1α,25-dihydroxyvitamin D3 protects human keratinocytes from apoptosis by the formation of sphingosine-1-phosphate

Journal of Investigative Dermatology

Volumn 117, Issue 5, 2001, Pages 1241-1249

  Manggau, Marianti ^a   Kim, Dong Seok ^a   Ruwisch, Lars ^a   Vogler, Rüdiger ^a   Korting, Hans Christian ^b   Schäfer Korting, Monika ^a   Kleuser, Burkhard ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Bcl 2 family; Cytoprotection; Programmed cell death; Sphingolipids; Vitamin D3

Indexed keywords

1-HYDROXYCHOLECALCIFEROL; ALFACALCIDOL; CALCITRIOL; CERAMIDE; DRUG DERIVATIVE; HYDROXYCOLECALCIFEROL; LYSOPHOSPHOLIPID; N,N DIMETHYLSPHINGOSINE; N,N-DIMETHYLSPHINGOSINE; PHOSPHOTRANSFERASE; PROTEIN BCL 2; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE KINASE; TUMOR NECROSIS FACTOR ALPHA; CERAMIDE DERIVATIVE; COLECALCIFEROL; PHOSPHOTRANSFERASE INHIBITOR; SPHINGOLIPID;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; CELL PROTECTION; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; HUMAN; KERATINOCYTE; METABOLISM; NECROSIS; PATHOLOGY; PHYSIOLOGY; RADIATION EXPOSURE; ULTRAVIOLET RADIATION; CELL DIFFERENTIATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GROWTH DISORDER; HUMAN CELL; PRECURSOR; PREVENTION; PRIORITY JOURNAL; PSORIASIS VULGARIS; SKIN DISEASE; ULTRAVIOLET IRRADIATION;

APOPTOSIS; CALCITRIOL; CELL DIVISION; CELL SURVIVAL; CELLS, CULTURED; CERAMIDES; CYTOPROTECTION; HUMANS; HYDROXYCHOLECALCIFEROLS; KERATINOCYTES; LYSOPHOSPHOLIPIDS; NECROSIS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTO-ONCOGENE PROTEINS C-BCL-2; SPHINGOSINE; TUMOR NECROSIS FACTOR-ALPHA; ULTRAVIOLET RAYS;

EID: 0035542735     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-202x.2001.01496.x     Document Type: Article

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