PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression

Journal of Biological Chemistry

Volumn 283, Issue 25, 2008, Pages 17702-17711

  Nakamura, Kyoko ^a   Sakaue, Hiroshi ^a,e   Nishizawa, Akihiko ^a   Matsuki, Yasushi ^b   Gomi, Hideyuki ^b   Watanabe, Eijiro ^b   Hiramatsu, Ryuji ^b   Tamamori Adachi, Mimi ^c   Kitajima, Shigetaka ^c   Noda, Tetsuo ^d   Ogawa, Wataru ^a   Kasuga, Masato ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d CANCER INSTITUTE   (Japan)

^e KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL PROLIFERATION; CELLS; GENE TRANSFER; NUCLEIC ACIDS; RNA;

CELL CYCLE CONTROLS; CELL CYCLES; CRE RECOMBINASE; FORCED EXPRESSIONS; GAIN INSIGHTS; GLYCOGEN SYNTHASE KINASES; GROWTH FACTORS; IN CELLS; MOUSE EMBRYONIC FIBROBLASTS; OVEREXPRESSION; PHOSPHOINOSITIDE; PROTEIN KINASES; RIBOSOMAL PROTEINS; RNA INTERFERENCES; S-PHASE; S6 KINASES;

CYTOLOGY;

CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; GLYCOGEN SYNTHASE KINASE 3; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; DNA; OLIGONUCLEOTIDE;

ALLELE; ANIMAL CELL; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE; MOUSE; NONHUMAN; PDK1 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; ADENOVIRUS; ANIMAL; APOPTOSIS; BIOLOGICAL MODEL; CELL CYCLE; CHEMISTRY; FIBROBLAST; HOMOZYGOTE; METABOLISM; MOUSE MUTANT; TIME;

MUS;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DNA; FIBROBLASTS; HOMOZYGOTE; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; OLIGONUCLEOTIDES; TIME FACTORS;

EID: 47749122567     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M802589200     Document Type: Article

References (74)

1. Alessi, D. R., James, S. R., Downes, C. P., Holmes, A. B., Gaffney, P. R., Reese, C. B., and Cohen, P. (1997) Curr. Biol. 7, 261-269
2. Stokoe, D., Stephens, L. R., Copeland, T., Gaffney, P. R., Reese, C. B., Painter, G. F., Holmes, A. B., McCormick, F., and Hawkins, P. T. (1997) Science 277, 567-570
3. Williams, M. R., Arthur, J. S., Balendran, A., van der Kaay, J., Poli, V., Cohen, P., and Alessi, D. R. (2000) Curr. Biol. 10, 439-448
4. Jensen, C. J., Buch, M. B., Krag, T. O., Hemmings, B. A., Gammeltoft, S., and Frodin, M. (1999) J. Biol. Chem. 274, 27168-27176
5. Richards, S. A., Fu, J., Romanelli, A., Shimamura, A., and Blenis, J. (1999) Curr. Biol. 9, 810-820
6. Newton, A. C. (2003) Biochem. J. 370, 361-371
7. Kobayashi, T., and Cohen, P. (1999) Biochem. J. 339, 319-328
8. Collins, B. J., Deak, M., Arthur, J. S., Armit, L. J., and Alessi, D. R. (2003) EMBO J. 22, 4202-4211
9. Casamayor, A., Torrance, P. D., Kobayashi, T., Thorner, J., and Alessi, D. R. (1999) Curr. Biol. 9, 186-197
10. Inagaki, M., Schmelzle, T., Yamaguchi, K., Irie, K., Hall, M. N., and Matsumoto, K. (1999) Mol. Cell. Biol. 19, 8344-8352
11. Niederberger, C., and Schweingruber, M. E. (1999) Mol. Gen. Genet. 261, 177-183
12. Paradis, S., Ailion, M., Toker, A., Thomas, J. H., and Ruvkun, G. (1999) Genes Dev. 13, 1438-1452
13. Cho, K. S., Lee, J. H., Kim, S., Kim, D., Koh, H., Lee, J., Kim, C., Kim, J., and Chung, J. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 6144-6149
14. Rintelen, F., Stocker, H., Thomas, G., and Hafen, E. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 15020-15025
15. Lawlor, M. A., Mora, A., Ashby, P. R., Williams, M. R., Murray-Tait, V., Malone, L., Prescott, A. R., Lucocq, J. M., and Alessi, D. R. (2002) EMBO J. 21, 3728-3738
16. Hinton, H. J., Alessi, D. R., and Cantrell, D. A. (2004) Nat. Immunol. 5, 539-545
17. Sato, S., Fujita, N., and Tsuruo, T. (2002) Oncogene 21, 1727-1738
18. Bilanges, B., and Stokoe, D. (2005) Biochem. J. 388, 573-583
19. Wick, M. J., Wick, K. R., Chen, H., He, H., Dong, L. Q., Quon, M. J., and Liu, F. (2002) J. Biol. Chem. 277, 16632-16638
20. Inoue, H., Ogawa, W., Asakawa, A., Okamoto, Y., Nishizawa, A., Matsumoto, M., Teshigawara, K., Matsuki, Y., Watanabe, E., Hiramatsu, R., Notohara, K., Katayose, K., Okamura, H., Kahn, C. R., Noda, T., Takeda, K., Akira, S., Inui, A., and Kasuga, M. (2006) Cell Metab. 3, 267-275
21. Todaro, G. J., and Green, H. (1963) J. Cell Biol. 17, 299-313
22. Mori, T., Sakaue, H., Iguchi, H., Gomi, H., Okada, Y., Takashima, Y., Nakamura, K., Nakamura, T., Yamauchi, T., Kubota, N., Kadowaki, T., Matsuki, Y., Ogawa, W., Hiramatsu, R., and Kasuga, M. (2005) J. Biol. Chem. 280, 12867-12875
23. Tamamori-Adachi, M., Hayashida, K., Nobori, K., Omizu, C., Yamada, K., Sakamoto, N., Kamura, T., Fukuda, K., Ogawa, S., Nakayama, K. I., and Kitajima, S. (2004) J. Biol. Chem. 279, 50429-50436
24. Seki, T., Irie, N., Nakamura, K., Sakaue, H., Ogawa, W., Kasuga, M., Yamamoto, H., Ohmori, S., Saito, N., and Sakai, N. (2006) Genes Cells 11, 1051-1070
25. Sakaue, H., Ogawa, W., Matsumoto, M., Kuroda, S., Takata, M., Sugimoto, T., Spiegelman, B. M., and Kasuga, M. (1998) J. Biol. Chem. 273, 28945-28952
26. Kitamura, T., Ogawa, W., Sakaue, H., Hino, Y., Kuroda, S., Takata, M., Matsumoto, M., Maeda, T., Konishi, H., Kikkawa, U., and Kasuga, M. (1998) Mol. Cell. Biol. 18, 3708-3717
27. Sakaue, H., Ogawa, W., Takata, M., Kuroda, S., Kotani, K., Matsumoto, M., Sakaue, M., Nishio, S., Ueno, H., and Kasuga, M. (1997) Mol. Endocrinol. 11, 1552-1562
28. Nourse, J., Firpo, E., Flanagan, W. M., Coats, S., Polyak, K., Lee, M. H., Massague, J., Crabtree, G. R., and Roberts, J. M. (1994) Nature 372, 570-573
29. Reynisdottir, I., Polyak, K., Iavarone, A., and Massague, J. (1995) Genes Dev. 9, 1831-1845
30. Kamura, T., Hara, T., Matsumoto, M., Ishida, N., Okumura, F., Hatakeyama, S., Yoshida, M., Nakayama, K., and Nakayama, K. I. (2004) Nat. Cell Biol. 6, 1229-1235
31. Weinberg, R. A. (1995) Cell 81, 323-330
32. Dyson, N. (1998) Genes Dev. 12, 2245-2262
33. Yu, B., Lane, M. E., Pestell, R. G., Albanese, C., and Wadler, S. (2000) Mol. Cell Biol. Res. Commun. 3, 352-359
34. Sherr, C. J., and Roberts, J. M. (1995) Genes Dev. 9, 1149-1163
35. Sherr, C. J., and Roberts, J. M. (1999) Genes Dev. 13, 1501-1512
36. Hengst, L., and Reed, S. I. (1998) Curr. Top. Microbiol. Immunol. 227, 25-41
37. Coats, S., Flanagan, W. M., Nourse, J., and Roberts, J. M. (1996) Science 272, 877-880
38. Slingerland, J., and Pagano, M. (2000) J. Cell. Physiol. 183, 10-17
39. Rodier, G., Montagnoli, A., Di Marcotullio, L., Coulombe, P., Draetta, G. F., Pagano, M., and Meloche, S. (2001) EMBO J. 20, 6672-6682
40. Boehm, M., Yoshimoto, T., Crook, M. F., Nallamshetty, S., True, A., Nabel, G. J., and Nabel, E. G. (2002) EMBO J. 21, 3390-3401
41. Shin, I., Yakes, F. M., Rojo, F., Shin, N. Y., Bakin, A. V., Baselga, J., and Arteaga, C. L. (2002) Nat. Med. 8, 1145-1152
42. Viglietto, G., Motti, M. L., Bruni, P., Melillo, R. M., D'Alessio, A., Califano, D., Vinci, F., Chiappetta, G., Tsichlis, P., Bellacosa, A., Fusco, A., and Santoro, M. (2002) Nat. Med. 8, 1136-1144
43. Liang, J., Zubovitz, J., Petrocelli, T., Kotchetkov, R., Connor, M. K., Han, K., Lee, J. H., Ciarallo, S., Catzavelos, C., Beniston, R., Franssen, E., and Slingerland, J. M. (2002) Nat. Med. 8, 1153-1160
44. Pedrali-Noy, G., Spadari, S., Miller-Faures, A., Miller, A. O., Kruppa, J., and Koch, G. (1980) Nucleic Acids Res. 8, 377-387
45. Zieve, G. M., Turnbull, D., Mullins, J. M., and McIntosh, J. R. (1980) Exp. Cell Res. 126, 397-405
46. Hashimoto, N., Kido, Y., Uchida, T., Asahara, S., Shigeyama, Y., Matsuda, T., Takada, A., Tsuchihashi, D., Nishizawa, A., Ogawa, W., Fujimoto, Y., Okamura, H., Arden, K. C., Herrera, P. L., Noda, T., and Kasuga, M. (2006) Nat. Genet. 38, 589-593
47. Koff, A., Giordano, A., Desai, D., Yamashita, K., Harper, W., Elledge, S., Nishimoto, T., Morgan, D., Franza, R., and Roberts, J. (1992) Science 257, 1689-1694
48. Obaya, A. J., and Sedivy, J. M. (2002) Cell. Mol. Life Sci. 59, 126-142
49. Novak, B., and Tyson, J. J. (2004) J. Theor. Biol. 230, 563-579
50. Pardee, A. B. (1989) Science 246, 603-608
51. Sherr, C. J. (1994) Cell 79, 551-555
52. Burgering, B. M., and Kops, G. J. (2002) Trends Biochem. Sci. 27, 352-360
53. Ramaswamy, S., Nakamura, N., Sansal, I., Bergeron, L., and Sellers, M. R. (2002) Cancer Cell 2, 81-91
54. Burgering, B. M., and Medema, R. H. (2003) J. Leukocyte Biol. 73, 689-701
55. Jiang, W., Kahn, S. M., Zhou, P., Zhang, Y. J., Cacace, A. M., Infante, A. S., Doi, S., Santella, R. M., and Weinstein, I. B. (1993) Oncogene 8, 3447-3457
56. Quelle, D. E., Ashmun, R. A., Shurtleff, S. A., Kato, J. Y., Bar-Sagi, D., Roussel, M. F., and Sherr, C. J. (1993) Oncogene 7, 1559-1571
57. Resnitzky, D., Gossen, M., Bujard, H., and Reed, S. I. (1994) Mol. Cell. Biol. 14, 1669-1679
58. Polyak, K., Lee, M. H., Erdjument-Bromage, H., Koff, A., Roberts, J. M., Tempst, P., and Massague, J. (1994) Cell 78, 59-66
59. Toyoshima, H., and Hunter, T. (1994) Cell 78, 67-74
60. Craig, C., Wersto, R., Kim, M., Ohri, E., Li, Z., Katayose, D., Lee, S. J., Trepel, J., Cowan, K., and Seth, P. (1997) Oncogene 14, 2283-2289
61. Uchida, T., Nakamura, T., Hashimoto, N., Matsuda, T., Kotani, K., Sakaue, H., Kido, Y., Hayashi, Y., Nakayama, K. I., White, M. F., and Kasuga, M. (2005) Nat. Med. 11, 175-182
62. Connor, M. K., Kotchetkov, R., Cariou, S., Resch, A., Lupetti, R., Beniston, R. G., Melchior, F., Hengst, L., and Slingerland, J. M. (2003) Mol. Biol. Cell 14, 201-213
63. Susaki, E., Nakayama, K., and Nakayama, K. I. (2007) Mol. Cell. Biol. 27, 4626-4640
64. Pagano, M., Tam, S. W., Theodoras, A. M., Beer-Romero, P., Del Sal, G., Chau, V., Yew, P. R., Draetta, G. F., and Rolfe, M. (1995) Science 269, 682-685
65. Malek, N. P., Sundberg, H., McGrew, S., Nakayama, K., Kyriakides, T. R., and Roberts, J. M. (2001) Nature 413, 323-327
66. Mamillapalli, R., Gavrilova, N., Mihaylova, V. T., Tsvetkov, L. M., Wu, H., Zhang, H., and Sun, H. (2001) Curr. Biol. 11, 263-267
67. Hopkin, K. (1998) Science 282, 1029-1030
68. Sun, H., Lesche, R., Li, D.-M., Liliental, J., Zhang, H., Gao, J., Gavrilova, N., Mueller, B., Liu, X., and Wu, H. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 6199-6204
69. Reichert, M., Saur, D., Hamacher, R., Schmid, R. M., and Schneider, G. (2007) Cancer Res. 67, 4149-4156
70. van Duijin, P. M., and Trapman, J. (2006) Prostate 66, 749-760
71. Shtivelman, E., Sussman, J., and Stokoe, D. (2002) Curr. Biol. 12, 919-924
72. Lee, S. R., Park, J. H., Park, E. K., Chung, C. H., Kang, S. S., and Bang, O. S. (2005) J. Cell. Physiol. 205, 270-277
73. Willard, F. S., and Crouch, M. F. (2001) Cell. Signal. 13, 653-664
74. Rodriguez-Viciana, P., Warne, P. H., Khwaja, A., Marte, B. M., Pappin, D., Das, P., Waterfield, M. D., Ridley, A., and Downward, J. (1997) Cell 89, 457-647