Contrasting phenotypes of C57BL/6JOlaHsd, 129S2/SvHsd and 129/SvEv mice in two exploration-based tests of anxiety-related behaviour

Physiology and Behavior

Volumn 77, Issue 2-3, 2002, Pages 301-310

  Rodgers, R J ^a   Boullier, E ^a   Chatzimichalaki, P ^a   Cooper, G D ^a   Shorten, A ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Ethological analysis; Genetic background; Inbred strains; Light dark exploration; Locomotor activity; Plus maze; Risk assessment

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; DARKNESS; ETHOLOGY; EXPLORATORY BEHAVIOR; INBRED STRAIN; KNOCKOUT MOUSE; LIGHT EXPOSURE; MALE; MAZE TEST; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

EID: 0036853662     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(02)00856-9     Document Type: Article

References (65)

1. Anagnostopoulos A.V., Mobraaten L.E., Sharp J.J., Davisson M.T. Transgenic and knockout databases: behavioral profiles of mouse mutants. Physiol. Behav. 73:2001;675-689.
2. Nelson R.J., Young K.A. Behavior in mice with targeted disruption of single genes. Neurosci. Biobehav. Rev. 22:1998;453-462.
3. Crawley J.N. What's wrong with my mouse? Behavioral phenotyping of transgenic and knockout mice. 2000;Wiley-Liss, New York.
4. Gingrich J.A., Hen R. Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice. Psychopharmacology. 155:2001;1-10.
5. Crabbe J.C., Wahlsten D., Dudek B.C. Genetics of mouse behavior: interactions with laboratory environment. Science. 284:1999;1670-1672.
6. McIlwain K.L., Merriweather M.Y., Yuva-Paylor L.A., Paylor R. The use of behavioral test batteries: effects of training history. Physiol. Behav. 73:2001;705-717.
7. Wahlsten D. Standardizing tests of mouse behavior: reasons, recommendations, and reality. Physiol. Behav. 73:2001;695-704.
8. Gingrich J.A., Hen R. The broken mouse: the role of development, plasticity and environment in the interpretation of phenotypic changes in knockout mice. Curr. Opin. Neurobiol. 10:2000;146-152.
9. 1B receptors in the mouse. J. Pharmacol. Exp. Ther. 298:2001;1092-1100.
10. Crawley J.N. Unusual behavioral phenotypes of inbred mouse strains. Trends Neurosci. 19:1996;181-182.
11. Gerlai R. Gene-targeting studies of mammalian behavior: is it the mutation or the genetic background? Trends Neurosci. 19:1996;177-178.
12. Crawley J.N., Paylor R. A proposed test battery and constellations of specific behavioral paradigms to investigate the behavioral phenotypes of transgenic and knockout mice. Horm. Behav. 31:1997;197-211.
13. Phillips T.J., Hen R., Crabbe J.C. Complications associated with genetic background effects in research using knockout mice. Psychopharmacology. 147:1999;5-7.
14. Rogers D.C., Jones D.N.C., Nelson P.R., Jones C.M., Quilter C.A., Robinson T.L., Hagan J.J. Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains. Behav. Brain Res. 105:1999;207-217.
15. Tarantino L.M., Gould T.J., Druham J.P., Bucan M. Behavior and mutagenesis screens: the importance of baseline analysis of inbred strains. Mamm. Genome. 11:2000;555-564.
16. Gerlai R. Gene targeting: technical confounds and potential solutions in behavioral brain research. Behav. Brain Res. 125:2001;13-21.
17. Homanics G.E., Quinlan J.J., Firestone L.L. Pharmacologic and behavioral responses of inbred C57BL/6J and strain 129/SvJ mouse lines. Pharmacol. Biochem. Behav. 63:1999;21-26.
18. A receptor are more sensitive to benzodiazepines. Pharmacol. Biochem. Behav. 66:2000;371-374.
19. Contet C., Rawlins J.N.P., Deacon R.M.J. A comparison of 129S2/SvHsd and C57BL/6JOlaHsd mice on a test battery assessing sensorimotor, affective and cognitive behaviours: implications for the study of genetically-modified mice. Behav. Brain Res. 124:2001;33-46.
20. 1A receptor mutant mice. Proc. Natl. Acad. Sci. U.S.A. 95:1998;15049-15054.
21. A-receptor clustering results in enhanced anxiety and a bias for threat cues. Nat. Neurosci. 2:1999;833-839.
22. Holmes A. Targeted gene mutation approaches to the study of anxiety-like behavior in mice. Neurosci. Biobehav. Rev. 25:2001;261-273.
23. Belzung C., Griebel G. Measuring normal and pathological anxiety-like behaviour in mice: a review. Behav. Brain Res. 125:2001;141-149.
24. Thompson W.R. The inheritance of behavior: behavioral differences in fifteen mouse strains. Can. J. Psychol. 7:1953;145-155.
25. Sudak H.S., Maas J.W. Central nervous system serotonin and norepinephrine localization in emotional and non-emotional strains of mice. Nature. 201:1964;1254-1256.
26. Crawley J.N., Davis L.G. Baseline exploratory activity predicts anxiolytic responsiveness to diazepam in five mouse strains. Brain Res. Bull. 8:1982;609-612.
27. Trullas R., Skolnick P. Differences in fear motivated behaviors among inbred mouse strains. Psychopharmacology. 111:1993;323-331.
28. Beuzen A., Belzung C. Link between emotional memory and anxiety states: a study by principal components analysis. Physiol. Behav. 58:1995;111-118.
29. Belzung C., Le Guisquet A.M., Crestani F. Flumazenil induces benzodiazepine partial agonist-like effects in BALB/c but not C57BL/6 mice. Psychopharmacology. 148:2000;24-32.
30. Griebel G., Belzung C., Perrault G., Sanger D.J. Differences in anxiety-related behaviors and in sensitivity to diazepam in inbred and outbred strains of mice. Psychopharmacology. 148:2000;164-170.
31. Lepicard E.M., Joubert C., Hagneau I., Perez-Diaz F., Chapouthier G. Differences in anxiety-related behavior and response to diazepam in BALB/cByJ and C57BL/6J strains of mice. Pharmacol. Biochem. Behav. 67:2000;739-748.
32. Van Gaalen M.M., Steckler T. Behavioural analysis of four mouse strains in an anxiety test battery. Behav. Brain Res. 115:2000;95-106.
33. Ohl F., Sillaber I., Binder E., Keck M.E., Holsboer F. Differential analysis of behavior and diazepam-induced alterations in C57BL/6N and BALB/c mice using the modified hole-board test. J. Psychiat. Res. 35:2001;147-154.
34. Crawley J.N., Belknap J.K., Collins A., Crabbe J.C., Frankel W., Henderson N., Hitzemann R.J., Maxson S.C., Miner L.L., Silva A.J., Wehner J.M., Wynshaw-Boris A., Paylor R. Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies. Psychopharmacology. 132:1997;107-124.
35. Anisman H., Hayley S., Kelly O., Borowski T., Merlai Z. Psychogenic, neurogenic, and systemic stressor effects on plasma corticosterone and behavior: mouse strain-dependent outcomes. Behav. Neurosci. 115:2001;443-454.
36. Agmo A., Belzung C., Deloire X., Grassin M., Lewis S. Blockade of anxiolytic-like actions of chlordiazepoxide by naloxone in the elevated plus-maze: comparisons between Swiss, C57BL/6 and BALB/c mice. Psychobiology. 27:1999;105-113.
37. Simpson E.M., Linder C.C., Sargent E.E., Davisson M.T., Mobraaten L.E., Sharp J.J. Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice. Nat. Genet. 16:1997;19-27.
38. Gould T.J., Wehner J.M. Genetic influences on latent inhibition. Behav. Neurosci. 113:1999;1291-1296.
39. Bolivar V.J., Caldarone B.J., Reilly A.A., Flaherty L. Habituation of activity in an open field: a survey of inbred strains and F1 hybrids. Behav. Genet. 30:2000;285-293.
40. Carter T.A., Del Rio J.A., Greenhall J.A., Latronica M.L., Lockhart D.J., Barlow C. Chipping away at complex behavior: transcriptome/phenotype correlations in the mouse brain. Physiol. Behav. 73:2001;849-857.
41. Cook M.N., Williams R.W., Flaherty L. Anxiety-related behaviors in the elevated zero-maze are affected by genetic factors and retinal degeneration. Behav. Neurosci. 115:2001;468-476.
42. Voikar V., Koks S., Vasar E., Rauvala H. Strain and gender differences in the behavior of mouse lines commonly used in transgenic studies. Physiol. Behav. 72:2001;271-281.
43. Holmes A., Wrenn C.C., Harris A.P., Thayer K.E., Crawley J.N. Behavioral profiles of inbred strians on novel olfactory, spatial and emotional tests for reference memory in mice. Genes, Brain Behav. 1:2002;55-69.
44. Lister R.G. The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology. 92:1987;180-185.
45. Rodgers R.J., Shepherd J.K. Influence of prior maze experience on behaviour and response to diazepam in the elevated plus-maze and light/dark tests of anxiety in mice. Psychopharmacology. 113:1993;237-242.
46. Holmes A., Rodgers R.J. Responses of Swiss-Webster mice to repeated plus-maze experience: further evidence for a qualitative shift in emotional state? Pharmacol. Biochem. Behav. 60:1998;473-488.
47. Holmes A., Iles J.P., Mayell S.J., Rodgers R.J. Prior test experience compromises the anxiolytic efficacy of chlordiazepoxide in the mouse light/dark exploration test. Behav. Brain Res. 122:2001;159-167.
48. Rodgers R.J., Chatzimichalaki P., Cooper G.D. Behavioural phenotyping of C57BL/6J, 129/SvEv and 129/SvHsd mice in the light/dark exploration test of anxiety. J. Psychopharmacol. 15:2001;D28. Suppl.
49. Rodgers R.J., Boullier E.R., Shorten A.L. 'Parental' anxiety in the plus-maze: implications for KO research. Behav. Pharmacol. 12(Suppl 1):2001;S85.
50. Weiss SM. Pharmacological and behavioural examination of the defensive reactions of laboratory mice to the calls of the Tawny Owl. PhD Thesis, University of Leeds, 1995.
51. Rodgers R.J., Cole J.C. Influence of social isolation, gender, strain and prior novelty on plus-maze behaviour in mice. Physiol. Behav. 54:1993;729-736.
52. Treit D., Menard J., Royan C. Anxiogenic stimuli in the elevated plus-maze. Pharmacol. Biochem. Behav. 44:1993;463-469.
53. Treit D., Fundytus M. Thigmotaxis as a test for anxiolytic activity in rats. Pharmacol. Biochem. Behav. 31:1989;959-962.
54. Kelly M.A., Rubinstein M., Phillips T.J., Lessov C.N., Burkhart-Kasch S., Zhang G., Bunzow J.R., Fang Y., Gerhardt G.A., Grandy D.K., Low M.J. Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage, genetic background, and developmental adaptations. J. Neurosci. 18:1998;3470-3479.
55. Le Roy I., Pothian S., Mortaud S., Chabert C., Nicolas L., Cherfouth A., Roubertoux P.L. Loss of aggression, after transfer onto a C57BL/6J background, in mice carrying a targeted disruption of the neuronal nitric oxide synthase gene. Behav. Genet. 30:2000;367-373.
56. Balogh S.A., McDowell C.S., Stavnezer A.J., Denenberg V.H. A behavioral and neuroanatomical assessment of an inbred substrain of 129 mice with behavioral comparisons to C57BL/6J mice. Brain Res. 836:1999;38-48.
57. Mogil J.S., Yu L., Basbaum A.I. Pain genes? Natural variation and transgenic mutants. Annu. Rev. Neurosci. 23:2000;777-811.
58. Montowski A., Poettig M., Mederer A., Holsboer F. Behavioural performance in three substrains of mouse strain 129. Brain Res. 762:1997;12-18.
59. Blanchard R.J., Yudko E.B., Rodgers R.J., Blanchard D.C. Defense system psychopharmacology: an ethological approach to the pharmacology of fear and anxiety. Behav. Brain Res. 58:1993;155-165.
60. 1A receptor antagonists on plus-maze behaviour in mice: II. WAY-100635, SDZ 216-525 and NAN-190. Pharmacol. Biochem. Behav. 58:1997;593-603.
61. A receptor binding, and benzodiazepine-resistant anxiety. J. Neurosci. 20:2000;2758-2765.
62. 1A receptor knockout mouse and anxiety. Behav. Pharmacol. 12:2001;439-450.
63. Rodgers R.J. Anxious genes, emerging themes. Behav. Pharmacol. 12:2001;471-476.
64. Belzung C. The genetic basis of the pharmacological effects of anxiolytics: a review based on rodents. Behav. Pharmacol. 12:2001;451-460.
65. Rodgers RJ, Davies B, Shore R. Absence of anxiolytic response to chlordiazepoxide in two common genetic background strains (C57BL/6JOlaHsd and 129S2/SvHsd) exposed to the elevated plus-maze. Submitted.