EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains

Neuron

Volumn 22, Issue 3, 1999, Pages 511-524

  Brückner, Katja ^a   Labrador, Juan Pablo ^a   Scheiffele, Peter ^b,c   Herb, Anne ^d   Seeburg, Peter H ^d   Klein, Rüdiger ^a  

^a Developmental Biology Programme   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CHOLESTEROL; EPHRIN B; GLUTAMATE RECEPTOR INTERACTING PROTEIN; LIGAND; PDZ ADAPTOR PROTEIN; PROTEIN TYROSINE KINASE; SPHINGOLIPID; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RAT; SIGNAL TRANSDUCTION;

EID: 0033103887     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80706-0     Document Type: Article

References (54)

1. Adams, R.H., Wilkinson, G.A., Weiss, C., Diella, F., Gale, N.W., Deutsch, U., Risau, W., and Klein, R. (1999). Roles of ephrinB ligands and EphB receptors in cardiovascular development: Demarcation of arterial/venous domains, vascular morphogenesis and sprouting angiogenesis. Genes Dev, 13, 295-306.
2. Allison, D.W., Gelfand, V.I., Spector, I., and Craig, A.M. (1998). Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: Differential attachment of NMDA versus AMPA receptors. J. Neurosci. 18, 2423-2436.
3. Bartel, P.L., Chien, C.-T., Sternglanz, R., and Fields, S. (1993). Using the two-hybrid system to detect protein-protein interactions. In Cellular Interactions in Development: A Practical Approach, D.A. Hartley, ed. (Oxford: Oxford University Press), 153-179.
4. Bergemann, A.D., Zhang, L., Chiang, M.K., Brambilla, R., Klein, R., and Flanagan, J.G. (1998). Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube. Oncogene 16, 471-480.
5. Bredt, D.S. (1998). Sorting out genes that regulate epithelial and neuronal polarity. Cell 94, 691-694.
6. Brown, D. (1993). The tyrosine kinase connection: How GPI-anchored proteins activate T cells. Curr. Opin. Immunol. 5, 349-354.
7. Brown, D., and London, E. (1998). Functions of lipid rafts in biological membranes. Annu. Rev. Cell Dev. Biol. 14, 111-136.
8. Brown, D.A., and Rose, J.K. (1992). Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell 68, 533-544.
9. Brückner, K., and Klein, R. (1998). Signalling by Eph receptors and their ephrin ligands. Curr. Opin. Neurobiol. 8, 375-382.
10. Brückner, K., Pasquale, E.B., and Klein, R. (1997). Tyrosine phosphorylation of transmembrane ligands for Eph receptors. Science 275, 1640-1643.
11. + channel Kir 2.3 to PSD-95 is regulated by protein kinase A phosphorylation. Neuron 17, 759-767.
12. Craven, S.E., and Bredt, D.S. (1998). PDZ proteins organize synaptic signaling pathways. Cell 93, 495-498.
13. Davis, S., Gale, N.W., Aldrich, T.H., Maisonpierre, P.C., Lhotak, V., Pawson, T., Goldfarb, M., and Yancopoulos, G.D. (1994). Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity. Science 266, 816-819.
14. Dong, H., O'Brien, R.J., Fung, E.T., Lanahan, A.A., Worley, P.F., and Huganir, R.L. (1997). GRIP: A synaptic PDZ domain-containing protein that interacts with AMPA receptors. Nature 386, 279-284.
15. Durbin, L., Brennan, C., Shiomi, K., Cooke, J., Barrios, A., Shanmugalingam, S., Guthrie, B., Lindberg, R., and Holder, N. (1998). Eph signaling is required for segmentation and differentiation of the somites. Genes Dev. 12, 3096-3109.
16. Flanagan, J.G., and Vanderhaeghen, P. (1998). The ephrins and Eph receptors in neural development. Annu. Rev. Neurosci. 21, 309-345.
17. Frangioni, J.V., and Neel, B.G. (1993). Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins. Anal. Biochem. 210, 179-187.
18. Friedrichson, T., and Kurzchalia, T.V. (1998). Microdomains of GPI-anchored proteins in living cells revealed by crosslinking. Nature 394, 802-805.
19. Gale, N.W., Flenniken, A., Compton, D.C., Jenkins, N., Copeland, N.G., Gilbert, D.J., Davis, S., Wilkinson, D., and Yancopoulos, G.D. (1996). Elk-L3, a novel transmembrane ligand for the Eph family of receptor tyrosine kinases. Oncogene 13, 1343-1352.
20. Gietz, D., St. Jean, A., Woods, R.A., and Schiestl, R.H. (1992). Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20, 1425.
21. Harder, T., Scheiffele, P., Verkade, P., and Simons, K. (1998). Lipid domain structure of the plasma membrane revealed by patching of membrane components. J. Cell Biol. 141, 929-942.
22. Henkemeyer, M., Orioli, D., Henderson, J.T., Saxton, T.M., Roder, J., Pawson, T., and Klein, R. (1996). Nuk controls pathfinding of commissural axons in the mammalian central nervous system. Cell 86, 35-46.
23. Hoffman, C.S., and Winston, F. (1987). A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. Gene 57, 267-272.
24. Holland, S.J., Gale, N.W., Mbamalu, G., Yancopoulos, G.D., Henkemeyer, M., and Pawson, T. (1996). Bidirectional signaling through the EPH-family receptor Nuk and its transmembrane ligands. Nature 383, 722-725.
25. Holland, S.J., Peles, E., Pawson, T., and Schlessinger, J. (1998). Cell-contact-dependent signaling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatases β. Curr. Opin. Neurobiol. 8, 117-127.
26. Holowka, D., and Baird, B. (1996). Antigen-mediated IgE receptor aggregation and signaling: A window on cell surface structure and dynamics. Annu. Rev. Biophys. Biomol. Struct. 25, 79-112.
27. Kamps, M. (1991). Determination of phosphoamino acid composition by acid hydrolysis of protein blotted to immobilon. Methods Enzymol. 201, 21-27.
28. Kikkawa, U., Takai, Y., Tanaka, Y., Miyake, R., and Nishizuka, Y. (1983). Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters. J. Biol. Chem. 258, 11442-11445.
29. Kim, S.K. (1997). Polarized signaling: Basolateral receptor localization in epithelial cells by PDZ-containing proteins. Curr. Opin. Cell Biol. 9, 853-859.
30. Kornau, H.-C., Schenker, L.T., Kennedy, M.B., and Seeburg, P.H. (1995). Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 269, 1737-1740.
31. Kornau, H.-C., Seeburg, P.M., and Kennedy, M.B. (1997). Interactions of ion channels and receptors with PDZ domain proteins. Curr. Opin. Neurobiol. 7, 368-373.
32. Labrador, J.P., Brambilla, R., and Klein, R. (1997). The amino-terminal globular domain of Eph receptors is sufficient for ligand binding and receptor signaling. EMBO J. 16, 3889-3897.
33. Montixi, C., Langlet, C., Bernard, A.-M., Thimonier, J., Dubois, C., Wurbel, M.-A., Chauvin, J.-P., Pierres, M., and He, H.-T. (1998). Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains. EMBO J. 17, 5334-5348.
34. Orioli, D., and Klein, R. (1997). The Eph receptor family: Axonal guidance by contact repulsion. Trends Genet. 13, 354-359.
35. Pawson, T., and Scott, J.D. (1997). Signaling through scaffold, anchoring, and adaptor proteins. Science 278, 2075-2080.
36. Ponting, C.P., Phillips, C., Davies, K.E., and Blake, D.J. (1997). PDZ domains: Targeting signaling molecules to sub-membranous sites. Bioessays 19, 469-479.
37. Ranganathan, R., and Ross, E.M. (1997). PDZ domain proteins: Scaffolds for signaling complexes. Curr. Biol. 7, R770-R773.
38. Scheiffele, P., Roth, M.G., and Simons, K. (1997). Interaction of influenza virus haemagglutinin sphingolipid-cholesterol membrane domains via its transmembrane domain. EMBO J. 16, 5501-5508.
39. Sheng, M. (1996). PDZs and receptor/channel clustering: Rounding up the latest suspects. Neuron 17, 575-578.
40. Simons, K., and Ikonen, E. (1997). Functional rafts in cell membranes. Nature 387, 569-572.
41. Songyang, Z., Fanning, A.S., Fu, C., Xu, J., Marfatia, S.M., Chishti, A.H., Crompton, A., Chan, A.C., Anderson, J.M., and Cantley, L.C. (1997). Recognition of unique carboxyl-terminal motifs by distinct PDZ domains. Science 275, 73-77.
42. Srivastava, S., Osten, P., Vilim, F.S., Khatri, L., Inman, G., States, B., Daly, C., DeSouza, S., Abagyan, R., Valtschanoff, J.G., et al. (1998). Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP. Neuron 21, 581-591.
43. Staudinger, J., Zhou, J., Burgess, R., Elledge, S.J., and Olson, E.N. (1995). PICK1: A perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system. J. Cell Biol. 128, 263-271.
44. Staudinger, J., Lu, J., and Olson, E.N. (1997). Specific interaction of the PDZ domain protein PICK1 with the COOH terminus of protein kinase C-alpha. J. Biol. Chem. 272, 32019-32024.
45. Stauffer, T.P., and Meyer, T. (1997). Compartmentalized IgE receptor-mediated signal transduction in living cells. J. Cell Biol. 139, 1447-1454.
46. Stein, E., Lane, A.A., Cerretti, D.P., Schoecklmann, H.O., Schroff, A.D., Van Etten, R.L., and Daniel, T.O. (1998). Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses. Genes Dev. 12, 667-678.
47. Torres, R., Firestein, B.L., Dong, H., Staudinger, J., Olson, E.N., Huganir, R.L., Bredt, D.S., Gale, N.W., and Yancopoulos, G.D. (1998). PDZ proteins bind, cluster and synaptically colocalize with Eph receptors and their ephrin ligands. Neuron, 21, 1453-1463.
48. Tsunoda, S., Sierralta, J., Sun, Y., Bodner, R., Suzuki, E., Backer, A., Socolich, M., and Zuker, C.S. (1997). A multivalent PDZ-domain protein assembles signaling complexes in a G-protein-coupled cascade. Nature 388, 243-249.
49. 2+-signaling competent. J. Cell Biol. 131, 669-677.
50. Varma, R., and Mayor, S. (1998). GPI-anchored proteins are organized in submicron domains at the cell surface. Nature 394, 798-801.
51. Wang, H.U., Chen, Z.-F., and Anderson, D.J. (1998). Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93, 741-753.
52. 35S-labelled oligonucleotide probes. In In Situ Hybridization Protocols for the Brain, W. Wisden and B.J. Morris, eds. (Oxford: Academic Press), 9-34.
53. Xavier, R., Brennan, T., Li, Q., McCormack, C., and Seed, B. (1998). Membrane compartmentation is required for efficient T cell activation. Immunity 8, 723-732.
54. Yancopoulos, G.D., Klagsbrun, M., and Folkman, J. (1998). Vasculogenesis, angiogenesis, and growth factors: Ephrins enter the fray at the border. Cell 93, 661-664.