Novel 1,1,3-trioxo-2H,4H-thieno [3,4-e] [1,2,4] thiadiazine derivatives as non-nucleoside reverse transcriptase inhibitors that inhibit human immunodeficiency virus type 1 replication

Journal of Medicinal Chemistry

Volumn 41, Issue 21, 1998, Pages 4109-4117

  Arranz, Esther ^a   Díaz, Juan A ^a   Ingate, Simon T ^a   Witvrouw, Myriam ^b   Pannecouque, Christophe ^b   Balzarini, Jan ^b   De Clercq, Erik ^b   Vega, Salvador ^a  

^a INSTITUTO DE QUÍMICA MÉDICA   (Spain)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

1,1,3 TRIOXO 2H,4H THIENO[3,4 E][1,2,4]THIADIAZINE DERIVATIVE; 2 BENZYL 4 (2 CHLOROBENZYL) 1,1,3 TRIOXO 2H,4H THIENO[3,4 E][1,2,4]THIADIAZINE; 2 BENZYL 4 CYANOMETHYL 2H,4H THIENO[3,4 E][1,2,4]THIADIAZINE; 2 BENZYL 4 CYANOMETHYLENE 1,1,3 TRIOXO 2H,4H THIENO[3,4 E][1,2,4]THIADIAZINE; ANTIVIRUS AGENT; NEVIRAPINE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; VIRUS INHIBITION; VIRUS REPLICATION;

CELL LINE; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZINES; VIRUS REPLICATION;

EID: 0032497648     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9802012     Document Type: Article

References (17)

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