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Volumn 73, Issue 5, 1999, Pages 2206-2213

Interleukin-1β induces substance P release from primary afferent neurons through the cyclooxygenase-2 system

Author keywords

Cyclooxygenase 2; Dorsal root ganglion cells; Interleukin 1 receptor antagonist; Interleukin 1 ; NS 398; Substance P

Indexed keywords

CYCLOOXYGENASE 2; DEXAMETHASONE; INDOMETACIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; PROSTAGLANDIN SYNTHASE INHIBITOR; SUBSTANCE P; CYCLOOXYGENASE 2 INHIBITOR; EGTAZIC ACID; GLUCOCORTICOID; IL1RN PROTEIN, MOUSE; INTERLEUKIN 1; ISOENZYME; MESSENGER RNA; PREPROTACHYKININ; PROSTAGLANDIN SYNTHASE; PROTEIN PRECURSOR; RECOMBINANT PROTEIN; SIALOGLYCOPROTEIN; TACHYKININ;

EID: 0032589741     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.02206.x     Document Type: Article
Times cited : (171)

References (52)
  • 1
    • 0032167604 scopus 로고    scopus 로고
    • Novel regulation of cyclooxygenase-2 expression and prostaglandin E2 production by IFN-γ in human macrophages
    • Barrios-Rodiles M., and Chadee K. (1998) Novel regulation of cyclooxygenase-2 expression and prostaglandin E2 production by IFN-γ in human macrophages. J. Immunol. 161, 2441-2448.
    • (1998) J. Immunol. , vol.161 , pp. 2441-2448
    • Barrios-Rodiles, M.1    Chadee, K.2
  • 2
    • 0032516793 scopus 로고    scopus 로고
    • Localization of cyclooxygenase-2 and prostaglandin E2 receptor EP3 in the rat lumbar spinal cord
    • Beiche F., Klein T., Nusing R., Neuhuber W., and Goppelt-Struebe M. (1998) Localization of cyclooxygenase-2 and prostaglandin E2 receptor EP3 in the rat lumbar spinal cord. J. Neuroimmunol. 89, 26-34.
    • (1998) J. Neuroimmunol. , vol.89 , pp. 26-34
    • Beiche, F.1    Klein, T.2    Nusing, R.3    Neuhuber, W.4    Goppelt-Struebe, M.5
  • 3
    • 0032530997 scopus 로고    scopus 로고
    • Interleukin-1 and nociception in the rat
    • Bianchi M., Dib B., and Panerai A. E. (1998) Interleukin-1 and nociception in the rat. J. Neurosci. Res. 53, 645-650.
    • (1998) J. Neurosci. Res. , vol.53 , pp. 645-650
    • Bianchi, M.1    Dib, B.2    Panerai, A.E.3
  • 4
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction
    • Chomczynski P. and Sacchi N. (1987) Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 5
    • 0028213334 scopus 로고
    • Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues: Effects of interleukin-1β, phorbol ester, and corticosteroids
    • Crofford L. J., Wilder R. L., Ristimäki A. P., Sano H., Remmers E. F., Epps H. R., and Hla T. (1994) Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues: effects of interleukin-1β, phorbol ester, and corticosteroids. J. Clin. Invest. 93, 1095-1101.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1095-1101
    • Crofford, L.J.1    Wilder, R.L.2    Ristimäki, A.P.3    Sano, H.4    Remmers, E.F.5    Epps, H.R.6    Hla, T.7
  • 6
    • 0027499167 scopus 로고
    • Interleukin-1 receptors in the brain and endocrine tissues
    • Cunningham E. T. and De Souza E. B. (1993) Interleukin-1 receptors in the brain and endocrine tissues. Immunol. Today 14, 171-176.
    • (1993) Immunol. Today , vol.14 , pp. 171-176
    • Cunningham, E.T.1    De Souza, E.B.2
  • 7
    • 0025777448 scopus 로고
    • Interleukin-1 and interleukin-1 antagonism
    • Dinarello C. A. (1991) Interleukin-1 and interleukin-1 antagonism. Blood 77, 1627-1652.
    • (1991) Blood , vol.77 , pp. 1627-1652
    • Dinarello, C.A.1
  • 8
    • 0025021471 scopus 로고
    • Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist
    • Eisenberg S. P., Evans R. J., Arend W. P. L., Verderber E., Brewer M. T., Hannum C. H., and Thompson R. C. (1990) Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist. Nature 343, 341-346.
    • (1990) Nature , vol.343 , pp. 341-346
    • Eisenberg, S.P.1    Evans, R.J.2    Arend, W.P.L.3    Verderber, E.4    Brewer, M.T.5    Hannum, C.H.6    Thompson, R.C.7
  • 9
    • 0026589095 scopus 로고
    • Interleukin-1α and tumor necrosis factor-α differentially regulate enkephalin, vasoactive intestinal polypeptide, neurotensin, and substance P biosynthesis in chromaffin cells
    • Eskay R. L. and Eiden L. E. (1992) Interleukin-1α and tumor necrosis factor-α differentially regulate enkephalin, vasoactive intestinal polypeptide, neurotensin, and substance P biosynthesis in chromaffin cells. Endocrinology 130, 2252-2258.
    • (1992) Endocrinology , vol.130 , pp. 2252-2258
    • Eskay, R.L.1    Eiden, L.E.2
  • 11
    • 0023679882 scopus 로고
    • Interleukin-1β as a potent hyperalgesic agent antagonized by a tripeptide analogue
    • Ferreira S. H., Lorenzetti B. B., Bristow A. F., and Poole S. (1988) Interleukin-1β as a potent hyperalgesic agent antagonized by a tripeptide analogue. Nature 334, 698-700.
    • (1988) Nature , vol.334 , pp. 698-700
    • Ferreira, S.H.1    Lorenzetti, B.B.2    Bristow, A.F.3    Poole, S.4
  • 12
    • 0024330283 scopus 로고
    • Inhibition by neuropeptides of interleukin-1β-induced, prostaglandin-independent hyperalgesia
    • Follenfant R. L., Nakamura-Craig M., Henderson B., and Higgs G. A. (1989) Inhibition by neuropeptides of interleukin-1β-induced, prostaglandin-independent hyperalgesia. Br. J. Pharmacol. 98, 41-43.
    • (1989) Br. J. Pharmacol. , vol.98 , pp. 41-43
    • Follenfant, R.L.1    Nakamura-Craig, M.2    Henderson, B.3    Higgs, G.A.4
  • 13
    • 0026323939 scopus 로고
    • Cytokine regulation of substance P expression in sympathetic neurons
    • Freidin M. and Kessler J. A. (1991) Cytokine regulation of substance P expression in sympathetic neurons. Proc. Natl. Acad. Sci. USA 88, 3200-3203.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3200-3203
    • Freidin, M.1    Kessler, J.A.2
  • 14
    • 0027977895 scopus 로고
    • Cutaneous hyperalgesia induced by peripheral injection of interleukin-1β in the rat
    • Fukuoka H., Kawatani M., Hisamitsu T., and Takeshige C. (1994) Cutaneous hyperalgesia induced by peripheral injection of interleukin-1β in the rat. Brain Res. 657, 133-140.
    • (1994) Brain Res. , vol.657 , pp. 133-140
    • Fukuoka, H.1    Kawatani, M.2    Hisamitsu, T.3    Takeshige, C.4
  • 15
    • 0027201818 scopus 로고
    • Selective inhibition of NS-398 on prostanoid production in inflamed tissue in rat carrageenan-air-pouch inflammation
    • Futaki N., Arai I., Hamasaka Y., Takahashi S., Higuchi S., and Otomo S. (1993) Selective inhibition of NS-398 on prostanoid production in inflamed tissue in rat carrageenan-air-pouch inflammation. J. Pharm. Pharmacol. 45, 753-755.
    • (1993) J. Pharm. Pharmacol. , vol.45 , pp. 753-755
    • Futaki, N.1    Arai, I.2    Hamasaka, Y.3    Takahashi, S.4    Higuchi, S.5    Otomo, S.6
  • 17
    • 0027421621 scopus 로고
    • Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyterminal region of the cyclooxygenase-2
    • Habib A., Créminon C., Frobert Y., Grassi J., Pradelles P., and Maclouf J. (1993) Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyterminal region of the cyclooxygenase-2. J. Biol. Chem. 268, 23448-23454.
    • (1993) J. Biol. Chem. , vol.268 , pp. 23448-23454
    • Habib, A.1    Créminon, C.2    Frobert, Y.3    Grassi, J.4    Pradelles, P.5    Maclouf, J.6
  • 18
    • 0025947381 scopus 로고
    • Substance P gene expression is regulated by interleukin-1 in cultured sympathetic ganglia
    • Hart R. P., Shadiack A. M., and Jonakait G. M. (1991) Substance P gene expression is regulated by interleukin-1 in cultured sympathetic ganglia. J. Neurosci. Res. 29, 282-291.
    • (1991) J. Neurosci. Res. , vol.29 , pp. 282-291
    • Hart, R.P.1    Shadiack, A.M.2    Jonakait, G.M.3
  • 19
    • 0030049390 scopus 로고    scopus 로고
    • Proslaglandin synthase 2
    • Herschman H. R. (1996) Proslaglandin synthase 2. Biochim. Biophys. Acta 1299, 125-140.
    • (1996) Biochim. Biophys. Acta , vol.1299 , pp. 125-140
    • Herschman, H.R.1
  • 20
    • 0028021668 scopus 로고
    • Prostacyclin enhances the evoked-release of substance P and calcitonin gene-related peptide from rat sensory neurons
    • Hingtgen C. M. and Vasko M. R. (1994) Prostacyclin enhances the evoked-release of substance P and calcitonin gene-related peptide from rat sensory neurons. Brain Res. 655, 51-60.
    • (1994) Brain Res. , vol.655 , pp. 51-60
    • Hingtgen, C.M.1    Vasko, M.R.2
  • 21
    • 0029023042 scopus 로고
    • Prostaglandins facilitate peptide release from rat sensory neurons by activating the adenosine 3′,5′-cyclic monophosphate transduction cascade
    • Hingtgen C. M., Waite K. J., and Vasko M. R. (1995) Prostaglandins facilitate peptide release from rat sensory neurons by activating the adenosine 3′,5′-cyclic monophosphate transduction cascade. J. Neurosci. 15, 5411-5419.
    • (1995) J. Neurosci. , vol.15 , pp. 5411-5419
    • Hingtgen, C.M.1    Waite, K.J.2    Vasko, M.R.3
  • 22
    • 0022256343 scopus 로고
    • Met-enkephalin and morphine but not dynorphin inhibit noxious stimuli-induced release of substance P from rabbit dorsal horn in situ
    • Hirota N., Kuraishi Y., Hino Y., Sato Y., Satoh M., and Takagi H. (1985) Met-enkephalin and morphine but not dynorphin inhibit noxious stimuli-induced release of substance P from rabbit dorsal horn in situ. Neuropharmacology 24, 567-570.
    • (1985) Neuropharmacology , vol.24 , pp. 567-570
    • Hirota, N.1    Kuraishi, Y.2    Hino, Y.3    Sato, Y.4    Satoh, M.5    Takagi, H.6
  • 23
    • 0031025390 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine-facilitated release of substance P from rat spinal cord slices is mediated by nitric oxide and cyclic GMP
    • Inoue A., Hashimoto T., Hide I., Nishio H., and Nakata Y. (1997) 5-Hydroxytryptamine-facilitated release of substance P from rat spinal cord slices is mediated by nitric oxide and cyclic GMP. J. Neurochem. 68, 128-133.
    • (1997) J. Neurochem. , vol.68 , pp. 128-133
    • Inoue, A.1    Hashimoto, T.2    Hide, I.3    Nishio, H.4    Nakata, Y.5
  • 24
    • 0032052732 scopus 로고    scopus 로고
    • Differential effects on D2 dopamine receptor and prolactin gene expression by haloperidol and aripiprazole in the rat pituitary
    • Inoue A., Seto M., Sugita S., Hide I., Hirose T., Koga N., Kikuchi T., and Nakata Y. (1998) Differential effects on D2 dopamine receptor and prolactin gene expression by haloperidol and aripiprazole in the rat pituitary. Mol. Brain Res. 55, 285-292.
    • (1998) Mol. Brain Res. , vol.55 , pp. 285-292
    • Inoue, A.1    Seto, M.2    Sugita, S.3    Hide, I.4    Hirose, T.5    Koga, N.6    Kikuchi, T.7    Nakata, Y.8
  • 25
    • 0025281644 scopus 로고
    • Conditioned medium from activated splenocytes increases substance P in sympathetic ganglia
    • Jonakait G. M. and Schotland S. (1990) Conditioned medium from activated splenocytes increases substance P in sympathetic ganglia. J. Neurosci. Res. 26, 24-30.
    • (1990) J. Neurosci. Res. , vol.26 , pp. 24-30
    • Jonakait, G.M.1    Schotland, S.2
  • 26
    • 0027468941 scopus 로고
    • Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines
    • Jones D. A., Carlton D. P., McIntyre T. M., Zimmerman G. A., and Prescott S. M. (1993) Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines. J. Biol. Chem. 268, 9049-9054.
    • (1993) J. Biol. Chem. , vol.268 , pp. 9049-9054
    • Jones, D.A.1    Carlton, D.P.2    McIntyre, T.M.3    Zimmerman, G.A.4    Prescott, S.M.5
  • 27
  • 28
    • 0023753067 scopus 로고
    • Effect of neuropeptides on production of inflammatory cytokines by human monocytes
    • Lotz M., Vaughan J. H., and Carson D. A. (1988) Effect of neuropeptides on production of inflammatory cytokines by human monocytes. Science 241, 1218-1221.
    • (1988) Science , vol.241 , pp. 1218-1221
    • Lotz, M.1    Vaughan, J.H.2    Carson, D.A.3
  • 29
    • 0028203844 scopus 로고
    • Substance P enhances the secretion of tumor necrosis factor-α from neuroglial cells stimulated with lipopolysaccharide
    • Luber-Narod J., Kage R., and Leeman S. E. (1994) Substance P enhances the secretion of tumor necrosis factor-α from neuroglial cells stimulated with lipopolysaccharide. J. Immunol. 152, 819-824.
    • (1994) J. Immunol. , vol.152 , pp. 819-824
    • Luber-Narod, J.1    Kage, R.2    Leeman, S.E.3
  • 30
    • 0027230212 scopus 로고
    • Interleukin-1 differentially modulates chondrocyte expression of cyclooxygenase-2 and phospholipase A2
    • Lyons-Giordano B., Pratta M. A., Galbraith W., Davis G. L., and Arner E. C. (1993) Interleukin-1 differentially modulates chondrocyte expression of cyclooxygenase-2 and phospholipase A2. Exp. Cell Res. 206, 58-62.
    • (1993) Exp. Cell Res. , vol.206 , pp. 58-62
    • Lyons-Giordano, B.1    Pratta, M.A.2    Galbraith, W.3    Davis, G.L.4    Arner, E.C.5
  • 31
    • 0029670561 scopus 로고    scopus 로고
    • Effect of interleukin-1β on the release of substance P from rat isolated spinal cord
    • Malcangio M., Bowery N. G., Flower R. J., and Perretti M. (1996) Effect of interleukin-1β on the release of substance P from rat isolated spinal cord. Eur. J. Pharmacol. 299, 113-118.
    • (1996) Eur. J. Pharmacol. , vol.299 , pp. 113-118
    • Malcangio, M.1    Bowery, N.G.2    Flower, R.J.3    Perretti, M.4
  • 32
    • 0028052972 scopus 로고
    • Interleukin-1-induced cyclooxygenase 2 expression is suppressed by cyclosporin A in rat mesangial cells
    • Martin M., Neumann D., Hoff T., Resch K., DeWitt D. L., and Goppelt-Struebe M. (1994) Interleukin-1-induced cyclooxygenase 2 expression is suppressed by cyclosporin A in rat mesangial cells. Kidney Int. 45, 150-158.
    • (1994) Kidney Int. , vol.45 , pp. 150-158
    • Martin, M.1    Neumann, D.2    Hoff, T.3    Resch, K.4    DeWitt, D.L.5    Goppelt-Struebe, M.6
  • 34
    • 0028896787 scopus 로고
    • The formalin-induced expression of tachykinin peptide and neurokinin receptor messenger RNAs in rat sensory ganglia and spinal cord is modulated by opiate preadministration
    • McCarson K. E. and Krause J. E. (1995) The formalin-induced expression of tachykinin peptide and neurokinin receptor messenger RNAs in rat sensory ganglia and spinal cord is modulated by opiate preadministration. Neuroscience 64, 729-739.
    • (1995) Neuroscience , vol.64 , pp. 729-739
    • McCarson, K.E.1    Krause, J.E.2
  • 36
    • 0028105828 scopus 로고
    • Peptidergic pathway in human skin and rat peritoneal mast cell activation
    • Mousli M., Hugli T. E., Landry Y., and Bronner C. (1994) Peptidergic pathway in human skin and rat peritoneal mast cell activation. Immunopharmacology 27, 1-11.
    • (1994) Immunopharmacology , vol.27 , pp. 1-11
    • Mousli, M.1    Hugli, T.E.2    Landry, Y.3    Bronner, C.4
  • 37
    • 0026735231 scopus 로고
    • cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase
    • O'Banion M. K., Winn V. D., and Young D. A. (1992) cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc. Natl. Acad. Sci. USA 89, 4888-4892.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4888-4892
    • O'Banion, M.K.1    Winn, V.D.2    Young, D.A.3
  • 38
    • 0029953089 scopus 로고    scopus 로고
    • Interleukin-1β induces prostaglandin G/H synthase-2 (cyclooxygenase-2) in primary murine astrocyte cultures
    • O'Banion M. K., Miller J. C., Chang J. W., Kaplan M. D., and Coleman P. D. (1996) Interleukin-1β induces prostaglandin G/H synthase-2 (cyclooxygenase-2) in primary murine astrocyte cultures. J. Neurochem. 66, 2532-2540.
    • (1996) J. Neurochem. , vol.66 , pp. 2532-2540
    • O'Banion, M.K.1    Miller, J.C.2    Chang, J.W.3    Kaplan, M.D.4    Coleman, P.D.5
  • 39
    • 0025307153 scopus 로고
    • Elevated substance P and accelerated cartilage degradation in rabbit knees injected with interleukin-1 and tumor necrosis factor
    • O'Byrne E. M., Blancuzzi V., Wilson D. E., Wong M., and Jeng A. Y. (1990) Elevated substance P and accelerated cartilage degradation in rabbit knees injected with interleukin-1 and tumor necrosis factor. Arthritis Rheum. 33, 1023-1028.
    • (1990) Arthritis Rheum. , vol.33 , pp. 1023-1028
    • O'Byrne, E.M.1    Blancuzzi, V.2    Wilson, D.E.3    Wong, M.4    Jeng, A.Y.5
  • 41
    • 0030583623 scopus 로고    scopus 로고
    • Inhibition of peripheral interleukin-1β-induced hyperalgesia by the intracerebroventricular administration of diclofenac and α-melanocyte-stimulating hormone
    • Oka T., Oka K., Hosoi M., and Hori T. (1996) Inhibition of peripheral interleukin-1β-induced hyperalgesia by the intracerebroventricular administration of diclofenac and α-melanocyte-stimulating hormone. Brain Res. 736, 237-242.
    • (1996) Brain Res. , vol.736 , pp. 237-242
    • Oka, T.1    Oka, K.2    Hosoi, M.3    Hori, T.4
  • 42
    • 0016835147 scopus 로고
    • Hypothalamic substance P as a candidate for transmitter of primary afferent neurons
    • Otsuka M., Konishi S., and Takahashi T. (1975) Hypothalamic substance P as a candidate for transmitter of primary afferent neurons. Fed. Proc. 34, 1922-1928.
    • (1975) Fed. Proc. , vol.34 , pp. 1922-1928
    • Otsuka, M.1    Konishi, S.2    Takahashi, T.3
  • 43
    • 0027358551 scopus 로고
    • Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: Involvement of NK-1 receptors
    • Perretti M., Ahluwalia A., Flower R. J., and Manzini S. (1993) Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: involvement of NK-1 receptors. Immunology 80, 73-77.
    • (1993) Immunology , vol.80 , pp. 73-77
    • Perretti, M.1    Ahluwalia, A.2    Flower, R.J.3    Manzini, S.4
  • 44
    • 0017408837 scopus 로고
    • Effect of substance P in cat dorsal horn neurons activated by noxious stimuli
    • Randic M. and Miletic V. (1977) Effect of substance P in cat dorsal horn neurons activated by noxious stimuli. Brain Res. 128, 164-169.
    • (1977) Brain Res. , vol.128 , pp. 164-169
    • Randic, M.1    Miletic, V.2
  • 45
    • 0030822876 scopus 로고    scopus 로고
    • Involvement of interleukin-1β, nerve growth factor and prostaglandin E2 in endotoxin-induced localized inflammatory hyperalgesia
    • Safieh-Garabedian B., Kanaan S. A., Haddad J. J., Jaoude P. A., Jabbur S. J., and Saadé N. E. (1997) Involvement of interleukin-1β, nerve growth factor and prostaglandin E2 in endotoxin-induced localized inflammatory hyperalgesia. Br. J. Pharmacol. 121, 1619-1626.
    • (1997) Br. J. Pharmacol. , vol.121 , pp. 1619-1626
    • Safieh-Garabedian, B.1    Kanaan, S.A.2    Haddad, J.J.3    Jaoude, P.A.4    Jabbur, S.J.5    Saadé, N.E.6
  • 46
    • 0027161441 scopus 로고
    • Interleukin-1 induces substance P in sympathetic ganglia through the induction of leukemia inhibitory factor (LIF)
    • Shadiack A. M., Hart R. P., Carlson C. D., and Jonakait G. M. (1993) Interleukin-1 induces substance P in sympathetic ganglia through the induction of leukemia inhibitory factor (LIF). J. Neurosci. 13, 2601-2609.
    • (1993) J. Neurosci. , vol.13 , pp. 2601-2609
    • Shadiack, A.M.1    Hart, R.P.2    Carlson, C.D.3    Jonakait, G.M.4
  • 47
    • 0026586644 scopus 로고
    • Peripheral and central mechanisms of cutaneous hyperalgesia
    • Treede R, D., Meyer R. A., Raja S. N., and Campbell J. N. (1992) Peripheral and central mechanisms of cutaneous hyperalgesia. Prog. Neurobiol. 38, 397-421.
    • (1992) Prog. Neurobiol. , vol.38 , pp. 397-421
    • Treede, R.D.1    Meyer, R.A.2    Raja, S.N.3    Campbell, J.N.4
  • 49
    • 0028917098 scopus 로고
    • Substance P-induced inflammatory responses in guinea-pig skin: The effect of specific NK1 receptor antagonists and the role of endogenous mediators
    • Walsh D. T., Weg V. B., Williams T. J., and Nourshargh S. (1995) Substance P-induced inflammatory responses in guinea-pig skin: the effect of specific NK1 receptor antagonists and the role of endogenous mediators. Br. J. Pharmacol. 114, 1343-1350.
    • (1995) Br. J. Pharmacol. , vol.114 , pp. 1343-1350
    • Walsh, D.T.1    Weg, V.B.2    Williams, T.J.3    Nourshargh, S.4
  • 51
    • 0028805882 scopus 로고
    • Immune activation: The role of pro-inflammatory cytokines in inflammation, illness responses and pathological pain states
    • Watkins L. R., Maier S. F., and Goehler L. E. (1995) Immune activation: the role of pro-inflammatory cytokines in inflammation, illness responses and pathological pain states. Pain 63, 289-302.
    • (1995) Pain , vol.63 , pp. 289-302
    • Watkins, L.R.1    Maier, S.F.2    Goehler, L.E.3
  • 52
    • 0029874726 scopus 로고    scopus 로고
    • Biphasic effects of intracerebroventricular interleukin-1β on mechanical nociception in the rat
    • Yabuuchi K., Nishiyori A., Minami M., and Satoh M. (1996) Biphasic effects of intracerebroventricular interleukin-1β on mechanical nociception in the rat. Eur. J. Pharmacol. 300, 59-65.
    • (1996) Eur. J. Pharmacol. , vol.300 , pp. 59-65
    • Yabuuchi, K.1    Nishiyori, A.2    Minami, M.3    Satoh, M.4


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