Carbonic anhydrase activators: The first activation study of the human secretory isoform VI with amino acids and amines

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 15, 2007, Pages 5351-5357

  Nishimori, Isao ^a   Onishi, Saburo ^a   Vullo, Daniela ^b   Innocenti, Alessio ^b   Scozzafava, Andrea ^b   Supuran, Claudiu T ^b  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Amine; Amino acid; Carbonic anhydrase; Isoform VI; Kinetics; Proton transfer; Stopped flow

Indexed keywords

ALIPHATIC AMINE; AMINE; AMINO ACID DERIVATIVE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE ACTIVATOR; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE VI; DOPA; ENZYME ACTIVATOR; HISTAMINE; HISTIDINE; PHENYLALANINE; PYRIDINE DERIVATIVE; SEROTONIN; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DRUG STRUCTURE; ENZYME ACTIVE SITE; HYDRATION; KINETICS; PH; PROTON TRANSPORT;

AMINES; AMINO ACID SEQUENCE; AMINO ACIDS; CARBONIC ANHYDRASES; CLONING, MOLECULAR; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN ISOFORMS; PROTEIN SUBUNITS;

BACTERIA (MICROORGANISMS);

EID: 34249946261     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.03.004     Document Type: Article

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