-
1
-
-
0000293742
-
-
A. Alzheimer, Allg. Z. Psychiatr. Psych.-Gericht. Med. 64, 146 (1907); A. Pick, Monatschr. Psychiat. Neurol. 19, 97 (1906), F. H. Lewy, in Handbuch der Neurologie III (Springer-Verlag, Berlin, 1912), pp. 920-933.
-
(1907)
Allg. Z. Psychiatr. Psych.-Gericht. Med.
, vol.64
, pp. 146
-
-
Alzheimer, A.1
-
2
-
-
84940806954
-
-
A. Alzheimer, Allg. Z. Psychiatr. Psych.-Gericht. Med. 64, 146 (1907); A. Pick, Monatschr. Psychiat. Neurol. 19, 97 (1906), F. H. Lewy, in Handbuch der Neurologie III (Springer-Verlag, Berlin, 1912), pp. 920-933.
-
(1906)
Monatschr. Psychiat. Neurol.
, vol.19
, pp. 97
-
-
Pick, A.1
-
3
-
-
0001509014
-
-
Springer-Verlag, Berlin
-
A. Alzheimer, Allg. Z. Psychiatr. Psych.-Gericht. Med. 64, 146 (1907); A. Pick, Monatschr. Psychiat. Neurol. 19, 97 (1906), F. H. Lewy, in Handbuch der Neurologie III (Springer-Verlag, Berlin, 1912), pp. 920-933.
-
(1912)
Handbuch der Neurologie
, vol.3
, pp. 920-933
-
-
Lewy, F.H.1
-
4
-
-
0001239815
-
-
F. Nissl, Allg. Z. Psychiat. 48, 197 (1892); M. Bielchovsky, Neurol. Centralb. 22, 997 (1903).
-
(1892)
Allg. Z. Psychiat.
, vol.48
, pp. 197
-
-
Nissl, F.1
-
5
-
-
3643071986
-
-
F. Nissl, Allg. Z. Psychiat. 48, 197 (1892); M. Bielchovsky, Neurol. Centralb. 22, 997 (1903).
-
(1903)
Neurol. Centralb.
, vol.22
, pp. 997
-
-
Bielchovsky, M.1
-
6
-
-
0023147905
-
-
J. C. Mazziotta et al., N. Engl. J. Med. 316, 357 (1988); N. C. Fox and P. A. Freeborough, J. Magn. Reson. Imag. 7, 1069 (1997); E. M. Reiman et al., N. Engl. J. Med. 334, 752 (1996).
-
(1988)
N. Engl. J. Med.
, vol.316
, pp. 357
-
-
Mazziotta, J.C.1
-
7
-
-
0031397650
-
-
J. C. Mazziotta et al., N. Engl. J. Med. 316, 357 (1988); N. C. Fox and P. A. Freeborough, J. Magn. Reson. Imag. 7, 1069 (1997); E. M. Reiman et al., N. Engl. J. Med. 334, 752 (1996).
-
(1997)
J. Magn. Reson. Imag.
, vol.7
, pp. 1069
-
-
Fox, N.C.1
Freeborough, P.A.2
-
8
-
-
0029970342
-
-
J. C. Mazziotta et al., N. Engl. J. Med. 316, 357 (1988); N. C. Fox and P. A. Freeborough, J. Magn. Reson. Imag. 7, 1069 (1997); E. M. Reiman et al., N. Engl. J. Med. 334, 752 (1996).
-
(1996)
N. Engl. J. Med.
, vol.334
, pp. 752
-
-
Reiman, E.M.1
-
9
-
-
0021028244
-
-
J. F. Gusella et al., Nature 306, 234 (1983).
-
(1983)
Nature
, vol.306
, pp. 234
-
-
Gusella, J.F.1
-
10
-
-
0022005315
-
-
B. Oesch et al., Cell 40, 735 (1985); J. Kang et al., Nature 325, 733 (1987).
-
(1985)
Cell
, vol.40
, pp. 735
-
-
Oesch, B.1
-
11
-
-
0023105114
-
-
B. Oesch et al., Cell 40, 735 (1985); J. Kang et al., Nature 325, 733 (1987).
-
(1987)
Nature
, vol.325
, pp. 733
-
-
Kang, J.1
-
12
-
-
0024530897
-
-
F. Owen et al., Lancet i, 51 (1989); K. Hsiao et al., Nature 338, 342 (1989).
-
(1989)
Lancet
, vol.1
, pp. 51
-
-
Owen, F.1
-
13
-
-
0024519771
-
-
F. Owen et al., Lancet i, 51 (1989); K. Hsiao et al., Nature 338, 342 (1989).
-
(1989)
Nature
, vol.338
, pp. 342
-
-
Hsiao, K.1
-
14
-
-
0025800526
-
-
A. R. La Spada, E. M. Wilson, D. B. Lubahn, A. E. Harding, K. H. Fischbeck, Nature 352, 77 (1991); The Huntington's Disease Collaborative Research Group, Cell 72, 971 (1993).
-
(1991)
Nature
, vol.352
, pp. 77
-
-
La Spada, A.R.1
Wilson, E.M.2
Lubahn, D.B.3
Harding, A.E.4
Fischbeck, K.H.5
-
15
-
-
0027480960
-
-
A. R. La Spada, E. M. Wilson, D. B. Lubahn, A. E. Harding, K. H. Fischbeck, Nature 352, 77 (1991); The Huntington's Disease Collaborative Research Group, Cell 72, 971 (1993).
-
(1993)
Cell
, vol.72
, pp. 971
-
-
-
16
-
-
0025681138
-
-
K. K. Hsiao et al., Science 250, 1587 (1990).
-
(1990)
Science
, vol.250
, pp. 1587
-
-
Hsiao, K.K.1
-
17
-
-
18544410106
-
-
S. W. Davies et al., Cell 90, 537 (1997).
-
(1997)
Cell
, vol.90
, pp. 537
-
-
Davies, S.W.1
-
20
-
-
0025330687
-
-
J. Collinge et al., Lancet 336, 7 (1990), R. Medori et al., N. Engl. J. Med. 326, 444 (1992).
-
(1990)
Lancet
, vol.336
, pp. 7
-
-
Collinge, J.1
-
21
-
-
0026552043
-
-
J. Collinge et al., Lancet 336, 7 (1990), R. Medori et al., N. Engl. J. Med. 326, 444 (1992).
-
(1992)
N. Engl. J. Med.
, vol.326
, pp. 444
-
-
Medori, R.1
-
23
-
-
0027948959
-
-
T. Lynch et al., Neurology 44, 1878 (1994).
-
(1994)
Neurology
, vol.44
, pp. 1878
-
-
Lynch, T.1
-
24
-
-
0031949628
-
-
R. Crook et al., Nature Med. 4, 452 (1998); J. Kwok et al., Neuroreport 8, 1537 (1997).
-
(1998)
Nature Med.
, vol.4
, pp. 452
-
-
Crook, R.1
-
25
-
-
8244260610
-
-
R. Crook et al., Nature Med. 4, 452 (1998); J. Kwok et al., Neuroreport 8, 1537 (1997).
-
(1997)
Neuroreport
, vol.8
, pp. 1537
-
-
Kwok, J.1
-
26
-
-
0031949084
-
-
M. G. Spillantini, T. D. Bird, B. Ghetti, Brain Pathol. 8, 387 (1998); P. Poorkaj et al., Ann. Neurol. 43, 815 (1998); M. Hutton et al., Nature 393, 702 (1998); M. G. Spillantini et al., Proc. Natl. Acad. Sci. U.S.A. 95, 7737 (1998).
-
(1998)
Brain Pathol.
, vol.8
, pp. 387
-
-
Spillantini, M.G.1
Bird, T.D.2
Ghetti, B.3
-
27
-
-
14444284106
-
-
M. G. Spillantini, T. D. Bird, B. Ghetti, Brain Pathol. 8, 387 (1998); P. Poorkaj et al., Ann. Neurol. 43, 815 (1998); M. Hutton et al., Nature 393, 702 (1998); M. G. Spillantini et al., Proc. Natl. Acad. Sci. U.S.A. 95, 7737 (1998).
-
(1998)
Ann. Neurol.
, vol.43
, pp. 815
-
-
Poorkaj, P.1
-
28
-
-
0032543684
-
-
M. G. Spillantini, T. D. Bird, B. Ghetti, Brain Pathol. 8, 387 (1998); P. Poorkaj et al., Ann. Neurol. 43, 815 (1998); M. Hutton et al., Nature 393, 702 (1998); M. G. Spillantini et al., Proc. Natl. Acad. Sci. U.S.A. 95, 7737 (1998).
-
(1998)
Nature
, vol.393
, pp. 702
-
-
Hutton, M.1
-
29
-
-
0032560487
-
-
M. G. Spillantini, T. D. Bird, B. Ghetti, Brain Pathol. 8, 387 (1998); P. Poorkaj et al., Ann. Neurol. 43, 815 (1998); M. Hutton et al., Nature 393, 702 (1998); M. G. Spillantini et al., Proc. Natl. Acad. Sci. U.S.A. 95, 7737 (1998).
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 7737
-
-
Spillantini, M.G.1
-
30
-
-
0026496257
-
-
L. G. Goldfarb et al., Science 258, 806 (1992); H. F. Baker et al., Lancet 337, 1286 (1991).
-
(1992)
Science
, vol.258
, pp. 806
-
-
Goldfarb, L.G.1
-
31
-
-
0025865455
-
-
L. G. Goldfarb et al., Science 258, 806 (1992); H. F. Baker et al., Lancet 337, 1286 (1991).
-
(1991)
Lancet
, vol.337
, pp. 1286
-
-
Baker, H.F.1
-
32
-
-
0027194791
-
-
E. H. Corder et al., Science 261, 921 (1993).
-
(1993)
Science
, vol.261
, pp. 921
-
-
Corder, E.H.1
-
33
-
-
0001026258
-
-
H. Houlden et al., Lancet 342, 737 (1993);
-
(1993)
Lancet
, vol.342
, pp. 737
-
-
Houlden, H.1
-
37
-
-
0025964041
-
-
B. Pakkenberg, A. Moller, H. J. Gundersen, A. Mauritzen Dam, H. Pakkenberg, J. Neurol. Neurosurg. Psychiatr. 54, 30 (1991).
-
(1991)
J. Neurol. Neurosurg. Psychiatr.
, vol.54
, pp. 30
-
-
Pakkenberg, B.1
Moller, A.2
Gundersen, H.J.3
Mauritzen Dam, A.4
Pakkenberg, H.5
-
38
-
-
0029048831
-
-
C. S. Lee et al., Neurology 45, 435 (1995).
-
(1995)
Neurology
, vol.45
, pp. 435
-
-
Lee, C.S.1
-
39
-
-
0028972448
-
-
Y. Trottier et al., Nature 378, 403 (1995);
-
(1995)
Nature
, vol.378
, pp. 403
-
-
Trottier, Y.1
-
43
-
-
0027401203
-
-
D. R. Rosen et al., Nature 362, 59 (1993).
-
(1993)
Nature
, vol.362
, pp. 59
-
-
Rosen, D.R.1
-
44
-
-
0025800165
-
-
E. J. Kremer et al., Science 252, 1711 (1991).
-
(1991)
Science
, vol.252
, pp. 1711
-
-
Kremer, E.J.1
-
45
-
-
0026603841
-
-
M. Mahadevan et al., ibid. 255, 1253 (1992); J. Buxton et al., Nature 355, 547 (1992).
-
(1992)
Science
, vol.255
, pp. 1253
-
-
Mahadevan, M.1
-
46
-
-
0026584805
-
-
M. Mahadevan et al., ibid. 255, 1253 (1992); J. Buxton et al., Nature 355, 547 (1992).
-
(1992)
Nature
, vol.355
, pp. 547
-
-
Buxton, J.1
-
47
-
-
13344270899
-
-
V. Campuzano et al., Science 271, 1423 (1996).
-
(1996)
Science
, vol.271
, pp. 1423
-
-
Campuzano, V.1
-
48
-
-
0032501740
-
-
S. W. Davies et al., Lancet 351, 131 (1998).
-
(1998)
Lancet
, vol.351
, pp. 131
-
-
Davies, S.W.1
-
49
-
-
0004196886
-
-
Arnold, London, ed. 6
-
D. I. Graham and P. L. Lantos, Eds., Greenfield's Neuropathology (Arnold, London, ed. 6, 1997); J. S. Steele, Brain 95, 693 (1972), V. Buee-Scherrer et al., Am. J. Pathol. 146, 924 (1995); S. Dlouhy et al., Nature Genet. 1, 64 (1992).
-
(1997)
Greenfield's Neuropathology
-
-
Graham, D.I.1
Lantos, P.L.2
-
50
-
-
0015463054
-
-
D. I. Graham and P. L. Lantos, Eds., Greenfield's Neuropathology (Arnold, London, ed. 6, 1997); J. S. Steele, Brain 95, 693 (1972), V. Buee-Scherrer et al., Am. J. Pathol. 146, 924 (1995); S. Dlouhy et al., Nature Genet. 1, 64 (1992).
-
(1972)
Brain
, vol.95
, pp. 693
-
-
Steele, J.S.1
-
51
-
-
0028957084
-
-
D. I. Graham and P. L. Lantos, Eds., Greenfield's Neuropathology (Arnold, London, ed. 6, 1997); J. S. Steele, Brain 95, 693 (1972), V. Buee-Scherrer et al., Am. J. Pathol. 146, 924 (1995); S. Dlouhy et al., Nature Genet. 1, 64 (1992).
-
(1995)
Am. J. Pathol.
, vol.146
, pp. 924
-
-
Buee-Scherrer, V.1
-
52
-
-
0026849545
-
-
D. I. Graham and P. L. Lantos, Eds., Greenfield's Neuropathology (Arnold, London, ed. 6, 1997); J. S. Steele, Brain 95, 693 (1972), V. Buee-Scherrer et al., Am. J. Pathol. 146, 924 (1995); S. Dlouhy et al., Nature Genet. 1, 64 (1992).
-
(1992)
Nature Genet.
, vol.1
, pp. 64
-
-
Dlouhy, S.1
-
53
-
-
0006164301
-
-
I. G. McKeith et al., Neurology 47, 1113 (1996); P. L. Lantos et al., Neurosci. Lett. 172, 77 (1992); P. Piccardo et al., Neurobiol. Aging 19, S172 (1998).
-
(1996)
Neurology
, vol.47
, pp. 1113
-
-
McKeith, I.G.1
-
54
-
-
0006164301
-
-
I. G. McKeith et al., Neurology 47, 1113 (1996); P. L. Lantos et al., Neurosci. Lett. 172, 77 (1992); P. Piccardo et al., Neurobiol. Aging 19, S172 (1998).
-
(1992)
Neurosci. Lett.
, vol.172
, pp. 77
-
-
Lantos, P.L.1
-
55
-
-
0006164301
-
-
I. G. McKeith et al., Neurology 47, 1113 (1996); P. L. Lantos et al., Neurosci. Lett. 172, 77 (1992); P. Piccardo et al., Neurobiol. Aging 19, S172 (1998).
-
(1998)
Neurobiol. Aging
, vol.19
-
-
Piccardo, P.1
-
56
-
-
0029062956
-
-
M. B. Feany and D. W. Dickson, Am. J. Pathol. 146, 1388 (1995); T. Iwatsubo, M. Hasegawa, Y. Ihara, Acta Neuropathol. 88, 129 (1994); K. Ikeda et al., Neurosci. Lett. 174, 157 (1994); T. Yamada, P. L. McGeer, E. G. McGeer, ibid. 135, 99 (1992).
-
(1995)
Am. J. Pathol.
, vol.146
, pp. 1388
-
-
Feany, M.B.1
Dickson, D.W.2
-
57
-
-
0027978991
-
-
M. B. Feany and D. W. Dickson, Am. J. Pathol. 146, 1388 (1995); T. Iwatsubo, M. Hasegawa, Y. Ihara, Acta Neuropathol. 88, 129 (1994); K. Ikeda et al., Neurosci. Lett. 174, 157 (1994); T. Yamada, P. L. McGeer, E. G. McGeer, ibid. 135, 99 (1992).
-
(1994)
Acta Neuropathol.
, vol.88
, pp. 129
-
-
Iwatsubo, T.1
Hasegawa, M.2
Ihara, Y.3
-
58
-
-
0028305261
-
-
M. B. Feany and D. W. Dickson, Am. J. Pathol. 146, 1388 (1995); T. Iwatsubo, M. Hasegawa, Y. Ihara, Acta Neuropathol. 88, 129 (1994); K. Ikeda et al., Neurosci. Lett. 174, 157 (1994); T. Yamada, P. L. McGeer, E. G. McGeer, ibid. 135, 99 (1992).
-
(1994)
Neurosci. Lett.
, vol.174
, pp. 157
-
-
Ikeda, K.1
-
59
-
-
0026543843
-
-
M. B. Feany and D. W. Dickson, Am. J. Pathol. 146, 1388 (1995); T. Iwatsubo, M. Hasegawa, Y. Ihara, Acta Neuropathol. 88, 129 (1994); K. Ikeda et al., Neurosci. Lett. 174, 157 (1994); T. Yamada, P. L. McGeer, E. G. McGeer, ibid. 135, 99 (1992).
-
(1992)
Neurosci. Lett.
, vol.135
, pp. 99
-
-
Yamada, T.1
McGeer, P.L.2
McGeer, E.G.3
-
61
-
-
0020517951
-
-
J. E. Goldman, S. H. Yen, F. C. Chiu, N. S. Peress, ibid. 221, 1082 (1983); M. G. Spillantini et al., Proc. Natl. Acad. Sci. U.S.A. 95, 6469 (1998); V. L. Buchman et al., Nature Neurosci. 1, 101 (1998).
-
(1983)
Science
, vol.221
, pp. 1082
-
-
Goldman, J.E.1
Yen, S.H.2
Chiu, F.C.3
Peress, N.S.4
-
62
-
-
0032568534
-
-
J. E. Goldman, S. H. Yen, F. C. Chiu, N. S. Peress, ibid. 221, 1082 (1983); M. G. Spillantini et al., Proc. Natl. Acad. Sci. U.S.A. 95, 6469 (1998); V. L. Buchman et al., Nature Neurosci. 1, 101 (1998).
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 6469
-
-
Spillantini, M.G.1
-
63
-
-
0032083048
-
-
J. E. Goldman, S. H. Yen, F. C. Chiu, N. S. Peress, ibid. 221, 1082 (1983); M. G. Spillantini et al., Proc. Natl. Acad. Sci. U.S.A. 95, 6469 (1998); V. L. Buchman et al., Nature Neurosci. 1, 101 (1998).
-
(1998)
Nature Neurosci.
, vol.1
, pp. 101
-
-
Buchman, V.L.1
-
64
-
-
84920314905
-
-
I. Shoulson, Science 282, 1071 (1998).
-
(1998)
Science
, vol.282
, pp. 1071
-
-
Shoulson, I.1
-
65
-
-
0024530897
-
-
F. Owen et al., Lancet i, 51 (1989); K. Hsiao et al., Nature 338, 342 (1989); K. Hsiao et al., Science 250, 1587 (1990); K. Hsiao et al., Nature Genet. 1, 68 (1992).
-
(1989)
Lancet
, vol.1
, pp. 51
-
-
Owen, F.1
-
66
-
-
0024519771
-
-
F. Owen et al., Lancet i, 51 (1989); K. Hsiao et al., Nature 338, 342 (1989); K. Hsiao et al., Science 250, 1587 (1990); K. Hsiao et al., Nature Genet. 1, 68 (1992).
-
(1989)
Nature
, vol.338
, pp. 342
-
-
Hsiao, K.1
-
67
-
-
0025681138
-
-
F. Owen et al., Lancet i, 51 (1989); K. Hsiao et al., Nature 338, 342 (1989); K. Hsiao et al., Science 250, 1587 (1990); K. Hsiao et al., Nature Genet. 1, 68 (1992).
-
(1990)
Science
, vol.250
, pp. 1587
-
-
Hsiao, K.1
-
68
-
-
0026849947
-
-
F. Owen et al., Lancet i, 51 (1989); K. Hsiao et al., Nature 338, 342 (1989); K. Hsiao et al., Science 250, 1587 (1990); K. Hsiao et al., Nature Genet. 1, 68 (1992).
-
(1992)
Nature Genet.
, vol.1
, pp. 68
-
-
Hsiao, K.1
-
69
-
-
0026088977
-
-
A. M. Goate et al., Nature 349, 704 (1991), D. Games et al., ibid. 373, 523 (1995); N. Suzuki et al., Science 264, 1336 (1994)
-
(1991)
Nature
, vol.349
, pp. 704
-
-
Goate, A.M.1
-
70
-
-
0028985574
-
-
A. M. Goate et al., Nature 349, 704 (1991), D. Games et al., ibid. 373, 523 (1995); N. Suzuki et al., Science 264, 1336 (1994)
-
(1995)
Nature
, vol.373
, pp. 523
-
-
Games, D.1
-
71
-
-
0028322017
-
-
A. M. Goate et al., Nature 349, 704 (1991), D. Games et al., ibid. 373, 523 (1995); N. Suzuki et al., Science 264, 1336 (1994)
-
(1994)
Science
, vol.264
, pp. 1336
-
-
Suzuki, N.1
-
72
-
-
0029004341
-
-
R. Sherrington et al., Nature 375, 754 (1995); D. Scheuner et al., Nature Med. 2, 864 (1996); K. Duff et al., Nature 383, 710 (1996); D. Borchelt et al., Neuron 17, 1005 (1996); M. Citron et al., Nature Med. 3, 67 (1997); L. Holcomb et al., ibid. 4, 97 (1998).
-
(1995)
Nature
, vol.375
, pp. 754
-
-
Sherrington, R.1
-
73
-
-
16044373524
-
-
R. Sherrington et al., Nature 375, 754 (1995); D. Scheuner et al., Nature Med. 2, 864 (1996); K. Duff et al., Nature 383, 710 (1996); D. Borchelt et al., Neuron 17, 1005 (1996); M. Citron et al., Nature Med. 3, 67 (1997); L. Holcomb et al., ibid. 4, 97 (1998).
-
(1996)
Nature Med.
, vol.2
, pp. 864
-
-
Scheuner, D.1
-
74
-
-
16044366039
-
-
R. Sherrington et al., Nature 375, 754 (1995); D. Scheuner et al., Nature Med. 2, 864 (1996); K. Duff et al., Nature 383, 710 (1996); D. Borchelt et al., Neuron 17, 1005 (1996); M. Citron et al., Nature Med. 3, 67 (1997); L. Holcomb et al., ibid. 4, 97 (1998).
-
(1996)
Nature
, vol.383
, pp. 710
-
-
Duff, K.1
-
75
-
-
0030293676
-
-
R. Sherrington et al., Nature 375, 754 (1995); D. Scheuner et al., Nature Med. 2, 864 (1996); K. Duff et al., Nature 383, 710 (1996); D. Borchelt et al., Neuron 17, 1005 (1996); M. Citron et al., Nature Med. 3, 67 (1997); L. Holcomb et al., ibid. 4, 97 (1998).
-
(1996)
Neuron
, vol.17
, pp. 1005
-
-
Borchelt, D.1
-
76
-
-
16944362157
-
-
R. Sherrington et al., Nature 375, 754 (1995); D. Scheuner et al., Nature Med. 2, 864 (1996); K. Duff et al., Nature 383, 710 (1996); D. Borchelt et al., Neuron 17, 1005 (1996); M. Citron et al., Nature Med. 3, 67 (1997); L. Holcomb et al., ibid. 4, 97 (1998).
-
(1997)
Nature Med.
, vol.3
, pp. 67
-
-
Citron, M.1
-
77
-
-
0031914718
-
-
R. Sherrington et al., Nature 375, 754 (1995); D. Scheuner et al., Nature Med. 2, 864 (1996); K. Duff et al., Nature 383, 710 (1996); D. Borchelt et al., Neuron 17, 1005 (1996); M. Citron et al., Nature Med. 3, 67 (1997); L. Holcomb et al., ibid. 4, 97 (1998).
-
(1998)
Nature Med.
, vol.4
, pp. 97
-
-
Holcomb, L.1
-
78
-
-
0029087026
-
-
E. Levey-Lahad et al., Science 269, 973 (1995); D. Scheuner et al., Nature Med. 2, 864 (1996); F. Oyama et al., J Neurochem. 71, 313 (1998).
-
(1995)
Science
, vol.269
, pp. 973
-
-
Levey-Lahad, E.1
-
79
-
-
16044373524
-
-
E. Levey-Lahad et al., Science 269, 973 (1995); D. Scheuner et al., Nature Med. 2, 864 (1996); F. Oyama et al., J Neurochem. 71, 313 (1998).
-
(1996)
Nature Med.
, vol.2
, pp. 864
-
-
Scheuner, D.1
-
80
-
-
18544411933
-
-
E. Levey-Lahad et al., Science 269, 973 (1995); D. Scheuner et al., Nature Med. 2, 864 (1996); F. Oyama et al., J Neurochem. 71, 313 (1998).
-
(1998)
J Neurochem.
, vol.71
, pp. 313
-
-
Oyama, F.1
-
84
-
-
0027401203
-
-
D. R. Rosen et al., Nature 362, 59 (1993); M. E. Gurney et al., Science 264, 1772 (1994); N. Shibata et al., J. Neuropathol. Exp. Neurol. 55, 481 (1996).
-
(1993)
Nature
, vol.362
, pp. 59
-
-
Rosen, D.R.1
-
85
-
-
0028284779
-
-
D. R. Rosen et al., Nature 362, 59 (1993); M. E. Gurney et al., Science 264, 1772 (1994); N. Shibata et al., J. Neuropathol. Exp. Neurol. 55, 481 (1996).
-
(1994)
Science
, vol.264
, pp. 1772
-
-
Gurney, M.E.1
-
86
-
-
0029927679
-
-
D. R. Rosen et al., Nature 362, 59 (1993); M. E. Gurney et al., Science 264, 1772 (1994); N. Shibata et al., J. Neuropathol. Exp. Neurol. 55, 481 (1996).
-
(1996)
J. Neuropathol. Exp. Neurol.
, vol.55
, pp. 481
-
-
Shibata, N.1
-
87
-
-
0025800526
-
-
A. R. La Spada et al., Nature 352, 77 (1991); A. Abdullah et al., Hum. Mol. Genet. 7, 379 (1998); P. M. Bingham et al., Nature Genet. 9, 191 (1995); M. Li et al., Ann. Neurol. 44, 249 (1998).
-
(1991)
Nature
, vol.352
, pp. 77
-
-
La Spada, A.R.1
-
88
-
-
0031934542
-
-
A. R. La Spada et al., Nature 352, 77 (1991); A. Abdullah et al., Hum. Mol. Genet. 7, 379 (1998); P. M. Bingham et al., Nature Genet. 9, 191 (1995); M. Li et al., Ann. Neurol. 44, 249 (1998).
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 379
-
-
Abdullah, A.1
-
89
-
-
0028878844
-
-
A. R. La Spada et al., Nature 352, 77 (1991); A. Abdullah et al., Hum. Mol. Genet. 7, 379 (1998); P. M. Bingham et al., Nature Genet. 9, 191 (1995); M. Li et al., Ann. Neurol. 44, 249 (1998).
-
(1995)
Nature Genet.
, vol.9
, pp. 191
-
-
Bingham, P.M.1
-
90
-
-
15144342225
-
-
A. R. La Spada et al., Nature 352, 77 (1991); A. Abdullah et al., Hum. Mol. Genet. 7, 379 (1998); P. M. Bingham et al., Nature Genet. 9, 191 (1995); M. Li et al., Ann. Neurol. 44, 249 (1998).
-
(1998)
Ann. Neurol.
, vol.44
, pp. 249
-
-
Li, M.1
-
91
-
-
0027480960
-
-
The Huntington's Disease Collaborative Research Group, Cell 72, 971 (1993); S. W. Davies et al., ibid. 90, 537 (1997); E. Scherzing et al., ibid., p. 549.
-
(1993)
Cell
, vol.72
, pp. 971
-
-
-
92
-
-
18544410106
-
-
The Huntington's Disease Collaborative Research Group, Cell 72, 971 (1993); S. W. Davies et al., ibid. 90, 537 (1997); E. Scherzing et al., ibid., p. 549.
-
(1997)
Cell
, vol.90
, pp. 537
-
-
Davies, S.W.1
-
93
-
-
0027480960
-
-
The Huntington's Disease Collaborative Research Group, Cell 72, 971 (1993); S. W. Davies et al., ibid. 90, 537 (1997); E. Scherzing et al., ibid., p. 549.
-
Cell
, pp. 549
-
-
Scherzing, E.1
-
94
-
-
0028216760
-
-
R. Koide et al., Nature Genet. 6, 9 (1998); S. Nagafuchi et al., ibid., p. 14; M. W. Becher et al., Neurobiol. Dis. 4, 387 (1998).
-
(1998)
Nature Genet.
, vol.6
, pp. 9
-
-
Koide, R.1
-
95
-
-
0028216760
-
-
R. Koide et al., Nature Genet. 6, 9 (1998); S. Nagafuchi et al., ibid., p. 14; M. W. Becher et al., Neurobiol. Dis. 4, 387 (1998).
-
Nature Genet.
, pp. 14
-
-
Nagafuchi, S.1
-
96
-
-
0031918640
-
-
R. Koide et al., Nature Genet. 6, 9 (1998); S. Nagafuchi et al., ibid., p. 14; M. W. Becher et al., Neurobiol. Dis. 4, 387 (1998).
-
(1998)
Neurobiol. Dis.
, vol.4
, pp. 387
-
-
Becher, M.W.1
-
97
-
-
0027164698
-
-
H. T. Orr et al., Nature Genet. 4, 221 (1993); E. N. Burright et al., Cell 82, 937 (1995); P. J. Skinner et al., Nature 389, 971 (1997); H. B. Clark et al., J. Neurosci. 17, 7385 (1997).
-
(1993)
Nature Genet.
, vol.4
, pp. 221
-
-
Orr, H.T.1
-
98
-
-
0029163222
-
-
H. T. Orr et al., Nature Genet. 4, 221 (1993); E. N. Burright et al., Cell 82, 937 (1995); P. J. Skinner et al., Nature 389, 971 (1997); H. B. Clark et al., J. Neurosci. 17, 7385 (1997).
-
(1995)
Cell
, vol.82
, pp. 937
-
-
Burright, E.N.1
-
99
-
-
0030666001
-
-
H. T. Orr et al., Nature Genet. 4, 221 (1993); E. N. Burright et al., Cell 82, 937 (1995); P. J. Skinner et al., Nature 389, 971 (1997); H. B. Clark et al., J. Neurosci. 17, 7385 (1997).
-
(1997)
Nature
, vol.389
, pp. 971
-
-
Skinner, P.J.1
-
100
-
-
0030864463
-
-
H. T. Orr et al., Nature Genet. 4, 221 (1993); E. N. Burright et al., Cell 82, 937 (1995); P. J. Skinner et al., Nature 389, 971 (1997); H. B. Clark et al., J. Neurosci. 17, 7385 (1997).
-
(1997)
J. Neurosci.
, vol.17
, pp. 7385
-
-
Clark, H.B.1
-
102
-
-
0028143527
-
-
Y. Kawaguchi et al., ibid. 8, 221 (1994); H. Ikeda et al., ibid. 13, 196 (1996); H. L. Paulson et al., Neuron 19, 333 (1997).
-
(1994)
Nature Genet.
, vol.8
, pp. 221
-
-
Kawaguchi, Y.1
-
103
-
-
0030058208
-
-
Y. Kawaguchi et al., ibid. 8, 221 (1994); H. Ikeda et al., ibid. 13, 196 (1996); H. L. Paulson et al., Neuron 19, 333 (1997).
-
(1996)
Nature Genet.
, vol.13
, pp. 196
-
-
Ikeda, H.1
-
104
-
-
0030850412
-
-
Y. Kawaguchi et al., ibid. 8, 221 (1994); H. Ikeda et al., ibid. 13, 196 (1996); H. L. Paulson et al., Neuron 19, 333 (1997).
-
(1997)
Neuron
, vol.19
, pp. 333
-
-
Paulson, H.L.1
-
106
-
-
0028020605
-
-
L. P. Ranum, L. J Schut, J. K. Lundgren, H. T. Orr, D. M. Livingston, Nature Genet. 8, 280 (1994).
-
(1994)
Nature Genet.
, vol.8
, pp. 280
-
-
Ranum, L.P.1
Schut, L.J.2
Lundgren, J.K.3
Orr, H.T.4
Livingston, D.M.5
-
107
-
-
0031012399
-
-
The polyglutamine expansions in SCA6 are more modest than in other polyglutamine diseases and occur in the α1A voltage-dependent calcium channel. It is not yet clear whether the pathogenesis in this disease relates to polyglutamine inclusions or to dysfunction of the ion channel [O. Zhuchenko et al., Nature Genet. 15, 62 (1997)].
-
(1997)
Nature Genet.
, vol.15
, pp. 62
-
-
Zhuchenko, O.1
-
108
-
-
16944364511
-
-
G. David et al., Nature Genet. 17, 65 (1997); M. Holberg et al., Hum. Mol. Genet. 7, 913 (1998).
-
(1997)
Nature Genet.
, vol.17
, pp. 65
-
-
David, G.1
-
109
-
-
7144229376
-
-
G. David et al., Nature Genet. 17, 65 (1997); M. Holberg et al., Hum. Mol. Genet. 7, 913 (1998).
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 913
-
-
Holberg, M.1
-
110
-
-
84920310997
-
-
note
-
We thank D. Dickson for his help and encouragement and for the figures. Work in the authors' laboratory was funded by the NIA (Mayo/USF Program Project grant) and by the Mayo Foundation.
-
-
-
|