Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina

Cell

Volumn 108, Issue 1, 2002, Pages 83-96

  Beaudouin, Joël ^a   Gerlich, Daniel ^b   Daigle, Nathalie ^a   Eils, Roland ^b   Ellenberg, Jan ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LAMIN B;

ANIMAL CELL; ARTICLE; BASEMENT MEMBRANE; CELL DISRUPTION; CELL LINE; CELL NUCLEUS MEMBRANE; CENTROSOME; CHROMOSOME CONDENSATION; CONTROLLED STUDY; DEPOLYMERIZATION; MICROTUBULE; MITOSIS; NONHUMAN; PRIORITY JOURNAL; RAT; TENSION;

ANIMALIA;

EID: 0037059611     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)00627-4     Document Type: Article

References (54)

1. Formation of spindle fibers, kinetochore orientation, and behavior of the nuclear envelope during mitosis in endosperm
2. An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells
3. Domain-specific disassembly and reassembly of nuclear membranes during mitosis
4. Dynein and dynactin are localized to astral microtubules and at cortical sites in mitotic epithelial cells
5. The lamin B receptor of the inner nuclear membrane undergoes mitosis-specific phosphorylation and is a substrate for p34cdc2-type protein kinase
6. Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells
7. Temporal differences in the appearance of NEP-B78 and an LBR-like protein during Xenopus nuclear envelope reassembly reflect the ordered recruitment of functionally discrete vesicle types
8. Fluorescence photobleaching techniques
9. Dynamics and mobility of nuclear envelope proteins in interphase and mitotic cells revealed by green fluorescent protein chimeras
10. Nuclear membrane dynamics and reassembly in living cells: Targeting of an inner nuclear membrane protein in interphase and mitosis
11. Cell cycle-dependent phosphorylation of nucleoporins and nuclear pore membrane protein Gp210
12. Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: Three-dimensional organization and protein composition
13. Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes, and binding is modulated by mitotic phosphorylation
14. Cloning of a cDNA for lamina-associated polypeptide 2 (LAP2) and identification of regions that specify targeting to the nuclear envelope
15. Nuclear envelope breakdown in mammalian cells involves stepwise lamina disassembly and microtubule-drive deformation of the nuclear membrane
16. The nuclear envelope lamina is reversibly depolymerized during mitosis
17. Functional organization of the nuclear envelope
18. 4-D imaging and quantitative reconstruction to analyze complex spatiotemporal processes in live cells
19. Structural and functional organization of the nuclear envelope
20. Cytoplasmic dynein is required for distinct aspects of MTOC positioning, including centrosome separation, in the one cell stage Caenorhabditis elegans embryo
21. Review: Nuclear lamins - Structural proteins with fundamental functions
22. Projections of the nuclear envelope into the nucleus prior to its breakdown
23. Mutations of phosphorylation sites in lamin A that prevent nuclear lamina disassembly in mitosis
24. Steps of nuclear pore complex disassembly and reassembly during mitosis in early Drosophila embryos
25. C. elegans nuclear envelope proteins emerin, MAN1, lamin, and nucleoporins reveal unique timing of nuclear envelope breakdown during mitosis
26. An ultrastructural analysis of mitosis and cytokinesis in the zygote of the sea urchin, Arbacia punctulata
27. Dynein intermediate chain mediated dynein-dynactin interaction is required for interphase microtubule organization and centrosome replication and separation in Dictyostelium
28. Differential mitotic phosphorylation of proteins of the nuclear pore complex
29. Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure
30. Nuclear envelope assembly after mitosis
31. Disassembly of the nucleus in mitotic extracts: Membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes
32. Fine structural studies of early mitotic stages in untreated and nocodazole-treated HeLa cells
33. In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase
34. Disassembly of in vitro formed lamin head-to-tail polymers by CDC2 kinase
35. Assembly/disassembly of the nuclear envelope membrane: Cell cycle-dependent binding of nuclear membrane vesicles to chromatin in vitro
36. Cytoplasmic dynein and actin-related protein Arp1 are required for normal nuclear distribution in filamentous fungi
37. ER-to-Golgi transport visualized in living cells
38. Mechanisms of nuclear positioning
39. The ultrastructure of a mammalian cell during the mitotic cell cycle
40. Cytoplasmic dynein is required for the nuclear attachment and migration of centrosomes during mitosis in Drosophila
41. A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein
42. Cytoplasmic dynein as a facilitator of nuclear envelope breakdown
43. In vitro nuclear assembly with affinity-purified nuclear envelope precursor vesicle fractions, PV1 and PV2
44. The fates of chicken nuclear lamin proteins during mitosis: Evidence for a reversible redistribution of lamin B2 between inner nuclear membrane and elements of the endoplasmic reticulum
45. Dynamics of the endoplasmic reticulum and golgi apparatus during early sea urchin development
46. A new model for nuclear envelope breakdown
47. Identification of cell cycle-regulated phosphorylation sites on nuclear lamin C
48. The nuclear envelope, muscular dystrophy and gene expression
49. A cytoplasmic dynein heavy chain is required for oscillatory nuclear movement of meiotic prophase and efficient meiotic recombination in fission yeast
50. Integral membrane proteins of the nuclear envelope are dispersed throughout the endoplasmic reticulum during mitosis
51. Primary structure analysis and lamin B and DNA binding of human LBR, an integral protein of the nuclear envelope inner membrane
52. Golgi membranes are absorbed into and reemerge from the ER during mitosis
53. Some structural aspects of the fate of the nuclear envelope during mitosis