Translational aspects of pharmacological research into anxiety disorders: The stress-induced hyperthermia (SIH) paradigm

European Journal of Pharmacology

Volumn 585, Issue 2-3, 2008, Pages 407-425

  Vinkers, Christiaan H ^a   van Bogaert, Meg J V ^a   Klanker, Marianne ^a   Korte, S Mechiel ^a   Oosting, Ronald ^a   Hanania, Taleen ^b   Hopkins, Seth C ^c   Olivier, Berend ^a,b,d   Groenink, Lucianne ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b PSYCHOGENICS INC   (United States)

^c SUNOVION PHARMACEUTICALS INC   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

5 HT1A; 5 HT1A knockout; Anxiety; Anxiolytic; Autonomic nervous system; Body temperature; Emotional fever; GABAA; GABAA alpha subunit; IL 1 ; SIH; Strain; Stress; Stress induced hyperthermia; Thermoregulation; Translational animal model

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ANXIOLYTIC AGENT; BENZODIAZEPINE; DIAZEPAM; FLESINOXAN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; ZOLPIDEM;

ANXIETY DISORDER; DRUG EFFICACY; FEVER; HYPERTHERMIA; NONHUMAN; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; REVIEW; SEX DIFFERENCE; STRESS; TELEMETRY; THERMOREGULATION;

ANIMALS; ANXIETY DISORDERS; BODY TEMPERATURE REGULATION; DISEASE MODELS, ANIMAL; FEMALE; FEVER; HUMANS; MALE; RECEPTORS, GABA-A; SEROTONIN; SPECIES SPECIFICITY; STRESS, PSYCHOLOGICAL;

EID: 43049096745     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.02.097     Document Type: Review

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