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Volumn 46, Issue 1, 2003, Pages 136-137

An E23K single nucleotide polymorphism in the islet ATP-sensitive potassium channel gene (Kir6.2) contributes as much to the risk of Type II diabetes in Caucasians as the PPARγ Pro12Ala variant (3)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; POTASSIUM; POTASSIUM CHANNEL;

EID: 0037280761     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-002-0947-x     Document Type: Letter
Times cited : (72)

References (7)
  • 1
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    • The common PPARg proll2ala polymorphism is associated with decreased risk of type 2 diabetes
    • Altshuler D, Hirschhorn J, Klannemark M et al. (2000) The common PPARg proll2ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 26: 76-80
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    • Altshuler, D.1    Hirschhorn, J.2    Klannemark, M.3
  • 2
    • 0034745185 scopus 로고    scopus 로고
    • The Prol2 →Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: Possible involvement in impairment of insulin secretion in individuals with type 2 diabetes
    • Mori H, Ikegami H, Kawaguchi Y et al. (2001) The Prol2 →Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin secretion in individuals with type 2 diabetes. Diabetes 50:891-894
    • (2001) Diabetes , vol.50 , pp. 891-894
    • Mori, H.1    Ikegami, H.2    Kawaguchi, Y.3
  • 3
    • 0034677634 scopus 로고    scopus 로고
    • Targeted overactivity of beta cell K(ATP) channels induces profound neonatal diabetes
    • Koster JC, Marshall BA, Ensor N, Corbett JA, Nichols CG (2000) Targeted overactivity of beta cell K(ATP) channels induces profound neonatal diabetes. Cell 100:645-654
    • (2000) Cell , vol.100 , pp. 645-654
    • Koster, J.C.1    Marshall, B.A.2    Ensor, N.3    Corbett, J.A.4    Nichols, C.G.5
  • 4
    • 0031773333 scopus 로고    scopus 로고
    • Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): A meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians
    • Hani EH, Boutin P, Durand E et al. (1998) Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): a meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians. Diabetologia 41: 1511-1515
    • (1998) Diabetologia , vol.41 , pp. 1511-1515
    • Hani, E.H.1    Boutin, P.2    Durand, E.3
  • 5
    • 0036314298 scopus 로고    scopus 로고
    • K(IR)6.2 polymorphism predisposes to type 2 diabetes by inducing overactivity of pancreatic beta-cell ATP-sensitive K(+) channels
    • Schwanstecher C, Meyer U, Schwanstecher M (2002) K(IR)6.2 polymorphism predisposes to type 2 diabetes by inducing overactivity of pancreatic beta-cell ATP-sensitive K(+) channels. Diabetes 51:875-879
    • (2002) Diabetes , vol.51 , pp. 875-879
    • Schwanstecher, C.1    Meyer, U.2    Schwanstecher, M.3
  • 6
    • 0035043009 scopus 로고    scopus 로고
    • Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53)
    • Gloyn AL, Hashim Y, Ashcroft SJ, Ashfield R, Wiltshire S, Turner RC (2001) Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53). Diabet Med 18:206-212
    • (2001) Diabet Med , vol.18 , pp. 206-212
    • Gloyn, A.L.1    Hashim, Y.2    Ashcroft, S.J.3    Ashfield, R.4    Wiltshire, S.5    Turner, R.C.6
  • 7
    • 0023083290 scopus 로고
    • On the epidemiology of oral contraceptives and disease
    • Prentice RL, Thomas DB (1987) On the epidemiology of oral contraceptives and disease. Adv Cancer Res 49: 285401
    • (1987) Adv Cancer Res , vol.49 , pp. 285401
    • Prentice, R.L.1    Thomas, D.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.