Sphingosine Kinase Transmits Estrogen Signaling in Human Breast Cancer Cells

Molecular Endocrinology

Volumn 17, Issue 10, 2003, Pages 2002-2012

  Sukocheva, Olga A ^a   Wang, Lijun ^a   Albanese, Nathaniel ^a   Pitson, Stuart M ^a   Vadas, Mathew A ^a   Xia, Pu ^a,b  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AGAR; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; SPHINGOSINE KINASE;

ARTICLE; BREAST CANCER; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CANCER CELL; CANCER GROWTH; CELL GROWTH; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MITOGENESIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOLID; STIMULATION; TRANSCRIPTION INITIATION;

ANTINEOPLASTIC AGENTS, HORMONAL; BREAST NEOPLASMS; CALCIUM; CELL DIVISION; CELL LINE, TUMOR; ENZYME ACTIVATION; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGEN RECEPTOR MODULATORS; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN BINDING; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION; TRANSFECTION;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0142056955     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2003-0119     Document Type: Article

References (45)

1. Hall JM, Couse JF, Korach KS 2001 The multifaceted mechanisms of estradiol and estrogen receptor signaling. J Biol Chem 276:36869-36872
2. Segars JH, Driggers PH 2002 Estrogen action and cytoplasmic signaling cascades. Part I: membrane-associated signaling complexes. Trends Endocrinol Metab 13:349-354
3. Morley P, Whitfield JF, Vanderhyden BC, Tsang BK, Schwartz JL 1992 A new, nongenomic estrogen action: the rapid release of intracellular calcium. Endocrinology 131:1305-1312
4. Gu Q, Moss RL 1996 17βEstradiol potentiates kainate-induced currents via activation of the cAMP cascade. J Neurosci 16:3620-3629
5. Improta-Brears T, Whorton AR, Codazzi F, York JD, Meyer T, McDonnell DP 1999 Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium. Proc Natl Acad Sci USA 96:4686-4691
6. Filardo EJ, Quinn JA, Bland KI, Frackelton AR 2000 Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Mol Endocrinol 14:1649-1660
7. Migliaccio A, Di Domenico M, Castoria G, De Falco A, Bontempo P, Nola E, Auricchio F 1996 Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells. EMBO J 15:1292-1300
8. Wade CB, Robinson S, Shapiro RA, Dorsa DM 2001 Estrogen receptor (ER)α and ERβ exhibit unique pharmacologic properties when coupled to activation of the mitogen-activated protein kinase pathway. Endocrinology 142:2336-2342
9. Benten WP, Stephan C, Lieberherr M, Wunderlich F 2001 Estradiol signaling via sequestrable surface receptors. Endocrinology 142:1669-1677
10. Razandi M, Pedram A, Park ST, Levin ER 2003 Proximal events in signaling by plasma membrane estrogen receptors. J Biol Chem 278:2701-2712
11. Wyckoff MH, Chambliss KL, Mineo C, Yuhanna IS, Mendelsohn ME, Mumby SM, Shaul PW 2001 Plasma membrane estrogen receptors are coupled to endothelial nitric-oxide synthase through Gα(i). J Biol Chem 276:27071-27076
12. Pratt MA, Satkunaratnam A, Novosad DM 1998 Estrogen activates raf-1 kinase and induces expression of Egr-1 in MCF-7 breast cancer cells. Mol Cell Biochem 189: 119-125
13. Castoria G, Migliaccio A, Bilancio A, Di Domenico M, De Falco A, Lombardi M, Fiorentino R, Varricchio L, Barone MV, Auricchio F 2001 PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells. EMBO J 20:6050-6059
14. Farhat MY, Abi-Younes S, Dingaan B, Vargas R, Ramwell PW 1996 Estradiol increases cyclic adenosine monophosphate in rat pulmonary vascular smooth muscle cells by a nongenomic mechanism. J Pharmacol Exp Ther 276:652-657
15. Keshamouni VG, Mattingly RR, Reddy KB 2002 Mechanism of 17-β-estradiol-induced Erk1/2 activation in breast cancer cells. A role for HER2 AND PKC-δ. J Biol Chem 277:22558-22565
16. Spiegel S, Milstien S 2002 Sphingosine 1-phosphate, a key cell signaling molecule. J Biol Chem 277:25851-25854
17. Pyne S, Pyne NJ 2000 Sphingosine 1-phosphate signalling in mammalian cells. Biochem J 349:385-402
18. Spiegel S, Cuvillier O, Edsall LC, Kohama T, Menzeleev R, Olah Z, Olivera A, Pirianov G, Thomas DM, Tu Z, Van Brocklyn JR, Wang F 1998 Sphingosine-1-phosphate in cell growth and cell death. Ann NY Acad Sci 845:11-18
19. Zhang H, Desai NN, Olivera A, Seki T, Brooker G, Spiegel S 1991 Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation. J Cell Biol 114:155-167
20. Olivera A, Kohama T, Edsall L, Nava V, Cuvillier O, Poulton S, Spiegel S 1999 Sphingosine kinase expression increases intracellular sphingosine-1- phosphate and promotes cell growth and survival. J Cell Biol 147:545-558
21. Xia P, Gamble JR, Wang L, Pitson SM, Moretti PA, Wattenberg BW, D'andrea RJ, Vadas MA 2000 An oncogenic role of sphingosine kinase. Curr Biol 10:1527-1530
22. Pitson SM, Moretti PA, Zebol J, Xia P, Gamble JR, Vadas MA, D'andrea RJ, Wattenberg BW 2000 Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase. J Biol Chem 275:33945-33950
23. Cuvillier O, Pirianov G, Kleuser B, Vanek PG, Coso OA, Gutkind S, Spiegel S 1996 Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature 381:800-803
24. Xia P, Wang L, Gamble JR, Vadas MA 1999 Activation of sphingosine kinase by tumor necrosis factor-α inhibits apoptosis in human endothelial cells. J Biol Chem 274:34499-34505
25. Gierthy JF, Lincoln DW, Roth KE, Bowser SS, Bennett JA, Bradley L, Dickerman HW 1991 Estrogen-stimulation of postconfluent cell accumulation and foci formation of human MCF-7 breast cancer cells. J Cell Biochem 45:177-187
26. Vladusic EA, Hornby AE, Guerra-Vladusic FK, Lakins J, Lupu R 2000 Expression and regulation of estrogen receptor β in human breast tumors and cell lines. Oncol Rep 7:157-167
27. Hyder SM, Chiappetta C, Murthy L, Stancel GM 1997 Selective inhibition of estrogen-regulated gene expression in vivo by the pure antiestrogen ICI 182,780. Cancer Res 57:2547-2549
28. Young KW, Nahorski SR 2001 Intracellular sphingosine 1-phosphate production: a novel pathway for Ca2+ release. Semin Cell Dev Biol 12:19-25
29. Mattie M, Brooker G, Spiegel S 1994 Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway. J Biol Chem 269:3181-3188
30. Choi OH, Kim JH, Kinet JP 1996 Calcium mobilization via sphingosine kinase in signalling by the Fc epsilon RI antigen receptor. Nature 380:634-636
31. Benten WP, Lieberherr M, Giese G, Wunderlich F 1998 Estradiol binding to cell surface raises cytosolic free calcium in T cells. FEBS Lett 422:349-353
32. Soulsby MD, Wojcikiewicz RJ 2002 2-Aminoethoxydiphenyl borate inhibits inositol 1,4,5-trisphosphate receptor function, ubiquitination and downregulation, but acts with variable characteristics in different cell types. Cell Calcium 32:175-181
33. Ghosh TK, Bian J, Gill DL 1994 Sphingosine 1-phosphate generated in the endoplasmic reticulum membrane activates release of stored calcium. J Biol Chem 269:22628-22635
34. Xia P, Gamble JR, Rye KA, Wang L, Hii CS, Cockerill P, Khew-Goodall Y, Bert AG, Barter PJ, Vadas MA 1998 Tumor necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway. Proc Natl Acad Sci USA 95:14196-14201
35. Razandi M, Pedram A, Greene GL, Levin ER 1999 Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERα and ERβ expressed in Chinese hamster ovary cells. Mol Endocrinol 13:307-319
36. Nava VE, Hobson JP, Murthy S, Milstien S, Spiegel S 2002 Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer MCF-7 cells. Exp Cell Res 281:115-127
37. Hla T, Lee MJ, Ancellin N, Paik JH, Kluk MJ 2001 Lysophospholipids - receptor revelations. Science 294:1875-1878
38. Wang F, Van Brocklyn JR, Edsall L, Nava VE, Spiegel S 1999 Sphingosine-1-phosphate inhibits motility of human breast cancer cells independently of cell surface receptors. Cancer Res 59:6185-6191
39. Ghosh TK, Bian J, Gill DL 1990 Intracellular calcium release mediated by sphingosine derivatives generated in cells. Science 248:1653-1656
40. Mathes C, Fleig A, Penner R 1998 Calcium release-activated calcium current (ICRAC) is a direct target for sphingosine. J Biol Chem 273:25020-25030
41. Migliaccio A, Piccolo D, Castoria G, Di Domenico M, Bilancio A, Lombardi M, Gong W, Beato M, Auricchio F 1998 Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor. EMBO J 17:2008-2018
42. Boonyaratanakornkit V, Scott MP, Ribon V, Sherman L, Anderson SM, Maller JL, Miller WT, Edwards DP 2001 Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases. Mol Cell 8:269-280
43. Rakhit S, Conway AM, Tate R, Bower T, Pyne NJ, Pyne S 1999 Sphingosine 1-phosphate stimulation of the p42/ p44 mitogen-activated protein kinase pathway in airway smooth muscle. Role of endothelial differentiation gene 1, c-Src tyrosine kinase and phosphoinositide 3-kinase. Biochem J 338:643-649
44. Shu X, Wu W, Mosteller RD, Broek D 2002 Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases. Mol Cell Biol 22:7758-7768
45. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450