Phosphatidylethanolamine N-methyltransferase (PEMT) knockout mice have hepatic steatosis and abnormal hepatic choline metabolite concentrations despite ingesting a recommended dietary intake of choline

Biochemical Journal

Volumn 370, Issue 3, 2003, Pages 987-993

  Zhu, Xiaonan ^a   Song, Jiannan ^a   Mar, Mei Heng ^a   Edwards, Lloyd J ^b   Zeisel, Steven H ^a  

^a University of North Carolina   (United States)

^b IL   (United States)

Author keywords

Betaine; Choline deficiency; Liver steatosis; Phosphatidylcholine; Phosphocholine

Indexed keywords

CATALYSIS; ENZYMES; GENES; MOLECULAR BIOLOGY;

POSITIVE CELLS;

AMINES;

CHOLINE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLETHANOLAMINE METHYLTRANSFERASE; PHOSPHORYLCHOLINE;

AMINO ACID METABOLISM; ANIMAL MODEL; ARTICLE; CATALYSIS; CONTROLLED STUDY; DIETARY INTAKE; ENZYME ACTIVITY; FATTY LIVER; FEMALE; KNOCKOUT MOUSE; LIVER DISEASE; METABOLITE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; CHOLINE; DIET; DNA FRAGMENTATION; FATTY LIVER; FEMALE; HUMANS; IN SITU NICK-END LABELING; LIVER; MALE; METHYLTRANSFERASES; MICE; MICE, KNOCKOUT; PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE; PREGNANCY; TRIGLYCERIDES;

ANIMALIA;

EID: 0037444811     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021523     Document Type: Article

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