Carbonic anhydrase activators: Activation of the human tumor-associated isozymes IX and XII with amino acids and amines

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 7, 2008, Pages 3530-3536

  Pastorekova, Silvia ^a   Vullo, Daniela ^b   Nishimori, Isao ^c   Scozzafava, Andrea ^b   Pastorek, Jaromir ^a   Supuran, Claudiu T ^b  

^a INSTITUTE OF VIROLOGY   (Slovakia)

^b UNIVERSITY OF FLORENCE   (Italy)

^c KOCHI MEDICAL SCHOOL   (Japan)

Author keywords

Amine; Amino acid; Carbonic anhydrase; Enzyme activator; Hypoxia; Isoforms IX and XII; Tumor

Indexed keywords

ADRENALIN; AMINE; AMINO ACID; CARBONATE DEHYDRATASE IX; CARBONATE DEHYDRATASE XII; ISOENZYME; MORPHOLINE DERIVATIVE; PROTON; SEROTONIN; ZINC DERIVATIVE;

ARTICLE; CATALYSIS; COMPLEX FORMATION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; HUMAN; PROTON TRANSPORT; TUMOR GROWTH;

AMINES; AMINO ACIDS; ANTIGENS, NEOPLASM; CARBONIC ANHYDRASES; CONSERVED SEQUENCE; ENZYME ACTIVATION; HUMANS; ISOENZYMES; KINETICS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NEOPLASMS; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 41649092883     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.02.021     Document Type: Article

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