Treatment with siRNA and antisense oligonucleotides targeted to HIF-1α induced apoptosis in human tongue squamous cell carcinomas

International Journal of Cancer

Volumn 111, Issue 6, 2004, Pages 849-857

  Zhang, Qunzhou ^a   Zhang, Zuo Feng ^b   Rao, Jian Y ^c   Sato, J Denry ^d   Brown, Jimmy ^a   Messadi, Diana V ^e   Le, Anh D ^a,e  

^a CHARLES R DREW UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d MOUNT DESERT ISLAND BIOLOGICAL LABORATORY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antisense; Apoptosis; Bcl 2; HIF 1 ; IAP 2; siRNA

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CASPASE 3; GENE PRODUCT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IAP 2 PROTEIN; PROTEIN; PROTEIN BCL 2; PROTEIN P53; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER GROWTH; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; KNOCKOUT GENE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSCRIPTION; SQUAMOUS CELL CARCINOMA; TONGUE CARCINOMA;

APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CELL HYPOXIA; CELL SURVIVAL; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; OLIGONUCLEOTIDES, ANTISENSE; PHENOTYPE; RNA, MESSENGER; RNA, SMALL INTERFERING; TONGUE NEOPLASMS; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 4143076004     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20334     Document Type: Article

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