-
2
-
-
0027729733
-
-
Cleland, J. L.; Powell, M. F.; Shire, S. J. Crit. Rev. Ther. Drug Carrier Syst. 1993, 10, 307-377.
-
(1993)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.10
, pp. 307-377
-
-
Cleland, J.L.1
Powell, M.F.2
Shire, S.J.3
-
4
-
-
0001573172
-
-
Rey, L., May, J. C., Eds.; Marcel Dekker: New York
-
Pikal, M. J. In Freeze-Drying/Lyophilization of Pharmaceutical and Biological Products; Rey, L., May, J. C., Eds.; Marcel Dekker: New York, 1999; pp 161-198.
-
(1999)
Freeze-Drying/Lyophilization of Pharmaceutical and Biological Products
, pp. 161-198
-
-
Pikal, M.J.1
-
5
-
-
0039723136
-
-
Remmele, R. L., Jr., Bhat, S. D.; Phan, D. H.; Gombotz, W. R. Biochemistry 1999, 38, 5241-5247.
-
(1999)
Biochemistry
, vol.38
, pp. 5241-5247
-
-
Remmele R.L., Jr.1
Bhat, S.D.2
Phan, D.H.3
Gombotz, W.R.4
-
6
-
-
0035895368
-
-
Grillo, A. O.; Edwards, K.-L. T.; Kashi, R. S.; Shipley, K. M.; Hu, L.; Besman, M. J.; Middaugh, C. R. Biochemistry 2001, 40, 586.
-
(2001)
Biochemistry
, vol.40
, pp. 586
-
-
Grillo, A.O.1
Edwards, K.-L.T.2
Kashi, R.S.3
Shipley, K.M.4
Hu, L.5
Besman, M.J.6
Middaugh, C.R.7
-
7
-
-
0032564420
-
-
Kendrick, B. S.; Carpenter, J. F.; Cleland, J. L.; Randolph, T. W. Proc. Natl. Acad. Sci. U.S.A. 1998, 95, 14142.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 14142
-
-
Kendrick, B.S.1
Carpenter, J.F.2
Cleland, J.L.3
Randolph, T.W.4
-
8
-
-
0034711745
-
-
Finke, J. M.; Roy, M.; Zimm, B. H.; Jennings, P. A. Biochemistry 2000, 39, 575-583.
-
(2000)
Biochemistry
, vol.39
, pp. 575-583
-
-
Finke, J.M.1
Roy, M.2
Zimm, B.H.3
Jennings, P.A.4
-
11
-
-
0000295322
-
-
Verheul, M.; Roefs, S. P. F. M.; de Kruif, K. G. J. Agric. Food Chem. 1998, 46, 896-903.
-
(1998)
J. Agric. Food Chem.
, vol.46
, pp. 896-903
-
-
Verheul, M.1
Roefs, S.P.F.M.2
De Kruif, K.G.3
-
12
-
-
0033526550
-
-
Foguel, D.; Robinson, C. R.; de Sousa, P. C., Jr.; Silva, J. L.; Robinson, A. S. Biotechnol. Bioeng. 1999, 63, 552-558.
-
(1999)
Biotechnol. Bioeng.
, vol.63
, pp. 552-558
-
-
Foguel, D.1
Robinson, C.R.2
De Sousa P.C., Jr.3
Silva, J.L.4
Robinson, A.S.5
-
13
-
-
0030778239
-
-
Shi, P.-Y.; Maizels, N.; Weiner, A. M. BioTechniques 1997, 23, 1036-1038.
-
(1997)
BioTechniques
, vol.23
, pp. 1036-1038
-
-
Shi, P.-Y.1
Maizels, N.2
Weiner, A.M.3
-
15
-
-
0034695564
-
-
Kim, Y.-S.; Wall, J. S.; Meyer, J.; Murphy, C.; Randolph, T. W.; Manning, M. C.; Solomon, A.; Carpenter, J. F. J. Biol. Chem. 2000, 275, 1570-1574.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 1570-1574
-
-
Kim, Y.-S.1
Wall, J.S.2
Meyer, J.3
Murphy, C.4
Randolph, T.W.5
Manning, M.C.6
Solomon, A.7
Carpenter, J.F.8
-
16
-
-
0033538541
-
-
Wood, S. J.; Wypych, J.; Steavenson, S.; Louis, J.-C.; Citron, M.; Biere, A. L. J. Biol. Chem. 1999, 274, 19509-19512.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19509-19512
-
-
Wood, S.J.1
Wypych, J.2
Steavenson, S.3
Louis, J.-C.4
Citron, M.5
Biere, A.L.6
-
17
-
-
0030024717
-
-
Esler, W. P.; Stimson, E. R.; Ghilardi, J. R.; Vinters, H. V.; Lee, J. P.; Mantyh, P. W.; Maggio, J. E. Biochemistry 1996, 35, 749-757.
-
(1996)
Biochemistry
, vol.35
, pp. 749-757
-
-
Esler, W.P.1
Stimson, E.R.2
Ghilardi, J.R.3
Vinters, H.V.4
Lee, J.P.5
Mantyh, P.W.6
Maggio, J.E.7
-
18
-
-
0035918550
-
-
Nielsen, L.; Khurana, R.; Coats, A.; Frokjaer, S.; Brange, J.; Vyas. S.; Uversky, V.; Fink, A. L. Biochemistry 2001, 40, 6036-6046.
-
(2001)
Biochemistry
, vol.40
, pp. 6036-6046
-
-
Nielsen, L.1
Khurana, R.2
Coats, A.3
Frokjaer, S.4
Brange, J.5
Vyas, S.6
Uversky, V.7
Fink, A.L.8
-
20
-
-
0030846441
-
-
Lomakin, A.; Teplow, D. B.; Kirschner, D. A.; Benedek, G. B. Proc. Natl. Acad. Sci. U.S.A. 1997, 94, 7942-7947.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 7942-7947
-
-
Lomakin, A.1
Teplow, D.B.2
Kirschner, D.A.3
Benedek, G.B.4
-
21
-
-
0028073866
-
-
Yoshioka, S.; Aso, Y.; Isutsu, K.-I.; Kojima, S. Pharm. Res. 1994, 11, 1721-1725.
-
(1994)
Pharm. Res.
, vol.11
, pp. 1721-1725
-
-
Yoshioka, S.1
Aso, Y.2
Isutsu, K.-I.3
Kojima, S.4
-
22
-
-
0034237295
-
-
Plaza del Pino, I. M.; Ibarra-Molero, B.; Sanchez-Ruiz, J. M. Proteins: Struct., Funct., Genet. 2000, 40, 58.
-
(2000)
Proteins: Struct., Funct., Genet.
, vol.40
, pp. 58
-
-
Plaza Del Pino, I.M.1
Ibarra-Molero, B.2
Sanchez-Ruiz, J.M.3
-
24
-
-
0003007528
-
-
Ahern, T. J., Manning, M. C., Eds.; Plenum Press: New York
-
Zaks, A. In Stability of Protein Pharmaceuticals; Ahern, T. J., Manning, M. C., Eds.; Plenum Press: New York, 1992; pp 249-272.
-
(1992)
Stability of Protein Pharmaceuticals
, pp. 249-272
-
-
Zaks, A.1
-
25
-
-
0027995384
-
-
Fink, A. L.; Calciano, L. J.; Goto, Y.; Kurotsu, T.; Palleros, D. R. Biochemistry 1994, 33, 12504-12511.
-
(1994)
Biochemistry
, vol.33
, pp. 12504-12511
-
-
Fink, A.L.1
Calciano, L.J.2
Goto, Y.3
Kurotsu, T.4
Palleros, D.R.5
-
26
-
-
0034082815
-
-
Petsev, D. N.; Thomas, B. R.; Yau, S.-T.; Vekilov, P. G. Biophys. J. 2000, 78, 2060-2069.
-
(2000)
Biophys. J.
, vol.78
, pp. 2060-2069
-
-
Petsev, D.N.1
Thomas, B.R.2
Yau, S.-T.3
Vekilov, P.G.4
-
27
-
-
0035797795
-
-
Kheterpal, I.; Williams, A.; Murphy, C.; Bledsoe, B.; Wetzel, R. Biochemistry 2001, 40, 11757-11767.
-
(2001)
Biochemistry
, vol.40
, pp. 11757-11767
-
-
Kheterpal, I.1
Williams, A.2
Murphy, C.3
Bledsoe, B.4
Wetzel, R.5
-
28
-
-
0032731353
-
-
Hammarstrom, P.; Persson, M.; Freskgard, P.-O.; Martensson, L.-G.; Andersson, D.; Jonsson, B.-H.; Carlsson, U. J. Biol. Chem. 1999, 274, 32897-32903.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32897-32903
-
-
Hammarstrom, P.1
Persson, M.2
Freskgard, P.-O.3
Martensson, L.-G.4
Andersson, D.5
Jonsson, B.-H.6
Carlsson, U.7
-
29
-
-
0033596963
-
-
Smellar, L.; Rubens, P.; Heremans, K. Biochemistry 1999, 38, 3816-3820.
-
(1999)
Biochemistry
, vol.38
, pp. 3816-3820
-
-
Smellar, L.1
Rubens, P.2
Heremans, K.3
-
30
-
-
0033515471
-
-
Narhi, L.; Wood; S. J.; Steavenson; S.; Jiang, Y.; Wu, G. M.; Anafi, D.; Kaufman, S. A.; Martin, F.; Sitney, K.; Denis, P.; Louis, J.-C.; Wypych, J.; Biere, A. L.; Citron, M. J. Biol. Chem. 1999, 14, 9843-9846.
-
(1999)
J. Biol. Chem.
, vol.14
, pp. 9843-9846
-
-
Narhi, L.1
Wood, S.J.2
Steavenson, S.3
Jiang, Y.4
Wu, G.M.5
Anafi, D.6
Kaufman, S.A.7
Martin, F.8
Sitney, K.9
Denis, P.10
Louis, J.-C.11
Wypych, J.12
Biere, A.L.13
Citron, M.14
-
31
-
-
0032559003
-
-
Naiki, H.; Hasegawa, K.; Yamaguchi, I.; Nakamura, H.; Gejyo, F.; Nakakuki, K. Biochemistry 1998, 37, 17882-17889.
-
(1998)
Biochemistry
, vol.37
, pp. 17882-17889
-
-
Naiki, H.1
Hasegawa, K.2
Yamaguchi, I.3
Nakamura, H.4
Gejyo, F.5
Nakakuki, K.6
-
32
-
-
0013325776
-
-
note
-
We use the term conformational state within its thermodynamic and statistical thermodynamic sense to indicate all conformations of a protein and its environment (i.e., solvent and additional solutes) within a given ensemble, or rational subdivision of an ensemble, consistent with a set of macroscopic observables specific to that state.
-
-
-
-
33
-
-
0030628825
-
-
Onuchic, J. N.; Luthey-Schulten, Z.; Wolynes, P. G. Annu. Rev. Phys. Chem. 1997, 48, 545-600.
-
(1997)
Annu. Rev. Phys. Chem.
, vol.48
, pp. 545-600
-
-
Onuchic, J.N.1
Luthey-Schulten, Z.2
Wolynes, P.G.3
-
34
-
-
36448999595
-
-
Abkevich, V. I.; Gutin, A. M.; Shakhnovich, E. I. J. Chem. Phys. 1994, 101, 6052-6062.
-
(1994)
J. Chem. Phys.
, vol.101
, pp. 6052-6062
-
-
Abkevich, V.I.1
Gutin, A.M.2
Shakhnovich, E.I.3
-
35
-
-
0037150072
-
-
Krishnan, S.; Chi, E. Y.; Webb, J. N.; Chang, B. S.; Shan, D.; Goldenberg, M.; Manning, M. C.; Randolph, T. W.; Carpenter, J. F. Biochemistry, 2002, 41, 6422.
-
(2002)
Biochemistry
, vol.41
, pp. 6422
-
-
Krishnan, S.1
Chi, E.Y.2
Webb, J.N.3
Chang, B.S.4
Shan, D.5
Goldenberg, M.6
Manning, M.C.7
Randolph, T.W.8
Carpenter, J.F.9
-
36
-
-
0035865589
-
-
Lindner, R. A.; Treweek, T. M.; Carver, J. A. Biochem. J. 2001, 354, 79-87.
-
(2001)
Biochem. J.
, vol.354
, pp. 79-87
-
-
Lindner, R.A.1
Treweek, T.M.2
Carver, J.A.3
-
38
-
-
0035957228
-
-
Khurana, R.; Gillespie, J. R.; Talapatra, A.; Minert, L. J.; Jonescu-Zanetti, C.; Millett, I.; Fink, A. L. Biochemistry 2001, 40, 3525-3535.
-
(2001)
Biochemistry
, vol.40
, pp. 3525-3535
-
-
Khurana, R.1
Gillespie, J.R.2
Talapatra, A.3
Minert, L.J.4
Jonescu-Zanetti, C.5
Millett, I.6
Fink, A.L.7
-
39
-
-
0013373092
-
-
note
-
38,40,41
-
-
-
-
40
-
-
0008863560
-
-
Anfinsen, C. B., anson, M. L., Bailey, K., Edsall, J. T., Eds.; Academic Press: New York
-
Kauzmann, W. In Advances in Protein Chemistry; Anfinsen, C. B., Anson, M. L., Bailey, K., Edsall, J. T., Eds.; Academic Press: New York, 1959; Vol. 14, pp 1-63.
-
(1959)
Advances in Protein Chemistry
, vol.14
, pp. 1-63
-
-
Kauzmann, W.1
-
43
-
-
0013419250
-
-
note
-
For the purposes of the extended Lumry-Eyring model employed here as well for extrapolating shelf-life predictions, it is not necessary to know detailed identity (e.g., in terms of structural details) of the aggregation-prone state(s). The major requirement is that it(they) remain the predominant aggregation-prone state(s) over the range of the variable being extrapolated.
-
-
-
-
48
-
-
0000352830
-
-
La Rosa, C.; Milardi, D.; Grasso, D.; Guzzi, R.; Sportelli, L. J. Phys. Chem. 1995, 99, 14864-14870.
-
(1995)
J. Phys. Chem.
, vol.99
, pp. 14864-14870
-
-
La Rosa, C.1
Milardi, D.2
Grasso, D.3
Guzzi, R.4
Sportelli, L.5
-
49
-
-
0013425606
-
-
Kasraian, K.; Kuzniar, A.; Earley, D.; Kamicker, B.; Wilson, G.; Manion, T.; Hong, J.; Reiber, C.; Canning, P. Pharm. Dev. Technol. 2001, 6, 439-445.
-
(2001)
Pharm. Dev. Technol.
, vol.6
, pp. 439-445
-
-
Kasraian, K.1
Kuzniar, A.2
Earley, D.3
Kamicker, B.4
Wilson, G.5
Manion, T.6
Hong, J.7
Reiber, C.8
Canning, P.9
-
50
-
-
0035912726
-
-
Webb, J.N.; Webb, S. D.; Cleland, J. L.; Carpenter, J. F.; Randolph, T. W. Proc. Natl. Acad. Sci U.S.A. 2001, 98, 7259.
-
(2001)
Proc. Natl. Acad. Sci U.S.A.
, vol.98
, pp. 7259
-
-
Webb, J.N.1
Webb, S.D.2
Cleland, J.L.3
Carpenter, J.F.4
Randolph, T.W.5
-
52
-
-
0013326631
-
-
note
-
0).
-
-
-
-
53
-
-
0000594410
-
-
Fields, G. B.; Alonso, D. O. V.; Stigter, D.; Dill, K. A. J. Phys. Chem. 1992, 96, 3974.
-
(1992)
J. Phys. Chem.
, vol.96
, pp. 3974
-
-
Fields, G.B.1
Alonso, D.O.V.2
Stigter, D.3
Dill, K.A.4
-
54
-
-
0036239473
-
-
Bartkowski, R. E.; Kitchel, R.; Peckham, N. R.; Margulis, J. J. Protein Chem. 2002, 21, 137.
-
(2002)
J. Protein Chem.
, vol.21
, pp. 137
-
-
Bartkowski, R.E.1
Kitchel, R.2
Peckham, N.R.3
Margulis, J.4
-
56
-
-
0002343673
-
-
Creighton, T. E., Ed.; Oxford University Press: Oxford, U.K.
-
Pace, C. N.; Shirley, B. A.; Thomson, J. A. In Protein Structure; Creighton, T. E., Ed.; Oxford University Press: Oxford, U.K., 1990; p. 311.
-
(1990)
Protein Structure
, pp. 311
-
-
Pace, C.N.1
Shirley, B.A.2
Thomson, J.A.3
-
58
-
-
0001857002
-
-
Ducruix, A., Giege, R., Eds.; Oxford University Press: New York
-
Mikol, V.; Giege, R. In Crystallization of Nucleic Acids and Proteins; Ducruix, A., Giege, R., Eds.; Oxford University Press: New York, 1992; pp 219-240.
-
(1992)
Crystallization of Nucleic Acids and Proteins
, pp. 219-240
-
-
Mikol, V.1
Giege, R.2
-
59
-
-
0013375241
-
-
note
-
3 days.
-
-
-
-
60
-
-
0032084472
-
-
Teplow, D. B. Amyloid 1998, 5, 121-142.
-
(1998)
Amyloid
, vol.5
, pp. 121-142
-
-
Teplow, D.B.1
-
64
-
-
0003224438
-
Arrhenius consequences of IL-1R(II) aggregation in the vicinity of the Tm
-
IBC USA, Miami, FL
-
Remmele, R. A. Arrhenius Consequences of IL-1R(II) Aggregation in the Vicinity of the Tm. Formulation Strategies for Biopharmaceuticals, IBC USA, Miami, FL, 2002.
-
(2002)
Formulation Strategies for Biopharmaceuticals
-
-
Remmele, R.A.1
-
66
-
-
0028981210
-
-
Oliveberg, M.; Tan, Y.-J.; Fersht, A. R. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 8926-8929.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 8926-8929
-
-
Oliveberg, M.1
Tan, Y.-J.2
Fersht, A.R.3
-
67
-
-
0025818591
-
-
Yoshioka, S.; Izutsu, K.; Aso, Y.; Takeda, Y. Pharm. Res. 1991, 8, 480-484.
-
(1991)
Pharm. Res.
, vol.8
, pp. 480-484
-
-
Yoshioka, S.1
Izutsu, K.2
Aso, Y.3
Takeda, Y.4
-
68
-
-
0037108179
-
-
Goers, J.; Permyakov, S. E.; Permyakov, E. A.; Uversky, V. N.; Fink, A. L. Biochemistry 2002, 41, 12546-12551.
-
(2002)
Biochemistry
, vol.41
, pp. 12546-12551
-
-
Goers, J.1
Permyakov, S.E.2
Permyakov, E.A.3
Uversky, V.N.4
Fink, A.L.5
|