-
1
-
-
0034831067
-
Nonalcoholic steatohepatitis
-
Reid A. Nonalcoholic steatohepatitis. Gastroenterology. 121:2001;710-723
-
(2001)
Gastroenterology
, vol.121
, pp. 710-723
-
-
Reid, A.1
-
2
-
-
0037129380
-
Nonalcoholic fatty liver disease
-
Angulo P. Nonalcoholic fatty liver disease. N Engl J Med. 346:2002;1221-1230
-
(2002)
N Engl J Med
, vol.346
, pp. 1221-1230
-
-
Angulo, P.1
-
3
-
-
0034235208
-
Metabolic and nutritional considerations in nonalcoholic fatty liver
-
Fong D.G., Nehra V., Lindor K.D., Buchman A.I. Metabolic and nutritional considerations in nonalcoholic fatty liver. Hepatology. 32:2000;3-10
-
(2000)
Hepatology
, vol.32
, pp. 3-10
-
-
Fong, D.G.1
Nehra, V.2
Lindor, K.D.3
Buchman, A.I.4
-
6
-
-
0034791616
-
Nonalcoholic steatosis and steatohepatitis: 1. Molecular mechanism for polyunsaturated fatty acid regulation of gene transcription
-
Clarke S.D. Nonalcoholic steatosis and steatohepatitis: 1. molecular mechanism for polyunsaturated fatty acid regulation of gene transcription. Am J Physiol Gastrointest Liver Physiol. 281:2001;G865-G869
-
(2001)
Am J Physiol Gastrointest Liver Physiol
, vol.281
-
-
Clarke, S.D.1
-
7
-
-
0036712472
-
The influence of different fats on obesity. Insulin resistance and inflammation
-
Bray G.A., Lovejoy G.A., Smith S.R., Delany G.P., Lefevre M., Hwang D., et al. The influence of different fats on obesity. Insulin resistance and inflammation. J Nutr. 132:2002;2488-2491
-
(2002)
J Nutr
, vol.132
, pp. 2488-2491
-
-
Bray, G.A.1
Lovejoy, G.A.2
Smith, S.R.3
Delany, G.P.4
Lefevre, M.5
Hwang, D.6
-
8
-
-
0034613316
-
Fatty acid regulation of gene transcription
-
Duplus E., Glorian M., Forest C. Fatty acid regulation of gene transcription. J Biol Chem. 275:2000;30749-30752
-
(2000)
J Biol Chem
, vol.275
, pp. 30749-30752
-
-
Duplus, E.1
Glorian, M.2
Forest, C.3
-
9
-
-
0032814457
-
Regulation of gene expression by dietary fat
-
Jump D.B., Clarke S.D. Regulation of gene expression by dietary fat. Annu Rev Nutr. 19:1999;63-90
-
(1999)
Annu Rev Nutr
, vol.19
, pp. 63-90
-
-
Jump, D.B.1
Clarke, S.D.2
-
10
-
-
0037636366
-
The physiology of cellular liporegulation
-
Unger R.H. The physiology of cellular liporegulation. Annu Rev Physiol. 65:2003;333-347
-
(2003)
Annu Rev Physiol
, vol.65
, pp. 333-347
-
-
Unger, R.H.1
-
11
-
-
0031799747
-
Hepatic steatosis: Innocent bystander or guilty party
-
Day C.P., James O.E.W. Hepatic steatosis: innocent bystander or guilty party. Hepatology. 1998;1463-1466
-
(1998)
Hepatology
, pp. 1463-1466
-
-
Day, C.P.1
James, O.E.W.2
-
12
-
-
0037453056
-
Triglyceride accumulation protects against fatty induced lipotoxicity
-
Listberger L.L., Han X., Lewis S.E., Cases S., Farese R.V., Ory D.S., et al. Triglyceride accumulation protects against fatty induced lipotoxicity. Proc Natl Acad Sci U S A. 100:2003;3077-3082
-
(2003)
Proc Natl Acad Sci U S a
, vol.100
, pp. 3077-3082
-
-
Listberger, L.L.1
Han, X.2
Lewis, S.E.3
Cases, S.4
Farese, R.V.5
Ory, D.S.6
-
13
-
-
0031930804
-
Dietary fat, genetic predisposition and obesity. Lessons from animal models
-
West D.B., York B. Dietary fat, genetic predisposition and obesity. Lessons from animal models. Am J Clin Nutr. 67:1998;505S-512S
-
(1998)
Am J Clin Nutr
, vol.67
-
-
West, D.B.1
York, B.2
-
14
-
-
0034030876
-
High fat feeding reduces the diurnal variation of plasma leptin concentration in rats
-
Cha M.C., Chou C.J., Boozer C.N. High fat feeding reduces the diurnal variation of plasma leptin concentration in rats. Metabolism. 49:2000;503-507
-
(2000)
Metabolism
, vol.49
, pp. 503-507
-
-
Cha, M.C.1
Chou, C.J.2
Boozer, C.N.3
-
15
-
-
0026534940
-
Development of dietary obesity in rats, influence of amount and composition of dietary fat
-
Hill J.O., Lin D., Yakubu F., Peters J.C. Development of dietary obesity in rats, influence of amount and composition of dietary fat. Int J Obes Relat Metab Disord. 16:1992;321-333
-
(1992)
Int J Obes Relat Metab Disord
, vol.16
, pp. 321-333
-
-
Hill, J.O.1
Lin, D.2
Yakubu, F.3
Peters, J.C.4
-
16
-
-
0014851430
-
Dietary obesity in rats; Body weight and body fat accretion in seven strains
-
Schemmel R., Mickelson O., Gill G.L. Dietary obesity in rats; body weight and body fat accretion in seven strains. J Nutr. 100:1970;1041-1048
-
(1970)
J Nutr
, vol.100
, pp. 1041-1048
-
-
Schemmel, R.1
Mickelson, O.2
Gill, G.L.3
-
17
-
-
0036712472
-
The influence of dietary fats and fatty acids in obesity, insulins, resistance and inflammation
-
Bray G.A., Lovejoy J.C., Smith S.R., Delany J.P., Levefre M., Hwang D., et al. The influence of dietary fats and fatty acids in obesity, insulins, resistance and inflammation. J Nutr. 132:2002;2488-2491
-
(2002)
J Nutr
, vol.132
, pp. 2488-2491
-
-
Bray, G.A.1
Lovejoy, J.C.2
Smith, S.R.3
Delany, J.P.4
Levefre, M.5
Hwang, D.6
-
18
-
-
1242290584
-
Model of nonalcoholic steatohepatitis
-
Lieber S.C., Leo M.A., Mak K.M., Su Y., Cao Q., Ren C., et al. Model of nonalcoholic steatohepatitis. Am J Clin Nutr. 79:2004;502-509
-
(2004)
Am J Clin Nutr
, vol.79
, pp. 502-509
-
-
Lieber, S.C.1
Leo, M.A.2
Mak, K.M.3
Su, Y.4
Cao, Q.5
Ren, C.6
-
19
-
-
0035088211
-
Insulin resistance and mitochondrial abnormalities in NASH: A cool look at a burning issue
-
Angulo P., Lindor K.D. Insulin resistance and mitochondrial abnormalities in NASH: a cool look at a burning issue. Gastroenterology. 120:2001;1281-1285
-
(2001)
Gastroenterology
, vol.120
, pp. 1281-1285
-
-
Angulo, P.1
Lindor, K.D.2
-
20
-
-
0022496127
-
Morphological changes of organs after sucrose or fructose feeding prog
-
Poulsom R. Morphological changes of organs after sucrose or fructose feeding prog. Biochem Pharmacol. 21:1986;104-134
-
(1986)
Biochem Pharmacol
, vol.21
, pp. 104-134
-
-
Poulsom, R.1
-
21
-
-
0022538513
-
Biochemical changes in liver and blood during liver fattening in rats
-
Bogin E., Avidar Y., Meron M. Biochemical changes in liver and blood during liver fattening in rats. J Clin Chem Clin Biochem. 24:1986;621-626
-
(1986)
J Clin Chem Clin Biochem
, vol.24
, pp. 621-626
-
-
Bogin, E.1
Avidar, Y.2
Meron, M.3
-
22
-
-
4344571457
-
Hepatic steatosis enhances Fas expression and liver injury in mice [abstract]
-
Feldstein A.E., Canbay A.E., Giucciardi M.E., Higuchi H., Gores G.J. Hepatic steatosis enhances Fas expression and liver injury in mice [abstract]. Hepatology. 38:2003;192a
-
(2003)
Hepatology
, vol.38
-
-
Feldstein, A.E.1
Canbay, A.E.2
Giucciardi, M.E.3
Higuchi, H.4
Gores, G.J.5
-
24
-
-
0032862559
-
Activation of nuclear factor kappa b and cytokine imbalance in experimental alcoholic liver disease in the rat
-
Nanji A.A., Jokelainen K., Rahemtulla A., Miao L., Fogt F., Matsumoto H., et al. Activation of nuclear factor kappa b and cytokine imbalance in experimental alcoholic liver disease in the rat. Hepatology. 30:1999;934-943
-
(1999)
Hepatology
, vol.30
, pp. 934-943
-
-
Nanji, A.A.1
Jokelainen, K.2
Rahemtulla, A.3
Miao, L.4
Fogt, F.5
Matsumoto, H.6
-
25
-
-
0035665313
-
Increased severity of alcoholic liver injury in female rats: Role of oxidative stress, endotoxin and chemokines
-
Nanji A.A., Jokelainen K., Fotouhinia M., Rahemtulla A., Thomas P., Tipoe G.L., et al. Increased severity of alcoholic liver injury in female rats: role of oxidative stress, endotoxin and chemokines. Am J Physiol Gastrointest Liver Physiol. 281:2002;G1348-G1356
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.281
-
-
Nanji, A.A.1
Jokelainen, K.2
Fotouhinia, M.3
Rahemtulla, A.4
Thomas, P.5
Tipoe, G.L.6
-
26
-
-
0031059248
-
Enhanced cyclooxygenase-2 gene expression in alcoholic liver disease in the rat
-
Nanji A.A., Miao L., Thomas P., Rahemtulla A., Khwaja S., Zhao S., et al. Enhanced cyclooxygenase-2 gene expression in alcoholic liver disease in the rat. Gastroenterology. 112:1997;943-951
-
(1997)
Gastroenterology
, vol.112
, pp. 943-951
-
-
Nanji, A.A.1
Miao, L.2
Thomas, P.3
Rahemtulla, A.4
Khwaja, S.5
Zhao, S.6
-
28
-
-
0034092716
-
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
-
Leclerg L.A., Farrell G.C., Field J., Bell D.R., Gonzalez F.J., Robertson G.R. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. J Clin Invest. 105:2000;1067-1075
-
(2000)
J Clin Invest
, vol.105
, pp. 1067-1075
-
-
Leclerg, L.A.1
Farrell, G.C.2
Field, J.3
Bell, D.R.4
Gonzalez, F.J.5
Robertson, G.R.6
-
31
-
-
0038643427
-
Central Role of PPARα-dependent hepatic lipid turnover in dietary steatohepatitis in mice
-
Ip E., Farrell G.C., Robertson G.C., Hall P., Kirsch R., Leclerq I. Central Role of PPARα-dependent hepatic lipid turnover in dietary steatohepatitis in mice. Hepatology. 38:2003;123-132
-
(2003)
Hepatology
, vol.38
, pp. 123-132
-
-
Ip, E.1
Farrell, G.C.2
Robertson, G.C.3
Hall, P.4
Kirsch, R.5
Leclerq, I.6
-
33
-
-
0032538421
-
Biochemical and evolutionary significance of phospholipid methylation
-
Walkley C.J., Yu L., Agellon D.E., Vance D.E. Biochemical and evolutionary significance of phospholipid methylation. J Biol Chem. 273:1998;27043-27046
-
(1998)
J Biol Chem
, vol.273
, pp. 27043-27046
-
-
Walkley, C.J.1
Yu, L.2
Agellon, D.E.3
Vance, D.E.4
-
34
-
-
0037444811
-
Phosphakidylethanolamine N-methyltransferase (PEMT) knockout mice have hepatic steatosis and abnormal choline metabolite concentrations despite ingesting a recommended dietary intake of choline
-
Zhu X., Song J., Mar M., Edwareds L.J., Zeisel S.H. Phosphakidylethanolamine N-methyltransferase (PEMT) knockout mice have hepatic steatosis and abnormal choline metabolite concentrations despite ingesting a recommended dietary intake of choline. Biochem J. 370:2003;987-993
-
(2003)
Biochem J
, vol.370
, pp. 987-993
-
-
Zhu, X.1
Song, J.2
Mar, M.3
Edwareds, L.J.4
Zeisel, S.H.5
-
35
-
-
0035826898
-
Methionine adenosyltransferase 1a knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation
-
Lu S.C., Alvarez L., Huang Z., Chen L., An W., Corrales L., et al. Methionine adenosyltransferase 1a knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation. Proc Natl Acad Sci U S A. 89:2001;5560-5565
-
(2001)
Proc Natl Acad Sci U S a
, vol.89
, pp. 5560-5565
-
-
Lu, S.C.1
Alvarez, L.2
Huang, Z.3
Chen, L.4
An, W.5
Corrales, L.6
-
36
-
-
0036676924
-
Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1a
-
Martinez-Mantar M.L., Corrales F.J., Martinez Cruz L.A., Trevijano E.R., Huang Z., Chen L., et al. Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1a. FASEB J. 16:2002;1292-1294
-
(2002)
FASEB J
, vol.16
, pp. 1292-1294
-
-
Martinez-Mantar, M.L.1
Corrales, F.J.2
Martinez Cruz, L.A.3
Trevijano, E.R.4
Huang, Z.5
Chen, L.6
-
37
-
-
0037453055
-
Functional proteomics of nonalcoholic steatohepatitis: Mitochondrial proteins as targets of S - Adenosylmethionine
-
Santamaria E., Avila M.A., Latasa M.U., Rubio A., Martin-Duce A., Lu S.C., et al. Functional proteomics of nonalcoholic steatohepatitis: mitochondrial proteins as targets of S - adenosylmethionine. Proc Natl Acad Sci U S A. 100:2003;3065-3070
-
(2003)
Proc Natl Acad Sci U S a
, vol.100
, pp. 3065-3070
-
-
Santamaria, E.1
Avila, M.A.2
Latasa, M.U.3
Rubio, A.4
Martin-Duce, A.5
Lu, S.C.6
-
38
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human hemologue
-
Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J.M. Positional cloning of the mouse obese gene and its human hemologue. Nature. 372:1994;425-432
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
39
-
-
0034714051
-
Leptin physiology: A second look
-
Unger R.H. Leptin physiology: a second look. Regul Pept. 92:2000;87-95
-
(2000)
Regul Pept
, vol.92
, pp. 87-95
-
-
Unger, R.H.1
-
40
-
-
0033514956
-
Regulation of fatty acid homeostasis in cells: Novel role of leptin
-
Unger R.H., Zhou Y.T., Orci L. Regulation of fatty acid homeostasis in cells: novel role of leptin. Proc Natl Acad Sci U S A. 96:1999;2327-2332
-
(1999)
Proc Natl Acad Sci U S a
, vol.96
, pp. 2327-2332
-
-
Unger, R.H.1
Zhou, Y.T.2
Orci, L.3
-
41
-
-
0036182137
-
Lipotoxic diseases
-
Unger R.H. Lipotoxic diseases. Annu Rev Med. 53:2002;319-336
-
(2002)
Annu Rev Med
, vol.53
, pp. 319-336
-
-
Unger, R.H.1
-
42
-
-
0038675338
-
Hyperleptinemia precipitates diet-induced obesity in transgenic mice overexpressing leptin
-
Ogus S., Ke Y., Qiu J., Wang B., Chehab F.F. Hyperleptinemia precipitates diet-induced obesity in transgenic mice overexpressing leptin. Endocrinology. 144:2003;2866-2869
-
(2003)
Endocrinology
, vol.144
, pp. 2866-2869
-
-
Ogus, S.1
Ke, Y.2
Qiu, J.3
Wang, B.4
Chehab, F.F.5
-
43
-
-
0001513966
-
Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis
-
Yang S.Q., Lin H.Z., Lane M.D., Clemens M., Diehl A.M. Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc Natl Acad Sci U S A. 94:1997;2557-2562
-
(1997)
Proc Natl Acad Sci U S a
, vol.94
, pp. 2557-2562
-
-
Yang, S.Q.1
Lin, H.Z.2
Lane, M.D.3
Clemens, M.4
Diehl, A.M.5
-
44
-
-
0032898080
-
Mitochondrial proteins that regulate apoptosis and necrosis are induced in the mouse fatty liver
-
Rashid A., Wu T.C., Huang C.C., Chen C.H., Lin H.Z., Yang S.Q., et al. Mitochondrial proteins that regulate apoptosis and necrosis are induced in the mouse fatty liver. Hepatology. 29:1999;1131-1138
-
(1999)
Hepatology
, vol.29
, pp. 1131-1138
-
-
Rashid, A.1
Wu, T.C.2
Huang, C.C.3
Chen, C.H.4
Lin, H.Z.5
Yang, S.Q.6
-
45
-
-
0033605261
-
Obesity induces expression of uncoupling protein 2 in hepatocytes and promotes liver ATP depletion
-
Chavin K.D., Yang S.Q., Lin Z., Chatham J., Chacko V.P., Hoek J.B., et al. Obesity induces expression of uncoupling protein 2 in hepatocytes and promotes liver ATP depletion. J Biol Chem. 274:1999;5692-5700
-
(1999)
J Biol Chem
, vol.274
, pp. 5692-5700
-
-
Chavin, K.D.1
Yang, S.Q.2
Lin, Z.3
Chatham, J.4
Chacko, V.P.5
Hoek, J.B.6
-
46
-
-
0033305213
-
Peroxisome proliferator activated receptors: Nuclear control of metabolism
-
Desvergne B., Wahli W. Peroxisome proliferator activated receptors: nuclear control of metabolism. Endocr Rev. 20:1999;649-688
-
(1999)
Endocr Rev
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
47
-
-
0036293873
-
PPARs: Transcription factors controlling lipid and lipoprotein metabolism
-
Bocher V., Pineda I., Fruchart C., Staels B. PPARs: transcription factors controlling lipid and lipoprotein metabolism. Ann N Y Acad Sci. 967:2002;7-18
-
(2002)
Ann N Y Acad Sci
, vol.967
, pp. 7-18
-
-
Bocher, V.1
Pineda, I.2
Fruchart, C.3
Staels, B.4
-
48
-
-
0035658444
-
Nonalcoholic steatosis and steatohepatitis: Peroxisomal β oxidation, PPAR and steatohepatitis
-
Reddy J.K. Nonalcoholic steatosis and steatohepatitis: peroxisomal β oxidation, PPAR and steatohepatitis. Am J Physiol Gastrointest Liver Physiol. 281:2001;G1333-G1339
-
(2001)
Am J Physiol Gastrointest Liver Physiol
, vol.281
-
-
Reddy, J.K.1
-
49
-
-
0032699670
-
Peroxisome proliferator-activated receptorα mediates the adaptive response to fasting
-
Kersten S., Seydoux J., Peters J.M., Gonzalez F.J., Desvergne B., Wahli W. Peroxisome proliferator-activated receptorα mediates the adaptive response to fasting. J Clin Invest. 103:1999;1489-1498
-
(1999)
J Clin Invest
, vol.103
, pp. 1489-1498
-
-
Kersten, S.1
Seydoux, J.2
Peters, J.M.3
Gonzalez, F.J.4
Desvergne, B.5
Wahli, W.6
-
50
-
-
0033594980
-
The critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPAR_ null mouse as a model of fatty acid oxidation disorders
-
Leone T., Weinheimer C., Kelly D. The critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: the PPAR_ null mouse as a model of fatty acid oxidation disorders. Proc Natl Acad Sci U S A. 96:1999;7473-7478
-
(1999)
Proc Natl Acad Sci U S a
, vol.96
, pp. 7473-7478
-
-
Leone, T.1
Weinheimer, C.2
Kelly, D.3
-
51
-
-
0032491614
-
Peroxisome proliferator-activated receptor α isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis
-
Costet P., Legendre C., More J., Edgar A., Galtier P., Pineau T. Peroxisome proliferator-activated receptor α isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis. J Biol Chem. 273:1998;29577-29585
-
(1998)
J Biol Chem
, vol.273
, pp. 29577-29585
-
-
Costet, P.1
Legendre, C.2
More, J.3
Edgar, A.4
Galtier, P.5
Pineau, T.6
-
53
-
-
0034939632
-
Peroxisomal β oxidation and peroxisome proliferator-activated receptor-activated receptor: An adaptive metabolic system
-
Reddy J.K., Hashimoto T. Peroxisomal β oxidation and peroxisome proliferator-activated receptor-activated receptor: an adaptive metabolic system. Annu Rev Nutr. 21:2001;193-230
-
(2001)
Annu Rev Nutr
, vol.21
, pp. 193-230
-
-
Reddy, J.K.1
Hashimoto, T.2
-
54
-
-
10144234128
-
Hepatocellular and hepatic peroxisomal alternations in mice with a disrupted peroxisomal fatty acyt-coenzyme a oxidase gene
-
Fan C., Pan J., Chu R., Lee D., Kluckman D., Usuda N., et al. Hepatocellular and hepatic peroxisomal alternations in mice with a disrupted peroxisomal fatty acyt-coenzyme A oxidase gene. J Biol Chem. 271:1996;24698-24710
-
(1996)
J Biol Chem
, vol.271
, pp. 24698-24710
-
-
Fan, C.1
Pan, J.2
Chu, R.3
Lee, D.4
Kluckman, D.5
Usuda, N.6
-
55
-
-
0033516569
-
Peroxisomal and mitochondrial fatty acid β oxidation in mice nullizygous for both peroxisome proliferator-activated receptor α and peroxisomal fatty Acyl-coA Oxidase
-
Hashimoto T., Fujita T., Usuda N., Cook W., Qi C., Peters J.M., et al. Peroxisomal and mitochondrial fatty acid β oxidation in mice nullizygous for both peroxisome proliferator-activated receptor α and peroxisomal fatty Acyl-coA Oxidase. J Biol Chem. 274:1999;19228-19236
-
(1999)
J Biol Chem
, vol.274
, pp. 19228-19236
-
-
Hashimoto, T.1
Fujita, T.2
Usuda, N.3
Cook, W.4
Qi, C.5
Peters, J.M.6
-
56
-
-
0028015713
-
Peroxisome proliferator-activated receptor gamma: Adipose predominant expression and induction early in adipocyte differentiation
-
Chawla A., Shwarz E.J., Dimaculagan D.D., Lazar M.A. Peroxisome proliferator-activated receptor gamma: adipose predominant expression and induction early in adipocyte differentiation. Endocrinology. 135:1994;798-800
-
(1994)
Endocrinology
, vol.135
, pp. 798-800
-
-
Chawla, A.1
Shwarz, E.J.2
Dimaculagan, D.D.3
Lazar, M.A.4
-
58
-
-
0034052579
-
Peroxisome-proliferator-activated alpha is restricted to hepatic parenchymal cells, not kupfter cells: Implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis
-
Pekers J.M., Rusyn I., Rose M.L., Gonzalez F.J., Thurman R.G. Peroxisome-proliferator-activated alpha is restricted to hepatic parenchymal cells, not kupfter cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis. Carcinogenesis. 21:2000;823-826
-
(2000)
Carcinogenesis
, vol.21
, pp. 823-826
-
-
Pekers, J.M.1
Rusyn, I.2
Rose, M.L.3
Gonzalez, F.J.4
Thurman, R.G.5
-
59
-
-
0033695790
-
Up-regulation of peroxisome proliferator-activated receptors, PPAR-alpha and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: Troglitazone induces expression of PPAR-gamma-response adipose tissue specific genes in the liver of obese diabetic mice
-
Memon R.A. Up-regulation of peroxisome proliferator-activated receptors, PPAR-alpha and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-response adipose tissue specific genes in the liver of obese diabetic mice. Endocrinology. 141:2000;4021-4031
-
(2000)
Endocrinology
, vol.141
, pp. 4021-4031
-
-
Memon, R.A.1
-
60
-
-
0034796418
-
Hepatic overexpression of peroxisome proliferator-activated receptor gamma in the ob/ob mouse model of non-insulin dependent diabetes mellitus
-
Rahimian R., et al. Hepatic overexpression of peroxisome proliferator-activated receptor gamma in the ob/ob mouse model of non-insulin dependent diabetes mellitus. Mol Cell Biochem. 224:2001;29-37
-
(2001)
Mol Cell Biochem
, vol.224
, pp. 29-37
-
-
Rahimian, R.1
-
61
-
-
0141446024
-
Liver peroxisome proliferator-activated receptor γ clearance and regulation of body mass
-
Gavrilova O., Haluzik M., Matsuesue K., Gutson J.J., Johnson L., Dietz K.H., et al. Liver peroxisome proliferator-activated receptor γ clearance and regulation of body mass. J Biol Chem. 278:2003;34268-34276
-
(2003)
J Biol Chem
, vol.278
, pp. 34268-34276
-
-
Gavrilova, O.1
Haluzik, M.2
Matsuesue, K.3
Gutson, J.J.4
Johnson, L.5
Dietz, K.H.6
-
62
-
-
0037373008
-
Liver-specific description of PPAR γ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotype
-
Matsuesue K., Haluzik M., Lambert G., Yim S.H., Gavrilova O., Ward J.M., et al. Liver-specific description of PPAR γ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotype. J Clin Invest. 111:2003;737-747
-
(2003)
J Clin Invest
, vol.111
, pp. 737-747
-
-
Matsuesue, K.1
Haluzik, M.2
Lambert, G.3
Yim, S.H.4
Gavrilova, O.5
Ward, J.M.6
-
63
-
-
9144229185
-
Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle
-
He W., Barak Y., Hevener A., Olson K., Liao D., Le J., et al. Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle. Proc Natl Acad Sci U S A. 100:2003;15712-15717
-
(2003)
Proc Natl Acad Sci U S a
, vol.100
, pp. 15712-15717
-
-
He, W.1
Barak, Y.2
Hevener, A.3
Olson, K.4
Liao, D.5
Le, J.6
-
64
-
-
0032892175
-
Sterolan regulatory element binding proteins; Activation of cholesterol and fatty acid biosynthesis
-
Horton J.D., Shimomura I. Sterolan regulatory element binding proteins; activation of cholesterol and fatty acid biosynthesis. Curr Opin Lipidol. 10:1999;143-150
-
(1999)
Curr Opin Lipidol
, vol.10
, pp. 143-150
-
-
Horton, J.D.1
Shimomura, I.2
-
66
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis
-
Horton J.D., Goldstein J.L., Brown M.S. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis. J Clin Invest. 109:2002;1125-1131
-
(2002)
J Clin Invest
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
67
-
-
0029797604
-
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice overexpressing truncated SREBP-1a
-
Shimano H., Horton J.D., Hammer R.E., Shimomura I., Brown M.S., Goldstein J.L. Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice overexpressing truncated SREBP-1a. J Clin Invest. 98:1996;1575-1584
-
(1996)
J Clin Invest
, vol.98
, pp. 1575-1584
-
-
Shimano, H.1
Horton, J.D.2
Hammer, R.E.3
Shimomura, I.4
Brown, M.S.5
Goldstein, J.L.6
-
68
-
-
0032567445
-
Nuclear sterol regulatory binding proteins activate genes for entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver
-
Shimonura I., Shimano H., Korn B.S., Bashmaleov Y., Horton J.D. Nuclear sterol regulatory binding proteins activate genes for entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver. J Biol Chem. 273:1998;35299-35306
-
(1998)
J Biol Chem
, vol.273
, pp. 35299-35306
-
-
Shimonura, I.1
Shimano, H.2
Korn, B.S.3
Bashmaleov, Y.4
Horton, J.D.5
-
69
-
-
0030907175
-
Isoform 1c of sterol regulatory element binding protein is less active than isoform la in livers of transgenic mice and in cultured cells
-
Shimano H., Horton J.D., Shimomura I., Hammer R.E., Brown M.S., Goldstein J.L. Isoform 1c of sterol regulatory element binding protein is less active than isoform la in livers of transgenic mice and in cultured cells. J Clin Invest. 99:1997;846-854
-
(1997)
J Clin Invest
, vol.99
, pp. 846-854
-
-
Shimano, H.1
Horton, J.D.2
Shimomura, I.3
Hammer, R.E.4
Brown, M.S.5
Goldstein, J.L.6
-
70
-
-
0033570119
-
Increased levels of nuclear SREBP-1c associated with fatty livers in two mice models of diabetes mellitus
-
Shimomura I., Bashmakov Y., Horton J.D. Increased levels of nuclear SREBP-1c associated with fatty livers in two mice models of diabetes mellitus. J Biol Chem. 274:1999;30028-30032
-
(1999)
J Biol Chem
, vol.274
, pp. 30028-30032
-
-
Shimomura, I.1
Bashmakov, Y.2
Horton, J.D.3
-
71
-
-
0032104180
-
Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2
-
Horton J.D., Shimomura I., Brown M.S., Hammer R.E., Goldstein J., Shimano H. Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2. J Clin Invest. 101:1998;2331-2339
-
(1998)
J Clin Invest
, vol.101
, pp. 2331-2339
-
-
Horton, J.D.1
Shimomura, I.2
Brown, M.S.3
Hammer, R.E.4
Goldstein, J.5
Shimano, H.6
-
72
-
-
0030840464
-
Stats and gene regulation
-
Darnell J.E. Stats and gene regulation. Science. 277:1997;1630-1635
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell, J.E.1
-
73
-
-
0030833570
-
Requirement of STAT 5b for sexual dimorphism of body growth rats and liver gene expression
-
Udy G.B., Towers R.P., Snell R.G., Wilkin R.J., Parks S., Ram P.A., et al. Requirement of STAT 5b for sexual dimorphism of body growth rats and liver gene expression. Proc Natl Acad Sci U S A. 94:1997;7239-7244
-
(1997)
Proc Natl Acad Sci U S a
, vol.94
, pp. 7239-7244
-
-
Udy, G.B.1
Towers, R.P.2
Snell, R.G.3
Wilkin, R.J.4
Parks, S.5
Ram, P.A.6
-
74
-
-
0032716979
-
STAT 5b mediates the GH-induced expression of SOCS-2 and SOCS-3mRNA in the liver
-
Davey H.W., McLachlan M.J., Wilkins R.J., Hilton D.J., Adams T.E. STAT 5b mediates the GH-induced expression of SOCS-2 and SOCS-3mRNA in the liver. Mol Cell Endocrinol. 158:1999;111-117
-
(1999)
Mol Cell Endocrinol
, vol.158
, pp. 111-117
-
-
Davey, H.W.1
McLachlan, M.J.2
Wilkins, R.J.3
Hilton, D.J.4
Adams, T.E.5
-
75
-
-
0037108907
-
A novel transgenic line of mice exhibiting autosomal recessive male-specific lethality and nonalcoholic fatty liver disease
-
Sollars V.E., McEntice B.J., Engiles J.B., Rolkstein J.L., Buchberg A.M. A novel transgenic line of mice exhibiting autosomal recessive male-specific lethality and nonalcoholic fatty liver disease. Hum Mol Genet. 11:2002;2777-2786
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2777-2786
-
-
Sollars, V.E.1
McEntice, B.J.2
Engiles, J.B.3
Rolkstein, J.L.4
Buchberg, A.M.5
-
76
-
-
0032126633
-
Hox 9 transforms primary bone marrow cells through specific collaboration with Meis 1a but not Pbδclb
-
Kroon F., Krosl J., Thorsteinsclottir U., Baban S., Buchberg A.M., Sauvageau G. Hox 9 transforms primary bone marrow cells through specific collaboration with Meis 1a but not Pbδclb. EMBO J. 17:1998;3714-3725
-
(1998)
EMBO J
, vol.17
, pp. 3714-3725
-
-
Kroon, F.1
Krosl, J.2
Thorsteinsclottir, U.3
Baban, S.4
Buchberg, A.M.5
Sauvageau, G.6
-
78
-
-
0029127584
-
Inhibition of mitochondrial β oxidation as a mechanism of hepatotoxicity
-
Fromenty B., Pessayre D. Inhibition of mitochondrial β oxidation as a mechanism of hepatotoxicity. Pharmacol Ther. 67:1995;101-154
-
(1995)
Pharmacol Ther
, vol.67
, pp. 101-154
-
-
Fromenty, B.1
Pessayre, D.2
-
79
-
-
0032927776
-
Apolipoprotein β in the Rough endoplasmic reticulum: Translation. Translocation and the initiation of lipoprotein assembly
-
Shellness G.S., Ingram M.F., Huang X.F., DeLozier J.A. Apolipoprotein β in the Rough endoplasmic reticulum: translation. Translocation and the initiation of lipoprotein assembly. J Nutr. 129:1999;456S-462S
-
(1999)
J Nutr
, vol.129
-
-
Shellness, G.S.1
Ingram, M.F.2
Huang, X.F.3
Delozier, J.A.4
-
80
-
-
0038643426
-
Inhibition of microsomal triglyceride transfer protein: Another mechanism for drug-induced steatosis in mice
-
Letteron P., Sutton A., Mansouri A., Fromenty B., Pessayre D. Inhibition of microsomal triglyceride transfer protein: another mechanism for drug-induced steatosis in mice. Hepatology. 38:2003;133-140
-
(2003)
Hepatology
, vol.38
, pp. 133-140
-
-
Letteron, P.1
Sutton, A.2
Mansouri, A.3
Fromenty, B.4
Pessayre, D.5
-
81
-
-
0344349000
-
Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice
-
Raabe M., Veniant M.M., Sullivan M.A., Zlot C.H., Bjorkegren J., Nielsen L.B., et al. Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice. J Clin Invest. 103:1999;1287-1298
-
(1999)
J Clin Invest
, vol.103
, pp. 1287-1298
-
-
Raabe, M.1
Veniant, M.M.2
Sullivan, M.A.3
Zlot, C.H.4
Bjorkegren, J.5
Nielsen, L.B.6
-
82
-
-
0027428820
-
Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinemia
-
Sharp D., Blinderman L., Combs K.A., Kienzle B., Ricci B., Wager-Smith K., et al. Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinemia. Nature. 365:1993;65-69
-
(1993)
Nature
, vol.365
, pp. 65-69
-
-
Sharp, D.1
Blinderman, L.2
Combs, K.A.3
Kienzle, B.4
Ricci, B.5
Wager-Smith, K.6
-
83
-
-
18244365866
-
Hepatitis virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: A model of viral-related steatosis
-
Perlemuter G., Sabile A., Letteron P., Vona G., Topilko A., Samson-Bouma M.E., et al. Hepatitis virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis. FASEB J. 16:2002;185-194
-
(2002)
FASEB J
, vol.16
, pp. 185-194
-
-
Perlemuter, G.1
Sabile, A.2
Letteron, P.3
Vona, G.4
Topilko, A.5
Samson-Bouma, M.E.6
-
84
-
-
0023874587
-
Sodium valproate inhibits the movement of secretory vesicles in rat hepatocytes
-
Bellringer M.E., Rahman K., Coleman R. Sodium valproate inhibits the movement of secretory vesicles in rat hepatocytes. Biochem J. 249:1988;513-519
-
(1988)
Biochem J
, vol.249
, pp. 513-519
-
-
Bellringer, M.E.1
Rahman, K.2
Coleman, R.3
-
85
-
-
0034964992
-
The biologically active isomers of conjugated linoleic acid
-
Pariza M.W., Park Y., Cook M.E. The biologically active isomers of conjugated linoleic acid. Prog Lipid Res. 40:2001;283-296
-
(2001)
Prog Lipid Res
, vol.40
, pp. 283-296
-
-
Pariza, M.W.1
Park, Y.2
Cook, M.E.3
-
86
-
-
0037494961
-
Association of liver steatosis with lipid oversecretion and hypotriglyceridemia in C57BL/6j mice fed trans-10, Cis-12 linoleic acid
-
DeGrace P., Demizieux L., Gresti J., Chardigny J., Sebedio J., Clouet P. Association of liver steatosis with lipid oversecretion and hypotriglyceridemia in C57BL/6j mice fed trans-10, Cis-12 linoleic acid. FEBS Lett. 546:2003;335-339
-
(2003)
FEBS Lett
, vol.546
, pp. 335-339
-
-
Degrace, P.1
Demizieux, L.2
Gresti, J.3
Chardigny, J.4
Sebedio, J.5
Clouet, P.6
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