Carbonic anhydrase activators: An activation study of the human mitochondrial isoforms VA and VB with amino acids and amines

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 5, 2007, Pages 1336-1340

  Vullo, Daniela ^a   Nishimori, Isao ^b   Innocenti, Alessio ^a   Scozzafava, Andrea ^a   Supuran, Claudiu T ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b KOCHI MEDICAL SCHOOL   (Japan)

Author keywords

Activation; Amine; Amino acid; Carbonic anhydrase; Histamine; Isoform VA; Mitochondria; VB

Indexed keywords

2 (2 PYRIDYL)ETHYLAMINE; 4 (2 AMINOETHYL)MORPHOLINE; AMINE; AMINO ACID; CARBONATE DEHYDRATASE; DOPA; DOPAMINE; HISTAMINE; ISOENZYME; LEVODOPA; MORPHOLINE DERIVATIVE; PYRIDINE; SEROTONIN; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CYTOSOL; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVE SITE; HUMAN; MITOCHONDRION; PROTON TRANSPORT; REACTION ANALYSIS; STRUCTURE ANALYSIS;

AMINES; AMINO ACIDS; CARBONIC ANHYDRASES; CATALYSIS; ENZYME ACTIVATION; HUMANS; KINETICS; MITOCHONDRIAL PROTEINS; PROTEIN ISOFORMS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33846962166     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.11.075     Document Type: Article

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