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Volumn 277, Issue 28, 2002, Pages 25152-25159

Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P2/LPB2/EDG-5 and S1P3/LPB3/EDG-3

(10) Ishii, Isao a Ye, Xiaoqin a Friedman, Beth b Kawamura, Shuji a Contos, James J A a Kingsbury, Marcy A b Yang, Amy H c Zhang, Guangfa a Brown, Joan Heller a Chun, Jerold b,c

a UNIVERSITY OF CALIFORNIA (United States)

b NATIONAL INSTITUTE OF NEUROSCIENCE (Japan)

c MERCK RESEARCH LABORATORIES (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; ENZYME INHIBITION; PROTEINS; SIGNALING;

PERINATAL LETHALITY;

BIOCHEMISTRY;

ADENYLATE CYCLASE; CALCIUM ION; FORSKOLIN; MEMBRANE RECEPTOR; PHOSPHOLIPASE C; PROTEIN EDG3; PROTEIN EDG5; PROTEIN LPB2; PROTEIN LPB3; PROTEIN S1P2; PROTEIN S1P3; RECEPTOR PROTEIN; RECEPTOR SUBTYPE; RHO FACTOR; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM MOBILIZATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; GENE DELETION; LETHALITY; MALE; MOUSE; NONHUMAN; PERINATAL DEATH; PHENOTYPE; PHOSPHATE METABOLISM; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR BINDING; SIGNAL TRANSDUCTION; WILD TYPE;

ADENYLATE CYCLASE; ANIMALS; BASE SEQUENCE; CALCIUM; DNA PRIMERS; DNA-BINDING PROTEINS; FEMALE; GENES, LETHAL; I-KAPPA B PROTEINS; LITTER SIZE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, LYSOPHOSPHOLIPID; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0037067769 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M200137200 Document Type: Article

Times cited : (223)

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