Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver

Journal of Biological Chemistry

Volumn 273, Issue 52, 1998, Pages 35299-35306

  Shimomura, Iichiro ^a   Shimano, Hitoshi ^a   Korn, Bobby S ^a   Bashmakov, Yuriy ^a   Horton, Jay D ^a,b  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A; ACETYL COENZYME A CARBOXYLASE; ACYL COENZYME A DESATURASE; ADENOSINE TRIPHOSPHATE CITRATE LYASE; FATTY ACID SYNTHASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; MESSENGER RNA; PHOSPHOGLUCONATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; STEROL REGULATORY ELEMENT BINDING PROTEIN;

ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; FATTY ACID SYNTHESIS; GENE ACTIVATION; GENE OVEREXPRESSION; LIVER METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; ATP CITRATE (PRO-S)-LYASE; BODY WEIGHT; CCAAT-ENHANCER-BINDING PROTEINS; CHOLESTEROL; DNA-BINDING PROTEINS; FATTY ACIDS, MONOUNSATURATED; FATTY ACIDS, UNSATURATED; GENE EXPRESSION REGULATION; GLUCOSEPHOSPHATE DEHYDROGENASE; HUMANS; LIVER; MALATE DEHYDROGENASE; MALE; MICE; MICE, TRANSGENIC; NADP; NUCLEAR PROTEINS; OLEIC ACID; ORGAN SIZE; PALMITIC ACID; PHOSPHOGLUCONATE DEHYDROGENASE; PROTEIN ISOFORMS; STEAROYL-COA DESATURASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSCRIPTION FACTORS; TRIGLYCERIDES;

ANIMALIA; MUS MUSCULUS; RODENTIA;

EID: 0032567445     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.52.35299     Document Type: Article

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