Embryonic striatal neurons from Niemann-Pick type C mice exhibit defects in cholesterol metabolism and neurotrophin responsiveness

Journal of Biological Chemistry

Volumn 275, Issue 26, 2000, Pages 20179-20187

  Henderson, Leslie P ^a   Lin, Li ^a   Prasad, Anita ^a   Paul, Colleen A ^a   Chang, Ta Yuan ^a   Maue, Robert A ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NEUROTROPHIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHOSPHORYLATION; BRAIN NERVE CELL; CELL SURFACE; CHOLESTEROL METABOLISM; CORPUS STRIATUM; EMBRYO; EMBRYO DEVELOPMENT; ESTERIFICATION; HYDROLYSIS; MOUSE; NERVE FIBER GROWTH; NIEMANN PICK DISEASE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BIOTINYLATION; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; CHOLESTEROL; CHOLESTEROL, LDL; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; GENOTYPE; GLUTAMATE DECARBOXYLASE; IMMUNOHISTOCHEMISTRY; MEMBRANE LIPIDS; MICE; MICE, MUTANT STRAINS; MUTATION; NERVE GROWTH FACTORS; NEURONS; NIEMANN-PICK DISEASES; PROTEINS; RECEPTOR, TRKB; SIGNAL TRANSDUCTION; SPHINGOLIPIDS;

ANIMALIA;

EID: 0034733750     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M001793200     Document Type: Article

References (75)

1. Pentchev, P. G., Vanier, M. T., Suzuki, K., and Patterson, M. C. (1995) in The Metabolic and Molecular Bases of Inherited Disease (Scriver, C. R., Stanbury, J. B., Wyngaarden, J. B., and Frederickson, D. S., eds) pp. 2625-2639, McGraw-Hill Inc., New York
2. Liscum, L., and Klansek, J. J. (1998) Curr. Opin. Lipidol. 9, 131-136
3. Morris, M. D., Bhuvaneswaran, C., Shio, H., and Fowler, S. (1982) Am. J. Pathol. 108, 140-149
4. Carstea, E. D., Morris, J. A., Coleman, K. G., Loftus, S. K., Zhang, D., Cummings, C., Gu, J., Rosenfeld, M. A., Pavan, W. J., Krizman, D. B., Nagle, J., Polymeropoulos, M. H., Sturley, S. L., Ioannou, Y. A., Higgins, M. E., Comly, M., Cooney, A., Brown, A., Kaneski, C. R., Blanchette-Mackie, E. J., Dwyer, N. K., Neufeld, E. B., Chang, T.-Y., Liscum, L., Strauss, J. F., III, Ohno, K., Zeigler, M., Carmi, R., Sokol, J., Markie, D., O'Neill, R. R., van Diggelen, O. P., Elleder, M., Patterson, M. C., Brady, R. O., Vanier, M. T., Pentchev, P. G., and Tagle, D. A. (1997) Science 277, 228-231
5. Loftus, S. K., Morris, J. A., Carstea, E. D., Gu, J. Z., Cummings, C., Brown, A., Ellison, J., Ohno, K., Rosenfeld, M. A., Tagle, D. A., Pentchev, P. G., and Pavan, W. J. (1997) Science 277, 232-235
6. Neufeld, E. B., Wastney, M., Patel, S., Suresh, S., Cooney, A. M., Dwyer, N. K., Roff, C. F., Ohno, K., Morris, J. A., Carstea, E. D., Incardona, J. P., Strauss, J. F., III, Vanier, M. T., Patterson, M. C., Brady, R. O., Pentchev, P. G., and Blanchette-Mackie, E. J. (1999) J. Biol. Chem. 274, 9627-9635
7. Cruz, J. C., Sugii, S., Yu, C., and Chang, T.-Y. (2000) J. Biol. Chem. 275, 4013-4021
8. Shio, H., Fowler, S., Bhuvaneswaran, C., and Morris, M. D. (1982) Am. J. Pathol. 108, 150-159
9. Weintraub, H., Abramovici, A., Sandbank, U., Pentchev, P. G., Brady, R. O., Sekine, M., Suzuki, A., and Sela, B. (1985) J. Neurochem. 45, 665-672
10. Fink, J. K., Filling-Katz, M. R., Sokol, J., Cogan, D. G., Pikus, A., Sonies, B., Soong, B., Pentchev, P. G., Comly, M. E., Brady, R. O., and Barton, N. W. (1989) Neurology 39, 1040-1049
11. March, P. A., Thrall, P. A., Brown, D. E., Mitchell, T. W., Lowenthal, A. C., and Walkley, S. U. (1997) Acta Neuropathol. 94, 164-172
12. Love, S., Bridges, L. R., and Case, P. (1995) Brain 118, 119-129
13. Suzuki, K., Parker, C. C., Pentchev, P. G., Katz, D., Ghetti, B., D'Agostino, A. N., and Carstea, E. D. (1995) Acta Neuropathol. 89, 227-238
14. Ventimiglia, R., Mather, P., Jones, B. E., and Lindsay, R. M. (1995) Eur. J. Neurosci. 7, 213-222
15. Ikeda, Y., Nishiyama, N., Saito, H., and Katsuki, H. (1997) Dev. Brain Res. 98, 253-258
16. Gerfen, C. R. (1992) Annu. Rev. Neurosci. 15, 285-320
17. Kawaguchi, Y., Wilson, C. J., Augood, S. J., and Emson, P. C. (1995) Trends Neurosci. 18, 527-535
18. Mizuno, K., Carnahan, J., and Nawa, H. (1994) Dev. Biol. 165, 243-256
19. Merlio, J. P., Ernfors, P., Jaber, M., and Persson, H. (1992) Neuroscience 51, 513-532
20. Ernfors, P., Merlio, J.-P., and Persson, H. (1992) Eur. J. Neurosci. 4, 1140-1158
21. Ernfors, P., Rosario, C. M., Merlio, J. P., Grant, G., Aldskogius, H., and Persson, H. (1993) Mol. Brain Res. 17, 217-226
22. Simons, K., and Ikonen, E. (1997) Nature 397, 569-572
23. Hooper, N. M. (1999) Mol. Membr. Biol. 16, 145-156
24. Bottenstein, J., Hayashi, I., Hutching, S., Masui, H., Mather, J., McClure, D. B., Ohasa, S., Rizzino, A., Sato, G., and Serrero, G. (1979) Methods Enzymol. 58, 94-109
25. Cadigan, K. M., Heider, J. G., and Chang, T. Y. (1988) J. Biol. Chem. 263, 274-282
26. Chang, C. C. Y., Doolittle, G. M., and Chang, T. Y. (1986) Biochemistry 25, 1693-1699
27. Heider, J. G., and Boyett, R. L. (1978) J. Lipid Res. 19, 514-518
28. Kagawa, Y., and Racker, E. (1966) J. Biol. Chem. 241, 2461-2466
29. Roberts, D. C. K., Miller, N. E., and Price, S. G. L. (1985) Biochem. J. 226, 319-322
30. Cadigan, K. M., Spillane, D. M., and Chang, T. Y. (1990) J. Cell Biol. 110, 295-308
31. de la Torre, J. R., Hopker, V. H., Ming, G., Poo, M.-M., Tessier-Lavigne, M., Hemmati-Brivanlou, A., and Holt, C. E. (1997) Neuron 19, 1211-1224
32. Suh, N., Wang, Y., Honda, T., Gribble, G. W., Dmitrovsky, E., Hickey, W. F., Maue, R. A., Place, A. E., Porter, D. M., Spinella, M. J., Williams, C. R., Wu, G., Dannenberg, A. J., Flanders, K. C., Letterio, J. J., Mangelsdorf, D. J., Nathan, C. F., Nguyen, L., Porter, W. W., Ren, R. F., Roberts, A. B., Roche, N. S., Subbaramaiah, K., and Sporn, M. B. (1999) Cancer Res. 59, 336-341
33. Simons, M., Keller, P., DeStrooper, B., Beyreuther, K., Dotti, C. G., and Simons, K. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6460-6464
34. Ledesma, M. D., Simons, K., and Dotti, C. G. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 3966-3971
35. Xie, C., Turley, S., Pentchev, P. G., and Dietschy, J. M. (1999) Am. J. Physiol. 276, E336-E344
36. Patel, S. C., Suresh, S., Weintraub, H., Brady, R. O., and Pentchev, P. G. (1987) Biophys. Res. Commun. 143, 233-240
37. Goldin, E., Roff, C. F., Miller, S. P. F., Rodriquez-Lafrasse, C., Vanier, M. T., Brady, H. O., and Pentchev, P. G. (1992) Biochim. Biophys. Acta 1127, 303-311
38. Tint, G. S., Pentchev, P., Xu, G., Batta, A. K., Shefer, S., Salen, G., and Honda, A. (1998) J. Inherited Metab. Dis. 21, 853-863
39. Xie, C., Turley, S. D., and Dietschy, J. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 11992-11997
40. Handelmann, G. E., Boyles, J. K., Weisgraber, K. H., Mahley, R. W., and Pitas, R. E. (1992) J. Lipid Res. 33, 1677-1688
41. de Chaves, E. I., Rusinol, A. E., Vance, D. E., Campenot, R. B., and Vance, J. E. (1997) J. Biol. Chem. 272, 30766-30773
42. Masserini, M., Palestrini, P., and Pitto, M. (1999) J. Neurochem. 73, 1-11
43. Wu, C., Butz, S., Ying, Y., and Anderson, R. G. W. (1997) J. Biol. Chem. 272, 3554-3559
44. Kaplan, D. R., and Stephens, R. M. (1994) J. Neurobiol. 25, 1404-1417
45. Hartman, D. S., and Hertel, C. (1994) J. Neurochem. 63, 1261-1270
46. Bilderback, T. R., Valeswara-Rao, G., Lisanti, M. P., and Dobrowsky, R. T. (1999) J. Biol. Chem. 274, 257-263
47. Lamballe, F., Klein, R., and Barbacid, M. (1991) Cell 66, 967-979
48. Ip, N. Y., Li, Y., Yancopoulos, G. D., and Lindsay, R. M. (1993) J. Neurosci. 13, 3394-3405
49. Knusel, B., Gao, H., Okazaki, T., Yoshida, T., Mon, N., Hefti, F., and Kaplan, D. R. (1997) Neuroscience 78, 851-862
50. Escandon, E., Soppet, D., Rosenthal, A., Mendoza-Ramirez, J. L., Szonyi, E., Burton, L. E., Henderson, C. E., Parada, L. F., and Nikolics, K. (1994) J. Neurosci. 14, 2054-2068
51. Meyer-Franke, A., Wilkinson, G. A., Kruttgen, A., Hu, M., Munro, E., Hanson, M. G., Reichardt, L. F., and Barres, B. A. (1998) Neuron 21, 681-693
52. Turley, S. D., and Dietschy, J. M. (1997) Nutr. Metab. Cardiovasc. Dis. 7, 195-201
53. Turley, S. D., Burns, D. K., Rosenfeld, C. R., and Dietschy, J. M. (1996) J. Lipid Res. 37, 1953-1961
54. Jurevics, H. A., Kidwai, F. Z., and Morell, P. (1997) J. Lipid Res. 38, 723-733
55. Pitas, R. E., Boyles, J. K., Lee, S. H., Foss, D., and Mahley, R. W. (1987) Biochim. Biophys. Acta 917, 148-161
56. Weisgraber, K. H., Roses, A. D., and Strittmatter, W. J. (1994) Curr. Opin. Lipidol. 5, 110-116
57. Narita, M., Bu, G., Holtzman, D. M., and Schwartz, A. L. (1997) J. Neurochem. 68, 587-595
58. Trommsdorff, M., Gotthardt, M., Hiesberger, T., Shelton, J., Stockinger, W., Nimpf, J., Hammer, R. E., Richardson, J. A., and Herz, J. (1999) Cell 97, 689-701
59. Chao, M. V. (1995) Mol. Cell. Neurosci. 6, 91-96
60. Hancock, J. F., Magee, A. I., Childs, J. E., and Marshall, C. J. (1989) Cell 57, 1167-1177
61. Roy, S., Luetterforst, R., Harding, A., Apolloni, A., Etheridge, M., Stang, E., Rolls, B., Hancock, J. F., and Parton, R. G. (1999)Nat. Cell Biol. 1, 98-105
62. Weis, F. M. B., and Davis, R. J. (1990) J. Biol. Chem. 266, 12059-12066
63. Mutoh, T., Tkuda, A., Miyadai, T., Hamaguchi, M., and Fujiki, N. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5087-5091
64. Rabin, S. J., and Mocchetti, I. (1995) J. Neurochem. 65, 347-354
65. Yates, A. J., Saqr, H. E., and Van Brocklyn, J, (1995) J. Neuro-oncol. 24, 65-73
66. Garver, W. S., Erickson, R. P., Wilson, J. M., Colton, T. L., Hossain, G. S., Kozloski, M. A., and Heidenreich, R. A. (1997) Biochim. Biophys. Acta 1361, 272-280
67. Liu, P., Oh, P., Horner, T., Rogers, R. A., and Schnitzer, J. E. (1997) J. Biol. Chem. 272, 7211-7222
68. Furuchi, T., and Anderson, R. G. W. (1998) J. Biol. Chem. 273, 21099-21104
69. Murata, M., Peranen, J., Schreiner, R., Wieland, F., Kurzchalia, T. V., and Simons, K. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 10339-10343
70. Fielding, C. J., and Fielding, P. E. (1997) J. Lipid Res. 38, 1503-1521
71. Gao, W.-Q., Zheng, J. L., and Karihaloo, M. (1995) J. Neurosci. 15, 2656-2667
72. Patterson, S. L., Abel, T., Deuel, T. A., Martin, K. C., Rose, J. C., and Kandel, E. R. (1996) Neuron 16, 1137-1145
73. Snider, W. D. (1994) Cell 77, 627-638
74. McAllister, K. A., Katz, L. C., and Lo, D. C. (1999) Annu. Rev. Neurosci. 22, 295-318
75. Minichiello, L., Korte, M., Wolfer, D., Kühn, R., Unsicker, K., Cestari, V., Rossi-Arnaud, C., Lipp, H.-P., Bonhoeffer, T., and Klein, R. (1999) Neuron 24, 401-414