Resistance Profile of a Hepatitis C Virus RNA-Dependent RNA Polymerase Benzothiadiazine Inhibitor

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 11, 2003, Pages 3525-3530

  Nguyen, Tammy T ^a   Gates, Adam T ^a   Gutshall, Lester L ^a   Johnston, Victor K ^a   Gu, Baohua ^a   Duffy, Kevin J ^a   Sarisky, Robert T ^a,b  

^a GLAXOSMITHKLINE   (United States)

^b CENTOCOR INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BENZO 1,2,4 THIADIAZINE; BENZOTHIADIAZINE DERIVATIVE; ENZYME INHIBITOR; METHIONINE; RNA DIRECTED RNA POLYMERASE; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG SENSITIVITY; DRUG SPECIFICITY; ENZYME INHIBITION; GENETIC CODE; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; MOLECULAR CLONING; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; REPLICON; SPONTANEOUS MUTATION;

BENZOTHIADIAZINES; CELL LINE; DNA, COMPLEMENTARY; DRUG RESISTANCE, VIRAL; ENZYME INHIBITORS; HEPACIVIRUS; HUMANS; MUTAGENESIS, SITE-DIRECTED; REPLICON; RNA REPLICASE; RNA, VIRAL; VIRAL PROTEINS;

EID: 0242290994     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.11.3525-3530.2003     Document Type: Article

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