Characterization of the rat and mouse homologues of the BRCA2 breast cancer susceptibility gene

Cancer Research

Volumn 57, Issue 15, 1997, Pages 3121-3125

  McAllister, Kimbcrly A ^a   Haugen Strano, Astrid ^a   Hagevik, Sarah ^a   Brownlee, Heather A ^a   Keith Collins, N ^a   Andrew Futreal, P ^b   Michelle Bennett, L ^a   Wiseman, Roger W ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR PROTEIN; TUMOR SUPPRESSOR PROTEIN BRCA 2; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER SUSCEPTIBILITY; GENE MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SEQUENCE HOMOLOGY; TUMOR SUPPRESSOR GENE;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; BRCA2 PROTEIN; CONSENSUS SEQUENCE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; POLYMORPHISM, GENETIC; RATS; SEQUENCE ALIGNMENT; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS;

EID: 0030854835     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Stratton, M. R. Recent advances in understanding of genetic susceptibility to breast cancer. Hum. Mol. Genet., 5: 1515-1519, 1996.
2. Wooster, R., Neuhausen, S. L., Mangion, J., Quirk, J., Ford, D., CoIIins, N., Nguyen, K., Seal, S., Tran, T., Averill, D., Fields, P., Marshall, G., Narod, S., Lenoir, G., Lynch, H., Feuntcun, J., Devilee, P., Cornelisses, C. J., Menko, F. H., Daly, P. A., Ormiston, W., McManus, R., Pye, R., Lewis, C. M., Cannon-Albright, L. A., Peto, J., Ponder, B. A. J., Skolnick, M. H., Easton, D. F., Goldgar, D. E., and Stratton, M. R. Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13. Science (Washington DC), 265: 2088-2090, 1994.
3. Wooster, R., Bignell, G., Lancaster, J. M., Swift, S., Seal, S., Mangion, J., Collins, N., Gregory, S., Gumbs, C., Micklem, G., Barfoot, R., Hmoudi, R., Patel, S., Rice, C., Biggs, P., Hashim, Y., Smith, A., Conner, R, Arason, A., Gudmundsson, J., Ficenec, D., Kelsell, D., Ford, D., Tonin, P., Bishop, D. T., Spurr, N. K., Ponder, B. A. J., Eeles, R., Peto, J., Devilee, P., Cornelisse, D., Lynch, H., Narod, S., Lcnoir, G., Egilsson, V., Barkadolir, R. B., Easton, D. F., Bentley, D. R., Futreal, P. A., Ashworth, A., and Stralton, M. R. Identification of the breast cancer susceptibility gene BRCA2. Nature (Lond.), 378: 789-792, 1995.
4. Tavtigian, S. V., Simard, J., Rommens, J., Couch, F., Shattuck-Eidens, D., Neuhausen, S., Merajver, S., Thorlacius, S., Offit, K., Stoppa-Lyonnet, D., Belanger, C, Bell, R., Berry, S., Bogden, R., Chen, Q., Davis, T., Dumont, M., Frye, C., Hattier, T., Jammulapati, S., Janecki, T., Jiang, P., Kehrer, R., Leblanc, J-F., Mitchell, J. T., McArthur-Monison, J., Nguyen, K., Peng, Y., Samson, C., Schroeder, M., Snyder, S. C, Steele, L., Stringfellow, M., Stroup, C., Swedlund, B., Swenson, J., Teng, D., Tranchant, M., Weaver-Feldhaus, J., Wong, A. K. C., Shizuya, H., Eyfijord, J. E., Cannon-Albright, L., Labrie, F., Skolnick, M. H., Weber, B., Kamb, A., and Goldgar, D. E. The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds. Nat. Genet., 12: 333-337, 1996.
5. Miki, Y., Swenson, J., Shattuck-Eidens, D., Futreal, P. A., Harshman, K., Tavtigian, S., Liu, Q., Cochran, C., Bennett, L. M., Ding, W., Bell, R., Rosenthal, J., Hussey, C., Tran, T., McClure, M., Frye, C., Hattier, T., Phelps, R., Haugen-Strano, A., Katcher, H., Yakumo, K., Gholami, Z., Shaffer, D., Stone, S., Bayer, S., Wray, C., Borgden, R., Dayananth, P., Ward, J., Tonin, P., Narod, S., Bristow, P., Norris, F., Helvering, L.. Morrison, P., Roseteck, P., Lai, M., Barrett, J. C., Lewis, C., Neuhausen, S., Cannon-Albright, L., Goldgar, D., Wiseman, R. W., Kamb, A., and Skolnick, M. H. A strong candidate for the 17q-linked breast and ovarian cancer susceptibility gene BRCA1. Science (Washington DC), 266: 66-71, 1994.
6. Jensen, R. A., Thompson, M. E., Jetton, T. L., Szabo, C., van der Meer, R., King, M-C, and Holt, J. T. BRCA1 is secreted and exhibits properties of a granin. Nat. Genet., 12: 303-308, 1996.
7. Bork, P., Blomberg, N., and Nigles, M. Internal repeats in the BRCA2 protein sequence. Nat. Genet., 13: 22-23, 1996.
8. Bignell, G., Micklem, G., Stratum, M. R., Ashworth, A., and Wooster, R. The BRC repeats are conserved in mammalian BRCA2 proteins. Hum. Mol. Gen., 6: 53-58,1997.
9. Bennett, L. M., Haugen-Strano, A., Cochran, C., Fiedorek, F. T., and Wiseman, R. W. Isolation of the mouse homologue of BRCAI and genetic mapping to mouse chromosome 11. Genomics, 29: 576-581, 1995.
10. Nakai, K., and Kanehisa, M. A knowledge base for predicting protein localization sites in eukaryotic cells. Genomics, 14: 897-911, 1992.
11. Makalowski, W., Zhang, J., and Boguski, M. S. Comparative analysis of 1196 orthologous mouse and human full-length mRNA and protein sequences. Genome Res., 6: 846-857, 1996.
12. Bennett, L. M., Brownlee, H., Hagevik, S., Haugen-Strano, A., and Wiseman, R. W. Evolutionarily conserved domains of the rat BRCA1 protein. Proc. Am. Assoe. Cancer Res., 37: 3518, 1996.
13. Szabo, C., Wagner, L. A., Francisco, L. V., Roach, J. C., Argonza, R., King, M-C., and Ostrander, E. A. Human, canine, and murine BRCA1 genes: sequence comparison among species. Hum. Mol. Genet., 5: 1289-1298, 1996.
14. McAllister, K. A., Ramachandran, S., Haugen-Strano, A., Fiedorek, F. T., Jr., and Wiseman, R. W. Genetic mapping of the Brca2 breast cancer susceptibility gene on mouse Chromosome 5. Mamm. Genome, 8: 540-541, 1997.
15. Vaughn, J. P., Cirisano, F. D., Huper, G., Berchuck, A., Futreal, P. A., Marks, J. R., and Iglehart, J. D. Cell cycle control of BRCA2. Cancer Res., 56: 4590-4594, 1996.
16. Rajan, J. V., Wang, M., Marquis, S. T., and Chodosh, L. A. Brca2 is coordinately regulated with Brcal during proliferation and differentiation in mammary epithelial cells. Proc. Natl. Acad. Sei. USA. 93: 13078-13083, 1996.
17. Mazoyer, S., Dunning, A:M., Serova, O., Dearden, J., Puget, N., Healey, C. S., Gayther, S. A., Mangion, J., Stratton, M. R., Lynch, H. T., Goldgar, D. E., Ponder, B. A. J. and Lenoir, G. M. A. Polymorphic stop codon in BRCA2. Nat. Genet., 14: 253-254, 1996.
18. Chapman, M. S., and Verma, I. M. Transcriptional activation of BRCAI. Nature (Lond.), 382: 266-268, 1996.
19. Boulikas, T. Putative nuclear localization signals (NLS) in protein transcription factors. J. Cell. Biochem., 55: 32-58, 1994.
20. Scully, R., Chen, J., Plug, A., Xiao, Y., Weaver, D., Feunteun, J., Ashley, T., and Livingston, D. M. Association of BRCAI with Rad51 in mitotic and meiotic cells. Cell, 88: 265-275, 1997.
21. Friend, S., Borrensen, A-L., Brody, L., Casey, G., Devilee, P., Gayther, S., Goldgar, D., Weber, B. L., and Wiseman, R. W. Breast cancer information on the web. Nat. Genet., 11: 238-239, 1995.
22. Couch, F. J., Farid, L. M., DeShano, M. L., Tavtigian, S. V., Calzone, K., Campcau, L., Peng, Y., Bogden, B., Chen, Q., Neuhausen, S., Shattuck-Eidens, D., Godwin, A. K., Daly, M., Radford, D. M., Sedlacek, S., Rommens, J., Simard, J., Garber, J., Merajver, S., and Weber, B. L. BRCA2 germline mutations in male breast cancer cases and breast cancer families. Nat. Genet., 13: 123-125, 1996.
23. Teng, D. H. F., Bogden, R., Mitchell, J., Baumgard, M., Bell, R., Berry, S., Davis, T., Ha, P. C, Kehrer, R., Jammulapati, S., Chen, Q., Offit, K., Skolnick, M. H., Tavtigian, S. V., Jhanwar, S., Swedlund, B., Wong, A. K. C., and Kamb, A. Low incidence of BRCA2 mutations in breast carcinoma and other cancers. Nat. Genet., 13: 241-244, 1996.
24. Miki, Y., Katagiri, T., Kasumi, F., Yoshimoto, T., and Nakamura, Y. Mutation analysis in the BRCA2 gene in primary breast cancers. Nat. Genet., 13: 245-247, 1996.
25. Takahashi, H., Chiu, H-C, Bandera, C. A., Bahbakht, K., Liu, P. C., Couch. F. J., Weber, B. L., LiVolsi, V. A., Furusato, M., Rebane, B. A., Cardonick, A., Benjamin, I., Morgan, M. A., King, S. A., Mikuta, J. J., Rubin, S. C, and Boyd, J. Mutations of the BRCA2 gene in ovarian carcinomas. Cancer Res., 56: 2738-2741, 1996.
26. Lancaster, J. M., Wooster, R., Mangion, J., Phelan, C. M., Cochran, C., Gumbs, C., Seal, S., Barfoot, R., Collins, N., Bignell, G., Patel, S., Hamoudi, R., Larsson, C., Wiseman, R. W., Berchuck, A., Iglehan, J. D., Marks, J. R., Ashworth, A., Stratton, M. R., and Futreal, P. A. BRCA2 mutations in primary breast and ovarian cancers. Nat. Genet., 13: 238-240, 1996.