Recent advances in antiviral activity of benzo/heterothiadiazine dioxide derivatives

Current Medicinal Chemistry

Volumn 15, Issue 15, 2008, Pages 1529-1540

  Zhan, Peng ^a   Liu, Xinyong ^a   De Clercq, Erik ^b  

^a SHANDONG UNIVERSITY   (China)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Antiviral; Benzothiadiazine; HCMV; HCV; Heterocyclic compound; Heterothiadiazine; HIV; Thiadiazine; VZV

Indexed keywords

1 (2 CYCLOPROPYLETHYL) 3 (1,1 DIOXO 2H 1,2,4 BENZOTHIADIAZIN 3 YL) 6 FLUORO 4 HYDROXY 2(1H)QUINOLINONE; 1 [(2 ACETOXYETHOXY)METHYL] 4 AMINO 6 BENZYL(5H)IMIDAZO[4,5 C] 1,2,6 THIADIAZINE 2,2 DIOXIDE; 1 BUTYL 3 (1,1 DIOXIDO 2H 1,2,4 BENZOTHIADIAZIN 3 YL) 4 HYDROXY 2(1H)QUINOLINONE; 2 (3 CHLOROBENZYL) 4 CYANOMETHYLEN 1,1,3 TRIOXO 2H,4H THIENOL[3,4 E][1,2,4]THIADIAZINE; 2 (3 FLUOROBENZYL) 4 CYANOMETHYL 2H,4H THIENO[3,4 E][1,24]THIADAZINE; 2 (3 FLUOROBENZYL) 4 CYANOMETHYLENE 1,1,3 TRIOXO 2H,4H THIENO[3,4 E][1,2,4]THIADIAZINE; 2 BENZYL 4 (2 CHLOROBENZYL) 2H,4H THIENO[3,4 E][1,2,4]THIADIAZINE; 2 BENZYL 4 CYANOMETHYL 1,1,3 TRIOXO 2H,4H THIENOL[3,4 E][1,2,4]THIADIAZINE; 2 BENZYL 4 CYANOMETHYLENE 1,1,3 TRIOXO 2H,4H THIENO[3,4 E][1,2,4]THIADIAZINE; 3 (1,1 DIOXO 2H 1,2,4 BENZOTHIADIAZIN 3 YL) 4 HYDROXY 2(1H)QUINOLINONE; 5 HYDROXY 3(2H)PYRIDAZINONE DERIVATIVE; A 782759; ACICLOVIR; ALPHA INTERFERON; ANTIRETROVIRUS AGENT; ANTIVIRUS AGENT; BENZOTHIADIAZINE DIOXIDE DERIVATIVE; BENZOTHIENOTHIADIAZINE DERIVATIVE; CHLOROBENZYL BENZOTHIADIAZINE DIOXIDE DERIVATIVE; EFAVIRENZ; GANCICLOVIR; HETEROTHIADIAZINE DIOXIDE DERIVATIVE; IMIDAZOTHIADIAZINE DIOXIDE DERIVATIVE; NEVIRAPINE; NSC 287474; PEGINTERFERON ALPHA; QM 96539; QM 96625; RIBAVIRIN; RNA DIRECTED DNA POLYMERASE INHIBITOR; THIADIAZINE DERIVATIVE; THIENOTHIADIAZINE DERIVATIVE; UNINDEXED DRUG; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ANTIVIRAL RESISTANCE; CHICKENPOX; COMPARATIVE MOLECULAR FIELD ANALYSIS; CYTOMEGALOVIRUS INFECTION; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SAFETY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; HEPATITIS C; HEPATITIS C VIRUS; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CYTOMEGALOVIRUS; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYDROGEN BOND; IC 50; NONHUMAN; REVIEW; STRUCTURE ACTIVITY RELATION; UNSPECIFIED SIDE EFFECT; VARICELLA ZOSTER VIRUS; VIRUS INHIBITION; VIRUS REPLICATION; X RAY CRYSTALLOGRAPHY;

ANTIVIRAL AGENTS; BENZOTHIADIAZINES; HUMANS; OXIDES; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUSES;

EID: 47349087833     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986708784638898     Document Type: Review

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