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Volumn 17, Issue 15, 2007, Pages 4107-4112

Carbonic anhydrase activators: Activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines

Author keywords

Activator; Alzheimer's disease; Amine; Amino acid; Carbonic anhydrase; Proton transfer

Indexed keywords

AROMATIC AMINE; CARBONATE ANHYDRASE VII; CARBONATE ANHYDRASE XIV; CARBONATE DEHYDRATASE; DOPAMINE; HETEROCYCLIC AMINE; HISTIDINE; SEROTONIN; UNCLASSIFIED DRUG;

EID: 34347402594     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.05.052     Document Type: Article
Times cited : (49)

References (43)
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    • Activation of carbonic anhydrase isozymes
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    • (2000) The Carbonic Anhydrases - New Horizons , pp. 197
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    • Supuran C.T., Scozzafava A., and Conway J. (Eds), CRC Press, Boca Raton, New York, London
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    • Supuran C.T. Carbonic anhydrases: catalytic and inhibition mechanisms, distribution and physiological roles. In: Supuran C.T., Scozzafava A., and Conway J. (Eds). Carbonic anhydrase - Its inhibitors and activators (2004), CRC Press, Boca Raton 1
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    • Development of sulfonamide carbonic anhydrase inhibitors
    • Supuran C.T., Scozzafava A., and Conway J. (Eds), CRC Press, Boca Raton
    • Supuran C.T., Scozzafava A., and Casini A. Development of sulfonamide carbonic anhydrase inhibitors. In: Supuran C.T., Scozzafava A., and Conway J. (Eds). Carbonic anhydrase - Its inhibitors and activators (2004), CRC Press, Boca Raton 67
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    • Nishimori, I.; Vullo, D.; Innocenti, A.; Scozzafava, A.; Supuran, C.T. Bioorg. Med. Chem. 2007, 15, in press. doi:10.1016/j.bmc.2007.03.004.
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    • 2 concentrations ranged from 1.7 to 17 mM for the determination of the kinetic parameters and activation constants. For each activator at least six traces of the initial 5-10% of the reaction have been used for determining the initial velocity. The uncatalyzed rates were determined in the same manner and subtracted from the total observed rates. Stock solutions of activators 1-18 (10 mM) were prepared in distilled-deionized water and dilutions up to 0.001 μM were done thereafter with distilled-deionized water. ...
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.