Benzothiadiazine dioxides (BTD) derivatives as non-nucleoside human cytomegalovirus (HCMV) inhibitors. Study of structural requirements for biological activity

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 11, 2003, Pages 2395-2402

  Martinez, Ana ^a   Gil, Carmen ^a   Castro, Ana ^a   Pérez, Concepción ^a   Prieto, Columbiana ^b   Otero, Joaquin ^b  

^a INSTITUTO DE QUÍMICA MÉDICA   (Spain)

^b HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

1 (PHENYLBUTYL) 3 BENZYL 2,1,3 BENZOTHIADIAZIN 4 ONE 2,2 DIOXIDE; 1 [(3,4 DICHLOROPHENYL)METHYL] 3 BENZYL 2,1,3 BENZOTHIADIAZINE 2,2 DIOXIDE; 1 [(3,4 DICHLOROPHENYL)METHYL] 3 ETHYL 2,1,3 BENZOTHIADIAZIN 4 ONE 2,2 DIOXIDE; 1 [(3,4 DICHLOROPHENYL)METHYL] 3 ISOBUTYL 2,1,3 BENZOTHIADIAZIN 4 ONE 2,2 DIOXIDE; 1 [(3,4 DICHLOROPHENYL)METHYL] 4 (CYCLOHEXYLMETHYLOXY) 2,1,3 BENZOTHIADIAZINE 2,2 DIOXIDE; 1 [(3,4 DICHLOROPHENYL)METHYL] 4 (ISOBUTYLOXY) 2,1,3 BENZOTHIADIAZINE 2,2 DIOXIDE; 1 [(3,4 DICHLOROPHENYL)METHYL] 4 (ISOPROPYLOXY) 2,1,3 BENZOTHIADIAZINE 2,2 DIOXIDE; 1 [(4 BROMOPHENYL)CARBONYLMETHYL] 3 BENZYL 2,1,3 BENZOTHIADIAZIN 4 ONE 2,2 DIOXIDE; 1 [(4 CHLOROPHENYL)METHYL] 3 CYCLOHEXYLMETHYL 2,1,3 BENZOTHIADIAZIN 4 ONE 2,2 DIOXIDE; 1 [(4 CHLOROPHENYL)METHYL] 3 ETHYL 2,1,3 BENZOTHIADIAZIN 4 ONE 2,2 DIOXIDE; 1 [(4 CHLOROPHENYL)METHYL] 3 ISOBUTYL 2,1,3 BENZOTHIADIAZIN 4 ONE 2,2 DIOXIDE; 1 [(4 CHLOROPHENYL)METHYL] 3 ISOPROPYL 2,1,3 BENZOTHIADIAZIN 4 ONE 2,2 DIOXIDE; 1 [(4 CHLOROPHENYL)METHYL] 3 METHYL 2,1,3 BENZOTHIADIAZIN 4 ONE 2,2 DIOXIDE; 1 [(4 CHLOROPHENYL)METHYL] 3 PROPARGYL 2,1,3 BENZOTHIADIAZIN 4 ONE 2,2 DIOXIDE; 1 [(4 CHLOROPHENYL)METHYL] 3 PROPYL 2,1,3 BENZOTHIADIAZIN 4 ONE 2,2 DIOXIDE; 1 [(4 CHLOROPHENYL)METHYL] 4 (CYCLOHEXYLMETHYLOXY) 2,1,3 BENZOTHIADIAZIN 4 ONE 2,2 DIOXIDE; 1 [(4 CHLOROPHENYL)METHYL] 4 (ETHYLOXY) 2,1,3 BENZOTHIADIAZINE 2,2 DIOXIDE; 1 [(4 CHLOROPHENYL)METHYL] 4 (ISOBUTYLOXY) 2,1,3 BENZOTHIADIAZINE 2,2 DIOXIDE; 1 [(4 CHLOROPHENYL)METHYL] 4 (ISOPROPYLOXY) 2,1,3 BENZOTHIADIAZINE 2,2 DIOXIDE; 1 [(4 CHLOROPHENYL)METHYL] 4 (METHYLOXY) 2,1,3 BENZOTHIADIAZINE 2,2 DIOXIDE; 1 [(4 CHLOROPHENYL)METHYL] 4 (PROPYLOXY) 2,1,3 BENZOTHIADIAZINE 2,2 DIOXIDE; ANTIVIRUS AGENT; BENZOTHIADIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HOST CELL; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; IC 50; STRUCTURE ACTIVITY RELATION;

HUMAN HERPESVIRUS 5;

EID: 0037624825     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(03)00148-2     Document Type: Article

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