메뉴 건너뛰기




Volumn 15, Issue 3, 2008, Pages 101-112

The role of sphingosine kinase and sphingosine-1-phosphate in the regulation of endothelial cell biology

Author keywords

Angiogenesis; Endothelial Cells; Inflammation; Sphingosine Kinase; Sphingosine 1 Phosphate

Indexed keywords

5 (4 PHENYL 5 TRIFLUOROMETHYL 2 THIENYL) 3 (3 TRIFLUOROMETHYLPHENYL) 1,2,4 OXADIAZOLE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FIBROBLAST GROWTH FACTOR; HIGH DENSITY LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; SPHINGOMYELIN; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE KINASE; SPHINGOSINE KINASE 1; SPHINGOSINE KINASE 2; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; VASCULAR CELL ADHESION MOLECULE 1;

EID: 45949102390     PISSN: 10623329     EISSN: 10292373     Source Type: Journal    
DOI: 10.1080/10623320802125342     Document Type: Short Survey
Times cited : (27)

References (140)
  • 2
    • 33644886904 scopus 로고    scopus 로고
    • High expression of sphingosine kinase 1 and S1P receptors in chemotherapy-resistant prostate cancer PC3 cells and their camptothecin-induced upregulation
    • Akao, Y., Banno, Y., Nakagawa, Y., Hasegawa, N., Kim, T. J., Murate, T., Igarashi, Y. and Nozawa, Y. (2006) High expression of sphingosine kinase 1 and S1P receptors in chemotherapy-resistant prostate cancer PC3 cells and their camptothecin-induced upregulation. Biochemical and Biophysical Research Communications, 342, pp. 1284-1290.
    • (2006) Biochemical and Biophysical Research Communications , vol.342 , pp. 1284-1290
    • Akao, Y.1    Banno, Y.2    Nakagawa, Y.3    Hasegawa, N.4    Kim, T.J.5    Murate, T.6    Igarashi, Y.7    Nozawa, Y.8
  • 4
    • 8844254137 scopus 로고    scopus 로고
    • Cardiovascular effects of sphingosine-1-phosphate and other sphingomyelin metabolites
    • Alewijnse, A. E., Peters, S. L. and Michel, M. C. (2004) Cardiovascular effects of sphingosine-1-phosphate and other sphingomyelin metabolites. British Journal of Pharmacology, 143, pp. 666-684.
    • (2004) British Journal of Pharmacology , vol.143 , pp. 666-684
    • Alewijnse, A.E.1    Peters, S.L.2    Michel, M.C.3
  • 5
    • 0034614621 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5
    • An, S., Zheng, Y. and Bleu, T. (2000) Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5. Journal of Biological Chemistry, 275, pp. 288-296.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 288-296
    • An, S.1    Zheng, Y.2    Bleu, T.3
  • 6
    • 0037155259 scopus 로고    scopus 로고
    • Extracellular export of sphingosine kinase-1 enzyme: Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation
    • Ancellin, N., Colmont, C., Su, J., Li, Q., Mittereder, N., Chae, S. S., Stefansson, S., Liau, G. and Hla, T. (2002) Extracellular export of sphingosine kinase-1 enzyme: Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation. Journal of Biological Chemistry, 277, pp. 6667-6675.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 6667-6675
    • Ancellin, N.1    Colmont, C.2    Su, J.3    Li, Q.4    Mittereder, N.5    Chae, S.S.6    Stefansson, S.7    Liau, G.8    Hla, T.9
  • 7
    • 34250215321 scopus 로고    scopus 로고
    • The suppressive effect of sphingosine 1-phosphate on monocyte-endothelium adhesion may be mediated by the rearrangement of the endothelial integrins alpha(5)beta(1) and alpha(V)beta(3)
    • Aoki, S., Yatomi, Y., Shimosawa, T., Yamashita, H., Kitayama, J., Tsuno, N. H., Takahashi, K. and Ozaki, Y. (2007) The suppressive effect of sphingosine 1-phosphate on monocyte-endothelium adhesion may be mediated by the rearrangement of the endothelial integrins alpha(5)beta(1) and alpha(V)beta(3). Journal of Thrombosis and Haemostasis, 5, pp. 1292-1301.
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , pp. 1292-1301
    • Aoki, S.1    Yatomi, Y.2    Shimosawa, T.3    Yamashita, H.4    Kitayama, J.5    Tsuno, N.H.6    Takahashi, K.7    Ozaki, Y.8
  • 8
    • 0032532629 scopus 로고    scopus 로고
    • Evidence for the presence of multiple forms of Sph kinase in human platelets
    • Banno, Y., Kato, M., Hara, A. and Nozawa, Y. (1998) Evidence for the presence of multiple forms of Sph kinase in human platelets. Biochemistry Journal, 335, pp. 301-304.
    • (1998) Biochemistry Journal , vol.335 , pp. 301-304
    • Banno, Y.1    Kato, M.2    Hara, A.3    Nozawa, Y.4
  • 9
    • 0019979890 scopus 로고
    • Are lysophosphatidic acids or phosphatidic acids involved in stimulus activation coupling in platelets?
    • Benton, A. M., Gerrard, J. M., Michiel, T. and Kindom, S. E. (1982) Are lysophosphatidic acids or phosphatidic acids involved in stimulus activation coupling in platelets?. Blood, 60, pp. 642-649.
    • (1982) Blood , vol.60 , pp. 642-649
    • Benton, A.M.1    Gerrard, J.M.2    Michiel, T.3    Kindom, S.E.4
  • 12
    • 0042809559 scopus 로고    scopus 로고
    • Sphingosine kinase modulates microvascular tone and myogenic responses through activation of RhoA/Rho kinase
    • Bolz, S. S., Vogel, L., Sollinger, D., Derwand, R., Boer, C., Pitson, S. M., Spiegel, S. and Pohl, U. (2003) Sphingosine kinase modulates microvascular tone and myogenic responses through activation of RhoA/Rho kinase. Circulation, 108, pp. 342-347.
    • (2003) Circulation , vol.108 , pp. 342-347
    • Bolz, S.S.1    Vogel, L.2    Sollinger, D.3    Derwand, R.4    Boer, C.5    Pitson, S.M.6    Spiegel, S.7    Pohl, U.8
  • 13
    • 0029027589 scopus 로고
    • Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: Spatial and temporal modulation of PDGF chemotactic signal transduction
    • Bornfeldt, K. E., Graves, L. M., Raines, E. W., Igarashi, Y., Wayman, G., Yamamura, S., Yatomi, Y., Sidhu, J. S., Krebs, E. G. and Hakomori, S. (1995) Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: Spatial and temporal modulation of PDGF chemotactic signal transduction. Journal of Cell Biology, 130, pp. 193-206.
    • (1995) Journal of Cell Biology , vol.130 , pp. 193-206
    • Bornfeldt, K.E.1    Graves, L.M.2    Raines, E.W.3    Igarashi, Y.4    Wayman, G.5    Yamamura, S.6    Yatomi, Y.7    Sidhu, J.S.8    Krebs, E.G.9    Hakomori, S.10
  • 14
    • 14844284989 scopus 로고    scopus 로고
    • Lipid phosphate phosphatases and related proteins: Signaling functions in development, cell division and cancer
    • Brindley, D. N. (2004) Lipid phosphate phosphatases and related proteins: Signaling functions in development, cell division and cancer. Journal of Cell Biochemistry, 92, pp. 900-912.
    • (2004) Journal of Cell Biochemistry , vol.92 , pp. 900-912
    • Brindley, D.N.1
  • 16
    • 30744469407 scopus 로고    scopus 로고
    • Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets 1 pathway in human fibroblasts
    • Bu, S., Yamanka, M., Pei, H., Bielawska, A., Bielawski, J., Hannun, Y. A., Obeid, L. and Trojanowska, M. (2006) Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets 1 pathway in human fibroblasts. FASEB Journal, 20, pp. 184-186.
    • (2006) FASEB Journal , vol.20 , pp. 184-186
    • Bu, S.1    Yamanka, M.2    Pei, H.3    Bielawska, A.4    Bielawski, J.5    Hannun, Y.A.6    Obeid, L.7    Trojanowska, M.8
  • 17
    • 31844450444 scopus 로고    scopus 로고
    • Targeting Rho and Rho-kinase in the treatment of cardiovascular disease
    • Budzyn, K., Marley, P. D. and Sobey, C. G. (2006) Targeting Rho and Rho-kinase in the treatment of cardiovascular disease. Trends in Pharmacological Science, 27, pp. 97-104.
    • (2006) Trends in Pharmacological Science , vol.27 , pp. 97-104
    • Budzyn, K.1    Marley, P.D.2    Sobey, C.G.3
  • 18
    • 0030592536 scopus 로고    scopus 로고
    • Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity
    • Buehrer, B. M., Bardes, E. S. and Bell, R. M. (1996) Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity. Biochimica et Biophysica Acta, 1303, pp. 233-242.
    • (1996) Biochimica Et Biophysica Acta , vol.1303 , pp. 233-242
    • Buehrer, B.M.1    Bardes, E.S.2    Bell, R.M.3
  • 19
    • 27844517355 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate and ceramide-1-phosphate: Expanding roles in cell signalling
    • Chalfant, C. E. and Spiegel, S. (2005) Sphingosine-1-phosphate and ceramide-1-phosphate: Expanding roles in cell signalling. Journal of Cell Science, 118, pp. 4605-4612.
    • (2005) Journal of Cell Science , vol.118 , pp. 4605-4612
    • Chalfant, C.E.1    Spiegel, S.2
  • 22
    • 0029101772 scopus 로고
    • Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers
    • Collins, T., Read, M. A., Neish, A. S., Whitley, M. Z., Thanos, D. and Maniatis, T. (1995) Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. Federation Proceedings, 9, pp. 899-909.
    • (1995) Federation Proceedings , vol.9 , pp. 899-909
    • Collins, T.1    Read, M.A.2    Neish, A.S.3    Whitley, M.Z.4    Thanos, D.5    Maniatis, T.6
  • 23
    • 0037178737 scopus 로고    scopus 로고
    • Comparison of sphingosine-1-phosphate-induced intracellular signalling pathways in vascular smooth muscles: Differential role in vasoconstriction
    • Coussin, F., Scott, R. H., Wise, A. and Nixon, G. F. (2002) Comparison of sphingosine-1-phosphate-induced intracellular signalling pathways in vascular smooth muscles: Differential role in vasoconstriction. Circulation Research, 91, pp. 151-157.
    • (2002) Circulation Research , vol.91 , pp. 151-157
    • Coussin, F.1    Scott, R.H.2    Wise, A.3    Nixon, G.F.4
  • 24
    • 0029948396 scopus 로고    scopus 로고
    • Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
    • Cuvillier, O., Pirianov, G., Kleuser, B., Vanek, P. G., Coso, O. A., Gutkind, S. and Spiegel, S. (1996) Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature, 381, pp. 800-803.
    • (1996) Nature , vol.381 , pp. 800-803
    • Cuvillier, O.1    Pirianov, G.2    Kleuser, B.3    Vanek, P.G.4    Coso, O.A.5    Gutkind, S.6    Spiegel, S.7
  • 25
    • 0032579414 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas-and ceramide-mediated apoptosis in Jurkat T lymphocytes
    • Cuvillier, O., Rosenthal, D. S., Smulson, M. E. and Spiegel, S. (1998) Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas-and ceramide-mediated apoptosis in Jurkat T lymphocytes. Journal of Biological Chemistry, 273, pp. 2910-2916.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 2910-2916
    • Cuvillier, O.1    Rosenthal, D.S.2    Smulson, M.E.3    Spiegel, S.4
  • 26
    • 15744362906 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate receptors mediate the lipid-induced cAMP accumulation through cyclooxygenase-1/prostaglandin I2 pathway in human coronary artery smooth muscle cells
    • Damirin, A., Tomura, H., Komachi, M., Tobo, M., Sato, K., Mogi, C., Nochi, H., Tamoto, K. and Okajima, F. (2005) Sphingosine 1-phosphate receptors mediate the lipid-induced cAMP accumulation through cyclooxygenase-1/prostaglandin I2 pathway in human coronary artery smooth muscle cells. Molecular Pharmacology, 67, pp. 1177-1185.
    • (2005) Molecular Pharmacology , vol.67 , pp. 1177-1185
    • Damirin, A.1    Tomura, H.2    Komachi, M.3    Tobo, M.4    Sato, K.5    Mogi, C.6    Nochi, H.7    Tamoto, K.8    Okajima, F.9
  • 29
    • 0026457994 scopus 로고
    • Sphingosine-1-phosphate, a metabolite of sphingosine, increases phosphatidic acid levels by phospholipase D activation
    • Desai, N. N., Zhang, H., Olivera, A., Mattie, M. E. and Spiegel, S. (1992) Sphingosine-1-phosphate, a metabolite of sphingosine, increases phosphatidic acid levels by phospholipase D activation. Journal of Biological Chemistry, 267, pp. 23122-23128.
    • (1992) Journal of Biological Chemistry , vol.267 , pp. 23122-23128
    • Desai, N.N.1    Zhang, H.2    Olivera, A.3    Mattie, M.E.4    Spiegel, S.5
  • 32
    • 0035089286 scopus 로고    scopus 로고
    • Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells
    • Edsall, L. C., Cuvillier, O., Twitty, S., Spiegel, S. and Milstien, S. (2001) Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells. Journal of Neurochemistry, 76, pp. 1573-1584.
    • (2001) Journal of Neurochemistry , vol.76 , pp. 1573-1584
    • Edsall, L.C.1    Cuvillier, O.2    Twitty, S.3    Spiegel, S.4    Milstien, S.5
  • 33
    • 0030780015 scopus 로고    scopus 로고
    • Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation
    • Edsall, L. C., Pirianov, G. G. and Spiegel, S. (1997) Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation. Journal of Neuroscience, 17, pp. 6952-6960.
    • (1997) Journal of Neuroscience , vol.17 , pp. 6952-6960
    • Edsall, L.C.1    Pirianov, G.G.2    Spiegel, S.3
  • 34
    • 0032530864 scopus 로고    scopus 로고
    • N'N-Dimethlysphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: Modulation of cellular levels of sphingosine 1-phosphate and ceramide
    • Edsall, L. C., Van Brocklyn, J. R., Cuvillier, O., Kleuser, B. and Spiegel, S. (1998) N'N-Dimethlysphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: Modulation of cellular levels of sphingosine 1-phosphate and ceramide. Biochemistry, 37, pp. 12892-12898.
    • (1998) Biochemistry , vol.37 , pp. 12892-12898
    • Edsall, L.C.1    Van Brocklyn, J.R.2    Cuvillier, O.3    Kleuser, B.4    Spiegel, S.5
  • 35
    • 0027232391 scopus 로고
    • The bioactive phospholipid lysophosphatidic acid is released from activated platelets
    • Eichholtz, T., Jalink, K., Fahrenfort, I. and Moolenaar, W. H. (1993) The bioactive phospholipid lysophosphatidic acid is released from activated platelets. Biochemistry Journal, 291, pp. 677-680.
    • (1993) Biochemistry Journal , vol.291 , pp. 677-680
    • Eichholtz, T.1    Jalink, K.2    Fahrenfort, I.3    Moolenaar, W.H.4
  • 36
    • 12244310530 scopus 로고    scopus 로고
    • Activation of human monocytic cells by lysophosphatidic acid and sphingosine 1-phospahate
    • Fueller, M., Wang, D. A., Tigyi, G. and Siess, W. (2003) Activation of human monocytic cells by lysophosphatidic acid and sphingosine 1-phospahate. Cell Signaling, 15, pp. 367-375.
    • (2003) Cell Signaling , vol.15 , pp. 367-375
    • Fueller, M.1    Wang, D.A.2    Tigyi, G.3    Siess, W.4
  • 37
    • 0025351642 scopus 로고
    • Intracellular calcium release mediated by sphingosine derivatives generated in cells
    • Ghosh, T. K., Bian, J. and Gill, D. L. (1990) Intracellular calcium release mediated by sphingosine derivatives generated in cells. Science, 248, pp. 1653-1656.
    • (1990) Science , vol.248 , pp. 1653-1656
    • Ghosh, T.K.1    Bian, J.2    Gill, D.L.3
  • 38
    • 0032532242 scopus 로고    scopus 로고
    • Differential stimulation of proline-rich tyrosine kinase 2 and mitogen-activated protein kinase by sphingosine 1-phosphate
    • Guo, C., Zheng, C., Martin-Padura, I., Bian, Z. C. and Guan, J. L. (1998) Differential stimulation of proline-rich tyrosine kinase 2 and mitogen-activated protein kinase by sphingosine 1-phosphate. European Journal of Biochemistry, 257, pp. 403-408.
    • (1998) European Journal of Biochemistry , vol.257 , pp. 403-408
    • Guo, C.1    Zheng, C.2    Martin-Padura, I.3    Bian, Z.C.4    Guan, J.L.5
  • 39
    • 0030448021 scopus 로고    scopus 로고
    • Functions of ceramide in coordinating cellular responses to stress
    • Hannun, Y. A. (1996) Functions of ceramide in coordinating cellular responses to stress. Science, 274, pp. 1855-1859.
    • (1996) Science , vol.274 , pp. 1855-1859
    • Hannun, Y.A.1
  • 40
    • 33645840777 scopus 로고    scopus 로고
    • Signal transduction underlying the vascular effects of sphingosine 1-phosphate and sphingosylphosphorylcholine
    • Hemmings, D. G. (2006) Signal transduction underlying the vascular effects of sphingosine 1-phosphate and sphingosylphosphorylcholine. Naunyn-Schmiedeber's Archives of Pharmacology, 373, pp. 18-29.
    • (2006) Naunyn-Schmiedeber's Archives of Pharmacology , vol.373 , pp. 18-29
    • Hemmings, D.G.1
  • 41
  • 42
    • 4744340005 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate-induced vasoconstriction is elevated in mesenteric resistance arteries from aged female rats
    • Hemmings, D. G., Xu, Y. and Davidge, S. T. (2004) Sphingosine 1-phosphate-induced vasoconstriction is elevated in mesenteric resistance arteries from aged female rats. British Journal of Pharmacology, 143, pp. 276-284.
    • (2004) British Journal of Pharmacology , vol.143 , pp. 276-284
    • Hemmings, D.G.1    Xu, Y.2    Davidge, S.T.3
  • 43
    • 0025311299 scopus 로고
    • An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors
    • Hla, T. and Maciag, T. (1990) An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors. Journal of Biological Chemistry, 265, pp. 9308-9313.
    • (1990) Journal of Biological Chemistry , vol.265 , pp. 9308-9313
    • Hla, T.1    Maciag, T.2
  • 44
    • 0033635733 scopus 로고    scopus 로고
    • BH3-Only proteins-essential initiators of apoptotic cell death
    • Huang, D. C. and Strasser, A. (2000) BH3-Only proteins-essential initiators of apoptotic cell death. Cell, 103, pp. 839-842.
    • (2000) Cell , vol.103 , pp. 839-842
    • Huang, D.C.1    Strasser, A.2
  • 45
    • 0035853775 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate and activation of endothelial nitric oxide synthase: Differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells
    • Igarashi, J., Bernier, S. G. and Michel, T. (2001) Sphingosine-1-phosphate and activation of endothelial nitric oxide synthase: Differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells. Journal of Biological Chemistry, 276, pp. 12420-12426.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 12420-12426
    • Igarashi, J.1    Bernier, S.G.2    Michel, T.3
  • 46
    • 0024436946 scopus 로고
    • Enzymatic synthesis of N,N′-dimethylsphingosine: Demonstration of the sphingoisne: N-methyltransferase in mouse brain
    • Igarashi, Y. and Hakomori, S. (1989) Enzymatic synthesis of N,N′-dimethylsphingosine:dEmonstration of the sphingoisne: N-methyltransferase in mouse brain. Biochemical and Biophysical Research Communications, 164, pp. 1411-1416.
    • (1989) Biochemical and Biophysical Research Communications , vol.164 , pp. 1411-1416
    • Igarashi, Y.1    Hakomori, S.2
  • 48
    • 0037067769 scopus 로고    scopus 로고
    • Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P (2)/LP (B2)/ EDG-5 and S1P(3)/LP(B3)/EDG-3
    • Ishii, I., Ye, X., Friedman, B., Kawamura, S., Contos, J. J., Kingsbury, M. A., Yang, A. H., Zhang, G., Brown, J. H. and Chun, J. (2002) Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P (2)/LP (B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3. Journal of Biological Chemistry, 277, pp. 25152-25159.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 25152-25159
    • Ishii, I.1    Ye, X.2    Friedman, B.3    Kawamura, S.4    Contos, J.J.5    Kingsbury, M.A.6    Yang, A.H.7    Zhang, G.8    Brown, J.H.9    Chun, J.10
  • 51
    • 0014663267 scopus 로고
    • The in vitro degradation of dihydrosphingosine
    • Keenan, R. W. and Maxam, A. (1969) The in vitro degradation of dihydrosphingosine. Biochimica et Biophysica Acta, 176, pp. 348-356.
    • (1969) Biochimica Et Biophysica Acta , vol.176 , pp. 348-356
    • Keenan, R.W.1    Maxam, A.2
  • 52
    • 0025045879 scopus 로고
    • Protein kinase C and platelet inhibition by D-erythro-sphingosine: Comparison with N
    • Khan, W. A., Dobrowsky, R., el Touny, S. and Hannun, Y. A. (1990) Protein kinase C and platelet inhibition by D-erythro-sphingosine: comparison with N.,N-dimethylsphingosine and commercial prepearation. Biochemical and Biophysical Research Communications, 172, pp. 683-691.
    • (1990) Biochemical and Biophysical Research Communications , vol.172 , pp. 683-691
    • Khan, W.A.1    Dobrowsky, R.2    el Touny, S.3    Hannun, Y.A.4
  • 53
    • 0035943594 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate may be a major component of plasma lipoproteins responsible for the cytoprotective actions in human umbilical vein endothelial cells
    • Kimura, T., Sato, K., Kuwubara, A., Tomura, H., Ishiwara, M., Kobayashi, I., Ui, M. and Okajima, F. (2001) Sphingosine-1-phosphate may be a major component of plasma lipoproteins responsible for the cytoprotective actions in human umbilical vein endothelial cells. Journal of Biological Chemistry, 276, pp. 31780-31785.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 31780-31785
    • Kimura, T.1    Sato, K.2    Kuwubara, A.3    Tomura, H.4    Ishiwara, M.5    Kobayashi, I.6    Ui, M.7    Okajima, F.8
  • 55
    • 0037162037 scopus 로고    scopus 로고
    • Signaling of sphingosine 1-phosphate via the S1P/EDG family of G-protein coupled receptors
    • Kluk, M. J. and Hla, T. (2002) Signaling of sphingosine 1-phosphate via the S1P/EDG family of G-protein coupled receptors. Biochimica et Biophysica Acta, 1582, pp. 72-80.
    • (2002) Biochimica Et Biophysica Acta , vol.1582 , pp. 72-80
    • Kluk, M.J.1    Hla, T.2
  • 58
    • 0033615537 scopus 로고    scopus 로고
    • Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate
    • Lee, M. J., Thangada, S., Claffey, K. P., Ancellin, N., Liu, C. H., Kluk, M., Volpi, M., Sha'afi, R. J. and Hla, T. (1999) Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate. Cell, 99, pp. 301-312.
    • (1999) Cell , vol.99 , pp. 301-312
    • Lee, M.J.1    Thangada, S.2    Claffey, K.P.3    Ancellin, N.4    Liu, C.H.5    Kluk, M.6    Volpi, M.7    Sha'afi, R.J.8    Hla, T.9
  • 59
    • 0032489574 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1
    • Lee, M. J., Van Brocklyn, J. R., Thangada, S., Liu, C. H., Hand, A. R. Menzeleev, R. et al. (1998) Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science, 279, pp. 1552-1555.
    • (1998) Science , vol.279 , pp. 1552-1555
    • Lee, M.J.1    Van Brocklyn, J.R.2    Thangada, S.3    Liu, C.H.4    Hand, A.R.5    Menzeleev, R.6
  • 60
  • 61
    • 0008206988 scopus 로고    scopus 로고
    • TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival
    • Lee, S. Y., Reichlin, A., Santana, A., Sokol, K. A., Nussenzweig, M. C. and Choi, Y. (1997) TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival. Immunity, 7, pp. 703-713.
    • (1997) Immunity , vol.7 , pp. 703-713
    • Lee, S.Y.1    Reichlin, A.2    Santana, A.3    Sokol, K.A.4    Nussenzweig, M.C.5    Choi, Y.6
  • 63
    • 29144510550 scopus 로고    scopus 로고
    • Inhibitory effects of sphingosine-1-phosphate on proliferation of PC3 human prostate cancer cells
    • Liao, J. J., Huang, Y. T. and Lee, H. (2005) Inhibitory effects of sphingosine-1-phosphate on proliferation of PC3 human prostate cancer cells. Zoological Studies, 44, pp. 219-227.
    • (2005) Zoological Studies , vol.44 , pp. 219-227
    • Liao, J.J.1    Huang, Y.T.2    Lee, H.3
  • 64
    • 17044371645 scopus 로고    scopus 로고
    • Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members
    • Limaye, V., Li, X., Hahn, C., Xia, P., Berndt, M. C., Vadas, M. A. and Gamble, J. R. (2005) Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members. Blood, 105, pp. 3169-3177.
    • (2005) Blood , vol.105 , pp. 3169-3177
    • Limaye, V.1    Li, X.2    Hahn, C.3    Xia, P.4    Berndt, M.C.5    Vadas, M.A.6    Gamble, J.R.7
  • 65
    • 0034733556 scopus 로고    scopus 로고
    • Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform
    • Liu, H., Sugiura, M., Nava, V. E., Edsall, L. C., Kono, K. Poulton, S. et al. (2000) Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform. Journal of Biological Chemistry, 275, pp. 19513-19520.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 19513-19520
    • Liu, H.1    Sugiura, M.2    Nava, V.E.3    Edsall, L.C.4    Kono, K.5    Poulton, S.6
  • 67
  • 71
    • 0028300922 scopus 로고
    • Regulatory effect of phorbol esters on sphingosine kinase in BALB/C 3T3 fibroblasts (variant A31): Demonstration of cell type-specific response-a preliminary note
    • Mazurek, N., Megidish, T., Hakomori, S. and Igarashi, Y. (1994) Regulatory effect of phorbol esters on sphingosine kinase in BALB/C 3T3 fibroblasts (variant A31): Demonstration of cell type-specific response-a preliminary note. Biochemical and Biophysical Research Communications, 198, pp. 1-9.
    • (1994) Biochemical and Biophysical Research Communications , vol.198 , pp. 1-9
    • Mazurek, N.1    Megidish, T.2    Hakomori, S.3    Igarashi, Y.4
  • 73
    • 0032540010 scopus 로고    scopus 로고
    • FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking
    • Melendez, A., Floto, R. A., Gillooly, D. J., Harnett, M. M. and Allen, J. M. (1998) FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking. Journal of Biological Chemistry, 273, pp. 9393-9402.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 9393-9402
    • Melendez, A.1    Floto, R.A.2    Gillooly, D.J.3    Harnett, M.M.4    Allen, J.M.5
  • 74
    • 0037162052 scopus 로고    scopus 로고
    • Sphingosylphosphorylcholine-biological functions and mechanisms of action
    • Meyer, Z. u., Herringdorf, D., Himmel, H. M. and Jakobs, K. H. (2002) Sphingosylphosphorylcholine-biological functions and mechanisms of action. Biochimica et Biophysica Acta, 1582, pp. 178-189.
    • (2002) Biochimica Et Biophysica Acta , vol.1582 , pp. 178-189
    • Meyer, Z.1    Herringdorf, D.2    Himmel, H.M.3    Jakobs, K.H.4
  • 77
    • 36849066265 scopus 로고    scopus 로고
    • Effects of sphingosine-1-phosphate and sphingosylphosphorylcholine on intracellular Ca2+ and cell death in prostate cancer cell lines
    • Mulders, A. C. M., Nau, S., Li, Y. and Michel, M. C. (2007) Effects of sphingosine-1-phosphate and sphingosylphosphorylcholine on intracellular Ca2+ and cell death in prostate cancer cell lines. Autonomic and Autacoid Pharmacology, 27, pp. 173-179.
    • (2007) Autonomic and Autacoid Pharmacology , vol.27 , pp. 173-179
    • Mulders, A.C.M.1    Nau, S.2    Li, Y.3    Michel, M.C.4
  • 78
    • 0034672133 scopus 로고    scopus 로고
    • Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions
    • Murata, N., Sato, K., Kon, J., Tomura, H., Yanagita, M., Kuwabara, A., Ui, M. and Okajima, F. (2000) Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions. Biochemistry Journal, 352, pp. 809-815.
    • (2000) Biochemistry Journal , vol.352 , pp. 809-815
    • Murata, N.1    Sato, K.2    Kon, J.3    Tomura, H.4    Yanagita, M.5    Kuwabara, A.6    Ui, M.7    Okajima, F.8
  • 80
    • 33645768167 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase and partial reactivation fot eh cell cycle by cis-4-methyl sphingosine direct on postmitotic neurons towards apoptosis
    • Naetzker, S., Hagen, N. and Echten-Deckert, G. (2006) Activation of p38 mitogen-activated protein kinase and partial reactivation fot eh cell cycle by cis-4-methyl sphingosine direct on postmitotic neurons towards apoptosis. Genes Cells, 11, pp. 269-279.
    • (2006) Genes Cells , vol.11 , pp. 269-279
    • Naetzker, S.1    Hagen, N.2    Echten-Deckert, G.3
  • 81
    • 0032584739 scopus 로고    scopus 로고
    • The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases
    • Nagiec, M. M., Skrzypek, M., Nagiec, E. E., Lester, R. L. and Dickson, R. C. (1998) The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases. Journal of Biological Chemistry, 273, pp. 19437-19442.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 19437-19442
    • Nagiec, M.M.1    Skrzypek, M.2    Nagiec, E.E.3    Lester, R.L.4    Dickson, R.C.5
  • 83
    • 0036436697 scopus 로고    scopus 로고
    • Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer MCF-7 cells
    • Nava, V. E., Hobson, J. P., Murthy, S., Milstein, S. and Spiegel, S. (2002) Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer MCF-7 cells. Experimental Cell Research, 281, pp. 115-127.
    • (2002) Experimental Cell Research , vol.281 , pp. 115-127
    • Nava, V.E.1    Hobson, J.P.2    Murthy, S.3    Milstein, S.4    Spiegel, S.5
  • 85
    • 26444511231 scopus 로고    scopus 로고
    • Atheroprotective effects of high-density lipoprotein-associated lysosphingolipids
    • Nofer, J. R. and Assmann, G. (2005) Atheroprotective effects of high-density lipoprotein-associated lysosphingolipids. Trends in Cardiovascular Medicine, 15, pp. 265-271.
    • (2005) Trends in Cardiovascular Medicine , vol.15 , pp. 265-271
    • Nofer, J.R.1    Assmann, G.2
  • 87
    • 0037162038 scopus 로고    scopus 로고
    • Plasma lipoproteins behave as carriers of extracellular sphingosine 1-phosphate: Is this an atherogenic mediator or an anti-atherogenic mediator?
    • Okajima, F. (2002) Plasma lipoproteins behave as carriers of extracellular sphingosine 1-phosphate: Is this an atherogenic mediator or an anti-atherogenic mediator?. Biochimica et Biophysica Acta, 1582, pp. 132-137.
    • (2002) Biochimica Et Biophysica Acta , vol.1582 , pp. 132-137
    • Okajima, F.1
  • 90
    • 0027371722 scopus 로고
    • Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens
    • Olivera, A. and Spiegel, S. (1993) Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature, 365, pp. 557-560.
    • (1993) Nature , vol.365 , pp. 557-560
    • Olivera, A.1    Spiegel, S.2
  • 91
    • 29244457577 scopus 로고    scopus 로고
    • Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models
    • Pchejetski, D., Golzio, M. and Bonhoure, E. (2005) Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models. Cancer Research, 65, pp. 1167-1175.
    • (2005) Cancer Research , vol.65 , pp. 1167-1175
    • Pchejetski, D.1    Golzio, M.2    Bonhoure, E.3
  • 94
    • 0034721844 scopus 로고    scopus 로고
    • Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation
    • Pitson, S. M., Moretti, P. A., Zebol, J. R., Xia, P., Gamble, J. R., Vadas, M. A., D'Andrea, R. J. and Wattenberg, B. W. (2000) Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase. Journal of Biological Chemistry, 275, pp. 33945-33950.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 33945-33950
    • Pitson, S.M.1    Moretti, P.A.2    Zebol, J.R.3    Xia, P.4    Gamble, J.R.5    Vadas, M.A.6    D'Andrea, R.J.7    Wattenberg, B.W.8
  • 98
    • 0034661482 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate signalling in mammalian cells
    • Pyne, S. and Pyne, N. J. (2000) Sphingosine 1-phosphate signalling in mammalian cells. Biochemistry Journal, 349, pp. 385-402.
    • (2000) Biochemistry Journal , vol.349 , pp. 385-402
    • Pyne, S.1    Pyne, N.J.2
  • 99
    • 0030728721 scopus 로고    scopus 로고
    • Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors
    • Rius, R. A., Edsall, L. C. and Spiegel, S. (1997) Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors. FEBS Letters, 417, pp. 173-176.
    • (1997) FEBS Letters , vol.417 , pp. 173-176
    • Rius, R.A.1    Edsall, L.C.2    Spiegel, S.3
  • 100
    • 0028978626 scopus 로고
    • TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40
    • Rothe, M., Sarma, V., Dixit, V. M. and Goeddel, D. V. (1995) TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40. Science, 269, pp. 1424-1427.
    • (1995) Science , vol.269 , pp. 1424-1427
    • Rothe, M.1    Sarma, V.2    Dixit, V.M.3    Goeddel, D.V.4
  • 102
    • 0032896375 scopus 로고    scopus 로고
    • Possible involvement of cell surface receptors in sphingosine 1-phosphate-induced activation of extracellular signal-regulated kinase in C6 glioma cells
    • Sato, K., Tomura, H., Igarashi, Y., Ui, M. and Okajima, F. (1999) Possible involvement of cell surface receptors in sphingosine 1-phosphate-induced activation of extracellular signal-regulated kinase in C6 glioma cells. Molecular Pharmacology, 55, pp. 126-133.
    • (1999) Molecular Pharmacology , vol.55 , pp. 126-133
    • Sato, K.1    Tomura, H.2    Igarashi, Y.3    Ui, M.4    Okajima, F.5
  • 104
    • 1642416885 scopus 로고    scopus 로고
    • HDL action on the vascular wall: Is the answer NO?
    • Shaul, P. W. and Mineo, C. (2004) HDL action on the vascular wall: Is the answer NO?. Journal of Clinical Investigation, 113, pp. 509-513.
    • (2004) Journal of Clinical Investigation , vol.113 , pp. 509-513
    • Shaul, P.W.1    Mineo, C.2
  • 107
    • 0014784615 scopus 로고
    • Metabolism of sphingosine bases
    • Stoffel, W., Assmann, G. and Binczek, E. (1970) Metabolism of sphingosine bases. 13. Enzymatic synthesis of 1-phosphate esters of 4t-sphingenine (sphingosine), sphinganine (dihydrosphingosine), 4-hydroxysphinganine (phytosphingosine) and 3-dehydrosphinganine by erythrocytes. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 351, pp. 635-642.
    • (1970) Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie , vol.351 , pp. 635-642
    • Stoffel, W.1    Assmann, G.2    Binczek, E.3
  • 110
    • 0028322142 scopus 로고
    • Sphingosine 1-phosphate, a novel signaling molecule, stimulates DNA binding activity of AP-1 in quiescent Swiss 3T3 fibroblasts
    • Su, Y., Rosenthal, D., Smulson, M. and Spiegel, S. (1994) Sphingosine 1-phosphate, a novel signaling molecule, stimulates DNA binding activity of AP-1 in quiescent Swiss 3T3 fibroblasts. Journal of Biological Chemistry, 269, pp. 16512-16517.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 16512-16517
    • Su, Y.1    Rosenthal, D.2    Smulson, M.3    Spiegel, S.4
  • 112
    • 33645801577 scopus 로고    scopus 로고
    • Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: Modulation of sphingolipid levels and the induction of apoptosis
    • Taha, T. A., Kitatani, K., el Alwani, M., Bielawski, J., Hannun, Y. A. and Obeid, L. M. (2006) Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: Modulation of sphingolipid levels and the induction of apoptosis. FASEB Journal, 20, pp. 482-484.
    • (2006) FASEB Journal , vol.20 , pp. 482-484
    • Taha, T.A.1    Kitatani, K.2    el Alwani, M.3    Bielawski, J.4    Hannun, Y.A.5    Obeid, L.M.6
  • 113
    • 34548700158 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate (S1P) inhibits monocyte-endothelial cell interaction by regulating of RhoA activity
    • Tani, M., Kawakami, A., Nagai, M., Shimokado, K., Kondo, K. and Yoshida, M. (2007) Sphingosine 1-phosphate (S1P) inhibits monocyte-endothelial cell interaction by regulating of RhoA activity. FEBS Letters, 581, pp. 4621-4626.
    • (2007) FEBS Letters , vol.581 , pp. 4621-4626
    • Tani, M.1    Kawakami, A.2    Nagai, M.3    Shimokado, K.4    Kondo, K.5    Yoshida, M.6
  • 114
    • 14844349788 scopus 로고    scopus 로고
    • Sphingosine kinase 1 (SK1) is recruited to nascent phagosomes in human macrophages: Inhibition of SK1 translocation by Mycobacterium tuberculosis
    • Thompson, C. R., Iyer, S. S., Melrose, N., VanOosten, R., Johnson, K., Pitson, S. M., Obeid, L. M. and Kusner, D. J. (2005) Sphingosine kinase 1 (SK1) is recruited to nascent phagosomes in human macrophages: Inhibition of SK1 translocation by Mycobacterium tuberculosis. Journal of Immunology, 174, pp. 3551-3561.
    • (2005) Journal of Immunology , vol.174 , pp. 3551-3561
    • Thompson, C.R.1    Iyer, S.S.2    Melrose, N.3    VanOosten, R.4    Johnson, K.5    Pitson, S.M.6    Obeid, L.M.7    Kusner, D.J.8
  • 117
    • 0025743953 scopus 로고
    • Subcellular localization and membrane topology of sphingosine-1-phosphate lyase in rat liver
    • Van Veldhoven, P. P. and Mannaerts, G. P. (1991) Subcellular localization and membrane topology of sphingosine-1-phosphate lyase in rat liver. Journal of Biological Chemistry, 266, pp. 12502-12507.
    • (1991) Journal of Biological Chemistry , vol.266 , pp. 12502-12507
    • Van Veldhoven, P.P.1    Mannaerts, G.P.2
  • 120
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang, C. Y., Mayo, M. W., Korneluk, R. G., Goeddel, D. V. and Baldwin Jr., A. S. (1998) NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science, 281, pp. 1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin Jr., A.S.5
  • 121
    • 0030968768 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate stimulates rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts
    • Wang, F., Nobes, C. D., Hall, A. and Spiegel, S. (1997) Sphingosine 1-phosphate stimulates rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts. Biochemistry Journal, 324, pp. 481-488.
    • (1997) Biochemistry Journal , vol.324 , pp. 481-488
    • Wang, F.1    Nobes, C.D.2    Hall, A.3    Spiegel, S.4
  • 123
    • 33744807983 scopus 로고    scopus 로고
    • The sphingosine diacylglycerol kinase superfamily of signalling kinases: Localization as a key to signalling function
    • Wattenberg, B. W., Pitson, S. M. and Raben, D. M. (2006) The sphingosine diacylglycerol kinase superfamily of signalling kinases: Localization as a key to signalling function. Journal of Lipid Research, 47, pp. 1128-1139.
    • (2006) Journal of Lipid Research , vol.47 , pp. 1128-1139
    • Wattenberg, B.W.1    Pitson, S.M.2    Raben, D.M.3
  • 126
    • 0032723117 scopus 로고    scopus 로고
    • High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway
    • Xia, P., Vadas, M. A., Rye, K. A., Barter, P. J. and Gamble, J. R. (1999) High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL. Journal of Biological Chemistry, 274, pp. 33143-33147.
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 33143-33147
    • Xia, P.1    Vadas, M.A.2    Rye, K.A.3    Barter, P.J.4    Gamble, J.R.5
  • 127
    • 0033607517 scopus 로고    scopus 로고
    • Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells
    • Xia, P., Wang, L., Gamble, J. R. and Vadas, M. A. (1999) Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells. Journal of Biological Chemistry, 274, pp. 34499-34505.
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 34499-34505
    • Xia, P.1    Wang, L.2    Gamble, J.R.3    Vadas, M.A.4
  • 129
    • 0037378735 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate receptor agonism impairs the efficacy of the local immune response by altering trafficking of naive and antigen-activated CD4+ T cells
    • Xie, J. H., Nomura, N., Koprak, S. L., Quackenbush, E. J., Forrest, M. J. and Rosen, H. (2003) Sphingosine-1-phosphate receptor agonism impairs the efficacy of the local immune response by altering trafficking of naive and antigen-activated CD4+ T cells. Journal of Immunology, 170, pp. 3662-3670.
    • (2003) Journal of Immunology , vol.170 , pp. 3662-3670
    • Xie, J.H.1    Nomura, N.2    Koprak, S.L.3    Quackenbush, E.J.4    Forrest, M.J.5    Rosen, H.6
  • 130
    • 35048835160 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate rapidly increases endothelial barrier function independently of VE-cadherin but requires cell spreading and Rho kinase
    • Xu, M., Waters, C. L., Hu, C., Wysolmerski, R. B., Vincent, P. A. and Minnear, F. L. (2007) Sphingosine-1-phosphate rapidly increases endothelial barrier function independently of VE-cadherin but requires cell spreading and Rho kinase. American Journal Physiology and Cell Physiology, 293, pp. C1309-C13018.
    • (2007) American Journal Physiology and Cell Physiology , vol.293
    • Xu, M.1    Waters, C.L.2    Hu, C.3    Wysolmerski, R.B.4    Vincent, P.A.5    Minnear, F.L.6
  • 131
    • 42349117330 scopus 로고    scopus 로고
    • Activation of sphingosine kinase-1 mediates induction of endothelial cell proliferatin and angiogneesis by epoxyeicosatrienoic acids
    • Yan, G., Chen, S., You, B. and Sun, J. (2008) Activation of sphingosine kinase-1 mediates induction of endothelial cell proliferatin and angiogneesis by epoxyeicosatrienoic acids. Cardiovascular Research, 78:2, pp. 308-314.
    • (2008) Cardiovascular Research , vol.78 , Issue.2 , pp. 308-314
    • Yan, G.1    Chen, S.2    You, B.3    Sun, J.4
  • 133
    • 0030961305 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum
    • Yatomi, Y., Igarashi, Y., Yang, L., Hisano, N., Qi, R., Asazuma, N., Satoh, K., Ozaki, Y. and Kume, S. (1997) Sphingosine-1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum. Journal of Biochemistry (Tokyo), 121, pp. 969-973.
    • (1997) Journal of Biochemistry (Tokyo) , vol.121 , pp. 969-973
    • Yatomi, Y.1    Igarashi, Y.2    Yang, L.3    Hisano, N.4    Qi, R.5    Asazuma, N.6    Satoh, K.7    Ozaki, Y.8    Kume, S.9
  • 134
    • 0029052921 scopus 로고
    • Sphingosine-1-phosphate: A platelet-activating sphingolipid released from agonist-stimulated human platelets
    • Yatomi, Y., Ruan, F., Hakomori, S. and Igarashi, Y. (1995) Sphingosine-1-phosphate: A platelet-activating sphingolipid released from agonist-stimulated human platelets. Blood, 86, pp. 193-202.
    • (1995) Blood , vol.86 , pp. 193-202
    • Yatomi, Y.1    Ruan, F.2    Hakomori, S.3    Igarashi, Y.4
  • 135
    • 0031040704 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid
    • Yatomi, Y., Yamamura, S., Ruan, F. and Igarashi, Y. (1997) Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid. Journal of Biological Chemistry, 272, pp. 5291-5297.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 5291-5297
    • Yatomi, Y.1    Yamamura, S.2    Ruan, F.3    Igarashi, Y.4
  • 136
    • 0033197872 scopus 로고    scopus 로고
    • The structural basis for the recognition of diverse receptor sequences by TRAF2
    • Ye, H., Park, Y. C., Kreishman, M., Kieff, E. and Wu, H. (1999) The structural basis for the recognition of diverse receptor sequences by TRAF2. Molecular Cell, 4, pp. 321-330.
    • (1999) Molecular Cell , vol.4 , pp. 321-330
    • Ye, H.1    Park, Y.C.2    Kreishman, M.3    Kieff, E.4    Wu, H.5
  • 137
    • 0034255487 scopus 로고    scopus 로고
    • Thermodynamic characterization of the interaction between TRAF2 and tumor necrosis factor receptor peptides by isothermal titration calorimetry
    • Ye, H. and Wu, H. (2000) Thermodynamic characterization of the interaction between TRAF2 and tumor necrosis factor receptor peptides by isothermal titration calorimetry. Procedings of the National Academy of Sciences of the United States of America, 97, pp. 8961-8966.
    • (2000) Procedings of the National Academy of Sciences of the United States of America , vol.97 , pp. 8961-8966
    • Ye, H.1    Wu, H.2
  • 140
    • 0032031519 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1
    • Zondag, G. C., Postma, F. R., Etten, I. V., Verlaan, I. and Moolenaar, W. H. (1998) Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1. Biochemistry Journal, 330, pp. 605-609.
    • (1998) Biochemistry Journal , vol.330 , pp. 605-609
    • Zondag, G.C.1    Postma, F.R.2    Etten, I.V.3    Verlaan, I.4    Moolenaar, W.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.