Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport

EMBO Journal

Volumn 22, Issue 22, 2003, Pages 6004-6015

  Hoogenraad, Casper C ^a   Wulf, Phebe ^a   Schiefermeier, Natalia ^b   Stepanova, Tatiana ^a   Galjart, Niels ^a   Small, J Victor ^b   Grosveld, Frank ^a   De Zeeuw, Chris I ^a   Akhmanova, Anna ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

Cytoplasmic dynein; Dynactin; Kinesin; Mitochondria; Peroxisomes

Indexed keywords

BICAUDAL D PROTEIN; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ORGANELLE; CHIMERA; MICROTUBULE; MITOCHONDRION; MOLECULAR MECHANICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN TRANSPORT;

DROSOPHILA PROTEINS; DYNEIN ATPASE; GENES, REPORTER; HUMANS; LIPOPROTEINS; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULE-ORGANIZING CENTER; MICROTUBULES; MITOCHONDRIA; PEROXISOMES; RECOMBINANT FUSION PROTEINS;

MAMMALIA;

EID: 0344011612     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg592     Document Type: Article

References (41)

1. Allan, V. (2000) Dynactin. Curr. Biol., 10, R432.
2. Baens, M. and Marynen, P. (1997) A human homologue (BICD1) of the Drosophila bicaudal-D gene. Genomics, 45, 601-606.
3. Bear, J.E., Loureiro, J.J., Libova, I., Fassler, R., Wehland, J. and Gertler, F.B. (2000) Negative regulation of fibroblast motility by Ena/VASP proteins. Cell, 101, 717-728.
4. Bubeck, P., Pistor, S., Wehland, J. and Jockusch, B.M. (1997) Ligand recruitment by vinculin domains in transfected cells. J. Cell Sci., 110, 1361-1371.
5. Bullock, S.L. and Ish-Horowicz, D. (2001) Conserved signals and machinery for RNA transport in Drosophila oogenesis and embryogenesis. Nature, 414, 611-616.
6. Burkhardt, J.K., Echeverri, C.J., Nilsson, T. and Vallee, R.B. (1997) Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J. Cell Biol., 139, 469-484.
7. De Vos, K., Goossens, V., Boone, E., Vercammen, D., Vancompernolle, K., Vandenabeele, P., Haegeman, G., Fiers, W. and Grooten, J. (1998) The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region. J. Biol. Chem., 273, 9673-9680.
8. De Vos, K., Severin, F., Van Herreweghe, F., Vancompernolle, K., Goossens, V., Hyman, A. and Grooten, J. (2000) Tumor necrosis factor induces hyperphosphorylation of kinesin light chain and inhibits kinesin-mediated transport of mitochondria. J. Cell Biol., 149, 1207-1214.
9. Deacon, S.W., Serpinskaya, A.S., Vaughan, P.S., Lopez Fanarraga, M., Vemos, I., Vaughan, K.T. and Gelfand, V.I. (2003) Dynactin is required for bidirectional organelle transport. J. Cell Biol., 160, 297-301.
10. Echeverri, C.J., Paschal, B.M., Vaughan, K.T. and Vallee, R.B. (1996) Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis. J. Cell Biol., 132, 617-633.
11. Goldstein, L.S. and Yang, Z. (2000) Microtubule-based transport systems in neurons: the roles of kinesins and dyneins. Annu. Rev. Neurosci., 23, 39-71.
12. Gross, S.P. (2003) Dynactin: coordinating motors with opposite inclinations. Curr. Biol., 13, R320-R322.
13. Helfand, B.T., Mikami, A., Vallee, R.B. and Goldman, R.D. (2002) A requirement for cytoplasmic dynein and dynactin in intermediate filament network assembly and organization. J. Cell Biol., 157, 795-806.
14. Hirokawa, N., Noda, Y. and Okada, Y. (1998) Kinesin and dynein superfamily proteins in organelle transport and cell division. Curr. Opin. Cell Biol., 10, 60-73.
15. Hoogenraad, C.C., Akhmanova, A., Grosveld, F., De Zeeuw, C.I. and Galjart, N. (2000) Functional analysis of CLIP-115 and its binding to microtubules. J. Cell Sci., 113, 2285-2297.
16. Hoogenraad, C.C., Akhmanova, A., Howell, S.A., Dortland, B.R., De Zeeuw, C.I., Willemsen, R., Visser, P., Grosveld, F. and Galjart, N. (2001) Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes. EMBO J., 20, 4041-4054.
17. Karki, S. and Holzbaur, E.L. (1999) Cytoplasmic dynein and dynactin in cell division and intracellular transport. Curr. Opin. Cell Biol., 11, 45-53.
18. King, S.J. and Schroer, T.A. (2000) Dynactin increases the processivity of the cytoplasmic dynein motor. Nat. Cell Biol., 2, 20-24.
19. Krylyshkina, O., Kaverina, I., Kranewitter, W., Steffen, W., Alonso, M.C., Cross, R.A. and Small, J.V. (2002) Modulation of substrate adhesion dynamics via microtubule targeting requires kinesin-1. J. Cell Biol., 156, 349-359.
20. Ligon, L.A., Karki, S., Tokito, M. and Holzbaur, E.L. (2001) Dynein binds to beta-catenin and may tether microtubules at adherens junctions. Nat. Cell Biol., 3, 913-917.
21. Matanis, T. et al. (2002) Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex. Nat. Cell Biol., 4, 986-992.
22. Muresan, V., Stankewich, M.C., Steffen, W., Morrow, J.S., Holzbaur, E.L. and Schnapp, B.J. (2001) Dynactin-dependent, dynein-driven vesicle transport in the absence of membrane proteins: a role for spectrin and acidic phospholipids. Mol. Cell, 7, 173-183.
23. Pistor, S., Chakraborty, T., Niebuhr, K., Domann, E. and Wehland, J. (1994) The ActA protein of Listeria monocytogenes acts as a nucleator inducing reorganization of the actin cytoskeleton. EMBO J., 13, 758-763.
24. Pollock, R., Issner, R., Zoller, K., Natesan, S., Rivera, V.M. and Clackson, T. (2000) Delivery of a stringent dimerizer-regulated gene expression system in a single retroviral vector. Proc. Natl Acad. Sci. USA, 97, 13221-13226.
25. Purohit, A., Tynan, S.H., Vallee, R. and Doxsey, S.J. (1999) Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization. J. Cell Biol., 147, 481-492.
26. Quintyne, N.J., Gill, S.R., Eckley, D.M., Crego, C.L., Compton, D.A. and Schroer, T.A. (1999) Dynactin is required for microtubule anchoring at centrosomes. J. Cell Biol., 147, 321-334.
27. Rivera, V.M. et al. (1996) A humanized system for pharmacologic control of gene expression. Nat. Med., 2, 1028-1032.
28. Schnorrer, F., Bohmann, K. and Nusslein-Volhard, C. (2000) The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes. Nat. Cell Biol., 2, 185-190.
29. Schrader, M., King, S.J., Stroh, T.A. and Schroer, T.A. (2000) Real time imaging reveals a peroxisomal reticulum in living cells. J. Cell Sci., 113, 3663-3671.
30. Schroer, T. (1996) Structure and function of dynactin. Semin. Cell Dev. Biol., 7, 321-328.
31. Short, B., Preisinger, C., Schaletzky, J., Kopajtich, R. and Barr, F.A. (2002) The Rab6 GTPase regulates recruitment of the dynactin complex to Golgi membranes. Curr. Biol., 12, 1792-1795.
32. Soukupova, M., Sprenger, C., Gorgas, K., Kunau, W.H. and Dodt, G. (1999) Identification and characterization of the human peroxin PEX3. Eur. J. Cell Biol., 78, 357-374.
33. Stamer, K., Vogel, R., Thies, E., Mandelkow, E. and Mandelkow, E.M. (2002) Tau blocks traffic of organelles, neurofilaments and APP vesicles in neurons and enhances oxidative stress. J. Cell Biol., 156, 1051-1063.
34. Steffen, W., Karki, S., Vaughan, K.T., Vallee, R.B., Holzbaur, E.L., Weiss, D.G. and Kuznetsov, S.A. (1997) The involvement of the intermediate chain of cytoplasmic dynein in binding the motor complex to membranous organelles of Xenopus oocytes. Mol. Biol. Cell, 8, 2077-2088.
35. Stowers, R.S., Megeath, L.J., Gorska-Andrzejak, J., Meinertzhagen, I.A. and Schwarz, T.L. (2002) Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein. Neuron, 36, 1063-1077.
36. Suter, B., Romberg, L.M. and Steward, R. (1989) Bicaudal-D, a Drosophila gene involved in developmental asymmetry: localized transcript accumulation in ovaries and sequence similarity to myosin heavy chain tail domains. Genes Dev., 3, 1957-1968.
37. Swan, A., Nguyen, T. and Suter, B. (1999) Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning. Nat. Cell Biol., 1, 444-449.
38. Tai, A.W., Chuang, J.Z., Bode, C., Wolfrum, U. and Sung, C.H. (1999) Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1. Cell, 97, 877-887.
39. Tanaka, Y., Kanai, Y., Okada, Y., Nonaka, S., Takeda, S., Harada, A. and Hirokawa, N. (1998) Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria. Cell, 93, 1147-1158.
40. Voorn-Brouwer, T., Kragt, A., Tabak, H.F. and Distel, B. (2001) Peroxisomal membrane proteins are properly targeted to peroxisomes in the absence of COPI- and COPII-mediated vesicular transport. J. Cell Sci., 114, 2199-2204.
41. Wharton, R.P. and Struhl, G. (1989) Structure of the Drosophila Bicauda1D protein and its role in localizing the the posterior determinant nanos. Cell, 59, 881-892.