Transgenic murine cortical neurons expressing human Bcl-2 exhibit increased resistance to amyloid β-peptide neurotoxicity

Neuroscience

Volumn 92, Issue 4, 1999, Pages 1455-1463

  Saille C ^a   Marin, P ^b   Martinou, J C ^c   Nicole, A ^a   London, J ^a   Ceballos Picot, I ^a  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

^b INSERM   (France)

^c SERONO PHARMACEUTICAL RES INSTITUTE   (Switzerland)

Author keywords

Alzheimer's disease; Amyloid peptide; Apoptosis; Bcl 2; Copper zinc superoxide dismutase; Neuroprotection

Indexed keywords

AMYLOID BETA PROTEIN; COPPER ZINC SUPEROXIDE DISMUTASE; PEROXYNITRITE; PROTEIN BCL 2; SUPEROXIDE;

ALZHEIMER DISEASE; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; CONTROLLED STUDY; EMBRYO; GENE OVEREXPRESSION; GENE THERAPY; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; TRANSGENE;

AMYLOID BETA-PROTEIN; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; GENE EXPRESSION; GENES, BCL-2; HUMANS; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; NEUROTOXINS; SUPEROXIDE DISMUTASE;

EID: 0033011662     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00089-5     Document Type: Article

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