A requirement for cytoplasmic dynein and dynactin in intermediate filament network assembly and organization

Journal of Cell Biology

Volumn 157, Issue 5, 2002, Pages 795-806

  Helfand, Brian T ^a   Mikami, Atsushi ^b   Vallee, Richard B ^b   Goldman, Robert D ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Cytoskeleton; Dynactin; Dynein; Intermediate filaments; Vimentin

Indexed keywords

ACTIN; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; PROTEIN SUBUNIT; VIMENTIN;

ANIMAL CELL; ARTICLE; CELL SURFACE; CONTROLLED STUDY; CYTOSKELETON; IMMUNOFLUORESCENCE; INTERMEDIATE FILAMENT; MICROTUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN TRANSPORT;

ANIMALS; CELLS, CULTURED; CRICETINAE; DYNEIN ATPASE; GENE EXPRESSION; INTERMEDIATE FILAMENTS; KIDNEY; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; REPLICA TECHNIQUES; TRANSFECTION; VIMENTIN;

ANIMALIA; CRICETINAE;

EID: 0037182581     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200202027     Document Type: Article

References (57)

1. Kinesin associated with vimentin intermediate filaments contains a specific light chain
2. Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution
3. New horizons in cytoskeletal dynamics: Transport of intermediate filaments along microtubule tracks
4. The neurotoxins 2,5-hexanedione and acrylamide promote aggregation of intermediate filaments in cultured fibroblasts
5. Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis
6. Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product
7. A novel interaction of the Golgi complex with the vimentin intermediate filament cytoskeleton
8. Interaction of the p62 subunit of dynactin with Arp1 and the cortical actin cytoskeleton
9. The role of three cytoplasmic fibers in BHK-21 cell motility. I. Microtubules and the effects of colchicine
10. Coalignment of vimentin intermediate filaments with microtubules depends on kinesin
11. Aggresomes resemble sites specialized for virus assembly
12. Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles
13. Beta III spectrin binds to the Arp1 subunit of dynactin
14. Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation
15. Neurofilaments in health and disease
16. Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex
17. Dynactin increases the processivity of the cytoplasmic dynein motor
18. Detyrosination of tubulin regulates the interaction of intermediate filaments with microtubules in vivo via a kinesin-dependent mechanism
19. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
20. Modulation of vimentin containing intermediate filament distribution and phosphorylation in living fibroblasts by the cAMP-dependent protein kinase
21. Kinesin is a candidate for cross-bridging microtubules and intermediate filaments. Selective binding of kinesin to detyrosinated tubulin and vimentin
22. Cloning and expression of a human kinesin heavy chain gene: Interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells
23. KIFC3, a microtubule minus end-directed motor for the apical transport of annexin XIIIb-associated Triton-insoluble membranes
24. Direct demonstration of the presence of two immunologically distinct intermediate-sized filament systems in the same cell by double label immunofluorescence microscopy. Vimentin and cytokeratin fibers in cultured epithelial cells
25. Giant axonal neuropathy: An inborn error of organization of intermediate filaments
26. Rapid movements of vimentin on microtubule tracks: Kinesin-dependent assembly of intermediate filament networks
27. Fast transport of neurofilament protein along microtubules in squid axoplasm
28. ER-to-Golgi transport visualized in living cells
29. Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization
30. Dynactin is required for microtubule anchoring at centrosomes
31. Associations of elements of the Golgi apparatus with microtubules
32. Dynamic association of cytoplasmic dynein heavy chain la with the Golgi apparatus and intermediate compartment
33. Neurofilaments are transported rapidly but intermittently in axons: Implications for slow axonal transport
34. Bidirectional translocation of neurofilaments along microtubules mediated in part by dynein/dynactin
35. Cytoplasmic dynein is required for poleward chromosome movement during mitosis in Drosophila embryos
36. Isolation and preliminary, characterization of 10-nm filaments from baby hamster kidney (BHK-21) cells
37. ZW10 helps recruit dynactin and dynein to the kinetochore
38. Alterations in neural intermediate filament organization: Functional implications and the induction of pathological changes related to motor neuron disease
39. Microtubule-dependent plus- and minus end-directed motilities are competing processes for nuclear targeting of adenovirus
40. Improved procedures for electron microscopic visualization of the cytoskeleton of cultured cells
41. Rhodopsin's catboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1
42. Role of ]dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function
43. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
44. Distinct but overlapping sites within the cytoplasmic dynein heavy chain for dimerization and for intermediate chain and light intermediate chain binding
45. Light intermediate chain 1 defines a functional subfraction of cytoplasmic dynein which binds to pericentrin
46. Targeting of motor proteins
47. Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p 150Glued
48. Nonsarcomeric mode of myosin II organization in the fibroblast lamellum
49. A novel tau transcript in cultured human neuroblastoma cells expressing nuclear tau
50. Rapid movement of axonal neurofilaments interrupted by prolonged pauses
51. Morphological study of the mammalian stress response: Characterization of changes in cytoplasmic organelles, cytoskeleton, and nucleoli, and appearance of intranuclear actin filaments in rat fibroblasts after heat-shock treatment
52. Kinesin-mediated transport of neurofilament protein oligomers in growing axons
53. A 300,000-molwt intermediate filament-associated protein in baby hamster kidney (BHK-21) cells
54. Association of Trk neurotrophin receptors with components of the cytoplasmic dynein motor
55. The motility and assembly of keratin tonofibrils in living epithelial cells
56. Motile properties of vimentin intermediate filament networks in living cells
57. Cytoplasmic dynein-mediated assembly of pericentrin and gamma tubulin onto centrosomes