The tyrosine phosphatase SHP-1 is a negative regulator of osteoclastogenesis and osteoclast resorbing activity: Increased resorption and osteopenia in me(v)/me(v) mutant mice

Bone

Volumn 25, Issue 3, 1999, Pages 261-267

  Aoki, K ^a   Didomenico, E ^a,b   Sims, N A ^a,b   Mukhopadhyay, K ^a,b   Neff, L ^a,b   Houghton, A ^a,b   Amling, M ^a,b   Levy, J B ^a,b   Horne, W C ^a,b   Baron, R ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE CANCER CENTER   (United States)

Author keywords

Motheaten; Osteoclast function; Osteoclastogenesis; Osteopenia; Src homology 2 domain containing tyrosine phosphatase 1(SHP 1)

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; IN VITRO STUDY; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; OSTEOPENIA; PROTEIN PHOSPHORYLATION; SEQUENCE HOMOLOGY; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; BONE DISEASES, METABOLIC; BONE MARROW CELLS; BONE RESORPTION; CELLS, CULTURED; COCULTURE TECHNIQUES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; OSTEOCLASTS; PROTEIN-TYROSINE-PHOSPHATASE; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION; SKULL; SPLEEN; SRC HOMOLOGY DOMAINS; TIBIA;

EID: 0032816807     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(99)00174-X     Document Type: Article

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