Peroxisome proliferator-activated receptor γ up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis

Journal of Biological Chemistry

Volumn 282, Issue 51, 2007, Pages 37006-37015

  Fuenzalida, Karen ^a   Quintanilla, Rodrigo ^a   Ramos, Patricio ^a   Piderit, Daniela ^a   Fuentealba, Rodrigo A ^a   Martinez, Gabriela ^a   Inestrosa, Nibaldo C ^a   Bronfman, Miguel ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; DISEASES; MORPHOLOGY; NEURONS; OXIDATIVE STRESS; RNA;

ANTI-INFLAMMATORY ACTION; MITOCHONDRIAL STABILIZATION; NERVE GROWTH FACTOR (NGF); NEURODEGENERATIVE DISEASES; REACTIVE OXYGEN SPECIES;

PROTEINS;

2 CHLORO 5 NITROBENZANILIDE; AMYLOID BETA PROTEIN; HYDROGEN PEROXIDE; MUTANT PROTEIN; NERVE GROWTH FACTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; ROSIGLITAZONE; SMALL INTERFERING RNA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GLIA CELL; HIPPOCAMPUS; MITOCHONDRION; NERVE CELL DIFFERENTIATION; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; SPINAL GANGLION;

AMYLOID BETA-PROTEIN; ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL SURVIVAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GANGLIA, SPINAL; HIPPOCAMPUS; HYDROGEN PEROXIDE; HYPOGLYCEMIC AGENTS; MICE; MITOCHONDRIA; NERVE GROWTH FACTOR; NEURODEGENERATIVE DISEASES; NEUROGLIA; NEURONS; OXIDANTS; OXIDATIVE STRESS; PC12 CELLS; PPAR GAMMA; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RNA, SMALL INTERFERING; THIAZOLIDINEDIONES;

EID: 37549060702     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700447200     Document Type: Article

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