0344765489 scopus 로고    scopus 로고
    • Coxsackie B virus infection and beta cell autoantibodies in newly diagnosed IDDM adult patients
    • Andreoletti, L., Hober, D., Hober-Vandenberghe, C. et al. Coxsackie B virus infection and beta cell autoantibodies in newly diagnosed IDDM adult patients. Clin Diagn Virol 1998, 9: 125-33.
    • (1998) Clin Diagn Virol , vol.9 , pp. 125-133
    • Andreoletti, L.1    Hober, D.2    Hober-Vandenberghe, C.3
  • 50
    • 0034120066 scopus 로고    scopus 로고
    • Increased level of interferon-alpha in blood of patients with insulin-dependent diabetes mellitus: Relationship with coxsackievirus B infection
    • Chehadeh, W., Weill, J., Vantyghem, M.C. et al. Increased level of interferon-alpha in blood of patients with insulin-dependent diabetes mellitus: relationship with coxsackievirus B infection. J Infect Dis 2000, 181: 1929-39.
    • (2000) J Infect Dis , vol.181 , pp. 1929-1939
    • Chehadeh, W.1    Weill, J.2    Vantyghem, M.C.3
  • 51
    • 0036158287 scopus 로고    scopus 로고
    • Enterovirus infection can induce immune responses that cross-react with beta-cell autoantigen tyrosine phosphatase IA-2/ IAR
    • Harkonen, T., Lankinen, H., Davydova, B., Hovi, T., Roivainen, M. Enterovirus infection can induce immune responses that cross-react with beta-cell autoantigen tyrosine phosphatase IA-2/ IAR. J Med Virol 2002, 66: 340-50.
    • (2002) J Med Virol , vol.66 , pp. 340-350
    • Harkonen, T.1    Lankinen, H.2    Davydova, B.3    Hovi, T.4    Roivainen, M.5
  • 52
    • 0343618660 scopus 로고    scopus 로고
    • Enterovirus RNA in serum is a risk factor for beta-cell autoimmunity and clinical type 1 diabetes: A prospective study
    • Childhood diabetes in Finland (DiMe) Study Group
    • Lonnrot, M., Salminen, K., Knip, M. et al. Enterovirus RNA in serum is a risk factor for beta-cell autoimmunity and clinical type 1 diabetes: A prospective study. Childhood diabetes in Finland (DiMe) Study Group. J Med Virol 2000, 61: 214-20.
    • (2000) J Med Virol , vol.61 , pp. 214-220
    • Lonnrot, M.1    Salminen, K.2    Knip, M.3
  • 53
    • 8944258928 scopus 로고    scopus 로고
    • Newborn screening for HLA markers associated with IDDM: Diabetes autoimmunity study in the young (DAISY)
    • Rewers, M., Bugawan, T.L., Norris, J.M. et al. Newborn screening for HLA markers associated with IDDM: Diabetes autoimmunity study in the young (DAISY). Diabetol 1996, 39: 807-12.
    • (1996) Diabetol , vol.39 , pp. 807-812
    • Rewers, M.1    Bugawan, T.L.2    Norris, J.M.3
  • 54
    • 0031025574 scopus 로고    scopus 로고
    • Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice
    • French, M.B., Allison, J., Cram, D.S. et al. Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice. Diab 1997, 46: 34-9.
    • (1997) Diab , vol.46 , pp. 34-39
    • French, M.B.1    Allison, J.2    Cram, D.S.3
  • 55
    • 0038326717 scopus 로고    scopus 로고
    • Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes
    • Steptoe, R.J., Ritchie, J.M., Harrison, L.C. Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes. J Clin Invest 2003, 111: 1357-63.
    • (2003) J Clin Invest , vol.111 , pp. 1357-1363
    • Steptoe, R.J.1    Ritchie, J.M.2    Harrison, L.C.3
  • 56
    • 0033001488 scopus 로고    scopus 로고
    • The NOD mouse model of type 1 diabetes: As good as it gets?
    • Atkinson, M.A., Leiter, E.H. The NOD mouse model of type 1 diabetes: As good as it gets? Nat Med 1999, 5: 601-4.
    • (1999) Nat Med , vol.5 , pp. 601-604
    • Atkinson, M.A.1    Leiter, E.H.2
  • 57
    • 0029616384 scopus 로고
    • The Diabetes Prevention Trial-Type 1 diabetes (DPT-1). Implementation of screening and staging of relatives
    • DPT-1 Study Group
    • The Diabetes Prevention Trial-Type 1 diabetes (DPT-1). Implementation of screening and staging of relatives. DPT-1 Study Group. Transplant Proc 1995, 27: 3377.
    • (1995) Transplant Proc , vol.27 , pp. 3377
  • 58
    • 0037198420 scopus 로고    scopus 로고
    • Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
    • Herold, K.C., Hagopian, W., Auger, J.A. et al. Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N Engl J Med 2002, 346: 1692-8.
    • (2002) N Engl J Med , vol.346 , pp. 1692-1698
    • Herold, K.C.1    Hagopian, W.2    Auger, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.