메뉴 건너뛰기




Volumn 282, Issue 1, 1997, Pages 162-171

Carrier-mediated hepatic uptake of quinolone antibiotics in the rat

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CIMETIDINE; CIPROFLOXACIN; ENOXACIN; GREPAFLOXACIN; LOMEFLOXACIN; OFLOXACIN; OPC 17203; OUABAIN; PRAVASTATIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

EID: 0030824648     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (43)

References (53)
  • 1
    • 0016355478 scopus 로고
    • A new look at the statistical model identification
    • AKAIKE, H.: A new look at the statistical model identification. IEEE Trans. Automat. Contr. 19: 716-723, 1974.
    • (1974) IEEE Trans. Automat. Contr. , vol.19 , pp. 716-723
    • Akaike, H.1
  • 2
    • 0029094613 scopus 로고
    • Pharmacokinetics of grepafloxacin (IV): Metabolism after oral administration of grepafloxacin in rats, monkeys and humans
    • AKIYAMA, H., KOIKE, M., KYUUSHIKI, K., SUZUKI, T., KUSUMOTO, N., MORITA, S. AND ODOMI, M.: Pharmacokinetics of grepafloxacin (IV): Metabolism after oral administration of grepafloxacin in rats, monkeys and humans. Chemotherapy 43(S-1): 131-149, 1995a.
    • (1995) Chemotherapy , vol.43 , Issue.S-1 , pp. 131-149
    • Akiyama, H.1    Koike, M.2    Kyuushiki, K.3    Suzuki, T.4    Kusumoto, N.5    Morita, S.6    Odomi, M.7
  • 4
    • 0028046387 scopus 로고
    • +-bile acid cotransporter using peptide and fusion protein antibodies
    • Gastrointest. Liver Physiol. 30
    • +-bile acid cotransporter using peptide and fusion protein antibodies. Am. J. Physiol. 267(Gastrointest. Liver Physiol. 30): G637-G643, 1994.
    • (1994) Am. J. Physiol. , vol.267
    • Ananthanarayanan, M.1    Cheng, O.I.2    Boyer, J.L.3    Suchy, F.J.4
  • 5
    • 0018237326 scopus 로고
    • Effect of Na on bile acid uptake by isolated rat hepatocytes
    • ANWER, M. S. AND HEGNER, D.: Effect of Na on bile acid uptake by isolated rat hepatocytes. Hoppe-Seyler Z. Physiol. Chem. 359: 181-192, 1978.
    • (1978) Hoppe-Seyler Z. Physiol. Chem. , vol.359 , pp. 181-192
    • Anwer, M.S.1    Hegner, D.2
  • 6
    • 0030098277 scopus 로고    scopus 로고
    • Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver
    • BOSSUYT, X., MULLER, M., HAGENBUCH, G. AND MEIER, P. J.: Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver. J. Pharmacol. Exp. Ther. 276: 891-896, 1996.
    • (1996) J. Pharmacol. Exp. Ther. , vol.276 , pp. 891-896
    • Bossuyt, X.1    Muller, M.2    Hagenbuch, G.3    Meier, P.J.4
  • 8
    • 0019462380 scopus 로고
    • Transport of dibromosulphthalein by isolated rat hepatocytes
    • BLOM, A., KEULEMANS, K. AND MEIJER, D. K. F.: Transport of dibromosulphthalein by isolated rat hepatocytes. Biochem. Pharmacol. 30: 1809-1816, 1981.
    • (1981) Biochem. Pharmacol. , vol.30 , pp. 1809-1816
    • Blom, A.1    Keulemans, K.2    Meijer, D.K.F.3
  • 9
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • BRADFORD, M. M.: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254, 1976.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 10
    • 0015635144 scopus 로고
    • Transport and binding of methotrexate in vivo
    • DEDRICK, R. L., ZAHARKO, D. S. AND LUTZ, R. J.: Transport and binding of methotrexate in vivo. J. Pharm. Sci. 62: 882-890, 1973.
    • (1973) J. Pharm. Sci. , vol.62 , pp. 882-890
    • Dedrick, R.L.1    Zaharko, D.S.2    Lutz, R.J.3
  • 11
    • 0027411562 scopus 로고
    • Active secretion of the fluoroquinolone ciprofloxacin by human intestinal Caco-2 cell layers
    • GRIFFITHS, N. M., HIRST, B. H. AND SIMMONS, N. L.: Active secretion of the fluoroquinolone ciprofloxacin by human intestinal Caco-2 cell layers. J. Pharmacol. 108: 575-576, 1993.
    • (1993) J. Pharmacol. , vol.108 , pp. 575-576
    • Griffiths, N.M.1    Hirst, B.H.2    Simmons, N.L.3
  • 12
    • 0028321687 scopus 로고
    • Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and pefloxacin
    • GRIFFITHS, N. M., HIRST, B. H. AND SIMMONS, N. L.: Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and pefloxacin. J. Pharmacol. Exp. Ther. 269: 496-502, 1994.
    • (1994) J. Pharmacol. Exp. Ther. , vol.269 , pp. 496-502
    • Griffiths, N.M.1    Hirst, B.H.2    Simmons, N.L.3
  • 13
    • 0029990308 scopus 로고    scopus 로고
    • Drug traffic in the hepatobiliary system
    • GROOTHUIS, G. M. M. AND MEIJER, D. K. F.: Drug traffic in the hepatobiliary system. J. Hepatol. 24: 3-28, 1996.
    • (1996) J. Hepatol. , vol.24 , pp. 3-28
    • Groothuis, G.M.M.1    Meijer, D.K.F.2
  • 14
    • 0028063302 scopus 로고
    • Drug excretion mediated by a new prototype of polyspecific transporter
    • GRUNDEMANN, D., GORBOULEV, V., GAMBARYAN, S., VEYHL, M. AND KOEPSELL, H.: Drug excretion mediated by a new prototype of polyspecific transporter. Nature 372: 549-552, 1994.
    • (1994) Nature , vol.372 , pp. 549-552
    • Grundemann, D.1    Gorboulev, V.2    Gambaryan, S.3    Veyhl, M.4    Koepsell, H.5
  • 18
    • 0028147853 scopus 로고
    • The stimulative effect of diffusion potential on enoxacin uptake across rat intestinal brush-border membranes
    • HIRANO, T., ISEKI, K., MIYAZAKI, S., KOBAYASHI, M., SUGAWARA, M. AND MIYAZAKI, K.: The stimulative effect of diffusion potential on enoxacin uptake across rat intestinal brush-border membranes. J. Pharm. Pharmacol. 46: 676-679, 1994.
    • (1994) J. Pharm. Pharmacol. , vol.46 , pp. 676-679
    • Hirano, T.1    Iseki, K.2    Miyazaki, S.3    Kobayashi, M.4    Sugawara, M.5    Miyazaki, K.6
  • 19
    • 0020059805 scopus 로고
    • Hepatic extraction of bile acids in rats
    • IGA, T. AND KLAASSEN, C. D.: Hepatic extraction of bile acids in rats. Biochem. Pharmacol. 31: 205-209, 1982.
    • (1982) Biochem. Pharmacol. , vol.31 , pp. 205-209
    • Iga, T.1    Klaassen, C.D.2
  • 20
    • 0020464777 scopus 로고
    • Taurocholate transport by rat liver sinusoidal membrane vesicle: Evidence of sodium co-transport
    • INOUE, M., KINNE, R., TRANT, T. AND ARIAS, I. M.: Taurocholate transport by rat liver sinusoidal membrane vesicle: Evidence of sodium co-transport. Hepatology 2: 572-579, 1982.
    • (1982) Hepatology , vol.2 , pp. 572-579
    • Inoue, M.1    Kinne, R.2    Trant, T.3    Arias, I.M.4
  • 22
    • 0029950964 scopus 로고    scopus 로고
    • Prediction of in vivo drug disposition from in vitro data based on physiological pharmacokinetics
    • IWATSUBO, T., HIROTA, N., OOIE, T., SUZUKI, H. AND SUGIYAMA: Prediction of in vivo drug disposition from in vitro data based on physiological pharmacokinetics. Biopharm. Drug Dispos. 17: 273-310, 1996.
    • (1996) Biopharm. Drug Dispos. , vol.17 , pp. 273-310
    • Iwatsubo, T.1    Hirota, N.2    Ooie, T.3    Suzuki, H.4    Sugiyama5
  • 23
    • 0026331027 scopus 로고
    • Expression of the hepatocellular chloride-dependent sulfobromophthalein uptake system in Xenopus laevis oocytes
    • JACQUEMIN, E., HAGENBUCH, B., STIEGER, B., WOLKOFF, A. W. AND MEIER, P. J.: Expression of the hepatocellular chloride-dependent sulfobromophthalein uptake system in Xenopus laevis oocytes. J. Clin. Inverst. 88: 2146-2149, 1991.
    • (1991) J. Clin. Inverst. , vol.88 , pp. 2146-2149
    • Jacquemin, E.1    Hagenbuch, B.2    Stieger, B.3    Wolkoff, A.W.4    Meier, P.J.5
  • 25
    • 0023707091 scopus 로고
    • Kinetic analysis of in vivo receptor-dependent binding of human epidermal growth factor by rat tissues
    • KIM, D. C., SUGIYAMA, Y., SATOH, H., FUWA, T., IGA, T. AND HANANO, M.: Kinetic analysis of in vivo receptor-dependent binding of human epidermal growth factor by rat tissues. J. Pharm. Sci. 77: 200-207, 1988.
    • (1988) J. Pharm. Sci. , vol.77 , pp. 200-207
    • Kim, D.C.1    Sugiyama, Y.2    Satoh, H.3    Fuwa, T.4    Iga, T.5    Hanano, M.6
  • 27
    • 0018962319 scopus 로고
    • Kinetic studies on the deethylation of ethoxybenzamide: A comparative study with isolated hepatocytes and liver microsomes of rat
    • LIN, J. H., SUGIYAMA, Y., AWAZU, S. AND HANANO, M.: Kinetic studies on the deethylation of ethoxybenzamide: A comparative study with isolated hepatocytes and liver microsomes of rat. Biochem. Pharmacol. 29: 2825-2830, 1980.
    • (1980) Biochem. Pharmacol. , vol.29 , pp. 2825-2830
    • Lin, J.H.1    Sugiyama, Y.2    Awazu, S.3    Hanano, M.4
  • 30
    • 0029615982 scopus 로고
    • Molecular mechanism of hepatic bile salt transport from sinusoidal blood into bile
    • Gastrointest. Liver Physiol. 32
    • MEIER, P. J.: Molecular mechanism of hepatic bile salt transport from sinusoidal blood into bile. Am. Physiol. Soc. 269(Gastrointest. Liver Physiol. 32): G801-G812, 1995.
    • (1995) Am. Physiol. Soc. , vol.269
    • Meier, P.J.1
  • 31
    • 0025281139 scopus 로고
    • Carrier-mediated transport in the hepatic distribution and elimination of drug with special reference to the category of organic anions
    • MEIJER, D. K. F., MOL, W. E. M., MULLER, M. AND KURZ, G.: Carrier-mediated transport in the hepatic distribution and elimination of drug with special reference to the category of organic anions. J. Pharmacokin. Biopharm. 18: 35-70, 1990.
    • (1990) J. Pharmacokin. Biopharm. , vol.18 , pp. 35-70
    • Meijer, D.K.F.1    Mol, W.E.M.2    Muller, M.3    Kurz, G.4
  • 32
    • 0023184551 scopus 로고
    • Kinetics of hepatic transport of 4-methylumbelliferone in rats: Analysis by multiple indicator dilution method
    • MIYAUCHI, S., SUGIYAMA, Y., SAWADA, Y., MORITA, K., IGA, T. AND HANANO, M.: Kinetics of hepatic transport of 4-methylumbelliferone in rats: Analysis by multiple indicator dilution method. J. Pharmacokin. Biopharm. 15: 25-38, 1987.
    • (1987) J. Pharmacokin. Biopharm. , vol.15 , pp. 25-38
    • Miyauchi, S.1    Sugiyama, Y.2    Sawada, Y.3    Morita, K.4    Iga, T.5    Hanano, M.6
  • 33
    • 0023903025 scopus 로고
    • Mechanisms for the hepatic uptake of organic cations: Studies with the muscle relaxant vecuronium in isolated rat hepatocytes
    • MOL, W. E. M., FOKKEMA, G. N., WEERT, B. AND MEIJER, D. K. F.: Mechanisms for the hepatic uptake of organic cations: Studies with the muscle relaxant vecuronium in isolated rat hepatocytes. J. Pharmacol. Exp. Ther. 244: 268-275, 1988.
    • (1988) J. Pharmacol. Exp. Ther. , vol.244 , pp. 268-275
    • Mol, W.E.M.1    Fokkema, G.N.2    Weert, B.3    Meijer, D.K.F.4
  • 34
    • 0025938154 scopus 로고
    • Mechanisms for the uptake of cationic drugs by the liver: A study with tributylmethylammonium (TBuMA)
    • MOL, W. E. M., FOKKEMA, G. N., WEERT, B. AND MEIJER, D. K. F.: Mechanisms for the uptake of cationic drugs by the liver: A study with tributylmethylammonium (TBuMA). J. Pharmacol. Exp. Ther. 258: 537-543, 1991.
    • (1991) J. Pharmacol. Exp. Ther. , vol.258 , pp. 537-543
    • Mol, W.E.M.1    Fokkema, G.N.2    Weert, B.3    Meijer, D.K.F.4
  • 35
    • 0026627893 scopus 로고
    • Investigations on the hepatic uptake systems for organic cations with a photoaffinity probe of procainamide
    • MOL, W. E. M., MULLER, M., KURZ, G. AND MEIJER, D. K. F.: Investigations on the hepatic uptake systems for organic cations with a photoaffinity probe of procainamide. Biochem. Pharmacol. 43: 2217-2226, 1992.
    • (1992) Biochem. Pharmacol. , vol.43 , pp. 2217-2226
    • Mol, W.E.M.1    Muller, M.2    Kurz, G.3    Meijer, D.K.F.4
  • 36
    • 0025681666 scopus 로고
    • 1-methylnicotinamide by organic cation-proton exchange in rat liver membrane vesicles
    • Gastrointest. Liver Physiol. 22
    • 1-methylnicotinamide by organic cation-proton exchange in rat liver membrane vesicles. Am. J. Physiol. 259(Gastrointest. Liver Physiol. 22): G973-G982, 1990.
    • (1990) Am. J. Physiol. , vol.259
    • Moseley, R.H.1    Morrissette, J.2    Johnson, T.R.3
  • 37
    • 15444359936 scopus 로고
    • Hepatic transport systems for bulky organic cations: Kinetic and photoaffkinity labeling studies to characterize potential carrier proteins for uptake of amphipathic (type 2) cation
    • MULLER, M., MOL, W. E. M., KURZ, G. AND MEIJER, D. K. F.: Hepatic transport systems for bulky organic cations: Kinetic and photoaffkinity labeling studies to characterize potential carrier proteins for uptake of amphipathic (type 2) cation. Hepatology 8: 1401, 1988.
    • (1988) Hepatology , vol.8 , pp. 1401
    • Muller, M.1    Mol, W.E.M.2    Kurz, G.3    Meijer, D.K.F.4
  • 38
    • 0028283927 scopus 로고
    • 2 receptor antagonist, cimetidine and nizatidine into isolated rat hepatocytes: Contribution of type I system
    • 2 receptor antagonist, cimetidine and nizatidine into isolated rat hepatocytes: Contribution of type I system. J. Pharmacol. Exp. Ther. 269: 1220-1227, 1994.
    • (1994) J. Pharmacol. Exp. Ther. , vol.269 , pp. 1220-1227
    • Nakamura, H.1    Sano, H.2    Yamazaki, M.3    Sugiyama, Y.4
  • 39
    • 0025672578 scopus 로고
    • Interaction of ofloxacin with organic cation transport system in rat renal brush-border membranes
    • OKANO, T., MAEGAWA, H., INUI, K. AND HORI, R.: Interaction of ofloxacin with organic cation transport system in rat renal brush-border membranes. J. Pharmacol. Exp. Ther. 255: 1033-1037, 1990.
    • (1990) J. Pharmacol. Exp. Ther. , vol.255 , pp. 1033-1037
    • Okano, T.1    Maegawa, H.2    Inui, K.3    Hori, R.4
  • 40
    • 0024273132 scopus 로고
    • Structure-tissue distribution relationship based on physiological pharmacokinetics for NY-198, new antimicrobial agent, and the related pyridone carboxylic acids
    • OKEZAKI, E., TERASAKI, T., MAKAMURA, M., NAGATA, O., KATO, H. AND TSUJI, A.: Structure-tissue distribution relationship based on physiological pharmacokinetics for NY-198, new antimicrobial agent, and the related pyridone carboxylic acids. Drug. Metab. Dispos. 16: 865-874, 1988.
    • (1988) Drug. Metab. Dispos. , vol.16 , pp. 865-874
    • Okezaki, E.1    Terasaki, T.2    Makamura, M.3    Nagata, O.4    Kato, H.5    Tsuji, A.6
  • 41
    • 0023933136 scopus 로고
    • Effects of basic drugs on the hepatic transport of cardiac glycosides in rats
    • OKUDAIRA, K., SAWADA, Y., SUGIYAMA, Y., IGA, T. AND HANANO, M.: Effects of basic drugs on the hepatic transport of cardiac glycosides in rats. Biochem. Pharmacol. 37: 2949-2955, 1988.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 2949-2955
    • Okudaira, K.1    Sawada, Y.2    Sugiyama, Y.3    Iga, T.4    Hanano, M.5
  • 42
    • 0022609024 scopus 로고
    • Correlation between in vitro microsomal enzymes activity and whole organ hepatic elimination kinetics: Analysis with a dispersion model
    • ROBERTS, M. AND ROWLAND, M.: Correlation between in vitro microsomal enzymes activity and whole organ hepatic elimination kinetics: Analysis with a dispersion model. J. Pharm. Pharmacol. 38: 177-181, 1986.
    • (1986) J. Pharm. Pharmacol. , vol.38 , pp. 177-181
    • Roberts, M.1    Rowland, M.2
  • 43
    • 0018901053 scopus 로고
    • Transport systems of isolated hepatocytes: Studies on the transport of biliary compounds
    • SCHWENK, M.: Transport systems of isolated hepatocytes: Studies on the transport of biliary compounds. Arch. Toxicol. 44: 113-126, 1980.
    • (1980) Arch. Toxicol. , vol.44 , pp. 113-126
    • Schwenk, M.1
  • 44
    • 84880505647 scopus 로고
    • Physiologically based pharmacokinetics of drug-drug interaction: A study of tolbutamide-sulfonamide interaction in rats
    • SUGITA, O., SAWADA, Y., SUGIYAMA, Y., IGA, T. AND HANANO, M.: Physiologically based pharmacokinetics of drug-drug interaction: A study of tolbutamide-sulfonamide interaction in rats. J. Pharmacokin. Biopharm. 10: 297-316, 1982.
    • (1982) J. Pharmacokin. Biopharm. , vol.10 , pp. 297-316
    • Sugita, O.1    Sawada, Y.2    Sugiyama, Y.3    Iga, T.4    Hanano, M.5
  • 45
    • 0020546649 scopus 로고
    • Characteristics of the uptake of cysteine-containing leukotrienes by isolated hepatocytes
    • UEHARA, N., ORMSTAD, K., ORNING, L., HAMMARSLOM, S.: Characteristics of the uptake of cysteine-containing leukotrienes by isolated hepatocytes. Biochim. Biophys. Acta 762: 69-74, 1983.
    • (1983) Biochim. Biophys. Acta , vol.762 , pp. 69-74
    • Uehara, N.1    Ormstad, K.2    Orning, L.3    Hammarslom, S.4
  • 46
    • 0027373329 scopus 로고
    • Bisubstrates that interact with both, renal contraluminal organic anion and organic cation transport systems
    • ULLRICH, K. J., RUMRICH, G., DAVID, C. AND FRITZSCH, G.: Bisubstrates that interact with both, renal contraluminal organic anion and organic cation transport systems. E. J. Physiol. 425: 300-312, 1993.
    • (1993) E. J. Physiol. , vol.425 , pp. 300-312
    • Ullrich, K.J.1    Rumrich, G.2    David, C.3    Fritzsch, G.4
  • 47
    • 0019854279 scopus 로고
    • A pharmacokinetic analysis program (MULTI) for microcomputer
    • YAMAOKA, K., TANIGAWARA, Y., NAKAGAMI, Y. AND UNO, T.: A pharmacokinetic analysis program (MULTI) for microcomputer. J. Pharmacobio-Dyn. 4: 879-885, 1981.
    • (1981) J. Pharmacobio-Dyn. , vol.4 , pp. 879-885
    • Yamaoka, K.1    Tanigawara, Y.2    Nakagami, Y.3    Uno, T.4
  • 48
    • 0026501527 scopus 로고
    • Utilization of ATP-depleted cells in the analysis of taurocholate uptake by isolated rat hepatocytes
    • YAMAZAKI, M., SUGIYAMA, Y., SUZUKI, H., IGA, T. AND HANANO, M.: Utilization of ATP-depleted cells in the analysis of taurocholate uptake by isolated rat hepatocytes. J. Hepatol. 14: 54-63, 1992a.
    • (1992) J. Hepatol. , vol.14 , pp. 54-63
    • Yamazaki, M.1    Sugiyama, Y.2    Suzuki, H.3    Iga, T.4    Hanano, M.5
  • 49
    • 0026536932 scopus 로고
    • Uptake of organic anions by isolated rat hepatocytes: A classification in terms of ATP-dependency
    • YAMAZAKI, M., SUZUKI, H., SUGIYAMA, Y., IGA, T. AND HANANO, M.; Uptake of organic anions by isolated rat hepatocytes: A classification in terms of ATP-dependency. J. Hepatol. 14: 41-47, 1992b.
    • (1992) J. Hepatol. , vol.14 , pp. 41-47
    • Yamazaki, M.1    Suzuki, H.2    Sugiyama, Y.3    Iga, T.4    Hanano, M.5
  • 50
    • 0027238368 scopus 로고
    • Different relationships between cellular ATP and hepatic uptake among taurocholate, cholate and organic anions
    • Gastrointest. Liver Physiol. 27
    • YAMAZAKI, M., SUZUKI, H., HANANO, M. AND SUGIYAMA, Y.: Different relationships between cellular ATP and hepatic uptake among taurocholate, cholate and organic anions. Am. J. Physiol. 264(Gastrointest. Liver Physiol. 27): G693-G701, 1993a.
    • (1993) Am. J. Physiol. , vol.264
    • Yamazaki, M.1    Suzuki, H.2    Hanano, M.3    Sugiyama, Y.4
  • 51
    • 0027392882 scopus 로고
    • +-independent multispecific transporter mediated active transport of pravastatin into rat liver
    • Gastrointest. Liver Physiol. 27
    • +-independent multispecific transporter mediated active transport of pravastatin into rat liver. Am. J. Physiol. 264(Gastrointest. Liver Physiol. 27): G36-G44, 1993b.
    • (1993) Am. J. Physiol. , vol.264
    • Yamazaki, M.1    Suzuki, H.2    Hanano, M.3    Tokui, T.4    Komai, T.5    Sugiyama, Y.6
  • 52
    • 0029926676 scopus 로고    scopus 로고
    • Recent advances in carrier-mediated hepatic uptake and biliary excretion of xenobiotics
    • YAMAZAKI, M., SUZUKI, H., SUGIYAMA, Y.: Recent advances in carrier-mediated hepatic uptake and biliary excretion of xenobiotics. Pharm. Res. 13: 497-513, 1996.
    • (1996) Pharm. Res. , vol.13 , pp. 497-513
    • Yamazaki, M.1    Suzuki, H.2    Sugiyama, Y.3
  • 53
    • 0025361244 scopus 로고
    • Kinetic analysis of the downregulation of epidermal growth factor receptors in rats in vivo
    • Cell Physiol. 21
    • YANAI, M., SUGIYAMA, Y., IGA, T., FUWA, T. AND HANANO, M.: Kinetic analysis of the downregulation of epidermal growth factor receptors in rats in vivo. Am. J. Physiol. 258(Cell Physiol. 21): C593-C598, 1990.
    • (1990) Am. J. Physiol. , vol.258
    • Yanai, M.1    Sugiyama, Y.2    Iga, T.3    Fuwa, T.4    Hanano, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.