Glycosyltransferases, important tools for drug design

Current Topics in Medicinal Chemistry

Volumn 8, Issue 8, 2008, Pages 680-709

  Luzhetskyy, Andriy ^a   Méndez, Carmen ^b   Salas, Jose A ^b   Bechthold, Andreas ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

Author keywords

Anthracyclines; Bleomycins; Chemotherapy; Glycosylated Natural Products; Macrolide antibiotics; Spinosyns

Indexed keywords

ACARBOSE; ACLARUBICIN; AMINOCOUMARIN DERIVATIVE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMPHOTERICIN B; AVERMECTIN; AVILAMYCIN; BLEOMYCIN DERIVATIVE; CHARTREUSIN; DAUNORUBICIN; DIGOXIN; DOXORUBICIN; ENEDIYNE; ERYTHROMYCIN; GLYCOSYLTRANSFERASE; GRANATICIN; MEGALOMICIN; METHYMYCIN; NATAMYCIN; NOGALAMYCIN; NYSTATIN; OLEANDOMYCIN; POLYENE ANTIBIOTIC AGENT; POLYPEPTIDE ANTIBIOTIC AGENT; REBECCAMYCIN; TEICOPLANIN; TERPENE DERIVATIVE; UNINDEXED DRUG; VANCOMYCIN; VICENISTATIN;

ACTINOBACTERIA; ANTINEOPLASTIC ACTIVITY; BACTERIAL STRAIN; CARBOHYDRATE ANALYSIS; CATALYSIS; CHEMICAL MODIFICATION; CLINICAL TRIAL; COMBINATORIAL CHEMISTRY; DIABETES MELLITUS; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME MODIFICATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; GLYCOSYLATION; HEART FAILURE; HUMAN; IN VITRO STUDY; INFECTION; METABOLIC ENGINEERING; NEOPLASM; NONHUMAN; PARASITOSIS; REVIEW; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; BIOLOGICAL PRODUCTS; CATALYSIS; DRUG DESIGN; GLYCOSYLTRANSFERASES; HUMANS; MACROLIDES;

EID: 47149087571     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802608784221514     Document Type: Review

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