Spinal cyclooxygenase-2 is involved in development of allodynia after nerve injury in rats

Neuroscience

Volumn 97, Issue 4, 2000, Pages 743-748

  Zhao, Z ^a   Chen, S R ^a   Eisenach, J C ^a   Busija, D W ^a   Pan, H L ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Indomethacin; Neuronal plasticity; Neuropathic pain; Prostaglandins; Spinal cord; Thalamus

Indexed keywords

CYCLOOXYGENASE 2;

ALLODYNIA; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; MALE; NERVE CELL PLASTICITY; NERVE INJURY; NERVE LIGATION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD; THALAMUS;

ANIMALS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GYRUS CINGULI; INDOMETHACIN; INJECTIONS, SPINAL; ISOENZYMES; LOCUS COERULEUS; MALE; MEMBRANE PROTEINS; PAIN; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; SPINAL CORD; SPINAL NERVES; THALAMUS; TIME FACTORS;

EID: 0034118112     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00052-X     Document Type: Article

References (46)

1. Arner S., Meyerson B.A. Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain. Pain. 33:1988;11-23.
2. Beiche F., Scheuerer S., Brune K., Geisslinger G., Goppelt-Struebe M. Up-regulation of cyclooxygenase-2 mRNA in the rat spinal cord following peripheral inflammation. Fedn Eur. biochem. Socs Lett. 390:1996;165-169.
3. Breder C.D., Dewitt D., Kraig R.P. Characterization of inducible cyclooxygenase in rat brain. J. comp. Neurol. 355:1995;296-315.
4. Breder C.D., Smith W.L., Raz A., Masferrer J., Seibert K., Needleman P., Saper C.B. Distribution and characterization of cyclooxygenase immunoreactivity in the ovine brain. J. comp. Neurol. 322:1992;409-438.
5. Chaplan S.R., Bach F.W., Pogrel J.W., Chung J.M., Yaksh T.L. Quantitative assessment of tactile allodynia in the rat paw. J. Neurosci. Meth. 53:1994;55-63.
6. Chapman V., Dickenson A.H. The spinal and peripheral roles of bradykinin and prostaglandins in nociceptive processing in the rat. Eur. J. Pharmac. 219:1992;427-433.
7. Craig A.D., Bushnell M.C., Zhang E.T., Blomqvist A. A thalamic nucleus specific for pain and temperature sensation. Nature. 372:1994;770-773.
8. Davar G., Hama A., Deykin A., Vos B., Maciewicz R. MK-801 blocks the development of thermal hyperalgesia in a rat model of experimental painful neuropathy. Brain Res. 553:1991;327-330.
9. Dirig D.M., Isakson P.C., Yaksh T.L. Effect of COX-1 and COX-2 inhibition on induction and maintenance of carrageenan-evoked thermal hyperalgesia in rats. J. Pharmac. exp. Ther. 285:1998;1031-1038.
10. Dolan S., Nolan A.M. N-Methyl-D-aspartate induced mechanical allodynia is blocked by nitric oxide synthase and cyclooxygenase-2 inhibitors. NeuroReport. 10:1999;449-452.
11. Domoki F., Veltkamp R., Thrikawala N., Robins G., Bari F., Louis T.M., Busija D.W. Ischemia-reperfusion rapidly increases COX-2 expression in piglet cerebral arteries. Am. J. Physiol. 277:1999;H1207-1214.
12. Dubois R.N., Abramson S.B., Crofford L., Gupta R.A., Simon L.S., Van De Putte L.B., Lipsky P.E. Cyclooxygenase in biology and disease. Fedn Am. Socs exp. Biol. J. 12:1998;1063-1073.
13. Feng L., Sun W., Xia Y., Tang W.W., Chanmugam P., Soyoola E., Wilson C.B., Hwang D. Cloning two isoforms of rat cyclooxygenase: differential regulation of their expression. Archs Biochem. Biophys. 307:1993;361-368.
14. Gierse J.K., McDonald J.J., Hauser S.D., Rangwala S.H., Koboldt C.M., Seibert K. A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors. J. biol. Chem. 271:1996;15,810-15,814.
15. + current in rat sensory neurons in vitro. Neurosci. Lett. 212:1996;83-86.
16. Gracely R.H., Lynch S.A., Bennett G.J. Painful neuropathy: altered central processing maintained dynamically by peripheral input. Pain. 51:1992;175-194.
17. Hay C.H., Trevethick M.A., Wheeldon A., Bowers J.S., de Belleroche J.S. The potential role of spinal cord cyclooxygenase-2 in the development of Freund's complete adjuvant-induced changes in hyperalgesia and allodynia. Neuroscience. 78:1997;843-850.
18. Hingtgen C.M., Vasko M.R. Prostacyclin enhances the evoked-release of substance P and calcitonin gene-related peptide from rat sensory neurons. Brain Res. 655:1994;51-60.
19. Hirata H., Aston-Jones G. A novel long-latency response of locus coeruleus neurons to noxious stimuli: mediation by peripheral C-fibers. J. Neurophysiol. 71:1994;1752-1761.
20. Ichitani Y., Shi T., Haeggstrom J.Z., Samuelsson B., Hokfelt T. Increased levels of cyclooxygenase-2 mRNA in the rat spinal cord after peripheral inflammation: an in situ hybridization study. NeuroReport. 8:1997;2949-2952.
21. Kaufmann W.E., Worley P.F., Pegg J., Bremer M., Isakson P. COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex. Proc. natn. Acad. Sci. U.S.A. 93:1996;2317-2321.
22. Kim K.J., Yoon Y.W., Chung J.M. Comparison of three rodent neuropathic pain models. Expl Brain Res. 113:1997;200-206.
23. Kim S.H., Chung J.M. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain. 50:1992;355-363.
24. Lashbrook J.M., Ossipov M.H., Hunter J.C., Raffa R.B., Tallarida R.J., Porreca F. Synergistic antiallodynic effects of spinal morphine with ketorolac and selective COX1- and COX2-inhibitors in nerve-injured rats. Pain. 82:1999;65-72.
25. MacFarlane B.V., Wright A., O'Callaghan J., Benson H.A. Chronic neuropathic pain and its control by drugs. Pharmac. Ther. 75:1997;1-19.
26. Malmberg A.B., Yaksh T.L. Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition. Science. 257:1992;1276-1279.
27. Marriott D., Wilkin G.P., Coote P.R., Wood J.N. Eicosanoid synthesis by spinal cord astrocytes is evoked by substance P; possible implications for nociception and pain. Adv. Prostaglandin Thromboxane Leukot. Res. 21B:1991;739-741.
28. Nicol G.D., Klingberg D.K., Vasko M.R. Prostaglandin E2 increases calcium conductance and stimulates release of substance P in avian sensory neurons. J. Neurosci. 12:1992;1917-1927.
29. Pan H.L., Chen S.R., Eisenach J.C. Role of spinal NO in antiallodynic effect of intrathecal clonidine in neuropathic rats. Anesthesiology. 89:1998;1518-1523.
30. Parris W.C., Janicki P.K., Johnson B. Jr, Horn J.L. Intrathecal ketorolac tromethamine produces analgesia after chronic constriction injury of sciatic nerve in rat. Can. J. Anaesth. 43:1996;867-870.
31. Peri K.G., Hardy P., Li D.Y., Varma D.R., Chemtob S. Prostaglandin G/H synthase-2 is a major contributor of brain prostaglandins in the newborn. J. biol. Chem. 270:1995;24,615-24,620.
32. Pomerantz K.B., Summers B., Hajjar D.P. Eicosanoid metabolism in cholesterol-enriched arterial smooth muscle cells. Evidence for reduced posttranscriptional processing of cyclooxygenase I and reduced cyclooxygenase II gene expression. Biochemistry. 32:1993;13624-13635.
33. Seibert K., Zhang Y., Leahy K., Hauser S., Masferrer J., Perkins W., Lee L., Isakson P. Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc. natn. Acad. Sci. U.S.A. 91:1994;12,013-12,017.
34. Smith G.D., Wiseman J., Harrison S.M., Elliott P.J., Birch P.J. Pre treatment with MK-801, a non-competitive NMDA antagonist, prevents development of mechanical hyperalgesia in a rat model of chronic neuropathy, but not in a model of chronic inflammation. Neurosci. Lett. 165:1994;79-83.
35. Soliven B., Takeda M., Shandy T., Nelson D.J. Arachidonic acid and its metabolites increase Cai in cultured rat oligodendrocytes. Am. J. Physiol. 264:1993;C632-640.
36. Talbot J.D., Marrett S., Evans A.C., Meyer E., Bushnell M.C., Duncan G.H. Multiple representations of pain in human cerebral cortex. Science. 251:1991;1355-1358.
37. Uda R., Horiguchi S., Ito S., Hyodo M., Hayaishi O. Nociceptive effects induced by intrathecal administration of prostaglandin D2, E2, or F2 alpha to conscious mice. Brain Res. 510:1990;26-32.
38. Vane J.R., Botting R.M. Mechanism of action of nonsteroidal anti-inflammatory drugs. Am. J. Med. 104:1998;2S-8S.
39. Vasko M.R. Prostaglandin-induced neuropeptide release from spinal cord. Prog. Brain Res. 104:1995;367-380.
40. Willingale H.L., Gardiner N.J., McLymont N., Giblett S., Grubb B.D. Prostanoids synthesized by cyclo-oxygenase isoforms in rat spinal cord and their contribution to the development of neuronal hyperexcitability. Br. J. Pharmac. 122:1997;1593-1604.
41. Wolfe L.S., Coceani F. The role of prostaglandins in the central nervous system. A. Rev. Physiol. 41:1979;669-684.
42. Wong C.S., Cherng C.H., Tung C.S. Intrathecal administration of excitatory amino acid receptor antagonists or nitric oxide synthase inhibitor reduced autotomy behavior in rats. Anesth. Analg. 87:1998;605-608.
43. Yaksh T.L., Malmberg A.B. Spinal actions of NSAIDs in blocking spinally mediated hyperalgesia: the role of cyclooxygenase products. Agents Actions Suppl. 41:1993;89-100.
44. Yamagata K., Andreasson K.I., Kaufmann W.E., Barnes C.A., Worley P.F. Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron. 11:1993;371-386.
45. Yamamoto T., Nozaki-Taguchi N. Analysis of the effects of cyclooxygenase (COX)-1 and COX-2 in spinal nociceptive transmission using indomethacin, a non-selective COX inhibitor, and NS-398, a COX-2 selective inhibitor. Brain Res. 739:1996;104-110.
46. Yamamoto T., Shimoyama N. Role of nitric oxide in the development of thermal hyperesthesia induced by sciatic nerve constriction injury in the rat. Anesthesiology. 82:1995;1266-1273.