Chemical stimulation of the dorsomedial hypothalamus evokes non-shivering thermogenesis in anesthetized rats

Brain Research

Volumn 928, Issue 1-2, 2002, Pages 113-125

  Zaretskaia, Maria V ^a   Zaretsky, Dmitry V ^a   Shekhar, Anantha ^a   DiMicco, Joseph A ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

ACTH; Bicuculine; Body temperature; Brown fat; GABA; Hypothalamus; Propranol

Indexed keywords

BICUCULLINE METHIODIDE; CORTICOTROPIN; PROPRANOLOL;

ANIMAL EXPERIMENT; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN NERVE CELL; BROWN ADIPOSE TISSUE; CONSCIOUSNESS; CONTROLLED STUDY; CORE TEMPERATURE; CORTICOTROPIN BLOOD LEVEL; DOSE RESPONSE; DRUG EFFECT; HEART RATE; HYPOTHALAMUS; LOCOMOTION; MALE; MICROINJECTION; NONHUMAN; NONSHIVERING THERMOGENESIS; PRIORITY JOURNAL; RAT; RECTUM TEMPERATURE; TELEMETRY; THALAMUS MIDLINE NUCLEUS;

ADIPOSE TISSUE, BROWN; ADRENAL MEDULLA; ADRENERGIC BETA-ANTAGONISTS; ADRENOCORTICOTROPIC HORMONE; ANIMALS; BICUCULLINE; BLOOD PRESSURE; BODY TEMPERATURE; DORSOMEDIAL HYPOTHALAMIC NUCLEUS; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; HEART RATE; MALE; MOTOR ACTIVITY; NEURAL INHIBITION; NEURONS; PROPRANOLOL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, GABA-A; SYMPATHETIC NERVOUS SYSTEM; THERMOGENESIS;

EID: 0037154866     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)03369-8     Document Type: Article

References (59)

1. Stimulation of the paraventricular nucleus with glutamate activates interscapular brown adipose tissue thermogenesis in rats
2. Intra-ventromedial hypothalamic injection of glutamate stimulates brown adipose tissue thermogenesis in the rat
3. Activation of brown adipose tissue thermogenesis by chemical stimulation of the posterior hypothalamus
4. Injection of prostaglandin E2 into the anterior hypothalamic preoptic area activates brown adipose tissue thermogenesis in the rat
5. Role of β1-and β3-adrenoceptors in the regulation of lipolysis and thermogenesis in rat brown adipocytes
6. Chemical stimulation of the dorsomedial hypothalamus elevates plasma ACTH in conscious rats
7. The dorsomedial hypothalamic nucleus revisited: 1998 Update
8. Stress hyperthermia: Physiological arguments that it is a fever
9. Adrenergic fibers in brown fat of cold-acclimated rats
10. Hypothalamic sites mediating cardiovascular effects of microinjected bicuculline and EAAs in rats
11. The nitric oxide pathway is an important modulator of stress-induced fever in rats
12. Two sympathetic nerve supplies to brown adipose tissue of the rat
13. Evidence for GABAergic inhibition of a hypothalamic sympathoexcitatory mechanism in anesthetized rats
14. Role of dorsomedial hypothalamus in the cardiovascular response to stress
15. Stimulation of metabotropic glutamate receptors in the dorsomedial hypothalamus elevates heart rate in rats
16. B receptors in the dorsomedial hypothalamus and heart rate in anesthetized rats
17. Coupling of signals to brown fat: α-and β-adrenergic responses in intact rats
18. Brown adipose tissue thermogenesis induced by low level electrical stimulation of hypothalamus in rats
19. Contribution of brown adipose tissue to central PGE1-evoked hyperthermia in rats
20. Brown adipose tissue thermogenesis is activated by electrical and chemical (L-glutamate) stimulation of the ventromedial hypothalamic nucleus in cold-acclimated rats
21. Hypothalamic control of brown adipose tissue in Zucker lean and obese rats. Effect of electrical stimulation of the ventromedial nucleus and other hypothalamic centers
22. Anteroventral third ventricle lesion suppresses fever, but not stress-induced hyperthermia in rats
23. The central efferent mechanism of brown adipose tissue thermogenesis induced by preoptic cooling
24. Alterations in behavioral responses to stressors following excitotoxin lesions of dorsomedial hypothalamic regions
25. Ventromedial hypothalamic regulation of brown adipose tissue
26. Alarm pheromone enhances stress-induced hyperthermia in rats
27. Further evidence that stress hyperthermia is a fever
28. CGRP microinjection into the ventromedial or dorsomedial hypothalamic nucleus activates heat production
29. Sympathoadrenal system and regulation of thermogenesis
30. Brown adipose tissue and thermogenesis in hypophysectomized rats in relation to temperature acclimation
31. Long term fluoxetine, but not desipramine, inhibits the ACTH and oxytocin response to the 5-HT1A agonist, 8-OH-DPAT, in male rats
32. Injection of muscimol into posterior hypothalamus blocks stress-induced tachycardia
33. Sympathetic denervation impairs responses of brown adipose tissue to VMH stimulation
34. Injection of muscimol in the posterior hypothalamus reduces the PGE1-hyperthermia in the rat
35. GABA-mediated inhibition of raphe pallidus neurons regulates sympathetic outflow to brown adipose tissue
36. Effects of α- and β-adrenergic antagonists on rise in body temperature induced by psychological stress in rats
37. Thermogenic mechanisms in brown fat
38. The uncoupling protein, thermogenin
39. Stress-induced hyperthermia in the 5-HT(1A) receptor knockout mouse is normal
40. Activation of brown adipose tissue thermogenesis by the ventromedial hypothalamus
41. Which elements are excited in electrical stimulation of mammalian central nervous system: A review
42. A comparative survey of brown fat in the neck and axilla of mammals at birth
43. Tachycardia evoked by disinhibition of the dorsomedial hypothalamus in rats is mediated through medullary raphe
44. Neurobiological basis of fever
45. Control of brown fat thermogenesis by the sympathetic nervous system
46. Defense reaction elicited by injection of GABA antagonists and synthesis inhibitors into the posterior hypothalamus in rats
47. Contribution of nonshivering thermogenesis to stress-induced hyperthermia in rats
48. A and excitatory amino acid receptors in dorsomedial hypothalamus and heart rate in rats
49. Hypothalamic excitatory amino acid receptors mediate stress-induced tachycardia in rats
50. The inhibition of nitric oxide synthase suppresses LPS-and psychological-stress-induced fever in rats
51. Effects of microinjection of muscimol into the dorsomedial or paraventricular hypothalamic nucleus on air stress-induced neuroendocrine and cardiovascular changes in rats
52. Muscimol acts in dorsomedial but not paraventricular hypothalamic nucleus to suppress cardiovascular effects of stress
53. Brown adipose tissue as a source of heat during pyrogen-induced fever
54. The projections of the dorsomedial hypothalamic nucleus in the rat
55. Brown adipose tissue thermogenesis evoked by medial preoptic stimulation is mediated via the ventromedial hypothalamic nucleus
56. Hypothalamic GABA suppresses sympathetic outflow to the cardiovascular system
57. 2) into the median preoptic area (MPOA)
58. α1-adrenergic stimulation potentiates the thermogenic action of β3-adrenoreceptor-generated cAMP in brown fat cells