Cyclooxygenase-2 pathway as a potential therapeutic target in diabetic peripheral neuropathy

Current Drug Targets

Volumn 9, Issue 1, 2008, Pages 68-76

  Kellogg, Aaron P ^a   Cheng, Hsinlin Thomas ^a   Pop Busui, Rodica ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Cyclooxygenase 2; Diabetes; Diabetic peripheral neuropathy; Inflammation; Oxidative stress; Prostaglandins

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; CYCLOOXYGENASE 3; DICLOFENAC; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUMIRACOXIB; MELOXICAM; NAPROXEN; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PARECOXIB; PLACEBO; ROFECOXIB; TUMOR NECROSIS FACTOR ALPHA; VALDECOXIB;

ALZHEIMER DISEASE; ANALGESIA; ANKYLOSING SPONDYLITIS; ANTIINFLAMMATORY ACTIVITY; ANTIPYRETIC ACTIVITY; ARTHRITIS; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; DIABETES MELLITUS; DIABETIC NEUROPATHY; DIGESTIVE SYSTEM ULCER; DRUG MEGADOSE; DRUG SAFETY; DRUG STRUCTURE; DRUG TARGETING; DRUG WITHDRAWAL; DYSPEPSIA; ENZYME ACTIVATION; GASTROINTESTINAL HEMORRHAGE; GASTROINTESTINAL OBSTRUCTION; GENETIC POLYMORPHISM; HEART DEATH; HEART INFARCTION; HOMOZYGOSITY; HUMAN; HYPERTENSION; IC 50; INFLAMMATION; LOW BACK PAIN; NEUROPATHIC PAIN; NEUROPROTECTION; NONHUMAN; OSTEOARTHRITIS; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; QUALITY OF LIFE; REVIEW; RHEUMATOID ARTHRITIS; SIDE EFFECT; STROKE; SYSTOLIC BLOOD PRESSURE; THROMBOCYTE DYSFUNCTION; VASOCONSTRICTION; VASODILATATION;

ANIMALS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIABETIC NEUROPATHIES; DRUG DELIVERY SYSTEMS; HUMANS; OXIDATIVE STRESS; UP-REGULATION;

EID: 38849140877     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945008783431691     Document Type: Review

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