메뉴 건너뛰기




Volumn 41, Issue 3, 2008, Pages 183-194

Osteoclasts - The innate immune cells of the bone

Author keywords

Bone; Differentiation; Innate immune receptors; Osteoclast; RANKL; Signal transduction

Indexed keywords

COLONY STIMULATING FACTOR 1; FC RECEPTOR; FC RECEPTOR GAMMA; IMMUNOGLOBULIN RECEPTOR; IMMUNORECEPTOR TYROSINE BASED ACTIVATION MOTIF RECEPTOR; KILLER CELL ACTIVATING RECEPTOR ASSOCIATED PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; UNCLASSIFIED DRUG;

EID: 41449099766     PISSN: 08916934     EISSN: 1607842X     Source Type: Journal    
DOI: 10.1080/08916930701693180     Document Type: Article
Times cited : (51)

References (119)
  • 3
    • 0017851297 scopus 로고
    • Rapid activation of the medullary bone osteoclast cell surface by parathyroid hormone
    • Miller, SC (1978) Rapid activation of the medullary bone osteoclast cell surface by parathyroid hormone. J Cell Biol, 76:3, pp. 615-618.
    • (1978) J Cell Biol , vol.76 , Issue.3 , pp. 615-618
    • Miller, S.C.1
  • 4
    • 33947497852 scopus 로고    scopus 로고
    • Osteoclasts: What do they do and how do they do it?
    • Teitelbaum, SL (2007) Osteoclasts: What do they do and how do they do it?. Am J Pathol, 170:2, pp. 427-435.
    • (2007) Am J Pathol , vol.170 , Issue.2 , pp. 427-435
    • Teitelbaum, S.L.1
  • 5
    • 34247889894 scopus 로고    scopus 로고
    • The multiple roles of osteoclasts in host defense: Bone remodeling and hematopoietic stem cell mobilization
    • Kollet, O., Dar, A. and Lapidot, T. (2007) The multiple roles of osteoclasts in host defense: Bone remodeling and hematopoietic stem cell mobilization. Annu Rev Immunol, 25, pp. 51-69.
    • (2007) Annu Rev Immunol , vol.25 , pp. 51-69
    • Kollet, O.1    Dar, A.2    Lapidot, T.3
  • 8
    • 0346216133 scopus 로고    scopus 로고
    • Human osteoclasts express different CXC chemokines depending on cell culture substrate: Molecular and immunocytochemical evidence of high levels of CXCL10 and CXCL12
    • Grassi, F., Piacentini, A., Cristino, S., Toneguzzi, S., Cavallo, C., Facchini, A. and Lisignoli, G. (2003) Human osteoclasts express different CXC chemokines depending on cell culture substrate: Molecular and immunocytochemical evidence of high levels of CXCL10 and CXCL12. Histochem Cell Biol, 120:5, pp. 391-400.
    • (2003) Histochem Cell Biol , vol.120 , Issue.5 , pp. 391-400
    • Grassi, F.1    Piacentini, A.2    Cristino, S.3    Toneguzzi, S.4    Cavallo, C.5    Facchini, A.6    Lisignoli, G.7
  • 9
    • 0042838281 scopus 로고    scopus 로고
    • Inflammatory mediators as essential elements in bone remodeling
    • Goldring, SR (2003) Inflammatory mediators as essential elements in bone remodeling. Calcif Tissue Int, 73:2, pp. 97-100.
    • (2003) Calcif Tissue Int , vol.73 , Issue.2 , pp. 97-100
    • Goldring, S.R.1
  • 10
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle, WJ, Simonet, WS and Lacey, DL (2003) Osteoclast differentiation and activation. Nature, 423:6937, pp. 337-342.
    • (2003) Nature , vol.423 , Issue.6937 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 11
    • 0043267732 scopus 로고    scopus 로고
    • Genetic regulation of osteoclast development and function
    • Teitelbaum, SL and Ross, FP (2003) Genetic regulation of osteoclast development and function. Nat Rev Genet, 4:8, pp. 638-649.
    • (2003) Nat Rev Genet , vol.4 , Issue.8 , pp. 638-649
    • Teitelbaum, S.L.1    Ross, F.P.2
  • 13
    • 0016811449 scopus 로고
    • Bone resorption restored in osteopetrotic mice by transplants of normal bone marrow and spleen cells
    • Walker, DG (1975) Bone resorption restored in osteopetrotic mice by transplants of normal bone marrow and spleen cells. Science, 190:4216, pp. 784-785.
    • (1975) Science , vol.190 , Issue.4216 , pp. 784-785
    • Walker, D.G.1
  • 17
    • 0000371126 scopus 로고    scopus 로고
    • TRANCE is a TNF family member that regulates dendritic cell and osteoclast function
    • Wong, BR, Josien, R. and Choi, Y. (1999) TRANCE is a TNF family member that regulates dendritic cell and osteoclast function. J Leukoc Biol, 65:6, pp. 715-724.
    • (1999) J Leukoc Biol , vol.65 , Issue.6 , pp. 715-724
    • Wong, B.R.1    Josien, R.2    Choi, Y.3
  • 18
    • 0033532191 scopus 로고    scopus 로고
    • Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival
    • Lum, L., Wong, BR, Josien, R., Becherer, JD, Erdjument-Bromage, H., Schlondorff, J., Tempst, P., Choi, Y. and Blobel, CP (1999) Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival. J Biol Chem, 274:19, pp. 13613-13618.
    • (1999) J Biol Chem , vol.274 , Issue.19 , pp. 13613-13618
    • Lum, L.1    Wong, B.R.2    Josien, R.3    Becherer, J.D.4    Erdjument-Bromage, H.5    Schlondorff, J.6    Tempst, P.7    Choi, Y.8    Blobel, C.P.9
  • 19
    • 0036218666 scopus 로고    scopus 로고
    • RANK-L and RANK: T cells, bone loss, and mammalian evolution
    • Theill, LE, Boyle, WJ and Penninger, JM (2002) RANK-L and RANK: T cells, bone loss, and mammalian evolution. Annu Rev Immunol, 20, pp. 795-823.
    • (2002) Annu Rev Immunol , vol.20 , pp. 795-823
    • Theill, L.E.1    Boyle, W.J.2    Penninger, J.M.3
  • 22
    • 3242781731 scopus 로고    scopus 로고
    • Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases
    • Hofbauer, LC and Schoppet, M. (2004) Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases. J Am Med Assoc, 292:4, pp. 490-495.
    • (2004) J Am Med Assoc , vol.292 , Issue.4 , pp. 490-495
    • Hofbauer, L.C.1    Schoppet, M.2
  • 23
    • 12944262423 scopus 로고    scopus 로고
    • RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism
    • Li, J., Sarosi, I., Yan, XQ, Morony, S., Capparelli, C., Tan, HL, McCabe, S., Elliott, R., Scully, S. and Van, G. (2000) RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. Proc Natl Acad Sci USA, 97:4, pp. 1566-1571.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.4 , pp. 1566-1571
    • Li, J.1    Sarosi, I.2    Yan, X.Q.3    Morony, S.4    Capparelli, C.5    Tan, H.L.6    McCabe, S.7    Elliott, R.8    Scully, S.9    Van, G.10
  • 28
    • 8644246691 scopus 로고    scopus 로고
    • Heritable disorders of the RANKL/OPG/RANK signaling pathway
    • Whyte, MP and Mumm, S. (2004) Heritable disorders of the RANKL/OPG/RANK signaling pathway. J Musculoskelet Neuronal Interact, 4:3, pp. 254-267.
    • (2004) J Musculoskelet Neuronal Interact , vol.4 , Issue.3 , pp. 254-267
    • Whyte, M.P.1    Mumm, S.2
  • 30
    • 18544371504 scopus 로고    scopus 로고
    • A mutation in the gene TNFRSF11B encoding osteoprotegerin causes an idiopathic hyperphosphatasia phenotype
    • Cundy, T., Hegde, M., Naot, D., Chong, B., King, A., Wallace, R., Mulley, J., Love, DR, Seidel, J. and Fawkner, M. (2002) A mutation in the gene TNFRSF11B encoding osteoprotegerin causes an idiopathic hyperphosphatasia phenotype. Hum Mol Genet, 11:18, pp. 2119-2127.
    • (2002) Hum Mol Genet , vol.11 , Issue.18 , pp. 2119-2127
    • Cundy, T.1    Hegde, M.2    Naot, D.3    Chong, B.4    King, A.5    Wallace, R.6    Mulley, J.7    Love, D.R.8    Seidel, J.9    Fawkner, M.10
  • 31
    • 0036736816 scopus 로고    scopus 로고
    • Sequence variations in the osteoprotegerin gene promoter in patients with postmenopausal osteoporosis
    • Arko, B., Prezelj, J., Komel, R., Kocijancic, A., Hudler, P. and Marc, J. (2002) Sequence variations in the osteoprotegerin gene promoter in patients with postmenopausal osteoporosis. J Clin Endocrinol Metab, 87:9, pp. 4080-4084.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.9 , pp. 4080-4084
    • Arko, B.1    Prezelj, J.2    Komel, R.3    Kocijancic, A.4    Hudler, P.5    Marc, J.6
  • 32
    • 0035868884 scopus 로고    scopus 로고
    • Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis
    • Kobayashi, N., Kadono, Y., Naito, A., Matsumoto, K., Yamamoto, T., Tanaka, S. and Inoue, J. (2001) Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis. Embo J, 20:6, pp. 1271-1280.
    • (2001) Embo J , vol.20 , Issue.6 , pp. 1271-1280
    • Kobayashi, N.1    Kadono, Y.2    Naito, A.3    Matsumoto, K.4    Yamamoto, T.5    Tanaka, S.6    Inoue, J.7
  • 34
    • 18744366041 scopus 로고    scopus 로고
    • Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
    • Takayanagi, H., Kim, S., Koga, T., Nishina, H., Isshiki, M., Yoshida, H., Saiura, A., Isobe, M., Yokochi, T. and Inoue, J. (2002) Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev Cell, 3:6, pp. 889-901.
    • (2002) Dev Cell , vol.3 , Issue.6 , pp. 889-901
    • Takayanagi, H.1    Kim, S.2    Koga, T.3    Nishina, H.4    Isshiki, M.5    Yoshida, H.6    Saiura, A.7    Isobe, M.8    Yokochi, T.9    Inoue, J.10
  • 37
    • 0025332897 scopus 로고
    • The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene
    • Yoshida, H., Hayashi, S., Kunisada, T., Ogawa, M., Nishikawa, S., Okamura, H., Sudo, T. and Shultz, LD (1990) The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature, 345:6274, pp. 442-444.
    • (1990) Nature , vol.345 , Issue.6274 , pp. 442-444
    • Yoshida, H.1    Hayashi, S.2    Kunisada, T.3    Ogawa, M.4    Nishikawa, S.5    Okamura, H.6    Sudo, T.7    Shultz, L.D.8
  • 39
    • 0037332596 scopus 로고    scopus 로고
    • c-Fms and the alphavbeta3 integrin collaborate during osteoclast differentiation
    • Faccio, R., Takeshita, S., Zallone, A., Ross, FP and Teitelbaum, SL (2003) c-Fms and the alphavbeta3 integrin collaborate during osteoclast differentiation. J Clin Invest, 111:5, pp. 749-758.
    • (2003) J Clin Invest , vol.111 , Issue.5 , pp. 749-758
    • Faccio, R.1    Takeshita, S.2    Zallone, A.3    Ross, F.P.4    Teitelbaum, S.L.5
  • 41
    • 17644389199 scopus 로고    scopus 로고
    • TNF/TNFR family members in costimulation of T cell responses
    • Watts, TH (2005) TNF/TNFR family members in costimulation of T cell responses. Annu Rev Immunol, 23, pp. 23-68.
    • (2005) Annu Rev Immunol , vol.23 , pp. 23-68
    • Watts, T.H.1
  • 42
    • 28544438330 scopus 로고    scopus 로고
    • Role of ITAM-containing adapter proteins and their receptors in the immune system and bone
    • Humphrey, MB, Lanier, LL and Nakamura, MC (2005) Role of ITAM-containing adapter proteins and their receptors in the immune system and bone. Immunol Rev, 208, pp. 50-65.
    • (2005) Immunol Rev , vol.208 , pp. 50-65
    • Humphrey, M.B.1    Lanier, L.L.2    Nakamura, M.C.3
  • 43
    • 0036221481 scopus 로고    scopus 로고
    • Signal transduction mediated by the T cell antigen receptor: The role of adapter proteins
    • Samelson, LE (2002) Signal transduction mediated by the T cell antigen receptor: The role of adapter proteins. Annu Rev Immunol, 20, pp. 371-394.
    • (2002) Annu Rev Immunol , vol.20 , pp. 371-394
    • Samelson, L.E.1
  • 44
    • 0141447817 scopus 로고    scopus 로고
    • T-cell receptor signal transmission: Who gives an ITAM?
    • Pitcher, LA and van Oers, NS (2003) T-cell receptor signal transmission: Who gives an ITAM?. Trends Immunol, 24:10, pp. 554-560.
    • (2003) Trends Immunol , vol.24 , Issue.10 , pp. 554-560
    • Pitcher, L.A.1    van Oers, N.S.2
  • 45
    • 0024980981 scopus 로고
    • Antigen receptor tail clue
    • Reth, M. (1989) Antigen receptor tail clue. Nature, 338:6214, pp. 383-384.
    • (1989) Nature , vol.338 , Issue.6214 , pp. 383-384
    • Reth, M.1
  • 46
    • 34247871586 scopus 로고    scopus 로고
    • The expanding role for ITAM-based signaling pathways in immune cells
    • Abram, CL and Lowell, CA (2007) The expanding role for ITAM-based signaling pathways in immune cells. Sci STKE, 2007:377, p. re2.
    • (2007) Sci STKE , vol.2007 , Issue.377 , pp. 2
    • Abram, C.L.1    Lowell, C.A.2
  • 48
    • 11144355389 scopus 로고    scopus 로고
    • The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase
    • Mocsai, A., Humphrey, MB, Van Ziffle, JA, Hu, Y., Burghardt, A., Spusta, SC, Majumdar, S., Lanier, LL, Lowell, CA and Nakamura, MC (2004) The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase. Proc Natl Acad Sci USA, 101:16, pp. 6158-6163.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.16 , pp. 6158-6163
    • Mocsai, A.1    Humphrey, M.B.2    Van Ziffle, J.A.3    Hu, Y.4    Burghardt, A.5    Spusta, S.C.6    Majumdar, S.7    Lanier, L.L.8    Lowell, C.A.9    Nakamura, M.C.10
  • 49
    • 0345448261 scopus 로고    scopus 로고
    • High dose M-CSF partially rescues the Dap12-/-osteoclast phenotype
    • Faccio, R., Zou, W., Colaianni, G., Teitelbaum, SL and Ross, FP (2003) High dose M-CSF partially rescues the Dap12-/-osteoclast phenotype. J Cell Biochem, 90:5, pp. 871-883.
    • (2003) J Cell Biochem , vol.90 , Issue.5 , pp. 871-883
    • Faccio, R.1    Zou, W.2    Colaianni, G.3    Teitelbaum, S.L.4    Ross, F.P.5
  • 50
    • 0034503091 scopus 로고    scopus 로고
    • The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function
    • Lanier, LL and Bakker, AB (2000) The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function. Immunol Today, 21:12, pp. 611-614.
    • (2000) Immunol Today , vol.21 , Issue.12 , pp. 611-614
    • Lanier, L.L.1    Bakker, A.B.2
  • 51
    • 0028042424 scopus 로고
    • FcR gamma chain deletion results in pleiotrophic effector cell defects
    • Takai, T., Li, M., Sylvestre, D., Clynes, R. and Ravetch, JV (1994) FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell, 76:3, pp. 519-529.
    • (1994) Cell , vol.76 , Issue.3 , pp. 519-529
    • Takai, T.1    Li, M.2    Sylvestre, D.3    Clynes, R.4    Ravetch, J.V.5
  • 54
    • 0033305156 scopus 로고    scopus 로고
    • Characterization of immortalized osteoclast precursors developed from mice transgenic for both bcl-X(L) and simian virus 40 large T antigen
    • Hentunen, TA, Jackson, SH, Chung, H., Reddy, SV, Lorenzo, J., Choi, SJ and Roodman, GD (1999) Characterization of immortalized osteoclast precursors developed from mice transgenic for both bcl-X(L) and simian virus 40 large T antigen. Endocrinology, 140:7, pp. 2954-2961.
    • (1999) Endocrinology , vol.140 , Issue.7 , pp. 2954-2961
    • Hentunen, T.A.1    Jackson, S.H.2    Chung, H.3    Reddy, S.V.4    Lorenzo, J.5    Choi, S.J.6    Roodman, G.D.7
  • 55
    • 0025641887 scopus 로고
    • Immunophenotypic differences between osteoclasts and macrophage polykaryons: Immunohistological distinction and implications for osteoclast ontogeny and function
    • Athanasou, NA and Quinn, J. (1990) Immunophenotypic differences between osteoclasts and macrophage polykaryons: Immunohistological distinction and implications for osteoclast ontogeny and function. J Clin Pathol, 43:12, pp. 997-1003.
    • (1990) J Clin Pathol , vol.43 , Issue.12 , pp. 997-1003
    • Athanasou, N.A.1    Quinn, J.2
  • 56
    • 0032494114 scopus 로고    scopus 로고
    • Paired immunoglobulin-like receptor (PIR)-A is involved in activating mast cells through its association with Fc receptor gamma chain
    • Maeda, A., Kurosaki, M. and Kurosaki, T. (1998) Paired immunoglobulin-like receptor (PIR)-A is involved in activating mast cells through its association with Fc receptor gamma chain. J Exp Med, 188:5, pp. 991-995.
    • (1998) J Exp Med , vol.188 , Issue.5 , pp. 991-995
    • Maeda, A.1    Kurosaki, M.2    Kurosaki, T.3
  • 57
    • 0033181323 scopus 로고    scopus 로고
    • Functional association of FcepsilonRIgamma with arginine(632) of paired immunoglobulin-like receptor (PIR)-A3 in murine macrophages
    • Taylor, LS and McVicar, DW (1999) Functional association of FcepsilonRIgamma with arginine(632) of paired immunoglobulin-like receptor (PIR)-A3 in murine macrophages. Blood, 94:5, pp. 1790-1796.
    • (1999) Blood , vol.94 , Issue.5 , pp. 1790-1796
    • Taylor, L.S.1    McVicar, D.W.2
  • 58
    • 4444256188 scopus 로고    scopus 로고
    • OSCAR is an FcRgamma-associated receptor that is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells
    • Merck, E., Gaillard, C., Gorman, DM, Montero-Julian, F., Durand, I., Zurawski, SM, Menetrier-Caux, C., Carra, G., Lebecque, S. and Trinchieri, G. (2004) OSCAR is an FcRgamma-associated receptor that is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells. Blood, 104:5, pp. 1386-1395.
    • (2004) Blood , vol.104 , Issue.5 , pp. 1386-1395
    • Merck, E.1    Gaillard, C.2    Gorman, D.M.3    Montero-Julian, F.4    Durand, I.5    Zurawski, S.M.6    Menetrier-Caux, C.7    Carra, G.8    Lebecque, S.9    Trinchieri, G.10
  • 59
    • 3242665399 scopus 로고    scopus 로고
    • Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR)
    • Ishikawa, S., Arase, N., Suenaga, T., Saita, Y., Noda, M., Kuriyama, T., Arase, H. and Saito, T. (2004) Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR). Int Immunol, 16:7, pp. 1019-1025.
    • (2004) Int Immunol , vol.16 , Issue.7 , pp. 1019-1025
    • Ishikawa, S.1    Arase, N.2    Suenaga, T.3    Saita, Y.4    Noda, M.5    Kuriyama, T.6    Arase, H.7    Saito, T.8
  • 60
    • 0037148508 scopus 로고    scopus 로고
    • A novel member of the leukocyte receptor complex regulates osteoclast differentiation
    • Kim, N., Takami, M., Rho, J., Josien, R. and Choi, Y. (2002) A novel member of the leukocyte receptor complex regulates osteoclast differentiation. J Exp Med, 195:2, pp. 201-209.
    • (2002) J Exp Med , vol.195 , Issue.2 , pp. 201-209
    • Kim, N.1    Takami, M.2    Rho, J.3    Josien, R.4    Choi, Y.5
  • 61
    • 18244372456 scopus 로고    scopus 로고
    • Fc receptor gamma-chain activation via hOSCAR induces survival and maturation of dendritic cells and modulates Toll-like receptor responses
    • Merck, E., de Saint-Vis, B., Scuiller, M., Gaillard, C., Caux, C., Trinchieri, G. and Bates, EE (2005) Fc receptor gamma-chain activation via hOSCAR induces survival and maturation of dendritic cells and modulates Toll-like receptor responses. Blood, 105:9, pp. 3623-3632.
    • (2005) Blood , vol.105 , Issue.9 , pp. 3623-3632
    • Merck, E.1    de Saint-Vis, B.2    Scuiller, M.3    Gaillard, C.4    Caux, C.5    Trinchieri, G.6    Bates, E.E.7
  • 65
    • 0030882883 scopus 로고    scopus 로고
    • Nasu-Hakola syndrome: Polycystic lipomembranous osteodysplasia with sclerosing leucoencephalopathy and presenile dementia
    • Verloes, A., Maquet, P., Sadzot, B., Vivario, M., Thiry, A. and Franck, G. (1997) Nasu-Hakola syndrome: Polycystic lipomembranous osteodysplasia with sclerosing leucoencephalopathy and presenile dementia. J Med Genet, 34:9, pp. 753-757.
    • (1997) J Med Genet , vol.34 , Issue.9 , pp. 753-757
    • Verloes, A.1    Maquet, P.2    Sadzot, B.3    Vivario, M.4    Thiry, A.5    Franck, G.6
  • 67
    • 0041920899 scopus 로고    scopus 로고
    • Impaired differentiation of osteoclasts in TREM-2-deficient individuals
    • Cella, M., Buonsanti, C., Strader, C., Kondo, T., Salmaggi, A. and Colonna, M. (2003) Impaired differentiation of osteoclasts in TREM-2-deficient individuals. J Exp Med, 198:4, pp. 645-651.
    • (2003) J Exp Med , vol.198 , Issue.4 , pp. 645-651
    • Cella, M.1    Buonsanti, C.2    Strader, C.3    Kondo, T.4    Salmaggi, A.5    Colonna, M.6
  • 69
    • 0034068691 scopus 로고    scopus 로고
    • Nasu-Hakola disease in two Tunisian siblings: New radiological findings
    • Chaabane, M., Larnaout, A., Sebai, R., Nagi, S., Touibi, S. and Hentati, F. (2000) Nasu-Hakola disease in two Tunisian siblings: New radiological findings. Neuroradiology, 42:5, pp. 375-378.
    • (2000) Neuroradiology , vol.42 , Issue.5 , pp. 375-378
    • Chaabane, M.1    Larnaout, A.2    Sebai, R.3    Nagi, S.4    Touibi, S.5    Hentati, F.6
  • 72
    • 20644443886 scopus 로고    scopus 로고
    • Enhanced toll-like receptor responses in the absence of signaling adaptor DAP12
    • Hamerman, JA, Tchao, NK, Lowell, CA and Lanier, LL (2005) Enhanced toll-like receptor responses in the absence of signaling adaptor DAP12. Nat Immunol, 6:6, pp. 579-586.
    • (2005) Nat Immunol , vol.6 , Issue.6 , pp. 579-586
    • Hamerman, J.A.1    Tchao, N.K.2    Lowell, C.A.3    Lanier, L.L.4
  • 73
    • 33746875981 scopus 로고    scopus 로고
    • Cutting edge: Inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12
    • Hamerman, JA, Jarjoura, JR, Humphrey, MB, Nakamura, MC, Seaman, WE and Lanier, LL (2006) Cutting edge: Inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12. J Immunol, 177:4, pp. 2051-2055.
    • (2006) J Immunol , vol.177 , Issue.4 , pp. 2051-2055
    • Hamerman, J.A.1    Jarjoura, J.R.2    Humphrey, M.B.3    Nakamura, M.C.4    Seaman, W.E.5    Lanier, L.L.6
  • 75
    • 33846316333 scopus 로고    scopus 로고
    • The TREM receptor family and signal integration
    • Klesney-Tait, J., Turnbull, IR and Colonna, M. (2006) The TREM receptor family and signal integration. Nat Immunol, 7:12, pp. 1266-1273.
    • (2006) Nat Immunol , vol.7 , Issue.12 , pp. 1266-1273
    • Klesney-Tait, J.1    Turnbull, I.R.2    Colonna, M.3
  • 76
    • 33644860951 scopus 로고    scopus 로고
    • Inhibition of immune responses by ITAM-bearing receptors
    • Hamerman, JA and Lanier, LL (2006) Inhibition of immune responses by ITAM-bearing receptors. Sci STKE, 2006:320, p. re1.
    • (2006) Sci STKE , vol.2006 , Issue.320 , pp. 1
    • Hamerman, J.A.1    Lanier, L.L.2
  • 77
    • 33846562134 scopus 로고    scopus 로고
    • Activating and inhibitory functions of DAP12
    • Turnbull, IR and Colonna, M. (2007) Activating and inhibitory functions of DAP12. Nat Rev Immunol, 7:2, pp. 155-161.
    • (2007) Nat Rev Immunol , vol.7 , Issue.2 , pp. 155-161
    • Turnbull, I.R.1    Colonna, M.2
  • 82
  • 83
    • 0036219193 scopus 로고    scopus 로고
    • Negative regulation of immunoreceptor signaling
    • Veillette, A., Latour, S. and Davidson, D. (2002) Negative regulation of immunoreceptor signaling. Annu Rev Immunol, 20, pp. 669-707.
    • (2002) Annu Rev Immunol , vol.20 , pp. 669-707
    • Veillette, A.1    Latour, S.2    Davidson, D.3
  • 84
    • 0032816807 scopus 로고    scopus 로고
    • The tyrosine phosphatase SHP-1 is a negative regulator of osteoclastogenesis and osteoclast resorbing activity: Increased resorption and osteopenia in me(v)/me(v) mutant mice
    • Aoki, K., Didomenico, E., Sims, NA, Mukhopadhyay, K., Neff, L., Houghton, A., Amling, M., Levy, JB, Horne, WC and Baron, R. (1999) The tyrosine phosphatase SHP-1 is a negative regulator of osteoclastogenesis and osteoclast resorbing activity: Increased resorption and osteopenia in me(v)/me(v) mutant mice. Bone, 25:3, pp. 261-267.
    • (1999) Bone , vol.25 , Issue.3 , pp. 261-267
    • Aoki, K.1    Didomenico, E.2    Sims, N.A.3    Mukhopadhyay, K.4    Neff, L.5    Houghton, A.6    Amling, M.7    Levy, J.B.8    Horne, W.C.9    Baron, R.10
  • 86
    • 0032982796 scopus 로고    scopus 로고
    • Deficiency of SHP-1 protein-tyrosine phosphatase activity results in heightened osteoclast function and decreased bone density
    • Umeda, S., Beamer, WG, Takagi, K., Naito, M., Hayashi, S., Yonemitsu, H., Yi, T. and Shultz, LD (1999) Deficiency of SHP-1 protein-tyrosine phosphatase activity results in heightened osteoclast function and decreased bone density. Am J Pathol, 155:1, pp. 223-233.
    • (1999) Am J Pathol , vol.155 , Issue.1 , pp. 223-233
    • Umeda, S.1    Beamer, W.G.2    Takagi, K.3    Naito, M.4    Hayashi, S.5    Yonemitsu, H.6    Yi, T.7    Shultz, L.D.8
  • 87
    • 0345735839 scopus 로고    scopus 로고
    • CMRF-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formation
    • Chung, DH, Humphrey, MB, Nakamura, MC, Ginzinger, DG, Seaman, WE and Daws, MR (2003) CMRF-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formation. J Immunol, 171:12, pp. 6541-6548.
    • (2003) J Immunol , vol.171 , Issue.12 , pp. 6541-6548
    • Chung, D.H.1    Humphrey, M.B.2    Nakamura, M.C.3    Ginzinger, D.G.4    Seaman, W.E.5    Daws, M.R.6
  • 89
    • 0034618580 scopus 로고    scopus 로고
    • Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: Modulation of the expression by osteotropic factors and cytokines
    • Nakashima, T., Kobayashi, Y., Yamasaki, S., Kawakami, A., Eguchi, K., Sasaki, H. and Sakai, H. (2000) Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: Modulation of the expression by osteotropic factors and cytokines. Biochem Biophys Res Commun, 275:3, pp. 768-775.
    • (2000) Biochem Biophys Res Commun , vol.275 , Issue.3 , pp. 768-775
    • Nakashima, T.1    Kobayashi, Y.2    Yamasaki, S.3    Kawakami, A.4    Eguchi, K.5    Sasaki, H.6    Sakai, H.7
  • 90
    • 0034813643 scopus 로고    scopus 로고
    • Regulation of osteoprotegerin secretion from primary cultures of human bone marrow stromal cells
    • Brandstrom, H., Bjorkman, T. and Ljunggren, O. (2001) Regulation of osteoprotegerin secretion from primary cultures of human bone marrow stromal cells. Biochem Biophys Res Commun, 280:3, pp. 831-835.
    • (2001) Biochem Biophys Res Commun , vol.280 , Issue.3 , pp. 831-835
    • Brandstrom, H.1    Bjorkman, T.2    Ljunggren, O.3
  • 91
    • 0032578611 scopus 로고    scopus 로고
    • Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines
    • Hofbauer, LC, Dunstan, CR, Spelsberg, TC, Riggs, BL and Khosla, S. (1998) Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines. Biochem Biophys Res Commun, 250:3, pp. 776-781.
    • (1998) Biochem Biophys Res Commun , vol.250 , Issue.3 , pp. 776-781
    • Hofbauer, L.C.1    Dunstan, C.R.2    Spelsberg, T.C.3    Riggs, B.L.4    Khosla, S.5
  • 92
    • 0032588998 scopus 로고    scopus 로고
    • Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells
    • Hofbauer, LC, Lacey, DL, Dunstan, CR, Spelsberg, TC, Riggs, BL and Khosla, S. (1999) Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells. Bone, 25:3, pp. 255-259.
    • (1999) Bone , vol.25 , Issue.3 , pp. 255-259
    • Hofbauer, L.C.1    Lacey, D.L.2    Dunstan, C.R.3    Spelsberg, T.C.4    Riggs, B.L.5    Khosla, S.6
  • 93
    • 0042744757 scopus 로고    scopus 로고
    • IL-4 suppresses osteoclast development and mature osteoclast function by a STAT6-dependent mechanism: Irreversible inhibition of the differentiation program activated by RANKL
    • Moreno, JL, Kaczmarek, M., Keegan, AD and Tondravi, M. (2003) IL-4 suppresses osteoclast development and mature osteoclast function by a STAT6-dependent mechanism: Irreversible inhibition of the differentiation program activated by RANKL. Blood, 102:3, pp. 1078-1086.
    • (2003) Blood , vol.102 , Issue.3 , pp. 1078-1086
    • Moreno, J.L.1    Kaczmarek, M.2    Keegan, A.D.3    Tondravi, M.4
  • 95
    • 33646345862 scopus 로고    scopus 로고
    • Inhibition of hormone and cytokine-stimulated osteoclastogenesis and bone resorption by interleukin-4 and interleukin-13 is associated with increased osteoprotegerin and decreased RANKL and RANK in a STAT6-dependent pathway
    • Palmqvist, P., Lundberg, P., Persson, E., Johansson, A., Lundgren, I., Lie, A., Conaway, HH and Lerner, UH (2006) Inhibition of hormone and cytokine-stimulated osteoclastogenesis and bone resorption by interleukin-4 and interleukin-13 is associated with increased osteoprotegerin and decreased RANKL and RANK in a STAT6-dependent pathway. J Biol Chem, 281:5, pp. 2414-2429.
    • (2006) J Biol Chem , vol.281 , Issue.5 , pp. 2414-2429
    • Palmqvist, P.1    Lundberg, P.2    Persson, E.3    Johansson, A.4    Lundgren, I.5    Lie, A.6    Conaway, H.H.7    Lerner, U.H.8
  • 96
    • 0037105542 scopus 로고    scopus 로고
    • IL-6, leukemia inhibitory factor, and oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-kappa B ligand, osteoprotegerin, and receptor activator of NF-kappa B in mouse calvariae
    • Palmqvist, P., Persson, E., Conaway, HH and Lerner, UH (2002) IL-6, leukemia inhibitory factor, and oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-kappa B ligand, osteoprotegerin, and receptor activator of NF-kappa B in mouse calvariae. J Immunol, 169:6, pp. 3353-3362.
    • (2002) J Immunol , vol.169 , Issue.6 , pp. 3353-3362
    • Palmqvist, P.1    Persson, E.2    Conaway, H.H.3    Lerner, U.H.4
  • 97
    • 0031735152 scopus 로고    scopus 로고
    • Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells
    • Horwood, NJ, Elliott, J., Martin, TJ and Gillespie, MT (1998) Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells. Endocrinology, 139:11, pp. 4743-4746.
    • (1998) Endocrinology , vol.139 , Issue.11 , pp. 4743-4746
    • Horwood, N.J.1    Elliott, J.2    Martin, T.J.3    Gillespie, M.T.4
  • 98
    • 0036312825 scopus 로고    scopus 로고
    • Characterization of the bone-resorptive effect of interleukin-11 in cultured mouse calvarial bones
    • Ahlen, J., Andersson, S., Mukohyama, H., Roth, C., Backman, A., Conaway, HH and Lerner, UH (2002) Characterization of the bone-resorptive effect of interleukin-11 in cultured mouse calvarial bones. Bone, 31:1, pp. 242-251.
    • (2002) Bone , vol.31 , Issue.1 , pp. 242-251
    • Ahlen, J.1    Andersson, S.2    Mukohyama, H.3    Roth, C.4    Backman, A.5    Conaway, H.H.6    Lerner, U.H.7
  • 99
    • 0141527491 scopus 로고    scopus 로고
    • Inhibition of RANKL-induced osteoclast formation in mouse bone marrow cells by IL-12: Involvement of IFN-gamma possibly induced from non-T cell population
    • Nagata, N., Kitaura, H., Yoshida, N. and Nakayama, K. (2003) Inhibition of RANKL-induced osteoclast formation in mouse bone marrow cells by IL-12: Involvement of IFN-gamma possibly induced from non-T cell population. Bone, 33:4, pp. 721-732.
    • (2003) Bone , vol.33 , Issue.4 , pp. 721-732
    • Nagata, N.1    Kitaura, H.2    Yoshida, N.3    Nakayama, K.4
  • 101
    • 7244236472 scopus 로고    scopus 로고
    • Interleukin (IL)18 stimulates osteoclast formation through synovial T cells in rheumatoid arthritis: Comparison with IL1 beta and tumour necrosis factor alpha
    • Dai, SM, Nishioka, K. and Yudoh, K. (2004) Interleukin (IL)18 stimulates osteoclast formation through synovial T cells in rheumatoid arthritis: Comparison with IL1 beta and tumour necrosis factor alpha. Ann Rheum Dis, 63:11, pp. 1379-1386.
    • (2004) Ann Rheum Dis , vol.63 , Issue.11 , pp. 1379-1386
    • Dai, S.M.1    Nishioka, K.2    Yudoh, K.3
  • 102
    • 34247581650 scopus 로고    scopus 로고
    • Signaling crosstalk between RANKL and interferons in osteoclast differentiation
    • Takayanagi, H., Kim, S. and Taniguchi, T. (2002) Signaling crosstalk between RANKL and interferons in osteoclast differentiation. Arthritis Res, 4, pp. S227-S232.
    • (2002) Arthritis Res , vol.4 , pp. 227-232
    • Takayanagi, H.1    Kim, S.2    Taniguchi, T.3
  • 103
    • 0034835405 scopus 로고    scopus 로고
    • Regulation of osteoclastogenesis and RANK expression by TGF-beta1
    • Yan, T., Riggs, BL, Boyle, WJ and Khosla, S. (2001) Regulation of osteoclastogenesis and RANK expression by TGF-beta1. J Cell Biochem, 83:2, pp. 320-325.
    • (2001) J Cell Biochem , vol.83 , Issue.2 , pp. 320-325
    • Yan, T.1    Riggs, B.L.2    Boyle, W.J.3    Khosla, S.4
  • 105
    • 0037135568 scopus 로고    scopus 로고
    • Transforming growth factor-beta induces expression of receptor activator of NF-kappa B ligand in vascular endothelial cells derived from bone
    • Ishida, A., Fujita, N., Kitazawa, R. and Tsuruo, T. (2002) Transforming growth factor-beta induces expression of receptor activator of NF-kappa B ligand in vascular endothelial cells derived from bone. J Biol Chem, 277:29, pp. 26217-26224.
    • (2002) J Biol Chem , vol.277 , Issue.29 , pp. 26217-26224
    • Ishida, A.1    Fujita, N.2    Kitazawa, R.3    Tsuruo, T.4
  • 106
    • 0035965326 scopus 로고    scopus 로고
    • Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta)
    • Thirunavukkarasu, K., Miles, RR, Halladay, DL, Yang, X., Galvin, RJ, Chandrasekhar, S., Martin, TJ and Onyia, JE (2001) Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects. J Biol Chem, 276:39, pp. 36241-36250.
    • (2001) J Biol Chem , vol.276 , Issue.39 , pp. 36241-36250
    • Thirunavukkarasu, K.1    Miles, R.R.2    Halladay, D.L.3    Yang, X.4    Galvin, R.J.5    Chandrasekhar, S.6    Martin, T.J.7    Onyia, J.E.8
  • 107
    • 0037398261 scopus 로고    scopus 로고
    • Role of RANK ligand in mediating increased bone resorption in early postmenopausal women
    • Eghbali-Fatourechi, G., Khosla, S., Sanyal, A., Boyle, WJ, Lacey, DL and Riggs, BL (2003) Role of RANK ligand in mediating increased bone resorption in early postmenopausal women. J Clin Invest, 111:8, pp. 1221-1230.
    • (2003) J Clin Invest , vol.111 , Issue.8 , pp. 1221-1230
    • Eghbali-Fatourechi, G.1    Khosla, S.2    Sanyal, A.3    Boyle, W.J.4    Lacey, D.L.5    Riggs, B.L.6
  • 108
    • 0033304632 scopus 로고    scopus 로고
    • Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells
    • Hofbauer, LC, Khosla, S., Dunstan, CR, Lacey, DL, Spelsberg, TC and Riggs, BL (1999) Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells. Endocrinology, 140:9, pp. 4367-4370.
    • (1999) Endocrinology , vol.140 , Issue.9 , pp. 4367-4370
    • Hofbauer, L.C.1    Khosla, S.2    Dunstan, C.R.3    Lacey, D.L.4    Spelsberg, T.C.5    Riggs, B.L.6
  • 109
    • 0009660825 scopus 로고    scopus 로고
    • Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): A mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro
    • Yasuda, H., Shima, N., Nakagawa, N., Mochizuki, SI, Yano, K., Fujise, N., Sato, Y., Goto, M., Yamaguchi, K. and Kuriyama, M. (1998) Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): A mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro. Endocrinology, 139:3, pp. 1329-1337.
    • (1998) Endocrinology , vol.139 , Issue.3 , pp. 1329-1337
    • Yasuda, H.1    Shima, N.2    Nakagawa, N.3    Mochizuki, S.I.4    Yano, K.5    Fujise, N.6    Sato, Y.7    Goto, M.8    Yamaguchi, K.9    Kuriyama, M.10
  • 110
    • 0031721590 scopus 로고    scopus 로고
    • Osteoprotegerin mRNA is expressed in primary human osteoblast-like cells: Down-regulation by glucocorticoids
    • Vidal, NO, Brandstrom, H., Jonsson, KB and Ohlsson, C. (1998) Osteoprotegerin mRNA is expressed in primary human osteoblast-like cells: Down-regulation by glucocorticoids. J Endocrinol, 159:1, pp. 191-195.
    • (1998) J Endocrinol , vol.159 , Issue.1 , pp. 191-195
    • Vidal, N.O.1    Brandstrom, H.2    Jonsson, K.B.3    Ohlsson, C.4
  • 111
    • 0033305046 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: Correlation with osteoclast-like cell formation
    • Lee, SK and Lorenzo, JA (1999) Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: Correlation with osteoclast-like cell formation. Endocrinology, 140:8, pp. 3552-3561.
    • (1999) Endocrinology , vol.140 , Issue.8 , pp. 3552-3561
    • Lee, S.K.1    Lorenzo, J.A.2
  • 115
    • 15444362701 scopus 로고    scopus 로고
    • Cross-talk between the interleukin-6 and prostaglandin E(2) signaling systems results in enhancement of osteoclastogenesis through effects on the osteoprotegerin/receptor activator of nuclear factor-{kappa}B (RANK) ligand/RANK system
    • Liu, XH, Kirschenbaum, A., Yao, S. and Levine, AC (2005) Cross-talk between the interleukin-6 and prostaglandin E(2) signaling systems results in enhancement of osteoclastogenesis through effects on the osteoprotegerin/receptor activator of nuclear factor-{kappa}B (RANK) ligand/RANK system. Endocrinology, 146:4, pp. 1991-1998.
    • (2005) Endocrinology , vol.146 , Issue.4 , pp. 1991-1998
    • Liu, X.H.1    Kirschenbaum, A.2    Yao, S.3    Levine, A.C.4
  • 116
    • 0842343433 scopus 로고    scopus 로고
    • Suppression of osteoprotegerin expression by prostaglandin E2 is crucially involved in lipopolysaccharide-induced osteoclast formation
    • Suda, K., Udagawa, N., Sato, N., Takami, M., Itoh, K., Woo, JT, Takahashi, N. and Nagai, K. (2004) Suppression of osteoprotegerin expression by prostaglandin E2 is crucially involved in lipopolysaccharide-induced osteoclast formation. J Immunol, 172:4, pp. 2504-2510.
    • (2004) J Immunol , vol.172 , Issue.4 , pp. 2504-2510
    • Suda, K.1    Udagawa, N.2    Sato, N.3    Takami, M.4    Itoh, K.5    Woo, J.T.6    Takahashi, N.7    Nagai, K.8
  • 119
    • 34250783897 scopus 로고    scopus 로고
    • Novel osteoclast signaling mechanisms
    • Shinohara, M. and Takayanagi, H. (2007) Novel osteoclast signaling mechanisms. Curr Osteoporos Rep, 5:2, pp. 67-72.
    • (2007) Curr Osteoporos Rep , vol.5 , Issue.2 , pp. 67-72
    • Shinohara, M.1    Takayanagi, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.