Dual actions of sphingosine-1-phosphate: Extracellular through the G(i)- coupled receptor Edg-1 and intracellular to regulate proliferation and survival

Journal of Cell Biology

Volumn 142, Issue 1, 1998, Pages 229-240

  Van Brocklyn, James R ^a   Lee, Menq Jer ^b   Menzeleev, Ramil ^a   Olivera, Ana ^a   Edsall, Lisa ^a   Cuvillier, Olivier ^a   Thomas, Dianne M ^a   Coopman, Peter J P ^a   Thangada, Shobha ^b   Liu, Catherine H ^b   Hla, Timothy ^b   Spiegel, Sarah ^a,c  

^a GEORGETOWN UNIVERSITY   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^c GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

G proteins apoptosis; Mitogenesis; Signal transduction; Sphingolipids

Indexed keywords

CELL SURFACE RECEPTOR; SPHINGOSINE 1 PHOSPHATE;

ARTICLE; CELL PROLIFERATION; CELL PROTECTION; CELL SURFACE; CELL SURVIVAL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

3T3 CELLS; ANIMALS; CELL DIVISION; CELL LINE; CELL SURVIVAL; CYCLIC AMP; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HL-60 CELLS; HUMANS; IMMEDIATE-EARLY PROTEINS; LYSOPHOSPHOLIPIDS; MICE; PC12 CELLS; RATS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, LYSOPHOSPHOLIPID; SIGNAL TRANSDUCTION; SPHINGOSINE;

EID: 17344394207     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.142.1.229     Document Type: Article

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